Team game results -- 2021 New York Yankees
Regular season
| Primary |
| Date | # | | Opp | | Score | Inn | Starter | T | Decision | Save | Versus | T |
| 4/8/2021 | | |  LAA | L | 3-4 | | Flaherty,J | R | Flaherty,J | | Junis | R |
| 4/8/2021 | | @ |  Cle | L | 3-5 | | Flaherty,J | R | Flaherty,J | | Verlander | R |
| 4/9/2021 | | | LAA | L | 5-6 | 12 | Bundy | R | Hader | | Williams,Tr | R |
| 4/9/2021 | | @ | Cle | L | 5-9 | | Bundy | R | Melancon | | Hendricks | R |
| 4/10/2021 | | | LAA | L | 0-1 | | Minor | L | Minor | | Keuchel | L |
| 4/10/2021 | | @ | Cle | L | 5-6 | 13 | Minor | L | Cessa | | Keller, Brad | R |
| 4/11/2021 | | | LAA | W | 9-8 | | Lamet | R | Lamet | | Pineda | R |
| 4/11/2021 | | @ | Cle | W | 7-3 | | Lamet | R | Lamet | | Keller, Mitch | R |
| 4/12/2021 | | |  Mtl | W | 5-1 | | Toussaint | R | Toussaint | Hader | James,J | R |
| 4/12/2021 | | @ |  Was | L | 3-6 | | Toussaint | R | Toussaint | | Burnes | R |
| 4/13/2021 | | | Mtl | W | 6-5 | | Flaherty,J | R | Castillo,Jo | Hader | Bumgarner | L |
| 4/13/2021 | | @ | Was | L | 3-9 | | Flaherty,J | R | Flaherty,J | | Eflin | R |
| 4/14/2021 | | | Mtl | L | 3-9 | | Bundy | R | Bundy | | Lopez,P | R |
| 4/14/2021 | | @ | Was | W | 9-7 | | Bundy | R | Bundy | Hader | Barria | R |
| 4/16/2021 | | @ |  Bal | W | 6-1 | | Minor | L | Minor | | Roark | R |
| 4/16/2021 | | |  Bos | W | 3-2 | | Minor | L | Minor | Hader | Margevicius | L |
| 4/17/2021 | | @ | Bal | L | 5-9 | | Lamet | R | Lamet | | Foltynewicz | R |
| 4/17/2021 | | | Bos | L | 3-8 | | Lamet | R | Lamet | | Clarke | R |
| 4/18/2021 | | @ | Bal | L | 0-6 | | Flaherty,J | R | Flaherty,J | | Hill,R | L |
| 4/18/2021 | | | Bos | L | 3-5 | | Flaherty,J | R | Flaherty,J | | Rodriguez,E | L |
| 4/23/2021 | | |  SFG | W | 3-1 | | Bundy | R | Bundy | Hader | Lopez,Re | R |
| 4/24/2021 | | | SFG | W | 7-1 | | Minor | L | Minor | | Crowe | R |
| 4/25/2021 | | | SFG | W | 10-7 | | Lamet | R | Cessa | Hader | Kay | L |
| 4/27/2021 | | |  SDP | L | 2-8 | | Flaherty,J | R | Flaherty,J | | Nola,Aa | R |
| 4/28/2021 | | | SDP | L | 6-7 | | Javier | R | Javier | | Maeda | R |
| 4/29/2021 | | | SDP | W | 6-4 | | Bundy | R | Bundy | Hader | Scherzer | R |
| 5/3/2021 | | |  ChW | L | 2-3 | | Bundy | R | Bundy | | Lester,Jon | L |
| 5/3/2021 | | @ |  KCR | W | 3-1 | | Bundy | R | Bundy | Hader | Quintana,J | L |
| 5/4/2021 | | | ChW | L | 0-4 | | Minor | L | Minor | | Wood,A | L |
| 5/4/2021 | | @ | KCR | L | 2-3 | 10 | Minor | L | Hader | | Wilson,Bry | R |
| 5/5/2021 | | | ChW | W | 6-3 | | Lamet | R | Green,C | Hader | Porcello | R |
| 5/5/2021 | | @ | KCR | W | 3-0 | | Flaherty,J | R | Flaherty,J | | Fried | L |
| 5/6/2021 | | | ChW | W | 5-2 | | Javier | R | Javier | Hader | Bassitt | R |
| 5/6/2021 | | @ | KCR | W | 6-1 | | Lamet | R | Lamet | | Hudson,Dak | R |
| 5/7/2021 | | @ |  ChC | L | 2-5 | | Bundy | R | Cessa | | Mikolas | R |
| 5/8/2021 | | @ | ChC | L | 5-6 | | Minor | L | Minor | | Norris,D | L |
| 5/9/2021 | | @ | ChC | L | 2-5 | | Javier | R | Javier | | Pearson | R |
| 5/11/2021 | | @ |  Cin | L | 2-11 | | Flaherty,J | R | Flaherty,J | | Fedde | R |
| 5/12/2021 | | @ | Cin | L | 1-2 | | Lamet | R | Green,C | | Bauer | R |
| 5/13/2021 | | @ | Cin | L | 4-5 | 10 | Bundy | R | Melancon | | Peralta,F | R |
| 5/24/2021 | | |  Det | W | 5-4 | | Minor | L | Hader | | Fulmer,M | R |
| 5/24/2021 | | @ |  Oak | L | 1-10 | | Minor | L | Minor | | Walker,T | R |
| 5/25/2021 | | | Det | L | 5-6 | | Toussaint | R | Hader | | Sheffield,Ju | L |
| 5/25/2021 | | @ | Oak | W | 4-0 | | Toussaint | R | Toussaint | | Eickhoff | R |
| 5/26/2021 | | | Det | L | 6-12 | | Flaherty,J | R | Flaherty,J | | Happ,J.A. | L |
| 5/26/2021 | | @ | Oak | L | 5-6 | 13 | Flaherty,J | R | Hader | | Cole,G | R |
| 5/27/2021 | | | Det | L | 4-9 | | Bundy | R | Bundy | | Duffy,D | L |
| 5/27/2021 | | @ | Oak | L | 0-9 | | Bundy | R | Bundy | | Wainwright | R |
| 5/28/2021 | | | Was | W | 6-0 | | Javier | R | Javier | Hader | Burnes | R |
| 5/28/2021 | | @ | Mtl | L | 2-5 | | Javier | R | Javier | | Fleming,J | L |
| 5/29/2021 | | | Was | W | 5-4 | | Minor | L | Minor | Sobotka | McKay,B | L |
| 5/29/2021 | | @ | Mtl | L | 2-5 | | Minor | L | Minor | | Yarbrough | L |
| 5/30/2021 | | | Was | L | 4-5 | 10 | Toussaint | R | Green,C | | Pivetta | R |
| 5/30/2021 | | @ | Mtl | L | 6-7 | 12 | Toussaint | R | Minter | | Dobnak | R |
| 6/1/2021 | | |  Tor | W | 3-2 | | Flaherty,J | R | Hader | | Freeland | L |
| 6/1/2021 | | @ |  Sea | L | 1-2 | | Flaherty,J | R | Flaherty,J | | Paxton | L |
| 6/2/2021 | | | Tor | W | 3-2 | 10 | Bundy | R | Sobotka | | Plutko | R |
| 6/2/2021 | | @ | Sea | W | 5-2 | | Bundy | R | Bundy | Minter | Odorizzi | R |
| 6/3/2021 | | | Tor | W | 3-1 | | Javier | R | Cessa | Sobotka | Lambert,P | R |
| 6/3/2021 | | @ | Sea | W | 5-4 | | Javier | R | Cessa | Baez,P | Samardzija | R |
| 6/4/2021 | | | Tor | L | 0-2 | | Minor | L | Minor | | Freeland | L |
| 6/4/2021 | | @ | Sea | W | 4-1 | | Minor | L | Minor | Hader | Gonzales | L |
| 6/8/2021 | | |  Ari | W | 9-4 | | Lamet | R | Cessa | Green,C | Mahle | R |
| 6/9/2021 | | | Ari | W | 6-5 | 12 | Flaherty,J | R | Melancon | | Canning | R |
| 6/10/2021 | | | Ari | W | 6-4 | | Bundy | R | Minter | | Strasburg | R |
| 6/11/2021 | | |  Col | W | 7-5 | | Minor | L | Minor | | Morton | R |
| 6/12/2021 | | | Col | L | 2-8 | | Ross,T | R | Ross,T | | Ponce De Leon | R |
| 6/13/2021 | | | Col | W | 4-3 | 11 | Lamet | R | Baez,P | | Lockett | R |
| 6/15/2021 | | |  LAD | W | 8-6 | | Flaherty,J | R | Flaherty,J | Hader | Sanchez,S | R |
| 6/16/2021 | | | LAD | W | 4-3 | | Bundy | R | Bundy | Hader | Berrios | R |
| 6/17/2021 | | | LAD | W | 5-2 | | Minor | L | Minor | Minter | Kremer | R |
| 6/18/2021 | | @ |  Mil | L | 1-2 | | Lamet | R | Lamet | | Darvish | R |
| 6/19/2021 | | @ | Mil | L | 8-10 | | Flaherty,J | R | Baez,P | | Kopech | R |
| 6/20/2021 | | @ | Mil | W | 4-2 | | Bundy | R | Bundy | Hader | Kelly,M | R |
| 6/22/2021 | | @ |  Hou | L | 3-4 | 11 | Minor | L | Green,C | | Glasnow | R |
| 6/23/2021 | | @ | Hou | L | 4-6 | | Ross,T | R | Ross,T | | deGrom | R |
| 6/24/2021 | | @ | Hou | W | 8-6 | | Lamet | R | Cessa | Hader | Howard,Sp | R |
| 6/25/2021 | | @ |  StL | W | 3-0 | | Flaherty,J | R | Flaherty,J | | Bedrosian | R |
| 6/26/2021 | | @ | StL | W | 12-2 | | Bundy | R | Bundy | | Skubal | L |
| 6/27/2021 | | @ | StL | W | 9-7 | | Minor | L | Minor | Hader | Heaney | L |
| 7/15/2021 | | | Oak | L | 5-7 | | Flaherty,J | R | Flaherty,J | | Abreu,B | R |
| 7/15/2021 | | @ | Det | W | 9-7 | 15 | Flaherty,J | R | Green,C | Cessa | Salazar | R |
| 7/16/2021 | | | Oak | L | 4-7 | | Whitley,F | R | Castillo,Jo | | Walker,T | R |
| 7/16/2021 | | @ | Det | L | 0-7 | | Whitley,F | R | Whitley,F | | Duffy,D | L |
| 7/17/2021 | | | Oak | W | 8-3 | | Lamet | R | Lamet | | Hamels | L |
| 7/17/2021 | | @ | Det | W | 8-0 | | Bundy | R | Bundy | | Sheffield,Ju | L |
| 7/18/2021 | | | Oak | W | 6-0 | | Minor | L | Minor | | Wainwright | R |
| 7/18/2021 | | @ | Det | W | 6-2 | | Lamet | R | Lamet | | Webb,L | R |
| 7/19/2021 | | @ | Bos | L | 2-3 | | Minor | L | Minor | | Pena,Fe | R |
| 7/19/2021 | | | Bal | L | 4-5 | | Bundy | R | Bundy | | German,D | R |
| 7/20/2021 | | @ | Bos | L | 2-6 | | Flaherty,J | R | Flaherty,J | | Rodriguez,E | L |
| 7/20/2021 | | | Bal | W | 3-1 | | Flaherty,J | R | Flaherty,J | | Yamamoto | R |
| 7/21/2021 | | @ | Bos | L | 2-5 | | Whitley,F | R | Whitley,F | | Blach | L |
| 7/21/2021 | | | Bal | L | 1-5 | | Whitley,F | R | Whitley,F | | Montgomery,J | L |
| 7/23/2021 | | | Sea | L | 2-8 | | Minor | L | Minor | | Samardzija | R |
| 7/23/2021 | | @ | Tor | L | 12-14 | | Bundy | R | Bundy | | Smyly | L |
| 7/24/2021 | | | Sea | L | 1-3 | | Lamet | R | Lamet | | Leake | R |
| 7/24/2021 | | @ | Tor | L | 2-4 | | Lamet | R | Green,C | | Reid-Foley | R |
| 7/25/2021 | | | Sea | W | 4-3 | | Flaherty,J | R | Hader | | Dunn,J | R |
| 7/25/2021 | | @ | Tor | L | 4-7 | | Minor | L | Minor | | Lambert,P | R |
| 7/26/2021 | | | Sea | W | 10-2 | | Bundy | R | Bundy | | Gonzales | L |
| 7/26/2021 | | @ | Tor | W | 13-3 | | Flaherty,J | R | Flaherty,J | | Freeland | L |
| 8/6/2021 | | @ | Bal | W | 5-4 | | Whitley,F | R | Whitley,F | Hader | Teheran | R |
| 8/6/2021 | | | Bos | L | 2-4 | | Whitley,F | R | Whitley,F | | Clarke | R |
| 8/7/2021 | | @ | Bal | W | 13-1 | | Toussaint | R | Toussaint | | Yamamoto | R |
| 8/7/2021 | | | Bos | W | 16-8 | | Toussaint | R | Toussaint | Castillo,Jo | Romano,S | R |
| 8/8/2021 | | @ | Bal | W | 2-1 | | Flaherty,J | R | Flaherty,J | Hader | Montgomery,J | L |
| 8/8/2021 | | | Bos | W | 6-5 | | Flaherty,J | R | Hader | | Smeltzer | L |
| 8/9/2021 | | | Mtl | W | 10-5 | | Lamet | R | Floro | | Anderson,Bre | L |
| 8/9/2021 | | @ | Was | W | 3-1 | | Lamet | R | Floro | Baez,P | Kuhl | R |
| 8/10/2021 | | | Mtl | L | 1-5 | | Javier | R | Javier | | Dobnak | R |
| 8/10/2021 | | @ | Was | L | 7-8 | | Javier | R | Hader | | Pivetta | R |
| 8/11/2021 | | | Mtl | W | 7-3 | | Whitley,F | R | Whitley,F | | Lopez,P | R |
| 8/11/2021 | | @ | Was | L | 1-4 | | Whitley,F | R | Whitley,F | | McKay,B | L |
| 8/13/2021 | | |  Min | L | 2-5 | | Flaherty,J | R | Flaherty,J | | Rasmussen | R |
| 8/13/2021 | | @ | LAA | W | 8-3 | | Flaherty,J | R | Flaherty,J | Floro | Akin | L |
| 8/14/2021 | | | Min | L | 0-2 | | Lamet | R | Lamet | | Ray,R | L |
| 8/14/2021 | | @ | LAA | L | 5-6 | 10 | Lamet | R | Melancon | | Hearn | L |
| 8/15/2021 | | | Min | L | 6-7 | 10 | Javier | R | Hader | | Urias,J | L |
| 8/15/2021 | | @ | LAA | W | 10-5 | | Javier | R | Javier | | Harvey,H | R |
| 8/16/2021 | | | Min | L | 3-6 | | Whitley,F | R | Whitley,F | | Paddack | R |
| 8/16/2021 | | @ | LAA | W | 6-5 | | Whitley,F | R | Whitley,F | Hader | Houck | R |
| 8/23/2021 | | | KCR | W | 6-3 | | Ross,T | R | Floro | Hader | Antone | R |
| 8/23/2021 | | @ | Min | L | 3-5 | | Ross,T | R | Ross,T | | Lauer | L |
| 8/24/2021 | | | KCR | W | 6-3 | | Alexander,TyJo | L | Alexander,TyJo | Hader | Hudson,Dak | R |
| 8/24/2021 | | @ | Min | L | 1-6 | | Toussaint | R | Toussaint | | Ray,R | L |
| 8/25/2021 | | | KCR | W | 8-3 | | Toussaint | R | Minter | | Davies | R |
| 8/25/2021 | | @ | Min | L | 3-5 | | Alexander,TyJo | L | Alexander,TyJo | | Turnbull | R |
| 8/26/2021 | | | KCR | W | 7-3 | | Javier | R | Javier | | Thornton | R |
| 8/26/2021 | | @ | Min | W | 11-5 | | Javier | R | Baez,P | | Gallen | R |
| 8/27/2021 | | |  Tex | W | 5-1 | | Flaherty,J | R | Flaherty,J | | Matz | L |
| 8/27/2021 | | @ | ChW | L | 3-7 | 10 | Flaherty,J | R | Melancon | | Giolito | R |
| 8/28/2021 | | | Tex | W | 7-1 | | Ross,T | R | Ross,T | | Hoffman | R |
| 8/28/2021 | | @ | ChW | L | 5-7 | | Ross,T | R | Castillo,Jo | | Puk | L |
| 8/29/2021 | | | Tex | W | 3-2 | 10 | Alexander,TyJo | L | Castillo,Jo | | Alzolay | R |
| 8/29/2021 | | @ | ChW | L | 3-6 | | Toussaint | R | Melancon | | Lester,Jon | L |
| 8/30/2021 | | | Tex | W | 2-0 | | Toussaint | R | Toussaint | Hader | Manaea | L |
| 8/30/2021 | | @ | ChW | L | 4-5 | | Alexander,TyJo | L | Hader | | Wood,A | L |
| 9/7/2021 | | | Was | W | 3-1 | | Whitley,F | R | Cessa | Hader | Duplantier | R |
| 9/7/2021 | | @ | Mtl | W | 10-8 | | Javier | R | Cisnero | Hader | Lopez,P | R |
| 9/8/2021 | | | Was | W | 10-5 | | Toussaint | R | Hernandez,Dar | | Kuhl | R |
| 9/8/2021 | | @ | Mtl | L | 5-9 | | Flaherty,J | R | Flaherty,J | | Bumgarner | L |
| 9/9/2021 | | | Was | W | 5-4 | | Javier | R | Castillo,Jo | | Luzardo | L |
| 9/9/2021 | | @ | Mtl | L | 5-6 | | Alexander,TyJo | L | Hader | | Strahm | L |
| 9/10/2021 | | | Cle | W | 2-1 | | Lamet | R | Lamet | Hader | Keller, Mitch | R |
| 9/10/2021 | | @ | Tex | W | 7-1 | | Toussaint | R | Cessa | | Oviedo | R |
| 9/11/2021 | | | Cle | L | 4-9 | | Flaherty,J | R | Flaherty,J | | Woodruff | R |
| 9/11/2021 | | @ | Tex | W | 8-4 | | Ross,T | R | Ross,T | Green,C | Alzolay | R |
| 9/12/2021 | | | Cle | W | 8-3 | | Whitley,F | R | Whitley,F | | Davidson,T | L |
| 9/12/2021 | | @ | Tex | W | 14-1 | | Javier | R | Cisnero | | Faedo | R |
| 9/13/2021 | | | Cle | L | 4-5 | 11 | Toussaint | R | Green,C | | Keller, Brad | R |
| 9/13/2021 | | @ | Tex | W | 8-6 | | Whitley,F | R | Whitley,F | Melancon | Hoffman | R |
| 9/24/2021 | | @ | Bos | L | 3-5 | | Javier | R | Javier | | Blach | L |
| 9/24/2021 | | | Bal | W | 3-2 | 14 | Javier | R | Castillo,Jo | | Dunning | R |
| 9/25/2021 | | @ | Bos | L | 3-5 | | Whitley,F | R | Whitley,F | | Pena,Fe | R |
| 9/25/2021 | | | Bal | W | 7-4 | | Whitley,F | R | Sobotka | Hader | Teheran | R |
| 9/26/2021 | | @ | Bos | W | 6-4 | | Toussaint | R | Toussaint | Hader | Clarke | R |
| 9/26/2021 | | | Bal | L | 2-6 | | Toussaint | R | Toussaint | | Roark | R |
| 9/27/2021 | | | Mtl | W | 4-2 | | Flaherty,J | R | Green,C | Hader | Bumgarner | L |
| 9/27/2021 | | @ | Mtl | L | 3-6 | | Flaherty,J | R | Flaherty,J | | Lopez,P | R |
| 9/28/2021 | | | Mtl | W | 7-2 | | Lamet | R | Lamet | Hader | Thorpe | L |
| 9/28/2021 | | @ | Mtl | L | 4-7 | | Lamet | R | Lamet | | Bumgarner | L |
| Other |
| Game information | | Cumulative |
| Date | # | | Opp | | GWRBI | RF | RA | | W | L | Pct | L10 | Strk | Gm# |
| 4/8/2021 | | | LAA | L | | 3 | 4 | | 0 | 1 | .000 | 0-1 | L1 | 1 |
| 4/8/2021 | | @ | Cle | L | | 3 | 5 | | 0 | 2 | .000 | 0-2 | L2 | 2 |
| 4/9/2021 | | | LAA | L | | 5 | 6 | | 0 | 3 | .000 | 0-3 | L3 | 3 |
| 4/9/2021 | | @ | Cle | L | | 5 | 9 | | 0 | 4 | .000 | 0-4 | L4 | 4 |
| 4/10/2021 | | | LAA | L | | 0 | 1 | | 0 | 5 | .000 | 0-5 | L5 | 5 |
| 4/10/2021 | | @ | Cle | L | | 5 | 6 | | 0 | 6 | .000 | 0-6 | L6 | 6 |
| 4/11/2021 | | | LAA | W | Garcia,Av | 9 | 8 | | 1 | 6 | .143 | 1-6 | W1 | 7 |
| 4/11/2021 | | @ | Cle | W | Santana,Da | 7 | 3 | | 2 | 6 | .250 | 2-6 | W2 | 8 |
| 4/12/2021 | | | Mtl | W | Seager,K | 5 | 1 | | 3 | 6 | .333 | 3-6 | W3 | 9 |
| 4/12/2021 | | @ | Was | L | | 3 | 6 | | 3 | 7 | .300 | 3-7 | L1 | 10 |
| 4/13/2021 | | | Mtl | W | Buxton | 6 | 5 | | 4 | 7 | .364 | 4-6 | W1 | 11 |
| 4/13/2021 | | @ | Was | L | | 3 | 9 | | 4 | 8 | .333 | 4-6 | L1 | 12 |
| 4/14/2021 | | | Mtl | L | | 3 | 9 | | 4 | 9 | .308 | 4-6 | L2 | 13 |
| 4/14/2021 | | @ | Was | W | Smith,Do | 9 | 7 | | 5 | 9 | .357 | 5-5 | W1 | 14 |
| 4/16/2021 | | @ | Bal | W | Seager,K | 6 | 1 | | 6 | 9 | .400 | 6-4 | W2 | 15 |
| 4/16/2021 | | | Bos | W | Candelario | 3 | 2 | | 7 | 9 | .438 | 7-3 | W3 | 16 |
| 4/17/2021 | | @ | Bal | L | | 5 | 9 | | 7 | 10 | .412 | 6-4 | L1 | 17 |
| 4/17/2021 | | | Bos | L | | 3 | 8 | | 7 | 11 | .389 | 5-5 | L2 | 18 |
| 4/18/2021 | | @ | Bal | L | | 0 | 6 | | 7 | 12 | .368 | 4-6 | L3 | 19 |
| 4/18/2021 | | | Bos | L | | 3 | 5 | | 7 | 13 | .350 | 4-6 | L4 | 20 |
| 4/23/2021 | | | SFG | W | Marte,K | 3 | 1 | | 8 | 13 | .381 | 4-6 | W1 | 21 |
| 4/24/2021 | | | SFG | W | Smith,Do | 7 | 1 | | 9 | 13 | .409 | 5-5 | W2 | 22 |
| 4/25/2021 | | | SFG | W | Seager,K | 10 | 7 | | 10 | 13 | .435 | 6-4 | W3 | 23 |
| 4/27/2021 | | | SDP | L | | 2 | 8 | | 10 | 14 | .417 | 5-5 | L1 | 24 |
| 4/28/2021 | | | SDP | L | | 6 | 7 | | 10 | 15 | .400 | 4-6 | L2 | 25 |
| 4/29/2021 | | | SDP | W | Piscotty | 6 | 4 | | 11 | 15 | .423 | 4-6 | W1 | 26 |
| 5/3/2021 | | | ChW | L | | 2 | 3 | | 11 | 16 | .407 | 4-6 | L1 | 27 |
| 5/3/2021 | | @ | KCR | W | Dubon | 3 | 1 | | 12 | 16 | .429 | 5-5 | W1 | 28 |
| 5/4/2021 | | | ChW | L | | 0 | 4 | | 12 | 17 | .414 | 5-5 | L1 | 29 |
| 5/4/2021 | | @ | KCR | L | | 2 | 3 | | 12 | 18 | .400 | 5-5 | L2 | 30 |
| 5/5/2021 | | | ChW | W | Santana,Da | 6 | 3 | | 13 | 18 | .419 | 5-5 | W1 | 31 |
| 5/5/2021 | | @ | KCR | W | Garcia,Av | 3 | 0 | | 14 | 18 | .438 | 5-5 | W2 | 32 |
| 5/6/2021 | | | ChW | W | Odor | 5 | 2 | | 15 | 18 | .455 | 5-5 | W3 | 33 |
| 5/6/2021 | | @ | KCR | W | Murphy,T | 6 | 1 | | 16 | 18 | .471 | 6-4 | W4 | 34 |
| 5/7/2021 | | @ | ChC | L | | 2 | 5 | | 16 | 19 | .457 | 6-4 | L1 | 35 |
| 5/8/2021 | | @ | ChC | L | | 5 | 6 | | 16 | 20 | .444 | 5-5 | L2 | 36 |
| 5/9/2021 | | @ | ChC | L | | 2 | 5 | | 16 | 21 | .432 | 5-5 | L3 | 37 |
| 5/11/2021 | | @ | Cin | L | | 2 | 11 | | 16 | 22 | .421 | 4-6 | L4 | 38 |
| 5/12/2021 | | @ | Cin | L | | 1 | 2 | | 16 | 23 | .410 | 4-6 | L5 | 39 |
| 5/13/2021 | | @ | Cin | L | | 4 | 5 | | 16 | 24 | .400 | 4-6 | L6 | 40 |
| 5/24/2021 | | | Det | W | Ford | 5 | 4 | | 17 | 24 | .415 | 4-6 | W1 | 41 |
| 5/24/2021 | | @ | Oak | L | | 1 | 10 | | 17 | 25 | .405 | 3-7 | L1 | 42 |
| 5/25/2021 | | | Det | L | | 5 | 6 | | 17 | 26 | .395 | 2-8 | L2 | 43 |
| 5/25/2021 | | @ | Oak | W | Santana,Da | 4 | 0 | | 18 | 26 | .409 | 2-8 | W1 | 44 |
| 5/26/2021 | | | Det | L | | 6 | 12 | | 18 | 27 | .400 | 2-8 | L1 | 45 |
| 5/26/2021 | | @ | Oak | L | | 5 | 6 | | 18 | 28 | .391 | 2-8 | L2 | 46 |
| 5/27/2021 | | | Det | L | | 4 | 9 | | 18 | 29 | .383 | 2-8 | L3 | 47 |
| 5/27/2021 | | @ | Oak | L | | 0 | 9 | | 18 | 30 | .375 | 2-8 | L4 | 48 |
| 5/28/2021 | | | Was | W | | 6 | 0 | | 19 | 30 | .388 | 3-7 | W1 | 49 |
| 5/28/2021 | | @ | Mtl | L | | 2 | 5 | | 19 | 31 | .380 | 3-7 | L1 | 50 |
| 5/29/2021 | | | Was | W | Murphy,T | 5 | 4 | | 20 | 31 | .392 | 3-7 | W1 | 51 |
| 5/29/2021 | | @ | Mtl | L | | 2 | 5 | | 20 | 32 | .385 | 3-7 | L1 | 52 |
| 5/30/2021 | | | Was | L | | 4 | 5 | | 20 | 33 | .377 | 3-7 | L2 | 53 |
| 5/30/2021 | | @ | Mtl | L | | 6 | 7 | | 20 | 34 | .370 | 2-8 | L3 | 54 |
| 6/1/2021 | | | Tor | W | Odor | 3 | 2 | | 21 | 34 | .382 | 3-7 | W1 | 55 |
| 6/1/2021 | | @ | Sea | L | | 1 | 2 | | 21 | 35 | .375 | 3-7 | L1 | 56 |
| 6/2/2021 | | | Tor | W | Cordero,F | 3 | 2 | | 22 | 35 | .386 | 4-6 | W1 | 57 |
| 6/2/2021 | | @ | Sea | W | Marte,K | 5 | 2 | | 23 | 35 | .397 | 5-5 | W2 | 58 |
| 6/3/2021 | | | Tor | W | Smith,Do | 3 | 1 | | 24 | 35 | .407 | 5-5 | W3 | 59 |
| 6/3/2021 | | @ | Sea | W | Buxton | 5 | 4 | | 25 | 35 | .417 | 6-4 | W4 | 60 |
| 6/4/2021 | | | Tor | L | | 0 | 2 | | 25 | 36 | .410 | 5-5 | L1 | 61 |
| 6/4/2021 | | @ | Sea | W | Santana,Da | 4 | 1 | | 26 | 36 | .419 | 6-4 | W1 | 62 |
| 6/8/2021 | | | Ari | W | Santana,Da | 9 | 4 | | 27 | 36 | .429 | 7-3 | W2 | 63 |
| 6/9/2021 | | | Ari | W | Dubon | 6 | 5 | | 28 | 36 | .438 | 8-2 | W3 | 64 |
| 6/10/2021 | | | Ari | W | Candelario | 6 | 4 | | 29 | 36 | .446 | 8-2 | W4 | 65 |
| 6/11/2021 | | | Col | W | Candelario | 7 | 5 | | 30 | 36 | .455 | 9-1 | W5 | 66 |
| 6/12/2021 | | | Col | L | | 2 | 8 | | 30 | 37 | .448 | 8-2 | L1 | 67 |
| 6/13/2021 | | | Col | W | Dubon | 4 | 3 | | 31 | 37 | .456 | 8-2 | W1 | 68 |
| 6/15/2021 | | | LAD | W | Ford | 8 | 6 | | 32 | 37 | .464 | 8-2 | W2 | 69 |
| 6/16/2021 | | | LAD | W | Seager,K | 4 | 3 | | 33 | 37 | .471 | 8-2 | W3 | 70 |
| 6/17/2021 | | | LAD | W | Candelario | 5 | 2 | | 34 | 37 | .479 | 9-1 | W4 | 71 |
| 6/18/2021 | | @ | Mil | L | | 1 | 2 | | 34 | 38 | .472 | 8-2 | L1 | 72 |
| 6/19/2021 | | @ | Mil | L | | 8 | 10 | | 34 | 39 | .466 | 7-3 | L2 | 73 |
| 6/20/2021 | | @ | Mil | W | Candelario | 4 | 2 | | 35 | 39 | .473 | 7-3 | W1 | 74 |
| 6/22/2021 | | @ | Hou | L | | 3 | 4 | | 35 | 40 | .467 | 6-4 | L1 | 75 |
| 6/23/2021 | | @ | Hou | L | | 4 | 6 | | 35 | 41 | .461 | 5-5 | L2 | 76 |
| 6/24/2021 | | @ | Hou | W | Ford | 8 | 6 | | 36 | 41 | .468 | 6-4 | W1 | 77 |
| 6/25/2021 | | @ | StL | W | Piscotty | 3 | 0 | | 37 | 41 | .474 | 6-4 | W2 | 78 |
| 6/26/2021 | | @ | StL | W | Piscotty | 12 | 2 | | 38 | 41 | .481 | 6-4 | W3 | 79 |
| 6/27/2021 | | @ | StL | W | Huff | 9 | 7 | | 39 | 41 | .488 | 6-4 | W4 | 80 |
| 7/15/2021 | | | Oak | L | | 5 | 7 | | 39 | 42 | .481 | 5-5 | L1 | 81 |
| 7/15/2021 | | @ | Det | W | Buxton | 9 | 7 | | 40 | 42 | .488 | 6-4 | W1 | 82 |
| 7/16/2021 | | | Oak | L | | 4 | 7 | | 40 | 43 | .482 | 6-4 | L1 | 83 |
| 7/16/2021 | | @ | Det | L | | 0 | 7 | | 40 | 44 | .476 | 5-5 | L2 | 84 |
| 7/17/2021 | | | Oak | W | | 8 | 3 | | 41 | 44 | .482 | 6-4 | W1 | 85 |
| 7/17/2021 | | @ | Det | W | Garcia,Av | 8 | 0 | | 42 | 44 | .488 | 7-3 | W2 | 86 |
| 7/18/2021 | | | Oak | W | Candelario | 6 | 0 | | 43 | 44 | .494 | 7-3 | W3 | 87 |
| 7/18/2021 | | @ | Det | W | Seager,K | 6 | 2 | | 44 | 44 | .500 | 7-3 | W4 | 88 |
| 7/19/2021 | | @ | Bos | L | | 2 | 3 | | 44 | 45 | .494 | 6-4 | L1 | 89 |
| 7/19/2021 | | | Bal | L | | 4 | 5 | | 44 | 46 | .489 | 5-5 | L2 | 90 |
| 7/20/2021 | | @ | Bos | L | | 2 | 6 | | 44 | 47 | .484 | 5-5 | L3 | 91 |
| 7/20/2021 | | | Bal | W | Sanchez,G | 3 | 1 | | 45 | 47 | .489 | 5-5 | W1 | 92 |
| 7/21/2021 | | @ | Bos | L | | 2 | 5 | | 45 | 48 | .484 | 5-5 | L1 | 93 |
| 7/21/2021 | | | Bal | L | | 1 | 5 | | 45 | 49 | .479 | 5-5 | L2 | 94 |
| 7/23/2021 | | | Sea | L | | 2 | 8 | | 45 | 50 | .474 | 4-6 | L3 | 95 |
| 7/23/2021 | | @ | Tor | L | | 12 | 14 | | 45 | 51 | .469 | 3-7 | L4 | 96 |
| 7/24/2021 | | | Sea | L | | 1 | 3 | | 45 | 52 | .464 | 2-8 | L5 | 97 |
| 7/24/2021 | | @ | Tor | L | | 2 | 4 | | 45 | 53 | .459 | 1-9 | L6 | 98 |
| 7/25/2021 | | | Sea | W | Smith,Do | 4 | 3 | | 46 | 53 | .465 | 2-8 | W1 | 99 |
| 7/25/2021 | | @ | Tor | L | | 4 | 7 | | 46 | 54 | .460 | 2-8 | L1 | 100 |
| 7/26/2021 | | | Sea | W | Marte,K | 10 | 2 | | 47 | 54 | .465 | 3-7 | W1 | 101 |
| 7/26/2021 | | @ | Tor | W | Candelario | 13 | 3 | | 48 | 54 | .471 | 3-7 | W2 | 102 |
| 8/6/2021 | | @ | Bal | W | Piscotty | 5 | 4 | | 49 | 54 | .476 | 4-6 | W3 | 103 |
| 8/6/2021 | | | Bos | L | | 2 | 4 | | 49 | 55 | .471 | 4-6 | L1 | 104 |
| 8/7/2021 | | @ | Bal | W | Smith,Do | 13 | 1 | | 50 | 55 | .476 | 5-5 | W1 | 105 |
| 8/7/2021 | | | Bos | W | Smith,Do | 16 | 8 | | 51 | 55 | .481 | 6-4 | W2 | 106 |
| 8/8/2021 | | @ | Bal | W | Garcia,Av | 2 | 1 | | 52 | 55 | .486 | 7-3 | W3 | 107 |
| 8/8/2021 | | | Bos | W | Seager,K | 6 | 5 | | 53 | 55 | .491 | 8-2 | W4 | 108 |
| 8/9/2021 | | | Mtl | W | Marte,K | 10 | 5 | | 54 | 55 | .495 | 8-2 | W5 | 109 |
| 8/9/2021 | | @ | Was | W | Ford | 3 | 1 | | 55 | 55 | .500 | 9-1 | W6 | 110 |
| 8/10/2021 | | | Mtl | L | | 1 | 5 | | 55 | 56 | .495 | 8-2 | L1 | 111 |
| 8/10/2021 | | @ | Was | L | | 7 | 8 | | 55 | 57 | .491 | 7-3 | L2 | 112 |
| 8/11/2021 | | | Mtl | W | Odor | 7 | 3 | | 56 | 57 | .496 | 7-3 | W1 | 113 |
| 8/11/2021 | | @ | Was | L | | 1 | 4 | | 56 | 58 | .491 | 7-3 | L1 | 114 |
| 8/13/2021 | | | Min | L | | 2 | 5 | | 56 | 59 | .487 | 6-4 | L2 | 115 |
| 8/13/2021 | | @ | LAA | W | | 8 | 3 | | 57 | 59 | .491 | 6-4 | W1 | 116 |
| 8/14/2021 | | | Min | L | | 0 | 2 | | 57 | 60 | .487 | 5-5 | L1 | 117 |
| 8/14/2021 | | @ | LAA | L | | 5 | 6 | | 57 | 61 | .483 | 4-6 | L2 | 118 |
| 8/15/2021 | | | Min | L | | 6 | 7 | | 57 | 62 | .479 | 3-7 | L3 | 119 |
| 8/15/2021 | | @ | LAA | W | Garcia,Av | 10 | 5 | | 58 | 62 | .483 | 3-7 | W1 | 120 |
| 8/16/2021 | | | Min | L | | 3 | 6 | | 58 | 63 | .479 | 3-7 | L1 | 121 |
| 8/16/2021 | | @ | LAA | W | Ford | 6 | 5 | | 59 | 63 | .484 | 4-6 | W1 | 122 |
| 8/23/2021 | | | KCR | W | Dubon | 6 | 3 | | 60 | 63 | .488 | 4-6 | W2 | 123 |
| 8/23/2021 | | @ | Min | L | | 3 | 5 | | 60 | 64 | .484 | 4-6 | L1 | 124 |
| 8/24/2021 | | | KCR | W | Murphy,T | 6 | 3 | | 61 | 64 | .488 | 5-5 | W1 | 125 |
| 8/24/2021 | | @ | Min | L | | 1 | 6 | | 61 | 65 | .484 | 4-6 | L1 | 126 |
| 8/25/2021 | | | KCR | W | Seager,K | 8 | 3 | | 62 | 65 | .488 | 5-5 | W1 | 127 |
| 8/25/2021 | | @ | Min | L | | 3 | 5 | | 62 | 66 | .484 | 5-5 | L1 | 128 |
| 8/26/2021 | | | KCR | W | Seager,K | 7 | 3 | | 63 | 66 | .488 | 6-4 | W1 | 129 |
| 8/26/2021 | | @ | Min | W | Wade,T | 11 | 5 | | 64 | 66 | .492 | 6-4 | W2 | 130 |
| 8/27/2021 | | | Tex | W | Quinn,R | 5 | 1 | | 65 | 66 | .496 | 7-3 | W3 | 131 |
| 8/27/2021 | | @ | ChW | L | | 3 | 7 | | 65 | 67 | .492 | 6-4 | L1 | 132 |
| 8/28/2021 | | | Tex | W | Candelario | 7 | 1 | | 66 | 67 | .496 | 6-4 | W1 | 133 |
| 8/28/2021 | | @ | ChW | L | | 5 | 7 | | 66 | 68 | .493 | 6-4 | L1 | 134 |
| 8/29/2021 | | | Tex | W | Candelario | 3 | 2 | | 67 | 68 | .496 | 6-4 | W1 | 135 |
| 8/29/2021 | | @ | ChW | L | | 3 | 6 | | 67 | 69 | .493 | 6-4 | L1 | 136 |
| 8/30/2021 | | | Tex | W | Sanchez,G | 2 | 0 | | 68 | 69 | .496 | 6-4 | W1 | 137 |
| 8/30/2021 | | @ | ChW | L | | 4 | 5 | | 68 | 70 | .493 | 6-4 | L1 | 138 |
| 9/7/2021 | | | Was | W | Santana,Da | 3 | 1 | | 69 | 70 | .496 | 6-4 | W1 | 139 |
| 9/7/2021 | | @ | Mtl | W | Seager,K | 10 | 8 | | 70 | 70 | .500 | 6-4 | W2 | 140 |
| 9/8/2021 | | | Was | W | Candelario | 10 | 5 | | 71 | 70 | .504 | 6-4 | W3 | 141 |
| 9/8/2021 | | @ | Mtl | L | | 5 | 9 | | 71 | 71 | .500 | 6-4 | L1 | 142 |
| 9/9/2021 | | | Was | W | Smith,Do | 5 | 4 | | 72 | 71 | .503 | 6-4 | W1 | 143 |
| 9/9/2021 | | @ | Mtl | L | | 5 | 6 | | 72 | 72 | .500 | 6-4 | L1 | 144 |
| 9/10/2021 | | | Cle | W | Sanchez,G | 2 | 1 | | 73 | 72 | .503 | 6-4 | W1 | 145 |
| 9/10/2021 | | @ | Tex | W | Candelario | 7 | 1 | | 74 | 72 | .507 | 7-3 | W2 | 146 |
| 9/11/2021 | | | Cle | L | | 4 | 9 | | 74 | 73 | .503 | 6-4 | L1 | 147 |
| 9/11/2021 | | @ | Tex | W | Marte,K | 8 | 4 | | 75 | 73 | .507 | 7-3 | W1 | 148 |
| 9/12/2021 | | | Cle | W | Candelario | 8 | 3 | | 76 | 73 | .510 | 7-3 | W2 | 149 |
| 9/12/2021 | | @ | Tex | W | Ford | 14 | 1 | | 77 | 73 | .513 | 7-3 | W3 | 150 |
| 9/13/2021 | | | Cle | L | | 4 | 5 | | 77 | 74 | .510 | 6-4 | L1 | 151 |
| 9/13/2021 | | @ | Tex | W | Seager,K | 8 | 6 | | 78 | 74 | .513 | 7-3 | W1 | 152 |
| 9/24/2021 | | @ | Bos | L | | 3 | 5 | | 78 | 75 | .510 | 6-4 | L1 | 153 |
| 9/24/2021 | | | Bal | W | Garcia,Av | 3 | 2 | | 79 | 75 | .513 | 7-3 | W1 | 154 |
| 9/25/2021 | | @ | Bos | L | | 3 | 5 | | 79 | 76 | .510 | 6-4 | L1 | 155 |
| 9/25/2021 | | | Bal | W | | 7 | 4 | | 80 | 76 | .513 | 6-4 | W1 | 156 |
| 9/26/2021 | | @ | Bos | W | Ford | 6 | 4 | | 81 | 76 | .516 | 7-3 | W2 | 157 |
| 9/26/2021 | | | Bal | L | | 2 | 6 | | 81 | 77 | .513 | 6-4 | L1 | 158 |
| 9/27/2021 | | | Mtl | W | Quinn,R | 4 | 2 | | 82 | 77 | .516 | 6-4 | W1 | 159 |
| 9/27/2021 | | @ | Mtl | L | | 3 | 6 | | 82 | 78 | .512 | 5-5 | L1 | 160 |
| 9/28/2021 | | | Mtl | W | Santana,Da | 7 | 2 | | 83 | 78 | .516 | 6-4 | W1 | 161 |
| 9/28/2021 | | @ | Mtl | L | | 4 | 7 | | 83 | 79 | .512 | 5-5 | L1 | 162 |