Team game results -- 2022 Chicago White Sox
Regular season
| Primary |
| Date | # | | Opp | | Score | Inn | Starter | T | Decision | Save | Versus | T |
| 4/8/2022 | | |  Bal | W | 11-6 | | Bassitt | R | Fry,P | | Montgomery | L |
| 4/8/2022 | | @ |  LAA | L | 1-6 | | Giolito | R | Giolito | | Gibson | R |
| 4/9/2022 | | | Bal | W | 10-5 | | Ohtani | R | Ohtani | | Dunning | R |
| 4/9/2022 | | @ | LAA | W | 6-4 | | Ohtani | R | Ohtani | Rogers,Ty | Keuchel | L |
| 4/10/2022 | | | Bal | L | 1-5 | | Cortes | L | Rodriguez,M | | Foltynewicz | R |
| 4/10/2022 | | @ | LAA | W | 7-3 | | Bassitt | R | Bassitt | | Pineda | R |
| 4/11/2022 | | | Bal | W | 7-6 | | Giolito | R | Neris | Rogers,Ty | Richards,G | R |
| 4/11/2022 | | @ | LAA | L | 5-12 | | Ober | R | Ober | | Manoah | R |
| 4/12/2022 | | @ |  Tor | L | 3-4 | | Cortes | L | Cortes | | Arrieta | R |
| 4/12/2022 | | |  Cle | W | 8-5 | | Ober | R | Rogers,Ty | Cisnero | Skubal | L |
| 4/13/2022 | | @ | Tor | W | 4-3 | | Giolito | R | Giolito | Conley | Ryu | L |
| 4/13/2022 | | | Cle | L | 5-8 | | Bassitt | R | Bassitt | | Hendricks | R |
| 4/14/2022 | | @ | Tor | W | 5-0 | | Ohtani | R | Ohtani | | Freeland | L |
| 4/14/2022 | | | Cle | W | 8-1 | | Ohtani | R | Ohtani | | Davidson | L |
| 4/16/2022 | | | Tor | W | 5-2 | | Cortes | L | Cortes | | Cueto | R |
| 4/16/2022 | | @ | Cle | L | 1-14 | | Ober | R | Ober | | Skubal | L |
| 4/17/2022 | | | Tor | L | 5-8 | | Giolito | R | Cisnero | | Arrieta | R |
| 4/17/2022 | | @ | Cle | L | 4-5 | | Cortes | L | Rogers,Ty | | Keller,M | R |
| 4/18/2022 | | | Tor | W | 18-14 | | Bassitt | R | Bassitt | | Ryu | L |
| 4/18/2022 | | @ | Cle | W | 5-3 | | Giolito | R | Giolito | Conley | Hendricks | R |
| 4/22/2022 | | |  SFG | W | 7-2 | | Cortes | L | Cortes | | Buehler | R |
| 4/23/2022 | | | SFG | W | 3-0 | | Ohtani | R | Ohtani | Cisnero | Anderson,Ty | L |
| 4/24/2022 | | | SFG | L | 3-5 | | Ober | R | Ober | | Wheeler | R |
| 4/26/2022 | | |  LAD | L | 1-3 | | Bassitt | R | Bassitt | | Musgrove | R |
| 4/27/2022 | | | LAD | L | 2-9 | | Giolito | R | Giolito | | McKenzie | R |
| 4/28/2022 | | | LAD | L | 4-5 | 13 | Cortes | L | Rogers,Ty | | May,D | R |
| 5/2/2022 | | |  Was | W | 6-5 | | Cortes | L | Cortes | Rogers,Ty | Pivetta | R |
| 5/2/2022 | | @ |  Tex | W | 9-2 | | Bassitt | R | Bassitt | | Matz | L |
| 5/3/2022 | | | Was | W | 11-7 | | Ohtani | R | Neris | | Burnes | R |
| 5/3/2022 | | @ | Tex | W | 5-4 | | Ohtani | R | Ohtani | Cisnero | Gomber | L |
| 5/4/2022 | | | Was | W | 23-9 | | Ober | R | Zimmer,K | | Kuhl | R |
| 5/4/2022 | | @ | Tex | L | 2-3 | | Ober | R | Neris | | Wacha | R |
| 5/5/2022 | | | Was | L | 5-8 | | Bassitt | R | Bassitt | | Hearn | L |
| 5/5/2022 | | @ | Tex | L | 1-5 | | Cortes | L | Cortes | | Manaea | L |
| 5/6/2022 | | @ |  Hou | L | 2-3 | | Giolito | R | Cisnero | | Anderson,D | R |
| 5/7/2022 | | @ | Hou | W | 4-1 | | Bassitt | R | Bassitt | Fry,P | Cease | R |
| 5/8/2022 | | @ | Hou | L | 0-4 | | Ohtani | R | Ohtani | | Sale | L |
| 5/10/2022 | | @ |  ChC | W | 3-2 | | Ober | R | Ober | Rogers,Ty | Flexen | R |
| 5/11/2022 | | @ | ChC | W | 6-0 | | Cortes | L | Cortes | | Paddack | R |
| 5/12/2022 | | @ | ChC | W | 9-0 | | Giolito | R | Giolito | | Smith,C | L |
| 5/23/2022 | | |  Mtl | W | 1-0 | | Peralta,Wi | R | Peralta,Wi | Rogers,Ty | Yarbrough | L |
| 5/23/2022 | | @ |  Oak | L | 3-7 | | Peralta,Wi | R | Peralta,Wi | | Archer | R |
| 5/24/2022 | | | Mtl | W | 8-5 | | Giolito | R | Giolito | Fry,P | Lopez,P | R |
| 5/24/2022 | | @ | Oak | L | 1-2 | 10 | Bassitt | R | Rodriguez,M | | Knehr | R |
| 5/25/2022 | | | Mtl | W | 6-4 | | Ober | R | Ober | Santana,Ed | Bumgarner | L |
| 5/25/2022 | | @ | Oak | W | 7-2 | | Ohtani | R | Ohtani | Neris | Cole,G | R |
| 5/26/2022 | | | Mtl | L | 4-7 | | Bassitt | R | Bassitt | | Junk | R |
| 5/26/2022 | | @ | Oak | W | 4-2 | | Ober | R | Santana,Ed | Neris | Quantrill | R |
| 5/27/2022 | | |  Det | W | 15-3 | | Ohtani | R | Ohtani | | Williams,Tr | R |
| 5/27/2022 | | @ |  Min | L | 1-2 | | Giolito | R | Cisnero | | Rasmussen | R |
| 5/28/2022 | | | Det | L | 2-8 | | Peralta,Wi | R | Peralta,Wi | | Rogers,Tr | L |
| 5/28/2022 | | @ | Min | W | 3-2 | | Peralta,Wi | R | Neris | Fry,P | Lauer | L |
| 5/29/2022 | | | Det | W | 12-4 | | Giolito | R | Giolito | | Hill,R | L |
| 5/29/2022 | | @ | Min | W | 11-2 | | Bassitt | R | Bassitt | | Urias,J | L |
| 5/31/2022 | | @ | Bal | W | 5-2 | | Ohtani | R | Conley | | Montgomery | L |
| 5/31/2022 | | | Tex | W | 4-3 | | Ober | R | Ober | Neris | Manaea | L |
| 6/1/2022 | | @ | Bal | W | 6-2 | | Ober | R | Santana,Ed | Zimmer,K | Dunning | R |
| 6/1/2022 | | | Tex | W | 10-1 | | Bassitt | R | Bassitt | | Matz | L |
| 6/2/2022 | | @ | Bal | W | 15-5 | | Peralta,Wi | R | Hernandez,D | | Megill,Ty | R |
| 6/2/2022 | | | Tex | W | 2-1 | | Ohtani | R | Neris | | Alzolay | R |
| 6/3/2022 | | @ | Bal | W | 8-2 | | Giolito | R | Giolito | | Foltynewicz | R |
| 6/3/2022 | | | Tex | W | 4-2 | | Peralta,Wi | R | Rodriguez,M | Cisnero | Gomber | L |
| 6/7/2022 | | |  Ari | W | 6-4 | | Peralta,Wi | R | Neris | Rogers,Ty | Kikuchi | L |
| 6/8/2022 | | | Ari | W | 10-2 | | Ohtani | R | Ohtani | | Otto | R |
| 6/9/2022 | | | Ari | W | 1-0 | | Bassitt | R | Neris | Clippard | Gray,Jon | R |
| 6/10/2022 | | |  SDP | W | 4-1 | | Ober | R | Ober | Rogers,Ty | Minor | L |
| 6/11/2022 | | | SDP | L | 1-8 | | Giolito | R | Giolito | | Scherzer | R |
| 6/12/2022 | | | SDP | W | 11-4 | | Peralta,Wi | R | Fry,P | | Smith,R | R |
| 6/14/2022 | | |  Col | W | 9-5 | | Ohtani | R | Ohtani | | Hudson,Dak | R |
| 6/15/2022 | | | Col | W | 11-6 | | Bassitt | R | Bassitt | | Davies | R |
| 6/16/2022 | | | Col | W | 13-3 | | Ober | R | Ober | | Crowe | R |
| 6/17/2022 | | @ |  StL | W | 10-5 | | Ohtani | R | Rogers,Ty | Zimmer,K | Mize | R |
| 6/18/2022 | | @ | StL | W | 4-2 | | Ober | R | Rogers,Ty | Santana,Ed | Woodruff | R |
| 6/19/2022 | | @ | StL | L | 0-4 | | Peralta,Wi | R | Peralta,Wi | | McCullers | R |
| 6/21/2022 | | @ |  Cin | W | 11-3 | | Giolito | R | Giolito | | Ynoa | R |
| 6/22/2022 | | @ | Cin | W | 6-4 | | Bassitt | R | Neris | Conley | Peralta,F | R |
| 6/23/2022 | | @ | Cin | L | 3-6 | | Ohtani | R | Ohtani | | Taillon | R |
| 6/24/2022 | | @ |  Mil | L | 5-14 | | Peralta,Wi | R | Peralta,Wi | | Darvish | R |
| 6/25/2022 | | @ | Mil | L | 1-3 | | Ober | R | Ober | | Lowther | L |
| 6/26/2022 | | @ | Mil | W | 9-3 | | Giolito | R | Giolito | | Civale | R |
| 7/14/2022 | | |  Bos | W | 2-1 | | Giolito | R | Giolito | Neris | Rodriguez,Ed | L |
| 7/14/2022 | | @ |  Sea | W | 10-1 | | Cortes | L | Cortes | | Odorizzi | R |
| 7/15/2022 | | | Bos | W | 7-5 | | Cortes | L | Cisnero | Zimmer,K | Lester | L |
| 7/15/2022 | | @ | Sea | W | 10-1 | | Bassitt | R | Bassitt | | Harvey,M | R |
| 7/16/2022 | | | Bos | W | 6-4 | | Bassitt | R | Bassitt | Neris | Gutierrez,V | R |
| 7/16/2022 | | @ | Sea | L | 2-3 | | Peralta,Wi | R | Conley | | Cabrera,E | R |
| 7/17/2022 | | | Bos | L | 1-6 | | Peralta,Wi | R | Peralta,Wi | | Gonzalez,C | R |
| 7/17/2022 | | @ | Sea | W | 4-3 | 13 | Giolito | R | Neris | Santana,Ed | Martinez,C | R |
| 7/18/2022 | | | Min | L | 6-9 | 10 | Ohtani | R | Cisnero | | Ray,R | L |
| 7/18/2022 | | @ | Det | W | 5-2 | | Ohtani | R | Ohtani | Zimmer,K | Rogers,Tr | L |
| 7/19/2022 | | | Min | W | 7-2 | | Giolito | R | Giolito | | Lauer | L |
| 7/19/2022 | | @ | Det | W | 10-6 | | Cortes | L | Cortes | | Williams,Tr | R |
| 7/20/2022 | | | Min | L | 1-2 | | Cortes | L | Cortes | | Urias,J | L |
| 7/20/2022 | | @ | Det | W | 4-3 | | Bassitt | R | Conley | Zimmer,K | Anderson,Bre | L |
| 7/22/2022 | | @ | Bos | W | 11-6 | | Peralta,Wi | R | Neris | | Gonzalez,C | R |
| 7/22/2022 | | |  KCR | W | 8-3 | | Peralta,Wi | R | Fry,P | Santana,Ed | Bubic | L |
| 7/23/2022 | | @ | Bos | L | 3-4 | | Giolito | R | Zimmer,K | | Gutierrez,V | R |
| 7/23/2022 | | | KCR | W | 7-1 | | Bassitt | R | Bassitt | | Brubaker | R |
| 7/24/2022 | | @ | Bos | W | 5-2 | | Ohtani | R | Ohtani | Santana,Ed | Rodriguez,Ed | L |
| 7/24/2022 | | | KCR | L | 1-4 | | Giolito | R | Giolito | | Greinke | R |
| 7/25/2022 | | @ | Bos | L | 4-5 | 12 | Cortes | L | Conley | | Miley | L |
| 7/25/2022 | | | KCR | L | 1-4 | | Ohtani | R | Ohtani | | Montas | R |
| 8/5/2022 | | | Tor | W | 4-3 | 13 | Kowar | R | Hernandez,D | | Mills,A | R |
| 8/5/2022 | | @ | Cle | W | 17-6 | 10 | Bassitt | R | Quijada | | Keller,B | R |
| 8/6/2022 | | | Tor | W | 9-7 | | Ohtani | R | Ohtani | Fry,P | Freeland | L |
| 8/6/2022 | | @ | Cle | L | 3-9 | | Giolito | R | Giolito | | Oviedo,J | R |
| 8/7/2022 | | | Tor | W | 3-1 | | Bassitt | R | Bassitt | Neris | Stripling | R |
| 8/7/2022 | | @ | Cle | L | 2-4 | 11 | Ohtani | R | Hernandez,D | | Hendricks | R |
| 8/8/2022 | | @ | Tor | W | 7-3 | | Kowar | R | Conley | | Berrios | R |
| 8/8/2022 | | | Cle | W | 7-5 | | Peralta,Wi | R | Neris | Rogers,Ty | Rogers,Jo | L |
| 8/9/2022 | | @ | Tor | L | 5-8 | | Peralta,Wi | R | Quijada | | Ryu | L |
| 8/9/2022 | | | Cle | W | 9-1 | | Giolito | R | Giolito | | Oviedo,J | R |
| 8/10/2022 | | @ | Tor | L | 3-5 | | Bassitt | R | Bassitt | | Mills,A | R |
| 8/10/2022 | | | Cle | W | 6-2 | | Kowar | R | Quijada | Rogers,Ty | Hendricks | R |
| 8/12/2022 | | @ |  NYY | L | 1-6 | | Giolito | R | Giolito | | Gray,Jos | R |
| 8/12/2022 | | | LAA | W | 12-1 | | Bassitt | R | Bassitt | | Widener | R |
| 8/13/2022 | | @ | NYY | L | 3-7 | | Kowar | R | Cisnero | | Flaherty | R |
| 8/13/2022 | | | LAA | L | 1-3 | | Peralta,Wi | R | Peralta,Wi | | Manoah | R |
| 8/14/2022 | | @ | NYY | L | 1-2 | 11 | Peralta,Wi | R | Santana,Ed | | Gonzales | L |
| 8/14/2022 | | | LAA | W | 5-4 | | Giolito | R | Quijada | | Houck | R |
| 8/15/2022 | | @ | NYY | W | 7-4 | | Bassitt | R | Bassitt | | Happ,JA | L |
| 8/15/2022 | | | LAA | W | 6-4 | | Kowar | R | Cisnero | Conley | Eflin | R |
| 8/22/2022 | | | Sea | W | 5-3 | | Bassitt | R | Bassitt | Fry,P | Zimmermann,B | L |
| 8/22/2022 | | @ | Was | L | 1-3 | | Giolito | R | Giolito | | Kuhl | R |
| 8/23/2022 | | | Sea | W | 14-4 | | Kowar | R | Kowar | Diplan | Dunn | R |
| 8/23/2022 | | @ | Was | L | 3-4 | | Kowar | R | Rogers,Ty | | Burnes | R |
| 8/24/2022 | | | Sea | W | 7-3 | | Ober | R | Ober | | Perez,Ma | L |
| 8/24/2022 | | @ | Was | L | 3-7 | | Ober | R | Ober | | Pivetta | R |
| 8/25/2022 | | | Sea | L | 4-7 | | Peralta,Wi | R | Rogers,Ty | | Harvey,M | R |
| 8/25/2022 | | @ | Was | L | 6-7 | 11 | Bassitt | R | Rogers,Ty | | Castellanos,H | R |
| 8/26/2022 | | @ | Mtl | W | 4-1 | 10 | Peralta,Wi | R | Diplan | Neris | Fleming | L |
| 8/26/2022 | | | Oak | W | 6-5 | 12 | Giolito | R | Diplan | | Walker,T | R |
| 8/27/2022 | | @ | Mtl | W | 9-0 | | Giolito | R | Giolito | | Lopez,P | R |
| 8/27/2022 | | | Oak | W | 4-3 | | Bassitt | R | Bassitt | Clippard | Muller | L |
| 8/28/2022 | | @ | Mtl | L | 2-7 | | Kowar | R | Kowar | | Bumgarner | L |
| 8/28/2022 | | | Oak | L | 4-10 | | Kowar | R | Kowar | | Hoffman | R |
| 8/29/2022 | | @ | Mtl | L | 3-4 | 10 | Ober | R | Clippard | | Lynch | L |
| 8/29/2022 | | | Oak | L | 5-9 | | Ober | R | Ober | | Quantrill | R |
| 9/6/2022 | | | Det | W | 11-3 | | Ober | R | Ober | Neris | McCullers | R |
| 9/6/2022 | | @ | Min | L | 3-5 | | Ohtani | R | Neris | | Gallen | R |
| 9/7/2022 | | | Det | W | 4-2 | | Ohtani | R | Ohtani | Quijada | Rogers,Tr | L |
| 9/7/2022 | | @ | Min | L | 1-5 | | Giolito | R | Giolito | | Ray,R | L |
| 9/8/2022 | | | Det | W | 10-4 | | Cortes | L | Cortes | | Poteet | R |
| 9/8/2022 | | @ | Min | L | 1-7 | | Cortes | L | Cortes | | Urias,J | L |
| 9/9/2022 | | | NYY | W | 9-0 | | Peralta,Wi | R | Peralta,Wi | | Morgan,E | R |
| 9/9/2022 | | @ | KCR | L | 0-9 | | Ober | R | Ober | | Hernandez,El | R |
| 9/10/2022 | | | NYY | W | 15-5 | | Kowar | R | Rogers,Ty | Diplan | Hentges | L |
| 9/10/2022 | | @ | KCR | L | 0-7 | | Bassitt | R | Bassitt | | Montas | R |
| 9/11/2022 | | | NYY | W | 16-5 | | Ober | R | Ober | | Barnes,C | L |
| 9/11/2022 | | @ | KCR | W | 4-3 | | Ohtani | R | Neris | Santana,Ed | Bubic | L |
| 9/12/2022 | | | NYY | W | 7-2 | | Ohtani | R | Ohtani | | Cahill | R |
| 9/12/2022 | | @ | KCR | W | 12-7 | | Giolito | R | Giolito | | Brubaker | R |
| 9/23/2022 | | | Min | L | 4-6 | 11 | Peralta,Wi | R | Cisnero | | Turnbull | R |
| 9/23/2022 | | @ | Det | L | 2-3 | 10 | Cortes | L | Fry,P | | Poteet | R |
| 9/24/2022 | | | Min | W | 3-0 | | Giolito | R | Giolito | Diplan | Urias,J | L |
| 9/24/2022 | | @ | Det | W | 17-5 | | Ober | R | Ober | | Contreras,R | R |
| 9/25/2022 | | | Min | L | 3-4 | | Bassitt | R | Quijada | | Ray,R | L |
| 9/25/2022 | | @ | Det | W | 2-1 | | Bassitt | R | Bassitt | Neris | Webb,L | R |
| 9/26/2022 | | | Det | W | 11-7 | | Ober | R | Quijada | Santana,Ed | McCullers | R |
| 9/26/2022 | | @ | Min | L | 2-4 | | Ohtani | R | Ohtani | | Turnbull | R |
| 9/27/2022 | | | Det | W | 2-0 | | Cortes | L | Cortes | Santana,Ed | Rogers,Tr | L |
| 9/27/2022 | | @ | Min | L | 9-12 | | Giolito | R | Neris | | Urias,J | L |
| Other |
| Game information | | Cumulative |
| Date | # | | Opp | | GWRBI | RF | RA | | W | L | Pct | L10 | Strk | Gm# |
| 4/8/2022 | | | Bal | W | | 11 | 6 | | 1 | 0 | 1.000 | 1-0 | W1 | 1 |
| 4/8/2022 | | @ | LAA | L | | 1 | 6 | | 1 | 1 | .500 | 1-1 | L1 | 2 |
| 4/9/2022 | | | Bal | W | Ohtani | 10 | 5 | | 2 | 1 | .667 | 2-1 | W1 | 3 |
| 4/9/2022 | | @ | LAA | W | Castellanos,N | 6 | 4 | | 3 | 1 | .750 | 3-1 | W2 | 4 |
| 4/10/2022 | | | Bal | L | | 1 | 5 | | 3 | 2 | .600 | 3-2 | L1 | 5 |
| 4/10/2022 | | @ | LAA | W | Jimenez,E | 7 | 3 | | 4 | 2 | .667 | 4-2 | W1 | 6 |
| 4/11/2022 | | | Bal | W | Castellanos,N | 7 | 6 | | 5 | 2 | .714 | 5-2 | W2 | 7 |
| 4/11/2022 | | @ | LAA | L | | 5 | 12 | | 5 | 3 | .625 | 5-3 | L1 | 8 |
| 4/12/2022 | | @ | Tor | L | | 3 | 4 | | 5 | 4 | .556 | 5-4 | L2 | 9 |
| 4/12/2022 | | | Cle | W | Pujols | 8 | 5 | | 6 | 4 | .600 | 6-4 | W1 | 10 |
| 4/13/2022 | | @ | Tor | W | Jimenez,E | 4 | 3 | | 7 | 4 | .636 | 6-4 | W2 | 11 |
| 4/13/2022 | | | Cle | L | | 5 | 8 | | 7 | 5 | .583 | 6-4 | L1 | 12 |
| 4/14/2022 | | @ | Tor | W | Castellanos,N | 5 | 0 | | 8 | 5 | .615 | 6-4 | W1 | 13 |
| 4/14/2022 | | | Cle | W | Harper,B | 8 | 1 | | 9 | 5 | .643 | 6-4 | W2 | 14 |
| 4/16/2022 | | | Tor | W | Castellanos,N | 5 | 2 | | 10 | 5 | .667 | 7-3 | W3 | 15 |
| 4/16/2022 | | @ | Cle | L | | 1 | 14 | | 10 | 6 | .625 | 6-4 | L1 | 16 |
| 4/17/2022 | | | Tor | L | | 5 | 8 | | 10 | 7 | .588 | 5-5 | L2 | 17 |
| 4/17/2022 | | @ | Cle | L | | 4 | 5 | | 10 | 8 | .556 | 5-5 | L3 | 18 |
| 4/18/2022 | | | Tor | W | Turner,J | 18 | 14 | | 11 | 8 | .579 | 6-4 | W1 | 19 |
| 4/18/2022 | | @ | Cle | W | Albies | 5 | 3 | | 12 | 8 | .600 | 6-4 | W2 | 20 |
| 4/22/2022 | | | SFG | W | Posey | 7 | 2 | | 13 | 8 | .619 | 6-4 | W3 | 21 |
| 4/23/2022 | | | SFG | W | Turner,J | 3 | 0 | | 14 | 8 | .636 | 7-3 | W4 | 22 |
| 4/24/2022 | | | SFG | L | | 3 | 5 | | 14 | 9 | .609 | 6-4 | L1 | 23 |
| 4/26/2022 | | | LAD | L | | 1 | 3 | | 14 | 10 | .583 | 5-5 | L2 | 24 |
| 4/27/2022 | | | LAD | L | | 2 | 9 | | 14 | 11 | .560 | 4-6 | L3 | 25 |
| 4/28/2022 | | | LAD | L | | 4 | 5 | | 14 | 12 | .538 | 4-6 | L4 | 26 |
| 5/2/2022 | | | Was | W | Garcia,Le | 6 | 5 | | 15 | 12 | .556 | 5-5 | W1 | 27 |
| 5/2/2022 | | @ | Tex | W | Ohtani | 9 | 2 | | 16 | 12 | .571 | 6-4 | W2 | 28 |
| 5/3/2022 | | | Was | W | Posey | 11 | 7 | | 17 | 12 | .586 | 6-4 | W3 | 29 |
| 5/3/2022 | | @ | Tex | W | Garcia,Le | 5 | 4 | | 18 | 12 | .600 | 6-4 | W4 | 30 |
| 5/4/2022 | | | Was | W | Albies | 23 | 9 | | 19 | 12 | .613 | 6-4 | W5 | 31 |
| 5/4/2022 | | @ | Tex | L | | 2 | 3 | | 19 | 13 | .594 | 5-5 | L1 | 32 |
| 5/5/2022 | | | Was | L | | 5 | 8 | | 19 | 14 | .576 | 5-5 | L2 | 33 |
| 5/5/2022 | | @ | Tex | L | | 1 | 5 | | 19 | 15 | .559 | 5-5 | L3 | 34 |
| 5/6/2022 | | @ | Hou | L | | 2 | 3 | | 19 | 16 | .543 | 5-5 | L4 | 35 |
| 5/7/2022 | | @ | Hou | W | Simmons | 4 | 1 | | 20 | 16 | .556 | 6-4 | W1 | 36 |
| 5/8/2022 | | @ | Hou | L | | 0 | 4 | | 20 | 17 | .541 | 5-5 | L1 | 37 |
| 5/10/2022 | | @ | ChC | W | Jimenez,E | 3 | 2 | | 21 | 17 | .553 | 5-5 | W1 | 38 |
| 5/11/2022 | | @ | ChC | W | Turner,J | 6 | 0 | | 22 | 17 | .564 | 5-5 | W2 | 39 |
| 5/12/2022 | | @ | ChC | W | Posey | 9 | 0 | | 23 | 17 | .575 | 5-5 | W3 | 40 |
| 5/23/2022 | | | Mtl | W | Albies | 1 | 0 | | 24 | 17 | .585 | 5-5 | W4 | 41 |
| 5/23/2022 | | @ | Oak | L | | 3 | 7 | | 24 | 18 | .571 | 5-5 | L1 | 42 |
| 5/24/2022 | | | Mtl | W | Turner,J | 8 | 5 | | 25 | 18 | .581 | 6-4 | W1 | 43 |
| 5/24/2022 | | @ | Oak | L | | 1 | 2 | | 25 | 19 | .568 | 6-4 | L1 | 44 |
| 5/25/2022 | | | Mtl | W | Pujols | 6 | 4 | | 26 | 19 | .578 | 7-3 | W1 | 45 |
| 5/25/2022 | | @ | Oak | W | Gamel | 7 | 2 | | 27 | 19 | .587 | 7-3 | W2 | 46 |
| 5/26/2022 | | | Mtl | L | | 4 | 7 | | 27 | 20 | .574 | 7-3 | L1 | 47 |
| 5/26/2022 | | @ | Oak | W | Ohtani | 4 | 2 | | 28 | 20 | .583 | 7-3 | W1 | 48 |
| 5/27/2022 | | | Det | W | Harper,B | 15 | 3 | | 29 | 20 | .592 | 7-3 | W2 | 49 |
| 5/27/2022 | | @ | Min | L | | 1 | 2 | | 29 | 21 | .580 | 6-4 | L1 | 50 |
| 5/28/2022 | | | Det | L | | 2 | 8 | | 29 | 22 | .569 | 5-5 | L2 | 51 |
| 5/28/2022 | | @ | Min | W | Turner,J | 3 | 2 | | 30 | 22 | .577 | 6-4 | W1 | 52 |
| 5/29/2022 | | | Det | W | Pujols | 12 | 4 | | 31 | 22 | .585 | 6-4 | W2 | 53 |
| 5/29/2022 | | @ | Min | W | Castellanos,N | 11 | 2 | | 32 | 22 | .593 | 7-3 | W3 | 54 |
| 5/31/2022 | | @ | Bal | W | Turner,J | 5 | 2 | | 33 | 22 | .600 | 7-3 | W4 | 55 |
| 5/31/2022 | | | Tex | W | Ohtani | 4 | 3 | | 34 | 22 | .607 | 7-3 | W5 | 56 |
| 6/1/2022 | | @ | Bal | W | Albies | 6 | 2 | | 35 | 22 | .614 | 8-2 | W6 | 57 |
| 6/1/2022 | | | Tex | W | Ohtani | 10 | 1 | | 36 | 22 | .621 | 8-2 | W7 | 58 |
| 6/2/2022 | | @ | Bal | W | Turner,J | 15 | 5 | | 37 | 22 | .627 | 8-2 | W8 | 59 |
| 6/2/2022 | | | Tex | W | Gamel | 2 | 1 | | 38 | 22 | .633 | 9-1 | W9 | 60 |
| 6/3/2022 | | @ | Bal | W | Ohtani | 8 | 2 | | 39 | 22 | .639 | 10-0 | W10 | 61 |
| 6/3/2022 | | | Tex | W | Castellanos,N | 4 | 2 | | 40 | 22 | .645 | 10-0 | W11 | 62 |
| 6/7/2022 | | | Ari | W | Castellanos,N | 6 | 4 | | 41 | 22 | .651 | 10-0 | W12 | 63 |
| 6/8/2022 | | | Ari | W | Castellanos,N | 10 | 2 | | 42 | 22 | .656 | 10-0 | W13 | 64 |
| 6/9/2022 | | | Ari | W | | 1 | 0 | | 43 | 22 | .662 | 10-0 | W14 | 65 |
| 6/10/2022 | | | SDP | W | Harper,B | 4 | 1 | | 44 | 22 | .667 | 10-0 | W15 | 66 |
| 6/11/2022 | | | SDP | L | | 1 | 8 | | 44 | 23 | .657 | 9-1 | L1 | 67 |
| 6/12/2022 | | | SDP | W | Diaz,L | 11 | 4 | | 45 | 23 | .662 | 9-1 | W1 | 68 |
| 6/14/2022 | | | Col | W | Gamel | 9 | 5 | | 46 | 23 | .667 | 9-1 | W2 | 69 |
| 6/15/2022 | | | Col | W | Gamel | 11 | 6 | | 47 | 23 | .671 | 9-1 | W3 | 70 |
| 6/16/2022 | | | Col | W | Gamel | 13 | 3 | | 48 | 23 | .676 | 9-1 | W4 | 71 |
| 6/17/2022 | | @ | StL | W | Harper,B | 10 | 5 | | 49 | 23 | .681 | 9-1 | W5 | 72 |
| 6/18/2022 | | @ | StL | W | Gamel | 4 | 2 | | 50 | 23 | .685 | 9-1 | W6 | 73 |
| 6/19/2022 | | @ | StL | L | | 0 | 4 | | 50 | 24 | .676 | 8-2 | L1 | 74 |
| 6/21/2022 | | @ | Cin | W | Posey | 11 | 3 | | 51 | 24 | .680 | 8-2 | W1 | 75 |
| 6/22/2022 | | @ | Cin | W | Harper,B | 6 | 4 | | 52 | 24 | .684 | 8-2 | W2 | 76 |
| 6/23/2022 | | @ | Cin | L | | 3 | 6 | | 52 | 25 | .675 | 8-2 | L1 | 77 |
| 6/24/2022 | | @ | Mil | L | | 5 | 14 | | 52 | 26 | .667 | 7-3 | L2 | 78 |
| 6/25/2022 | | @ | Mil | L | | 1 | 3 | | 52 | 27 | .658 | 6-4 | L3 | 79 |
| 6/26/2022 | | @ | Mil | W | Ohtani | 9 | 3 | | 53 | 27 | .663 | 6-4 | W1 | 80 |
| 7/14/2022 | | | Bos | W | Pujols | 2 | 1 | | 54 | 27 | .667 | 6-4 | W2 | 81 |
| 7/14/2022 | | @ | Sea | W | Harper,B | 10 | 1 | | 55 | 27 | .671 | 6-4 | W3 | 82 |
| 7/15/2022 | | | Bos | W | Castellanos,N | 7 | 5 | | 56 | 27 | .675 | 6-4 | W4 | 83 |
| 7/15/2022 | | @ | Sea | W | Castellanos,N | 10 | 1 | | 57 | 27 | .679 | 7-3 | W5 | 84 |
| 7/16/2022 | | | Bos | W | Ohtani | 6 | 4 | | 58 | 27 | .682 | 7-3 | W6 | 85 |
| 7/16/2022 | | @ | Sea | L | | 2 | 3 | | 58 | 28 | .674 | 6-4 | L1 | 86 |
| 7/17/2022 | | | Bos | L | | 1 | 6 | | 58 | 29 | .667 | 6-4 | L2 | 87 |
| 7/17/2022 | | @ | Sea | W | Turner,J | 4 | 3 | | 59 | 29 | .670 | 7-3 | W1 | 88 |
| 7/18/2022 | | | Min | L | | 6 | 9 | | 59 | 30 | .663 | 7-3 | L1 | 89 |
| 7/18/2022 | | @ | Det | W | Ohtani | 5 | 2 | | 60 | 30 | .667 | 7-3 | W1 | 90 |
| 7/19/2022 | | | Min | W | Castellanos,N | 7 | 2 | | 61 | 30 | .670 | 7-3 | W2 | 91 |
| 7/19/2022 | | @ | Det | W | Gamel | 10 | 6 | | 62 | 30 | .674 | 7-3 | W3 | 92 |
| 7/20/2022 | | | Min | L | | 1 | 2 | | 62 | 31 | .667 | 6-4 | L1 | 93 |
| 7/20/2022 | | @ | Det | W | Castellanos,N | 4 | 3 | | 63 | 31 | .670 | 6-4 | W1 | 94 |
| 7/22/2022 | | @ | Bos | W | Jimenez,E | 11 | 6 | | 64 | 31 | .674 | 6-4 | W2 | 95 |
| 7/22/2022 | | | KCR | W | Posey | 8 | 3 | | 65 | 31 | .677 | 7-3 | W3 | 96 |
| 7/23/2022 | | @ | Bos | L | | 3 | 4 | | 65 | 32 | .670 | 7-3 | L1 | 97 |
| 7/23/2022 | | | KCR | W | Posey | 7 | 1 | | 66 | 32 | .673 | 7-3 | W1 | 98 |
| 7/24/2022 | | @ | Bos | W | Posey | 5 | 2 | | 67 | 32 | .677 | 8-2 | W2 | 99 |
| 7/24/2022 | | | KCR | L | | 1 | 4 | | 67 | 33 | .670 | 7-3 | L1 | 100 |
| 7/25/2022 | | @ | Bos | L | | 4 | 5 | | 67 | 34 | .663 | 6-4 | L2 | 101 |
| 7/25/2022 | | | KCR | L | | 1 | 4 | | 67 | 35 | .657 | 5-5 | L3 | 102 |
| 8/5/2022 | | | Tor | W | Posey | 4 | 3 | | 68 | 35 | .660 | 6-4 | W1 | 103 |
| 8/5/2022 | | @ | Cle | W | Ohtani | 17 | 6 | | 69 | 35 | .663 | 6-4 | W2 | 104 |
| 8/6/2022 | | | Tor | W | Posey | 9 | 7 | | 70 | 35 | .667 | 6-4 | W3 | 105 |
| 8/6/2022 | | @ | Cle | L | | 3 | 9 | | 70 | 36 | .660 | 5-5 | L1 | 106 |
| 8/7/2022 | | | Tor | W | Posey | 3 | 1 | | 71 | 36 | .664 | 6-4 | W1 | 107 |
| 8/7/2022 | | @ | Cle | L | | 2 | 4 | | 71 | 37 | .657 | 5-5 | L1 | 108 |
| 8/8/2022 | | @ | Tor | W | | 7 | 3 | | 72 | 37 | .661 | 5-5 | W1 | 109 |
| 8/8/2022 | | | Cle | W | Castellanos,N | 7 | 5 | | 73 | 37 | .664 | 6-4 | W2 | 110 |
| 8/9/2022 | | @ | Tor | L | | 5 | 8 | | 73 | 38 | .658 | 6-4 | L1 | 111 |
| 8/9/2022 | | | Cle | W | Ohtani | 9 | 1 | | 74 | 38 | .661 | 7-3 | W1 | 112 |
| 8/10/2022 | | @ | Tor | L | | 3 | 5 | | 74 | 39 | .655 | 6-4 | L1 | 113 |
| 8/10/2022 | | | Cle | W | Gallagher | 6 | 2 | | 75 | 39 | .658 | 6-4 | W1 | 114 |
| 8/12/2022 | | @ | NYY | L | | 1 | 6 | | 75 | 40 | .652 | 5-5 | L1 | 115 |
| 8/12/2022 | | | LAA | W | Ohtani | 12 | 1 | | 76 | 40 | .655 | 6-4 | W1 | 116 |
| 8/13/2022 | | @ | NYY | L | | 3 | 7 | | 76 | 41 | .650 | 5-5 | L1 | 117 |
| 8/13/2022 | | | LAA | L | | 1 | 3 | | 76 | 42 | .644 | 5-5 | L2 | 118 |
| 8/14/2022 | | @ | NYY | L | | 1 | 2 | | 76 | 43 | .639 | 4-6 | L3 | 119 |
| 8/14/2022 | | | LAA | W | | 5 | 4 | | 77 | 43 | .642 | 4-6 | W1 | 120 |
| 8/15/2022 | | @ | NYY | W | Ohtani | 7 | 4 | | 78 | 43 | .645 | 5-5 | W2 | 121 |
| 8/15/2022 | | | LAA | W | Ohtani | 6 | 4 | | 79 | 43 | .648 | 5-5 | W3 | 122 |
| 8/22/2022 | | | Sea | W | Castellanos,N | 5 | 3 | | 80 | 43 | .650 | 6-4 | W4 | 123 |
| 8/22/2022 | | @ | Was | L | | 1 | 3 | | 80 | 44 | .645 | 5-5 | L1 | 124 |
| 8/23/2022 | | | Sea | W | Ohtani | 14 | 4 | | 81 | 44 | .648 | 6-4 | W1 | 125 |
| 8/23/2022 | | @ | Was | L | | 3 | 4 | | 81 | 45 | .643 | 5-5 | L1 | 126 |
| 8/24/2022 | | | Sea | W | Albies | 7 | 3 | | 82 | 45 | .646 | 6-4 | W1 | 127 |
| 8/24/2022 | | @ | Was | L | | 3 | 7 | | 82 | 46 | .641 | 6-4 | L1 | 128 |
| 8/25/2022 | | | Sea | L | | 4 | 7 | | 82 | 47 | .636 | 6-4 | L2 | 129 |
| 8/25/2022 | | @ | Was | L | | 6 | 7 | | 82 | 48 | .631 | 5-5 | L3 | 130 |
| 8/26/2022 | | @ | Mtl | W | Harper,B | 4 | 1 | | 83 | 48 | .634 | 5-5 | W1 | 131 |
| 8/26/2022 | | | Oak | W | Gamel | 6 | 5 | | 84 | 48 | .636 | 5-5 | W2 | 132 |
| 8/27/2022 | | @ | Mtl | W | Turner,J | 9 | 0 | | 85 | 48 | .639 | 5-5 | W3 | 133 |
| 8/27/2022 | | | Oak | W | Pujols | 4 | 3 | | 86 | 48 | .642 | 6-4 | W4 | 134 |
| 8/28/2022 | | @ | Mtl | L | | 2 | 7 | | 86 | 49 | .637 | 5-5 | L1 | 135 |
| 8/28/2022 | | | Oak | L | | 4 | 10 | | 86 | 50 | .632 | 5-5 | L2 | 136 |
| 8/29/2022 | | @ | Mtl | L | | 3 | 4 | | 86 | 51 | .628 | 4-6 | L3 | 137 |
| 8/29/2022 | | | Oak | L | | 5 | 9 | | 86 | 52 | .623 | 4-6 | L4 | 138 |
| 9/6/2022 | | | Det | W | Jimenez,E | 11 | 3 | | 87 | 52 | .626 | 5-5 | W1 | 139 |
| 9/6/2022 | | @ | Min | L | | 3 | 5 | | 87 | 53 | .621 | 5-5 | L1 | 140 |
| 9/7/2022 | | | Det | W | Ohtani | 4 | 2 | | 88 | 53 | .624 | 5-5 | W1 | 141 |
| 9/7/2022 | | @ | Min | L | | 1 | 5 | | 88 | 54 | .620 | 4-6 | L1 | 142 |
| 9/8/2022 | | | Det | W | Albies | 10 | 4 | | 89 | 54 | .622 | 4-6 | W1 | 143 |
| 9/8/2022 | | @ | Min | L | | 1 | 7 | | 89 | 55 | .618 | 3-7 | L1 | 144 |
| 9/9/2022 | | | NYY | W | Albies | 9 | 0 | | 90 | 55 | .621 | 4-6 | W1 | 145 |
| 9/9/2022 | | @ | KCR | L | | 0 | 9 | | 90 | 56 | .616 | 4-6 | L1 | 146 |
| 9/10/2022 | | | NYY | W | Harper,B | 15 | 5 | | 91 | 56 | .619 | 5-5 | W1 | 147 |
| 9/10/2022 | | @ | KCR | L | | 0 | 7 | | 91 | 57 | .615 | 5-5 | L1 | 148 |
| 9/11/2022 | | | NYY | W | Posey | 16 | 5 | | 92 | 57 | .617 | 5-5 | W1 | 149 |
| 9/11/2022 | | @ | KCR | W | Posey | 4 | 3 | | 93 | 57 | .620 | 6-4 | W2 | 150 |
| 9/12/2022 | | | NYY | W | Albies | 7 | 2 | | 94 | 57 | .623 | 6-4 | W3 | 151 |
| 9/12/2022 | | @ | KCR | W | Gamel | 12 | 7 | | 95 | 57 | .625 | 7-3 | W4 | 152 |
| 9/23/2022 | | | Min | L | | 4 | 6 | | 95 | 58 | .621 | 6-4 | L1 | 153 |
| 9/23/2022 | | @ | Det | L | | 2 | 3 | | 95 | 59 | .617 | 6-4 | L2 | 154 |
| 9/24/2022 | | | Min | W | | 3 | 0 | | 96 | 59 | .619 | 6-4 | W1 | 155 |
| 9/24/2022 | | @ | Det | W | Jimenez,E | 17 | 5 | | 97 | 59 | .622 | 7-3 | W2 | 156 |
| 9/25/2022 | | | Min | L | | 3 | 4 | | 97 | 60 | .618 | 6-4 | L1 | 157 |
| 9/25/2022 | | @ | Det | W | Harper,B | 2 | 1 | | 98 | 60 | .620 | 7-3 | W1 | 158 |
| 9/26/2022 | | | Det | W | Ohtani | 11 | 7 | | 99 | 60 | .623 | 7-3 | W2 | 159 |
| 9/26/2022 | | @ | Min | L | | 2 | 4 | | 99 | 61 | .619 | 6-4 | L1 | 160 |
| 9/27/2022 | | | Det | W | Pujols | 2 | 0 | | 100 | 61 | .621 | 6-4 | W1 | 161 |
| 9/27/2022 | | @ | Min | L | | 9 | 12 | | 100 | 62 | .617 | 5-5 | L1 | 162 |