League pitching register -- 2009 American League
Regular season -- as of 10/24/2009
| Primary |
| Name | Team | P | Age | ERA | W | L | S | G | GS | CG | SHO | INN | H | R | ER | BB | K | HR | GDP |
| Alfredo Aceves | Was | sp | 26 | 5.87 | 0 | 1 | 0 | 3 | 3 | 0 | 0 | 15.1 | 21 | 12 | 10 | 11 | 9 | 2 | 1 |
| Nick Adenhart | Bal | sp | 22 | 6.28 | 1 | 1 | 0 | 3 | 3 | 0 | 0 | 14.1 | 20 | 11 | 10 | 6 | 4 | 0 | 2 |
| Jeremy Affeldt* | Bos | mr | 30 | 2.86 | 1 | 0 | 2 | 24 | 0 | 0 | 0 | 28.1 | 24 | 9 | 9 | 13 | 38 | 1 | 2 |
| Jonathan Albaladejo | Min | mr | 26 | 99.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.0 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| Matt Albers | Tex | mr | 26 | 2.62 | 4 | 3 | 0 | 33 | 7 | 0 | 0 | 103.0 | 77 | 31 | 30 | 48 | 56 | 7 | 13 |
| Jose Arredondo | Cle | mr | 25 | 1.14 | 3 | 2 | 4 | 50 | 0 | 0 | 0 | 63.0 | 40 | 11 | 8 | 19 | 57 | 1 | 3 |
| Luis Ayala | Bal | mr | 31 | 4.76 | 7 | 10 | 1 | 60 | 0 | 0 | 0 | 73.2 | 88 | 44 | 39 | 27 | 50 | 8 | 8 |
| Brandon Backe | Bal | sp | 31 | 7.10 | 5 | 15 | 0 | 30 | 30 | 1 | 0 | 161.0 | 217 | 131 | 127 | 89 | 123 | 22 | 21 |
| Burke Badenhop | KCR | sp | 26 | 5.13 | 4 | 2 | 0 | 11 | 10 | 0 | 0 | 59.2 | 60 | 35 | 34 | 27 | 46 | 13 | 7 |
| Cha Seung Baek | NYY | sp | 29 | 7.72 | 5 | 16 | 0 | 26 | 25 | 0 | 0 | 131.2 | 172 | 122 | 113 | 75 | 77 | 21 | 6 |
| Homer Bailey | Tor | sp | 23 | 6.53 | 2 | 1 | 0 | 5 | 5 | 0 | 0 | 20.2 | 33 | 16 | 15 | 10 | 8 | 4 | 2 |
| Josh Banks | Mtl | sp | 26 | 4.54 | 3 | 10 | 1 | 29 | 14 | 0 | 0 | 123.0 | 153 | 67 | 62 | 48 | 61 | 18 | 13 |
| Brian Bass | Bal | mr | 27 | 3.66 | 2 | 0 | 1 | 21 | 2 | 0 | 0 | 66.1 | 70 | 29 | 27 | 12 | 25 | 9 | 9 |
| Miguel Batista | Bal | mr | 38 | 6.30 | 3 | 9 | 0 | 36 | 14 | 1 | 0 | 104.1 | 128 | 77 | 73 | 70 | 64 | 20 | 12 |
| Denny Bautista | Sea | mr | 28 | 12.10 | 0 | 1 | 2 | 10 | 0 | 0 | 0 | 9.2 | 15 | 13 | 13 | 13 | 7 | 2 | 0 |
| T.J. Beam | LAA | mr | 28 | 1.65 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 16.1 | 16 | 4 | 3 | 3 | 14 | 0 | 0 |
| Josh Beckett | KCR | sp | 29 | 3.78 | 12 | 9 | 0 | 30 | 30 | 5 | 1 | 212.0 | 208 | 95 | 89 | 57 | 202 | 18 | 22 |
| Joe Beimel* | Min | mr | 32 | 4.21 | 1 | 1 | 1 | 50 | 0 | 0 | 0 | 68.1 | 69 | 32 | 32 | 32 | 49 | 4 | 6 |
| Matt Belisle | Tex | sp | 29 | 7.24 | 0 | 2 | 0 | 3 | 3 | 0 | 0 | 13.2 | 17 | 12 | 11 | 5 | 5 | 2 | 2 |
| Joaquin Benoit | Oak | mr | 31 | 4.76 | 0 | 2 | 0 | 12 | 0 | 0 | 0 | 5.2 | 4 | 3 | 3 | 7 | 4 | 0 | 0 |
| Jason Bergmann | KCR | sp | 27 | 6.15 | 7 | 11 | 0 | 25 | 25 | 0 | 0 | 139.0 | 171 | 98 | 95 | 39 | 97 | 33 | 9 |
| Randor Bierd | Mtl | mr | 25 | 8.16 | 1 | 1 | 0 | 20 | 0 | 0 | 0 | 32.0 | 49 | 32 | 29 | 11 | 22 | 4 | 0 |
| Jerry Blevins* | Mtl | mr | 25 | 3.12 | 5 | 2 | 7 | 39 | 0 | 0 | 0 | 49.0 | 38 | 17 | 17 | 21 | 41 | 3 | 6 |
| Mitchell Boggs | Det | sp | 25 | 9.18 | 0 | 1 | 0 | 4 | 4 | 0 | 0 | 16.2 | 26 | 23 | 17 | 13 | 15 | 6 | 2 |
| Jeremy Bonderman | Was | sp | 26 | 3.24 | 5 | 2 | 0 | 9 | 9 | 1 | 0 | 58.1 | 60 | 27 | 21 | 22 | 45 | 4 | 7 |
| Eddie Bonine | Tex | sp | 28 | 1.59 | 1 | 0 | 0 | 4 | 4 | 0 | 0 | 28.1 | 27 | 5 | 5 | 5 | 10 | 0 | 4 |
| Michael Bowden | NYY | sp | 22 | 8.22 | 0 | 4 | 0 | 5 | 5 | 0 | 0 | 23.0 | 34 | 25 | 21 | 11 | 15 | 4 | 1 |
| Dallas Braden* | Mtl | sp | 25 | 3.18 | 6 | 2 | 0 | 25 | 13 | 1 | 0 | 121.2 | 120 | 45 | 43 | 31 | 74 | 10 | 14 |
| Chad Bradford | Det | mr | 34 | 3.35 | 7 | 10 | 2 | 60 | 0 | 0 | 0 | 99.1 | 103 | 41 | 37 | 16 | 32 | 6 | 15 |
| Craig Breslow* | NYY | mr | 28 | 2.74 | 3 | 4 | 3 | 48 | 0 | 0 | 0 | 65.2 | 47 | 23 | 20 | 37 | 56 | 0 | 5 |
| Doug Brocail | Tor | mr | 42 | 3.73 | 7 | 4 | 3 | 68 | 0 | 0 | 0 | 113.1 | 97 | 53 | 47 | 43 | 115 | 7 | 11 |
| Andrew Brown | Mtl | mr | 28 | 2.55 | 7 | 4 | 3 | 38 | 0 | 0 | 0 | 60.0 | 37 | 17 | 17 | 20 | 56 | 6 | 3 |
| Brian Bruney |   | mr | 27 | 1.70 | 7 | 2 | 3 | 31 | 5 | 0 | 0 | 74.1 | 36 | 14 | 14 | 30 | 83 | 7 | 1 |
| Clay Buchholz | Cle | sp | 24 | 5.49 | 6 | 4 | 0 | 20 | 20 | 0 | 0 | 98.1 | 117 | 69 | 60 | 52 | 91 | 8 | 5 |
| Taylor Buchholz | ChW | mr | 27 | 3.97 | 1 | 1 | 1 | 7 | 0 | 0 | 0 | 11.1 | 10 | 5 | 5 | 3 | 14 | 0 | 2 |
| Bryan Bullington | Bos | sp | 28 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2.1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
| Brian Burres* | Tex | sp | 28 | 6.68 | 3 | 20 | 0 | 31 | 30 | 0 | 0 | 159.0 | 231 | 136 | 118 | 59 | 80 | 17 | 16 |
| Paul Byrd | Tor | sp | 38 | 4.24 | 11 | 14 | 0 | 30 | 30 | 4 | 0 | 197.1 | 222 | 110 | 93 | 44 | 80 | 33 | 29 |
| Daniel Cabrera | Bal | sp | 28 | 4.87 | 7 | 11 | 0 | 30 | 30 | 0 | 0 | 188.2 | 197 | 116 | 102 | 107 | 92 | 23 | 25 |
| Matt Cain | NYY | sp | 24 | 5.40 | 10 | 15 | 0 | 34 | 34 | 1 | 0 | 198.1 | 219 | 125 | 119 | 92 | 172 | 20 | 18 |
| Shawn Camp | Oak | mr | 33 | 2.70 | 1 | 2 | 1 | 40 | 0 | 0 | 0 | 50.0 | 56 | 18 | 15 | 18 | 39 | 1 | 5 |
| Jorge Campillo | Bos | sp | 30 | 4.96 | 11 | 6 | 0 | 33 | 30 | 0 | 0 | 161.1 | 186 | 94 | 89 | 62 | 135 | 21 | 17 |
| Matt Capps | Sea | cl | 25 | 3.63 | 1 | 9 | 15 | 53 | 0 | 0 | 0 | 74.1 | 70 | 31 | 30 | 11 | 42 | 8 | 4 |
| Vinnie Chulk | Was | mr | 30 | 6.00 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 12.0 | 15 | 9 | 8 | 5 | 8 | 1 | 0 |
| Tyler Clippard | Sea | sp | 24 | 12.27 | 0 | 2 | 0 | 2 | 2 | 0 | 0 | 7.1 | 13 | 10 | 10 | 7 | 4 | 1 | 2 |
| Todd Coffey | Cle | mr | 28 | 1.84 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | 14.2 | 8 | 3 | 3 | 7 | 5 | 1 | 2 |
| Phil Coke* | Bal | mr | 26 | 1.72 | 1 | 2 | 2 | 11 | 0 | 0 | 0 | 15.2 | 9 | 4 | 3 | 2 | 11 | 1 | 0 |
| Bartolo Colon | Sea | sp | 36 | 3.75 | 3 | 4 | 0 | 11 | 11 | 3 | 1 | 72.0 | 78 | 35 | 30 | 16 | 55 | 8 | 6 |
| Francisco Cordero | Tex | cl | 34 | 2.61 | 5 | 3 | 25 | 52 | 0 | 0 | 0 | 62.0 | 53 | 23 | 18 | 32 | 75 | 5 | 6 |
| Lance Cormier | Oak | mr | 28 | 4.10 | 4 | 0 | 2 | 38 | 5 | 1 | 0 | 96.2 | 99 | 49 | 44 | 40 | 60 | 9 | 13 |
| Manuel Corpas | NYY | mr | 26 | 4.97 | 4 | 2 | 2 | 59 | 0 | 0 | 0 | 79.2 | 104 | 47 | 44 | 28 | 52 | 12 | 14 |
| Kevin Correia | Sea | sp | 28 | 6.33 | 5 | 10 | 1 | 23 | 19 | 1 | 1 | 108.0 | 143 | 83 | 76 | 41 | 49 | 11 | 13 |
| Juan Cruz | Cle | mr | 30 | 4.90 | 2 | 1 | 0 | 52 | 0 | 0 | 0 | 64.1 | 50 | 35 | 35 | 54 | 81 | 6 | 4 |
| Johnny Cueto | Sea | sp | 23 | 4.26 | 9 | 15 | 0 | 32 | 32 | 0 | 0 | 186.0 | 196 | 106 | 88 | 87 | 170 | 23 | 16 |
| Eulogio De La Cruz | ChW | mr | 25 | 9.26 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 11.2 | 13 | 12 | 12 | 14 | 4 | 3 | 3 |
| Jorge De La Rosa* | Was | sp | 28 | 4.33 | 12 | 10 | 2 | 31 | 26 | 0 | 0 | 166.1 | 156 | 84 | 80 | 85 | 175 | 14 | 19 |
| Manny Delcarmen | Cle | mr | 27 | 2.02 | 7 | 1 | 37 | 59 | 0 | 0 | 0 | 58.0 | 38 | 13 | 13 | 13 | 51 | 3 | 4 |
| Ryan Dempster | LAA | sp | 32 | 3.40 | 16 | 8 | 0 | 33 | 33 | 2 | 1 | 217.0 | 187 | 90 | 82 | 82 | 178 | 13 | 24 |
| Joey Devine | Bos | mr | 25 | 1.13 | 9 | 0 | 9 | 46 | 0 | 0 | 0 | 103.1 | 54 | 15 | 13 | 26 | 106 | 1 | 7 |
| R.A. Dickey | Min | mr | 34 | 3.72 | 7 | 1 | 0 | 18 | 18 | 0 | 0 | 101.2 | 97 | 43 | 42 | 42 | 67 | 8 | 3 |
| Mark DiFelice | Bos | mr | 32 | 10.59 | 0 | 1 | 0 | 20 | 0 | 0 | 0 | 17.0 | 24 | 23 | 20 | 9 | 23 | 6 | 0 |
| Tim Dillard | Min | mr | 25 | 27.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 2 | 3 | 3 | 2 | 1 | 1 | 0 |
| Octavio Dotel | Mtl | mr | 35 | 4.74 | 5 | 7 | 32 | 60 | 0 | 0 | 0 | 74.0 | 63 | 40 | 39 | 23 | 94 | 18 | 5 |
| Scott Downs* | LAA | mr | 33 | 2.89 | 3 | 9 | 16 | 65 | 0 | 0 | 0 | 96.2 | 74 | 33 | 31 | 26 | 77 | 6 | 10 |
| Justin Duchscherer | Cle | sp | 31 | 2.55 | 17 | 5 | 1 | 26 | 25 | 5 | 4 | 187.1 | 136 | 56 | 53 | 27 | 122 | 10 | 15 |
| Zach Duke* | Tor | sp | 26 | 5.36 | 3 | 8 | 0 | 16 | 15 | 1 | 0 | 82.1 | 115 | 54 | 49 | 28 | 44 | 5 | 8 |
| Chad Durbin | KCR | mr | 31 | 2.53 | 7 | 3 | 3 | 67 | 0 | 0 | 0 | 99.2 | 89 | 29 | 28 | 43 | 58 | 6 | 19 |
| Adam Eaton | Bal | sp | 31 | 6.34 | 4 | 11 | 0 | 22 | 22 | 1 | 0 | 132.0 | 176 | 99 | 93 | 43 | 62 | 23 | 24 |
| Scott Elarton | LAA | mr | 33 | 0.00 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 2.0 | 2 | 2 | 0 | 0 | 2 | 1 | 0 |
| Alan Embree* | Sea | mr | 39 | 4.47 | 6 | 5 | 0 | 70 | 0 | 0 | 0 | 110.2 | 99 | 62 | 55 | 53 | 113 | 15 | 17 |
| Shawn Estes* | Sea | sp | 36 | 5.91 | 4 | 5 | 0 | 12 | 12 | 0 | 0 | 64.0 | 77 | 50 | 42 | 32 | 16 | 9 | 8 |
| Dana Eveland* | LAA | sp | 25 | 3.18 | 15 | 6 | 0 | 30 | 30 | 0 | 0 | 181.1 | 162 | 68 | 64 | 86 | 133 | 10 | 31 |
| Scott Eyre* | LAA | mr | 37 | 2.76 | 1 | 2 | 1 | 32 | 0 | 0 | 0 | 42.1 | 28 | 14 | 13 | 8 | 45 | 6 | 7 |
| Kyle Farnsworth | Mtl | mr | 33 | 6.94 | 1 | 0 | 1 | 17 | 0 | 0 | 0 | 23.1 | 33 | 19 | 18 | 9 | 26 | 7 | 2 |
| Ryan Feierabend* | ChW | sp | 23 | 8.44 | 2 | 11 | 0 | 20 | 20 | 0 | 0 | 90.2 | 140 | 95 | 85 | 48 | 51 | 17 | 12 |
| Pedro Feliciano* | NYY | mr | 32 | 4.41 | 1 | 4 | 2 | 52 | 0 | 0 | 0 | 69.1 | 76 | 35 | 34 | 21 | 63 | 5 | 6 |
| Nelson Figueroa | KCR | mr | 35 | 8.10 | 1 | 0 | 0 | 12 | 3 | 0 | 0 | 23.1 | 42 | 21 | 21 | 22 | 15 | 1 | 4 |
| Keith Foulke | Was | mr | 36 | 14.54 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 4.1 | 5 | 7 | 7 | 4 | 3 | 0 | 0 |
| Jeff Francis* | ChW | sp | 28 | 5.28 | 6 | 10 | 0 | 28 | 28 | 1 | 0 | 172.0 | 214 | 109 | 101 | 53 | 119 | 20 | 12 |
| Ryan Franklin | Det | mr | 36 | 6.63 | 2 | 3 | 2 | 43 | 0 | 0 | 0 | 55.2 | 78 | 41 | 41 | 27 | 31 | 8 | 5 |
| Eric Gagne | Tor | mr | 33 | 3.77 | 1 | 1 | 2 | 29 | 0 | 0 | 0 | 45.1 | 37 | 19 | 19 | 20 | 29 | 6 | 6 |
| Freddy Garcia | Min | sp | 33 | 4.46 | 3 | 2 | 0 | 6 | 6 | 1 | 0 | 38.1 | 31 | 19 | 19 | 11 | 29 | 8 | 2 |
| Jaime Garcia* | Sea | mr | 22 | 5.51 | 1 | 1 | 0 | 16 | 1 | 0 | 0 | 32.2 | 37 | 20 | 20 | 21 | 25 | 7 | 4 |
| Jon Garland | Mtl | sp | 29 | 5.84 | 12 | 14 | 0 | 32 | 32 | 0 | 0 | 183.1 | 228 | 126 | 119 | 61 | 81 | 26 | 33 |
| Matt Garza | Bal | sp | 25 | 4.30 | 9 | 14 | 0 | 30 | 30 | 2 | 0 | 198.2 | 197 | 101 | 95 | 55 | 155 | 32 | 24 |
| Geoff Geary | LAA | mr | 32 | 2.55 | 6 | 2 | 2 | 49 | 0 | 0 | 0 | 77.2 | 58 | 23 | 22 | 25 | 48 | 4 | 8 |
| Josh Geer | ChW | sp | 26 | 3.86 | 3 | 4 | 0 | 9 | 9 | 0 | 0 | 53.2 | 62 | 33 | 23 | 16 | 32 | 6 | 4 |
| Franklyn German | Min | mr | 29 | 2.45 | 1 | 0 | 0 | 13 | 0 | 0 | 0 | 18.1 | 21 | 7 | 5 | 14 | 14 | 0 | 4 |
| Justin Germano | Tex | sp | 26 | 7.02 | 1 | 1 | 1 | 10 | 2 | 0 | 0 | 33.1 | 47 | 27 | 26 | 8 | 15 | 5 | 7 |
| Matt Ginter | Min | sp | 31 | 1.72 | 2 | 0 | 0 | 2 | 2 | 0 | 0 | 15.2 | 15 | 3 | 3 | 2 | 9 | 0 | 2 |
| Gary Glover | Tor | mr | 32 | 3.78 | 4 | 2 | 2 | 42 | 0 | 0 | 0 | 88.0 | 101 | 39 | 37 | 29 | 61 | 8 | 7 |
| Jimmy Gobble* | Tor | mr | 27 | 8.31 | 1 | 2 | 0 | 10 | 1 | 0 | 0 | 8.2 | 12 | 9 | 8 | 8 | 6 | 1 | 0 |
| Edgar Gonzalez | LAA | mr | 26 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2.0 | 1 | 0 | 0 | 0 | 2 | 0 | 0 |
| Gio Gonzalez* | Sea | sp | 23 | 5.72 | 3 | 5 | 0 | 12 | 11 | 0 | 0 | 56.2 | 53 | 39 | 36 | 50 | 56 | 14 | 6 |
| Mike Gonzalez* | Cle | cl | 31 | 3.67 | 2 | 3 | 0 | 28 | 0 | 0 | 0 | 27.0 | 26 | 11 | 11 | 6 | 44 | 3 | 0 |
| Tom Gorzelanny* | Sea | sp | 26 | 5.78 | 4 | 12 | 0 | 25 | 25 | 0 | 0 | 129.1 | 141 | 84 | 83 | 93 | 73 | 18 | 23 |
| Sean Green | ChW | mr | 30 | 3.38 | 8 | 8 | 6 | 59 | 0 | 0 | 0 | 88.0 | 84 | 45 | 33 | 35 | 67 | 4 | 11 |
| Zack Greinke | Bos | sp | 25 | 3.47 | 19 | 10 | 0 | 32 | 32 | 2 | 1 | 218.0 | 215 | 89 | 84 | 47 | 198 | 17 | 17 |
| Matt Guerrier | Cle | mr | 30 | 5.70 | 2 | 3 | 1 | 56 | 0 | 0 | 0 | 60.0 | 77 | 40 | 38 | 29 | 54 | 5 | 3 |
| Charlie Haeger | Cle | mr | 25 | 6.23 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 4.1 | 6 | 3 | 3 | 3 | 9 | 2 | 0 |
| Jason Hammel | ChW | mr | 26 | 4.43 | 6 | 3 | 1 | 47 | 0 | 0 | 0 | 91.1 | 85 | 52 | 45 | 33 | 47 | 15 | 9 |
| Mike Hampton* | Cle | sp | 36 | 5.79 | 6 | 8 | 0 | 15 | 15 | 0 | 0 | 84.0 | 98 | 61 | 54 | 23 | 39 | 16 | 8 |
| Joel Hanrahan | Tex | mr | 27 | 3.29 | 3 | 5 | 4 | 67 | 0 | 0 | 0 | 125.2 | 100 | 51 | 46 | 52 | 143 | 7 | 11 |
| J.A. Happ* | LAA | sp | 26 | 5.70 | 4 | 1 | 0 | 5 | 5 | 0 | 0 | 23.2 | 23 | 15 | 15 | 18 | 21 | 0 | 3 |
| Aaron Harang | Tor | sp | 31 | 4.54 | 12 | 12 | 0 | 30 | 30 | 3 | 2 | 188.1 | 208 | 100 | 95 | 48 | 146 | 31 | 9 |
| Aaron Heilman | Tor | mr | 30 | 4.25 | 3 | 2 | 1 | 29 | 0 | 0 | 0 | 36.0 | 34 | 22 | 17 | 29 | 46 | 1 | 3 |
| Mark Hendrickson* | Was | sp | 35 | 3.80 | 8 | 6 | 0 | 26 | 22 | 1 | 0 | 139.2 | 150 | 67 | 59 | 38 | 89 | 15 | 9 |
| Clay Hensley | Was | mr | 29 | 3.68 | 2 | 2 | 0 | 16 | 4 | 0 | 0 | 36.2 | 29 | 20 | 15 | 20 | 23 | 2 | 6 |
| Felix Hernandez | Min | sp | 23 | 4.18 | 11 | 14 | 0 | 32 | 32 | 3 | 2 | 213.1 | 222 | 108 | 99 | 100 | 181 | 16 | 22 |
| Alex Hinshaw* | NYY | mr | 26 | 8.15 | 1 | 1 | 0 | 16 | 0 | 0 | 0 | 17.2 | 25 | 17 | 16 | 14 | 23 | 4 | 2 |
| Luke Hochevar | NYY | sp | 25 | 4.51 | 7 | 12 | 0 | 26 | 26 | 1 | 0 | 163.2 | 163 | 88 | 82 | 55 | 90 | 25 | 22 |
| J.P. Howell* | Bos | mr | 26 | 3.54 | 5 | 7 | 17 | 56 | 0 | 0 | 0 | 68.2 | 60 | 29 | 27 | 32 | 73 | 6 | 3 |
| Tim Hudson | Det | sp | 33 | 3.19 | 7 | 5 | 0 | 14 | 14 | 1 | 1 | 96.0 | 88 | 34 | 34 | 37 | 55 | 8 | 13 |
| Jason Isringhausen | Oak | cl | 36 | 0.00 | 1 | 0 | 0 | 4 | 0 | 0 | 0 | 2.0 | 4 | 0 | 0 | 2 | 1 | 0 | 0 |
| Edwin Jackson | Min | sp | 25 | 5.29 | 7 | 15 | 0 | 31 | 31 | 1 | 0 | 170.0 | 191 | 112 | 100 | 67 | 114 | 20 | 15 |
| Zach Jackson* | ChW | sp | 26 | 5.70 | 0 | 0 | 2 | 25 | 0 | 0 | 0 | 60.0 | 69 | 39 | 38 | 15 | 42 | 4 | 7 |
| Chuck James* | Sea | sp | 27 | 7.23 | 0 | 2 | 0 | 5 | 5 | 0 | 0 | 23.2 | 31 | 19 | 19 | 12 | 23 | 3 | 1 |
| Bobby Jenks | KCR | cl | 28 | 1.97 | 8 | 2 | 35 | 61 | 0 | 0 | 0 | 68.2 | 53 | 15 | 15 | 12 | 42 | 2 | 8 |
| Jason Johnson | Was | mr | 35 | 3.96 | 2 | 1 | 0 | 4 | 4 | 0 | 0 | 25.0 | 29 | 12 | 11 | 5 | 12 | 3 | 5 |
| Josh Johnson | Min | sp | 25 | 4.47 | 6 | 10 | 0 | 19 | 19 | 2 | 0 | 116.2 | 131 | 60 | 58 | 42 | 102 | 10 | 21 |
| Todd Jones | Mtl | cl | 41 | 3.75 | 0 | 0 | 1 | 16 | 0 | 0 | 0 | 24.0 | 23 | 11 | 10 | 8 | 12 | 2 | 3 |
| Jorge Julio | Oak | mr | 30 | 4.91 | 3 | 1 | 0 | 25 | 0 | 0 | 0 | 36.2 | 32 | 21 | 20 | 22 | 53 | 4 | 5 |
| Jair Jurrjens | Mtl | sp | 23 | 4.13 | 12 | 12 | 0 | 31 | 31 | 2 | 1 | 194.0 | 225 | 96 | 89 | 66 | 139 | 10 | 31 |
| Scott Kazmir* | Bos | sp | 25 | 3.75 | 16 | 9 | 0 | 30 | 30 | 1 | 1 | 177.2 | 139 | 82 | 74 | 86 | 200 | 22 | 13 |
| Kyle Kendrick | Det | sp | 24 | 4.68 | 7 | 8 | 0 | 23 | 23 | 1 | 0 | 134.2 | 156 | 75 | 70 | 53 | 66 | 7 | 11 |
| Logan Kensing | Was | mr | 26 | 5.12 | 0 | 0 | 0 | 38 | 0 | 0 | 0 | 58.0 | 50 | 33 | 33 | 38 | 47 | 5 | 7 |
| Masa Kobayashi | Bal | mr | 35 | 3.91 | 2 | 3 | 0 | 47 | 0 | 0 | 0 | 66.2 | 66 | 30 | 29 | 9 | 42 | 7 | 4 |
| Eddie Kunz | ChW | mr | 23 | 3.24 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 8.1 | 5 | 3 | 3 | 4 | 5 | 0 | 4 |
| Hong-Chih Kuo* | Bos | mr | 27 | 2.93 | 4 | 5 | 6 | 46 | 3 | 0 | 0 | 116.2 | 99 | 38 | 38 | 24 | 148 | 8 | 5 |
| John Lackey | Cle | sp | 30 | 4.70 | 8 | 11 | 0 | 28 | 28 | 3 | 2 | 185.2 | 200 | 105 | 97 | 42 | 134 | 29 | 26 |
| John Lannan* | Was | sp | 24 | 5.27 | 7 | 15 | 0 | 32 | 31 | 0 | 0 | 179.1 | 184 | 119 | 105 | 101 | 111 | 21 | 21 |
| Brandon League | Min | mr | 26 | 4.47 | 2 | 3 | 0 | 29 | 0 | 0 | 0 | 46.1 | 47 | 26 | 23 | 15 | 35 | 2 | 6 |
| Wil Ledezma* | Was | mr | 28 | 7.88 | 2 | 4 | 1 | 16 | 8 | 0 | 0 | 48.0 | 43 | 43 | 42 | 48 | 46 | 7 | 2 |
| Jensen Lewis | Cle | cl | 25 | 4.04 | 3 | 5 | 1 | 49 | 0 | 0 | 0 | 78.0 | 79 | 38 | 35 | 39 | 62 | 7 | 8 |
| Brad Lidge | ChW | cl | 32 | 9.39 | 0 | 1 | 0 | 5 | 0 | 0 | 0 | 7.2 | 8 | 8 | 8 | 5 | 11 | 1 | 1 |
| Mike Lincoln | Sea | mr | 34 | 4.17 | 6 | 4 | 3 | 65 | 0 | 0 | 0 | 114.1 | 113 | 59 | 53 | 36 | 105 | 17 | 7 |
| Scott Linebrink | LAA | mr | 32 | 2.24 | 6 | 7 | 14 | 48 | 0 | 0 | 0 | 64.1 | 46 | 22 | 16 | 14 | 63 | 4 | 3 |
| Francisco Liriano* | Min | sp | 25 | 3.64 | 7 | 6 | 0 | 18 | 18 | 0 | 0 | 108.2 | 92 | 45 | 44 | 53 | 93 | 12 | 9 |
| Wes Littleton | Cle | mr | 26 | 0.57 | 1 | 0 | 0 | 13 | 0 | 0 | 0 | 15.2 | 14 | 2 | 1 | 5 | 8 | 0 | 5 |
| Esteban Loaiza | Oak | mr | 37 | 1.13 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 8.0 | 2 | 1 | 1 | 1 | 3 | 0 | 0 |
| Boone Logan* | ChW | mr | 24 | 8.35 | 1 | 3 | 6 | 40 | 0 | 0 | 0 | 46.1 | 84 | 46 | 43 | 18 | 45 | 9 | 2 |
| Kyle Lohse | Bos | sp | 30 | 5.38 | 11 | 14 | 0 | 33 | 33 | 0 | 0 | 182.1 | 227 | 117 | 109 | 47 | 124 | 21 | 16 |
| Braden Looper | Tex | sp | 34 | 4.80 | 7 | 17 | 0 | 34 | 33 | 3 | 1 | 202.2 | 235 | 120 | 108 | 53 | 100 | 28 | 32 |
| Aquilino Lopez | Was | mr | 34 | 4.50 | 1 | 4 | 1 | 34 | 0 | 0 | 0 | 62.0 | 70 | 32 | 31 | 8 | 47 | 7 | 5 |
| Javier Lopez* | Tex | mr | 31 | 3.05 | 6 | 4 | 4 | 51 | 0 | 0 | 0 | 73.2 | 64 | 26 | 25 | 28 | 52 | 4 | 8 |
| Mark Lowe | Bos | mr | 26 | 6.62 | 0 | 0 | 0 | 16 | 0 | 0 | 0 | 17.2 | 25 | 15 | 13 | 17 | 8 | 1 | 2 |
| Ryan Madson | NYY | mr | 28 | 5.03 | 1 | 7 | 2 | 59 | 0 | 0 | 0 | 82.1 | 100 | 51 | 46 | 26 | 72 | 11 | 7 |
| Charlie Manning* | LAA | mr | 30 | 5.40 | 1 | 1 | 0 | 34 | 0 | 0 | 0 | 41.2 | 38 | 26 | 25 | 37 | 39 | 10 | 7 |
| Carlos Marmol | Bal | mr | 26 | 1.22 | 4 | 4 | 28 | 50 | 0 | 0 | 0 | 59.0 | 33 | 9 | 8 | 34 | 83 | 4 | 0 |
| Damaso Marte* | Cle | mr | 34 | 3.13 | 3 | 0 | 1 | 60 | 0 | 0 | 0 | 54.2 | 56 | 20 | 19 | 32 | 68 | 2 | 3 |
| Shairon Martis | KCR | sp | 22 | 4.62 | 3 | 2 | 0 | 9 | 7 | 0 | 0 | 39.0 | 32 | 22 | 20 | 23 | 50 | 9 | 2 |
| Tom Mastny | Tex | mr | 28 | 7.84 | 2 | 2 | 0 | 4 | 4 | 0 | 0 | 20.2 | 26 | 18 | 18 | 10 | 14 | 7 | 3 |
| Doug Mathis | Tor | sp | 26 | 9.00 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 6.0 | 10 | 7 | 6 | 2 | 3 | 2 | 0 |
| Daisuke Matsuzaka | NYY | sp | 28 | 3.67 | 10 | 12 | 0 | 30 | 30 | 4 | 2 | 201.1 | 143 | 85 | 82 | 119 | 186 | 8 | 14 |
| Kyle McClellan | Bal | mr | 25 | 4.48 | 4 | 1 | 2 | 50 | 0 | 0 | 0 | 72.1 | 72 | 39 | 36 | 32 | 58 | 8 | 4 |
| Dustin McGowan | Cle | sp | 27 | 5.00 | 7 | 8 | 0 | 21 | 21 | 0 | 0 | 122.1 | 149 | 72 | 68 | 40 | 114 | 11 | 6 |
| Gil Meche | KCR | sp | 30 | 3.27 | 15 | 12 | 0 | 34 | 34 | 4 | 2 | 223.0 | 199 | 87 | 81 | 90 | 223 | 20 | 18 |
| Andrew Miller* | LAA | sp | 24 | 5.29 | 7 | 7 | 0 | 25 | 19 | 0 | 0 | 110.2 | 132 | 67 | 65 | 48 | 96 | 3 | 8 |
| Jim Miller | Bos | mr | 27 | 0.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.1 | 1 | 0 | 0 | 0 | 3 | 0 | 0 |
| Trever Miller* | Tor | mr | 36 | 4.91 | 2 | 3 | 0 | 27 | 0 | 0 | 0 | 33.0 | 36 | 18 | 18 | 20 | 29 | 2 | 10 |
| Kevin Millwood | Mtl | sp | 34 | 4.28 | 10 | 6 | 0 | 30 | 30 | 1 | 0 | 193.2 | 234 | 99 | 92 | 55 | 125 | 21 | 15 |
| Zach Miner | Det | mr | 27 | 3.41 | 6 | 2 | 1 | 35 | 5 | 0 | 0 | 89.2 | 75 | 38 | 34 | 23 | 50 | 5 | 7 |
| Brian Moehler | Tex | sp | 37 | 5.15 | 6 | 18 | 0 | 30 | 30 | 1 | 0 | 187.0 | 224 | 121 | 107 | 45 | 93 | 28 | 16 |
| Brandon Morrow | Was | mr | 24 | 2.30 | 9 | 2 | 4 | 40 | 3 | 0 | 0 | 86.0 | 48 | 22 | 22 | 34 | 94 | 10 | 4 |
| Charlie Morton | Det | sp | 25 | 7.38 | 2 | 9 | 0 | 14 | 14 | 0 | 0 | 61.0 | 84 | 51 | 50 | 41 | 28 | 9 | 6 |
| Guillermo Mota |   | mr | 35 | 4.05 | 2 | 2 | 2 | 53 | 0 | 0 | 0 | 80.0 | 74 | 37 | 36 | 42 | 66 | 8 | 11 |
| Jason Motte | Was | mr | 27 | 3.55 | 2 | 2 | 1 | 8 | 0 | 0 | 0 | 12.2 | 12 | 5 | 5 | 6 | 9 | 0 | 3 |
| Edward Mujica | Min | mr | 25 | 5.40 | 2 | 1 | 1 | 14 | 0 | 0 | 0 | 25.0 | 33 | 17 | 15 | 6 | 16 | 2 | 5 |
| Mike Mussina | Bos | sp | 40 | 3.94 | 14 | 9 | 0 | 34 | 34 | 2 | 0 | 219.1 | 243 | 100 | 96 | 33 | 161 | 7 | 20 |
| Brett Myers | Oak | sp | 28 | 3.98 | 16 | 7 | 0 | 30 | 30 | 2 | 1 | 203.2 | 186 | 95 | 90 | 69 | 168 | 23 | 19 |
| Joe Nelson | Bos | mr | 34 | 3.18 | 5 | 3 | 15 | 54 | 0 | 0 | 0 | 82.0 | 60 | 29 | 29 | 30 | 101 | 4 | 4 |
| Jonathon Niese* | ChW | sp | 22 | 10.69 | 0 | 5 | 0 | 7 | 7 | 0 | 0 | 33.2 | 62 | 43 | 40 | 17 | 24 | 7 | 6 |
| Fernando Nieve | Bos | mr | 26 | 23.14 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.1 | 5 | 6 | 6 | 4 | 0 | 1 | 0 |
| Dustin Nippert | ChW | mr | 28 | 5.42 | 5 | 5 | 0 | 17 | 17 | 0 | 0 | 98.0 | 118 | 61 | 59 | 37 | 83 | 15 | 6 |
| Hideki Okajima* | Was | mr | 33 | 3.12 | 3 | 3 | 5 | 31 | 0 | 0 | 0 | 40.1 | 33 | 17 | 14 | 23 | 34 | 4 | 3 |
| Darren Oliver* | Oak | mr | 38 | 2.97 | 9 | 2 | 12 | 57 | 0 | 0 | 0 | 66.2 | 62 | 23 | 22 | 8 | 50 | 3 | 9 |
| Garrett Olson* | LAA | sp | 25 | 5.34 | 6 | 8 | 0 | 27 | 27 | 0 | 0 | 146.2 | 169 | 92 | 87 | 62 | 121 | 14 | 13 |
| Vicente Padilla | KCR | sp | 31 | 4.62 | 12 | 12 | 0 | 31 | 31 | 1 | 1 | 191.0 | 194 | 107 | 98 | 72 | 161 | 23 | 22 |
| Matt Palmer | Tor | sp | 30 | 14.54 | 0 | 2 | 0 | 2 | 2 | 0 | 0 | 4.1 | 9 | 9 | 7 | 5 | 0 | 0 | 2 |
| Jonathan Papelbon | Min | cl | 28 | 1.92 | 3 | 5 | 35 | 65 | 0 | 0 | 0 | 89.0 | 71 | 19 | 19 | 14 | 94 | 6 | 5 |
| Manny Parra* | NYY | sp | 26 | 5.74 | 4 | 10 | 0 | 31 | 30 | 1 | 0 | 152.0 | 193 | 103 | 97 | 82 | 133 | 27 | 13 |
| John Parrish* | Mtl | mr | 31 | 4.94 | 1 | 1 | 0 | 16 | 2 | 0 | 0 | 27.1 | 28 | 15 | 15 | 20 | 14 | 1 | 2 |
| Scott Patterson | Cle | mr | 30 | 27.00 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 1.2 | 7 | 8 | 5 | 3 | 1 | 0 | 0 |
| Carl Pavano | Cle | sp | 33 | 6.40 | 3 | 3 | 0 | 10 | 10 | 0 | 0 | 45.0 | 60 | 34 | 32 | 20 | 32 | 5 | 2 |
| Jake Peavy | Oak | sp | 28 | 3.36 | 12 | 10 | 0 | 30 | 30 | 2 | 1 | 198.1 | 198 | 81 | 74 | 63 | 197 | 22 | 10 |
| Tony Pena | Oak | mr | 27 | 3.39 | 10 | 5 | 3 | 61 | 0 | 0 | 0 | 82.1 | 86 | 38 | 31 | 22 | 65 | 3 | 9 |
| Joel Peralta | Tex | mr | 33 | 5.64 | 1 | 2 | 0 | 40 | 0 | 0 | 0 | 83.0 | 83 | 56 | 52 | 26 | 64 | 24 | 6 |
| Troy Percival | LAA | cl | 39 | 4.66 | 4 | 6 | 10 | 46 | 0 | 0 | 0 | 58.0 | 40 | 30 | 30 | 27 | 50 | 19 | 1 |
| Chris Perez | Mtl | mr | 23 | 4.67 | 0 | 2 | 1 | 31 | 0 | 0 | 0 | 34.2 | 32 | 19 | 18 | 26 | 33 | 1 | 7 |
| Odalis Perez* | Tor | sp | 32 | 5.69 | 8 | 10 | 0 | 31 | 31 | 0 | 0 | 153.1 | 204 | 106 | 97 | 59 | 104 | 19 | 19 |
| Oliver Perez* | LAA | sp | 27 | 6.52 | 6 | 7 | 0 | 17 | 17 | 0 | 0 | 89.2 | 111 | 71 | 65 | 50 | 76 | 6 | 4 |
| Glen Perkins* | Oak | sp | 26 | 4.35 | 11 | 6 | 0 | 30 | 30 | 2 | 0 | 190.1 | 220 | 103 | 92 | 50 | 111 | 25 | 22 |
| Scott Proctor | Mtl | mr | 32 | 5.50 | 2 | 1 | 0 | 25 | 0 | 0 | 0 | 36.0 | 32 | 22 | 22 | 19 | 39 | 6 | 1 |
| David Purcey* | ChW | sp | 27 | 5.40 | 5 | 5 | 0 | 16 | 16 | 0 | 0 | 93.1 | 107 | 59 | 56 | 35 | 91 | 16 | 6 |
| Horacio Ramirez* |   | mr | 29 | 5.51 | 0 | 3 | 1 | 34 | 0 | 0 | 0 | 49.0 | 55 | 31 | 30 | 13 | 22 | 1 | 2 |
| Ramon Ramirez | Oak | mr | 27 | 1.43 | 5 | 5 | 19 | 66 | 0 | 0 | 0 | 88.0 | 57 | 15 | 14 | 31 | 85 | 1 | 9 |
| Ramon Ramirez | Det | sp | 26 | 1.80 | 2 | 0 | 0 | 2 | 2 | 0 | 0 | 15.0 | 7 | 3 | 3 | 7 | 15 | 2 | 1 |
| Tim Redding | Was | sp | 31 | 4.73 | 15 | 12 | 0 | 33 | 33 | 3 | 0 | 218.2 | 235 | 121 | 115 | 97 | 151 | 30 | 17 |
| Mark Redman* | Sea | sp | 35 | 7.77 | 3 | 6 | 0 | 12 | 12 | 0 | 0 | 63.2 | 89 | 59 | 55 | 26 | 27 | 14 | 10 |
| Chris Resop | Cle | mr | 26 | 10.93 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 14.0 | 18 | 17 | 17 | 6 | 12 | 3 | 0 |
| Anthony Reyes | Cle | sp | 27 | 5.34 | 6 | 3 | 0 | 18 | 8 | 1 | 1 | 62.1 | 76 | 39 | 37 | 22 | 38 | 6 | 8 |
| Clayton Richard* | Tex | sp | 25 | 5.20 | 5 | 5 | 0 | 25 | 13 | 0 | 0 | 97.0 | 112 | 60 | 56 | 27 | 66 | 10 | 7 |
| Scott Richmond | Min | sp | 29 | 4.54 | 3 | 0 | 0 | 5 | 5 | 1 | 0 | 37.2 | 44 | 19 | 19 | 6 | 25 | 3 | 4 |
| Juan Rincon | Sea | mr | 30 | 5.56 | 1 | 3 | 0 | 53 | 0 | 0 | 0 | 89.0 | 119 | 58 | 55 | 42 | 75 | 16 | 8 |
| Francisco Rodriguez | Tor | cl | 27 | 3.31 | 4 | 3 | 24 | 71 | 0 | 0 | 0 | 87.0 | 69 | 38 | 32 | 45 | 84 | 5 | 10 |
| Kenny Rogers* | Tex | sp | 44 | 4.73 | 10 | 10 | 0 | 30 | 30 | 1 | 0 | 171.1 | 207 | 101 | 90 | 68 | 89 | 22 | 27 |
| J.C. Romero* | Det | mr | 33 | 3.64 | 2 | 5 | 4 | 59 | 0 | 0 | 0 | 81.2 | 52 | 37 | 33 | 61 | 78 | 7 | 8 |
| Sergio Romo | Min | mr | 26 | 2.61 | 2 | 0 | 2 | 25 | 0 | 0 | 0 | 41.1 | 24 | 12 | 12 | 14 | 36 | 5 | 0 |
| Carlos Rosa | KCR | mr | 24 | 5.87 | 0 | 2 | 0 | 5 | 0 | 0 | 0 | 7.2 | 10 | 7 | 5 | 5 | 5 | 1 | 1 |
| Leo Rosales | Tor | mr | 28 | 81.00 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 0.1 | 4 | 4 | 3 | 2 | 0 | 0 | 0 |
| Josh Rupe | ChW | mr | 26 | 4.60 | 2 | 3 | 0 | 37 | 0 | 0 | 0 | 94.0 | 90 | 50 | 48 | 53 | 51 | 11 | 17 |
| B.J. Ryan* |   | cl | 33 | 2.59 | 2 | 6 | 39 | 62 | 0 | 0 | 0 | 80.0 | 58 | 24 | 23 | 37 | 75 | 4 | 10 |
| C.C. Sabathia* | Oak | sp | 28 | 4.18 | 16 | 10 | 0 | 35 | 35 | 6 | 1 | 241.0 | 251 | 123 | 112 | 53 | 249 | 29 | 14 |
| Jeff Samardzija | ChW | mr | 24 | 5.50 | 0 | 5 | 14 | 28 | 0 | 0 | 0 | 36.0 | 39 | 23 | 22 | 24 | 26 | 3 | 5 |
| Chris Sampson | NYY | mr | 31 | 3.68 | 9 | 3 | 0 | 31 | 12 | 0 | 0 | 129.2 | 133 | 58 | 53 | 25 | 54 | 9 | 17 |
| Duaner Sanchez | Bos | mr | 29 | 3.81 | 3 | 0 | 1 | 39 | 0 | 0 | 0 | 52.0 | 52 | 28 | 22 | 24 | 33 | 5 | 1 |
| Johan Santana* | Sea | sp | 30 | 3.83 | 12 | 12 | 0 | 32 | 32 | 5 | 2 | 216.1 | 196 | 101 | 92 | 75 | 185 | 23 | 19 |
| Joe Saunders* | LAA | sp | 28 | 3.26 | 12 | 6 | 0 | 31 | 31 | 4 | 2 | 215.1 | 200 | 86 | 78 | 47 | 120 | 18 | 29 |
| Max Scherzer | Tor | mr | 24 | 3.31 | 7 | 2 | 0 | 11 | 11 | 1 | 0 | 73.1 | 63 | 30 | 27 | 43 | 74 | 4 | 15 |
| Scott Schoeneweis* | Det | mr | 35 | 5.74 | 3 | 3 | 1 | 47 | 0 | 0 | 0 | 69.0 | 84 | 47 | 44 | 35 | 45 | 9 | 13 |
| Bobby Seay* | Bal | mr | 31 | 3.90 | 6 | 2 | 0 | 51 | 0 | 0 | 0 | 64.2 | 76 | 29 | 28 | 22 | 75 | 5 | 6 |
| Ben Sheets | Oak | sp | 30 | 4.61 | 9 | 12 | 0 | 31 | 31 | 2 | 1 | 205.0 | 214 | 120 | 105 | 66 | 177 | 17 | 14 |
| George Sherrill* | KCR | cl | 32 | 3.75 | 6 | 9 | 5 | 56 | 0 | 0 | 0 | 72.0 | 62 | 36 | 30 | 37 | 85 | 9 | 3 |
| Scot Shields | Min | mr | 33 | 2.75 | 5 | 4 | 1 | 58 | 0 | 0 | 0 | 95.0 | 78 | 31 | 29 | 32 | 89 | 8 | 17 |
| Kevin Slowey | Tor | sp | 25 | 3.78 | 13 | 9 | 0 | 30 | 30 | 5 | 0 | 207.0 | 209 | 94 | 87 | 45 | 146 | 20 | 11 |
| Greg Smith* | Det | sp | 25 | 4.29 | 9 | 8 | 0 | 32 | 32 | 2 | 1 | 184.2 | 155 | 95 | 88 | 79 | 100 | 28 | 16 |
| Joe Smith | Tor | mr | 25 | 4.85 | 3 | 4 | 5 | 56 | 0 | 0 | 0 | 85.1 | 74 | 48 | 46 | 55 | 62 | 4 | 12 |
| John Smoltz | Mtl | sp | 42 | 4.89 | 4 | 4 | 0 | 9 | 9 | 0 | 0 | 57.0 | 60 | 32 | 31 | 16 | 67 | 6 | 1 |
| Ian Snell | Tex | sp | 27 | 10.13 | 2 | 4 | 0 | 6 | 6 | 0 | 0 | 24.0 | 39 | 28 | 27 | 11 | 15 | 3 | 2 |
| Rafael Soriano | Min | mr | 29 | 7.84 | 4 | 1 | 0 | 11 | 0 | 0 | 0 | 10.1 | 10 | 10 | 9 | 18 | 17 | 1 | 1 |
| Jeremy Sowers* | Det | sp | 26 | 2.92 | 7 | 6 | 0 | 18 | 18 | 3 | 1 | 120.1 | 111 | 42 | 39 | 41 | 64 | 8 | 16 |
| Justin Speier | NYY | mr | 35 | 3.60 | 4 | 3 | 1 | 47 | 0 | 0 | 0 | 70.0 | 56 | 32 | 28 | 22 | 56 | 12 | 1 |
| Russ Springer | Min | mr | 40 | 4.63 | 4 | 3 | 0 | 53 | 0 | 0 | 0 | 72.0 | 73 | 37 | 37 | 33 | 74 | 12 | 2 |
| Mitch Stetter* | Was | mr | 28 | 5.40 | 1 | 4 | 1 | 33 | 0 | 0 | 0 | 26.2 | 25 | 16 | 16 | 23 | 37 | 1 | 0 |
| Brian Stokes | Was | mr | 29 | 3.82 | 2 | 1 | 0 | 9 | 4 | 0 | 0 | 33.0 | 44 | 14 | 14 | 5 | 28 | 0 | 7 |
| Huston Street | NYY | cl | 25 | 2.81 | 5 | 5 | 25 | 55 | 0 | 0 | 0 | 77.0 | 64 | 26 | 24 | 37 | 76 | 6 | 6 |
| Jeff Suppan | Bal | sp | 34 | 5.71 | 6 | 15 | 0 | 31 | 31 | 1 | 0 | 186.0 | 249 | 136 | 118 | 68 | 96 | 26 | 33 |
| Jack Taschner* | NYY | mr | 31 | 6.00 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 6.0 | 8 | 4 | 4 | 3 | 5 | 1 | 0 |
| Brad Thompson | KCR | mr | 27 | 5.95 | 1 | 2 | 0 | 30 | 4 | 0 | 0 | 75.2 | 105 | 54 | 50 | 29 | 35 | 12 | 11 |
| Rich Thompson | Mtl | mr | 24 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 3.2 | 4 | 0 | 0 | 1 | 2 | 0 | 1 |
| Ramon Troncoso | Tex | mr | 26 | 2.70 | 1 | 1 | 0 | 5 | 0 | 0 | 0 | 10.0 | 11 | 3 | 3 | 2 | 12 | 1 | 1 |
| Justin Verlander | Cle | sp | 26 | 4.25 | 15 | 11 | 0 | 33 | 33 | 1 | 1 | 207.2 | 201 | 110 | 98 | 76 | 183 | 19 | 15 |
| Edinson Volquez | Mtl | sp | 25 | 4.54 | 12 | 8 | 0 | 31 | 31 | 0 | 0 | 178.1 | 171 | 101 | 90 | 95 | 188 | 17 | 12 |
| Chris Volstad | KCR | sp | 22 | 2.94 | 8 | 4 | 0 | 18 | 18 | 3 | 1 | 119.1 | 116 | 43 | 39 | 48 | 58 | 5 | 21 |
| Doug Waechter | ChW | mr | 28 | 5.72 | 6 | 2 | 3 | 37 | 0 | 0 | 0 | 50.1 | 64 | 33 | 32 | 13 | 41 | 7 | 4 |
| Tim Wakefield | Min | sp | 42 | 3.32 | 16 | 10 | 0 | 31 | 31 | 7 | 1 | 214.1 | 173 | 83 | 79 | 69 | 132 | 22 | 18 |
| Jamie Walker* | Bal | mr | 37 | 5.96 | 1 | 2 | 0 | 37 | 0 | 0 | 0 | 48.1 | 59 | 34 | 32 | 12 | 34 | 16 | 4 |
| Tyler Walker | Sea | mr | 33 | 3.78 | 4 | 4 | 1 | 69 | 0 | 0 | 0 | 102.1 | 90 | 47 | 43 | 42 | 103 | 18 | 4 |
| Jarrod Washburn* | Det | sp | 34 | 5.95 | 6 | 12 | 0 | 26 | 26 | 0 | 0 | 130.0 | 162 | 96 | 86 | 55 | 64 | 21 | 18 |
| Chris Waters* | Tor | sp | 28 | 3.00 | 0 | 1 | 0 | 5 | 5 | 0 | 0 | 30.0 | 27 | 15 | 10 | 12 | 21 | 0 | 1 |
| David Weathers | Det | mr | 39 | 2.51 | 3 | 0 | 1 | 37 | 0 | 0 | 0 | 68.0 | 62 | 20 | 19 | 20 | 46 | 3 | 7 |
| Brandon Webb | Det | sp | 30 | 3.72 | 13 | 7 | 0 | 24 | 24 | 3 | 1 | 171.2 | 176 | 76 | 71 | 52 | 141 | 14 | 17 |
| Kip Wells | Tex | mr | 32 | 6.75 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 4.0 | 4 | 3 | 3 | 3 | 2 | 1 | 0 |
| Dontrelle Willis* | Was | sp | 27 | 6.35 | 3 | 2 | 0 | 10 | 10 | 0 | 0 | 51.0 | 32 | 36 | 36 | 48 | 36 | 6 | 3 |
| C.J. Wilson* | KCR | cl | 28 | 4.00 | 6 | 0 | 1 | 52 | 0 | 0 | 0 | 74.1 | 68 | 33 | 33 | 40 | 61 | 8 | 10 |
| Randy Wolf* | ChW | sp | 32 | 5.29 | 8 | 15 | 0 | 33 | 33 | 3 | 0 | 207.2 | 228 | 133 | 122 | 81 | 150 | 24 | 34 |
| Brian Wolfe | Mtl | mr | 28 | 7.22 | 2 | 5 | 1 | 25 | 0 | 0 | 0 | 28.2 | 36 | 23 | 23 | 15 | 25 | 6 | 3 |
| Kerry Wood | Det | cl | 32 | 3.00 | 2 | 5 | 26 | 58 | 0 | 0 | 0 | 72.0 | 80 | 27 | 24 | 35 | 86 | 1 | 6 |
| Michael Wuertz | Tex | mr | 30 | 4.98 | 5 | 3 | 3 | 40 | 0 | 0 | 0 | 47.0 | 62 | 26 | 26 | 20 | 40 | 8 | 2 |
| Yasuhiko Yabuta | Cle | mr | 36 | 0.00 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 4.2 | 4 | 0 | 0 | 0 | 0 | 0 | 3 |
| Charlie Zink | Cle | sp | 29 | 5.91 | 1 | 1 | 0 | 2 | 2 | 0 | 0 | 10.2 | 12 | 8 | 7 | 4 | 7 | 0 | 1 |
| Barry Zito* | ChW | sp | 31 | 6.61 | 9 | 19 | 0 | 32 | 32 | 0 | 0 | 178.1 | 191 | 139 | 131 | 138 | 122 | 23 | 16 |
| Joel Zumaya | KCR | mr | 24 | 3.47 | 0 | 2 | 0 | 27 | 0 | 0 | 0 | 49.1 | 31 | 20 | 19 | 36 | 40 | 2 | 4 |
| Secondary |
| Name | Team | P | Age | SB | CS | IW | HBP | WP | BK | SH | SF | H/9 | BB/9 | R/9 | K/9 | HR/9 | K/BB | WHIP |
| Alfredo Aceves | Was | sp | 26 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 12.3 | 6.5 | 18.8 | 5.3 | 1.2 | 0.8 | 2.09 |
| Nick Adenhart | Bal | sp | 22 | 1 | 0 | 0 | 1 | 2 | 0 | 0 | 1 | 12.6 | 3.8 | 17.0 | 2.5 | 0.0 | 0.7 | 1.81 |
| Jeremy Affeldt* | Bos | mr | 30 | 1 | 1 | 0 | 3 | 1 | 0 | 0 | 0 | 7.6 | 4.1 | 12.7 | 12.1 | 0.3 | 2.9 | 1.31 |
| Jonathan Albaladejo | Min | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 99.0 | 0.0 | 99.0 | 0.0 | 0.0 | 0.0 | 0.00 |
| Matt Albers | Tex | mr | 26 | 3 | 4 | 1 | 8 | 1 | 0 | 2 | 3 | 6.7 | 4.2 | 11.6 | 4.9 | 0.6 | 1.2 | 1.21 |
| Jose Arredondo | Cle | mr | 25 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 2 | 5.7 | 2.7 | 8.4 | 8.1 | 0.1 | 3.0 | 0.94 |
| Luis Ayala | Bal | mr | 31 | 3 | 4 | 6 | 5 | 0 | 0 | 3 | 2 | 10.8 | 3.3 | 14.7 | 6.1 | 1.0 | 1.9 | 1.56 |
| Brandon Backe | Bal | sp | 31 | 6 | 2 | 2 | 7 | 2 | 0 | 7 | 10 | 12.1 | 5.0 | 17.5 | 6.9 | 1.2 | 1.4 | 1.90 |
| Burke Badenhop | KCR | sp | 26 | 1 | 0 | 1 | 4 | 2 | 0 | 0 | 0 | 9.1 | 4.1 | 13.7 | 6.9 | 2.0 | 1.7 | 1.46 |
| Cha Seung Baek | NYY | sp | 29 | 10 | 4 | 3 | 4 | 5 | 0 | 4 | 6 | 11.8 | 5.1 | 17.2 | 5.3 | 1.4 | 1.0 | 1.88 |
| Homer Bailey | Tor | sp | 23 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 14.4 | 4.4 | 18.7 | 3.5 | 1.7 | 0.8 | 2.08 |
| Josh Banks | Mtl | sp | 26 | 17 | 3 | 4 | 4 | 0 | 0 | 3 | 2 | 11.2 | 3.5 | 15.0 | 4.5 | 1.3 | 1.3 | 1.63 |
| Brian Bass | Bal | mr | 27 | 1 | 0 | 1 | 3 | 2 | 0 | 1 | 2 | 9.5 | 1.6 | 11.5 | 3.4 | 1.2 | 2.1 | 1.24 |
| Miguel Batista | Bal | mr | 38 | 8 | 3 | 2 | 8 | 2 | 0 | 4 | 7 | 11.0 | 6.0 | 17.8 | 5.5 | 1.7 | 0.9 | 1.90 |
| Denny Bautista | Sea | mr | 28 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 14.0 | 12.1 | 26.1 | 6.5 | 1.9 | 0.5 | 2.90 |
| T.J. Beam | LAA | mr | 28 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 8.8 | 1.7 | 10.5 | 7.7 | 0.0 | 4.7 | 1.16 |
| Josh Beckett | KCR | sp | 29 | 7 | 10 | 1 | 14 | 5 | 0 | 1 | 3 | 8.8 | 2.4 | 11.8 | 8.6 | 0.8 | 3.5 | 1.25 |
| Joe Beimel* | Min | mr | 32 | 2 | 1 | 3 | 4 | 1 | 2 | 2 | 2 | 9.1 | 4.2 | 13.8 | 6.5 | 0.5 | 1.5 | 1.48 |
| Matt Belisle | Tex | sp | 29 | 3 | 0 | 0 | 0 | 3 | 0 | 1 | 0 | 11.2 | 3.3 | 14.5 | 3.3 | 1.3 | 1.0 | 1.61 |
| Joaquin Benoit | Oak | mr | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.4 | 11.1 | 17.5 | 6.4 | 0.0 | 0.6 | 1.94 |
| Jason Bergmann | KCR | sp | 27 | 14 | 4 | 0 | 1 | 4 | 0 | 1 | 4 | 11.1 | 2.5 | 13.7 | 6.3 | 2.1 | 2.5 | 1.51 |
| Randor Bierd | Mtl | mr | 25 | 0 | 0 | 2 | 2 | 1 | 0 | 0 | 5 | 13.8 | 3.1 | 17.4 | 6.2 | 1.1 | 2.0 | 1.88 |
| Jerry Blevins* | Mtl | mr | 25 | 4 | 0 | 3 | 1 | 1 | 0 | 0 | 1 | 7.0 | 3.9 | 11.0 | 7.5 | 0.6 | 2.0 | 1.20 |
| Mitchell Boggs | Det | sp | 25 | 0 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 14.0 | 7.0 | 21.6 | 8.1 | 3.2 | 1.2 | 2.34 |
| Jeremy Bonderman | Was | sp | 26 | 3 | 3 | 2 | 4 | 2 | 0 | 1 | 2 | 9.3 | 3.4 | 13.3 | 6.9 | 0.6 | 2.0 | 1.41 |
| Eddie Bonine | Tex | sp | 28 | 1 | 1 | 2 | 3 | 2 | 0 | 3 | 0 | 8.6 | 1.6 | 11.1 | 3.2 | 0.0 | 2.0 | 1.13 |
| Michael Bowden | NYY | sp | 22 | 3 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 13.3 | 4.3 | 17.6 | 5.9 | 1.6 | 1.4 | 1.96 |
| Dallas Braden* | Mtl | sp | 25 | 1 | 1 | 0 | 4 | 0 | 4 | 2 | 5 | 8.9 | 2.3 | 11.5 | 5.5 | 0.7 | 2.4 | 1.24 |
| Chad Bradford | Det | mr | 34 | 7 | 4 | 6 | 8 | 0 | 1 | 2 | 0 | 9.3 | 1.4 | 11.5 | 2.9 | 0.5 | 2.0 | 1.20 |
| Craig Breslow* | NYY | mr | 28 | 1 | 1 | 3 | 0 | 8 | 3 | 0 | 2 | 6.4 | 5.1 | 11.5 | 7.7 | 0.0 | 1.5 | 1.28 |
| Doug Brocail | Tor | mr | 42 | 16 | 1 | 16 | 8 | 2 | 1 | 2 | 6 | 7.7 | 3.4 | 11.8 | 9.1 | 0.6 | 2.7 | 1.24 |
| Andrew Brown | Mtl | mr | 28 | 5 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 5.5 | 3.0 | 8.7 | 8.4 | 0.9 | 2.8 | 0.95 |
| Brian Bruney |   | mr | 27 | 2 | 1 | 1 | 2 | 1 | 0 | 5 | 0 | 4.4 | 3.6 | 8.2 | 10.0 | 0.8 | 2.8 | 0.89 |
| Clay Buchholz | Cle | sp | 24 | 4 | 1 | 0 | 3 | 6 | 1 | 4 | 4 | 10.7 | 4.8 | 15.7 | 8.3 | 0.7 | 1.8 | 1.72 |
| Taylor Buchholz | ChW | mr | 27 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 7.9 | 2.4 | 11.1 | 11.1 | 0.0 | 4.7 | 1.15 |
| Bryan Bullington | Bos | sp | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.9 | 0.0 | 3.9 | 3.9 | 0.0 | 99.0 | 0.43 |
| Brian Burres* | Tex | sp | 28 | 15 | 4 | 1 | 5 | 2 | 2 | 3 | 12 | 13.1 | 3.3 | 16.7 | 4.5 | 1.0 | 1.4 | 1.82 |
| Paul Byrd | Tor | sp | 38 | 8 | 2 | 5 | 5 | 0 | 0 | 4 | 12 | 10.1 | 2.0 | 12.4 | 3.6 | 1.5 | 1.8 | 1.35 |
| Daniel Cabrera | Bal | sp | 28 | 17 | 8 | 8 | 14 | 13 | 1 | 4 | 7 | 9.4 | 5.1 | 15.2 | 4.4 | 1.1 | 0.9 | 1.61 |
| Matt Cain | NYY | sp | 24 | 9 | 5 | 3 | 8 | 4 | 3 | 8 | 6 | 9.9 | 4.2 | 14.5 | 7.8 | 0.9 | 1.9 | 1.57 |
| Shawn Camp | Oak | mr | 33 | 2 | 1 | 9 | 3 | 0 | 0 | 2 | 2 | 10.1 | 3.2 | 13.9 | 7.0 | 0.2 | 2.2 | 1.48 |
| Jorge Campillo | Bos | sp | 30 | 11 | 2 | 0 | 5 | 0 | 0 | 4 | 11 | 10.4 | 3.5 | 14.1 | 7.5 | 1.2 | 2.2 | 1.54 |
| Matt Capps | Sea | cl | 25 | 2 | 2 | 1 | 2 | 1 | 0 | 1 | 7 | 8.5 | 1.3 | 10.0 | 5.1 | 1.0 | 3.8 | 1.09 |
| Vinnie Chulk | Was | mr | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11.3 | 3.8 | 15.0 | 6.0 | 0.8 | 1.6 | 1.67 |
| Tyler Clippard | Sea | sp | 24 | 2 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 16.0 | 8.6 | 24.5 | 4.9 | 1.2 | 0.6 | 2.73 |
| Todd Coffey | Cle | mr | 28 | 0 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 4.9 | 4.3 | 10.4 | 3.1 | 0.6 | 0.7 | 1.02 |
| Phil Coke* | Bal | mr | 26 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.2 | 1.1 | 6.3 | 6.3 | 0.6 | 5.5 | 0.70 |
| Bartolo Colon | Sea | sp | 36 | 5 | 1 | 4 | 2 | 0 | 0 | 0 | 3 | 9.8 | 2.0 | 12.0 | 6.9 | 1.0 | 3.4 | 1.31 |
| Francisco Cordero | Tex | cl | 34 | 3 | 0 | 2 | 2 | 3 | 0 | 3 | 0 | 7.7 | 4.6 | 12.6 | 10.9 | 0.7 | 2.3 | 1.37 |
| Lance Cormier | Oak | mr | 28 | 6 | 1 | 0 | 2 | 3 | 1 | 2 | 0 | 9.2 | 3.7 | 13.1 | 5.6 | 0.8 | 1.5 | 1.44 |
| Manuel Corpas | NYY | mr | 26 | 4 | 2 | 1 | 3 | 2 | 0 | 2 | 4 | 11.7 | 3.2 | 15.3 | 5.9 | 1.4 | 1.9 | 1.66 |
| Kevin Correia | Sea | sp | 28 | 1 | 2 | 0 | 7 | 5 | 0 | 2 | 3 | 11.9 | 3.4 | 15.9 | 4.1 | 0.9 | 1.2 | 1.70 |
| Juan Cruz | Cle | mr | 30 | 2 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 7.0 | 7.6 | 14.5 | 11.3 | 0.8 | 1.5 | 1.62 |
| Johnny Cueto | Sea | sp | 23 | 4 | 4 | 3 | 7 | 4 | 1 | 0 | 9 | 9.5 | 4.2 | 14.0 | 8.2 | 1.1 | 2.0 | 1.52 |
| Eulogio De La Cruz | ChW | mr | 25 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 10.0 | 10.8 | 20.8 | 3.1 | 2.3 | 0.3 | 2.31 |
| Jorge De La Rosa* | Was | sp | 28 | 13 | 6 | 2 | 5 | 14 | 2 | 6 | 6 | 8.4 | 4.6 | 13.3 | 9.5 | 0.8 | 2.1 | 1.45 |
| Manny Delcarmen | Cle | mr | 27 | 2 | 0 | 1 | 2 | 0 | 0 | 0 | 5 | 5.9 | 2.0 | 8.2 | 7.9 | 0.5 | 3.9 | 0.88 |
| Ryan Dempster | LAA | sp | 32 | 10 | 3 | 1 | 9 | 1 | 0 | 2 | 6 | 7.8 | 3.4 | 11.5 | 7.4 | 0.5 | 2.2 | 1.24 |
| Joey Devine | Bos | mr | 25 | 5 | 2 | 0 | 1 | 6 | 0 | 1 | 5 | 4.7 | 2.3 | 7.1 | 9.2 | 0.1 | 4.1 | 0.77 |
| R.A. Dickey | Min | mr | 34 | 5 | 3 | 1 | 1 | 8 | 1 | 1 | 3 | 8.6 | 3.7 | 12.4 | 5.9 | 0.7 | 1.6 | 1.37 |
| Mark DiFelice | Bos | mr | 32 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 12.7 | 4.8 | 17.5 | 12.2 | 3.2 | 2.6 | 1.94 |
| Tim Dillard | Min | mr | 25 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 18.0 | 18.0 | 36.0 | 9.0 | 9.0 | 0.5 | 4.00 |
| Octavio Dotel | Mtl | mr | 35 | 2 | 3 | 3 | 3 | 4 | 0 | 3 | 4 | 7.7 | 2.8 | 10.8 | 11.4 | 2.2 | 4.1 | 1.16 |
| Scott Downs* | LAA | mr | 33 | 5 | 1 | 2 | 3 | 2 | 0 | 2 | 1 | 6.9 | 2.4 | 9.6 | 7.2 | 0.6 | 3.0 | 1.03 |
| Justin Duchscherer | Cle | sp | 31 | 12 | 5 | 1 | 9 | 0 | 0 | 4 | 2 | 6.5 | 1.3 | 8.3 | 5.9 | 0.5 | 4.5 | 0.87 |
| Zach Duke* | Tor | sp | 26 | 7 | 1 | 5 | 6 | 0 | 1 | 1 | 5 | 12.6 | 3.1 | 16.3 | 4.8 | 0.5 | 1.6 | 1.74 |
| Chad Durbin | KCR | mr | 31 | 4 | 1 | 3 | 3 | 5 | 0 | 5 | 4 | 8.0 | 3.9 | 12.2 | 5.2 | 0.5 | 1.3 | 1.32 |
| Adam Eaton | Bal | sp | 31 | 2 | 3 | 0 | 7 | 1 | 0 | 4 | 4 | 12.0 | 2.9 | 15.4 | 4.2 | 1.6 | 1.4 | 1.66 |
| Scott Elarton | LAA | mr | 33 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 0.0 | 9.0 | 9.0 | 4.5 | 99.0 | 1.00 |
| Alan Embree* | Sea | mr | 39 | 2 | 1 | 3 | 3 | 4 | 0 | 1 | 9 | 8.1 | 4.3 | 12.6 | 9.2 | 1.2 | 2.1 | 1.37 |
| Shawn Estes* | Sea | sp | 36 | 2 | 1 | 1 | 2 | 2 | 0 | 1 | 1 | 10.8 | 4.5 | 15.6 | 2.3 | 1.3 | 0.5 | 1.70 |
| Dana Eveland* | LAA | sp | 25 | 13 | 2 | 3 | 13 | 2 | 1 | 3 | 8 | 8.0 | 4.3 | 13.0 | 6.6 | 0.5 | 1.5 | 1.37 |
| Scott Eyre* | LAA | mr | 37 | 3 | 0 | 0 | 3 | 0 | 0 | 0 | 1 | 6.0 | 1.7 | 8.3 | 9.6 | 1.3 | 5.6 | 0.85 |
| Kyle Farnsworth | Mtl | mr | 33 | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 12.7 | 3.5 | 16.2 | 10.0 | 2.7 | 2.9 | 1.80 |
| Ryan Feierabend* | ChW | sp | 23 | 0 | 1 | 2 | 0 | 0 | 1 | 3 | 7 | 13.9 | 4.8 | 18.7 | 5.1 | 1.7 | 1.1 | 2.07 |
| Pedro Feliciano* | NYY | mr | 32 | 4 | 2 | 2 | 2 | 4 | 0 | 0 | 0 | 9.9 | 2.7 | 12.9 | 8.2 | 0.6 | 3.0 | 1.40 |
| Nelson Figueroa | KCR | mr | 35 | 0 | 2 | 0 | 0 | 1 | 0 | 0 | 3 | 16.2 | 8.5 | 24.7 | 5.8 | 0.4 | 0.7 | 2.74 |
| Keith Foulke | Was | mr | 36 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 10.4 | 8.3 | 18.7 | 6.2 | 0.0 | 0.8 | 2.08 |
| Jeff Francis* | ChW | sp | 28 | 13 | 2 | 0 | 5 | 0 | 0 | 4 | 9 | 11.2 | 2.8 | 14.2 | 6.2 | 1.0 | 2.2 | 1.55 |
| Ryan Franklin | Det | mr | 36 | 0 | 1 | 3 | 2 | 4 | 0 | 2 | 3 | 12.6 | 4.4 | 17.3 | 5.0 | 1.3 | 1.1 | 1.89 |
| Eric Gagne | Tor | mr | 33 | 0 | 0 | 3 | 3 | 2 | 0 | 0 | 0 | 7.3 | 4.0 | 11.9 | 5.8 | 1.2 | 1.5 | 1.26 |
| Freddy Garcia | Min | sp | 33 | 4 | 1 | 0 | 2 | 1 | 0 | 0 | 0 | 7.3 | 2.6 | 10.3 | 6.8 | 1.9 | 2.6 | 1.10 |
| Jaime Garcia* | Sea | mr | 22 | 1 | 0 | 2 | 2 | 8 | 0 | 0 | 1 | 10.2 | 5.8 | 16.5 | 6.9 | 1.9 | 1.2 | 1.78 |
| Jon Garland | Mtl | sp | 29 | 7 | 2 | 3 | 8 | 0 | 0 | 4 | 7 | 11.2 | 3.0 | 14.6 | 4.0 | 1.3 | 1.3 | 1.58 |
| Matt Garza | Bal | sp | 25 | 12 | 3 | 1 | 5 | 5 | 1 | 5 | 10 | 8.9 | 2.5 | 11.6 | 7.0 | 1.4 | 2.8 | 1.27 |
| Geoff Geary | LAA | mr | 32 | 7 | 1 | 2 | 2 | 1 | 0 | 1 | 1 | 6.7 | 2.9 | 9.8 | 5.6 | 0.5 | 1.9 | 1.07 |
| Josh Geer | ChW | sp | 26 | 3 | 0 | 2 | 1 | 1 | 0 | 0 | 3 | 10.4 | 2.7 | 13.2 | 5.4 | 1.0 | 2.0 | 1.45 |
| Franklyn German | Min | mr | 29 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 10.3 | 6.9 | 17.2 | 6.9 | 0.0 | 1.0 | 1.91 |
| Justin Germano | Tex | sp | 26 | 4 | 0 | 0 | 2 | 4 | 0 | 0 | 1 | 12.7 | 2.2 | 15.4 | 4.0 | 1.3 | 1.9 | 1.65 |
| Matt Ginter | Min | sp | 31 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.6 | 1.1 | 9.8 | 5.2 | 0.0 | 4.5 | 1.09 |
| Gary Glover | Tor | mr | 32 | 1 | 0 | 5 | 2 | 5 | 0 | 1 | 3 | 10.3 | 3.0 | 13.5 | 6.2 | 0.8 | 2.1 | 1.48 |
| Jimmy Gobble* | Tor | mr | 27 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 1 | 12.5 | 8.3 | 20.8 | 6.2 | 1.0 | 0.8 | 2.31 |
| Edgar Gonzalez | LAA | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.5 | 0.0 | 4.5 | 9.0 | 0.0 | 99.0 | 0.50 |
| Gio Gonzalez* | Sea | sp | 23 | 1 | 0 | 2 | 1 | 0 | 0 | 1 | 1 | 8.4 | 7.9 | 16.5 | 8.9 | 2.2 | 1.1 | 1.82 |
| Mike Gonzalez* | Cle | cl | 31 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 8.7 | 2.0 | 11.0 | 14.7 | 1.0 | 7.3 | 1.19 |
| Tom Gorzelanny* | Sea | sp | 26 | 9 | 1 | 6 | 5 | 6 | 0 | 2 | 7 | 9.8 | 6.5 | 16.6 | 5.1 | 1.3 | 0.8 | 1.81 |
| Sean Green | ChW | mr | 30 | 4 | 1 | 1 | 2 | 6 | 0 | 0 | 0 | 8.6 | 3.6 | 12.4 | 6.9 | 0.4 | 1.9 | 1.35 |
| Zack Greinke | Bos | sp | 25 | 8 | 3 | 1 | 4 | 8 | 1 | 4 | 9 | 8.9 | 1.9 | 11.0 | 8.2 | 0.7 | 4.2 | 1.20 |
| Matt Guerrier | Cle | mr | 30 | 5 | 2 | 1 | 1 | 0 | 0 | 1 | 0 | 11.5 | 4.3 | 16.0 | 8.1 | 0.8 | 1.9 | 1.77 |
| Charlie Haeger | Cle | mr | 25 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 12.5 | 6.2 | 22.8 | 18.7 | 4.2 | 3.0 | 2.08 |
| Jason Hammel | ChW | mr | 26 | 9 | 4 | 1 | 1 | 5 | 0 | 4 | 2 | 8.4 | 3.3 | 11.7 | 4.6 | 1.5 | 1.4 | 1.29 |
| Mike Hampton* | Cle | sp | 36 | 0 | 3 | 1 | 0 | 0 | 0 | 2 | 1 | 10.5 | 2.5 | 13.0 | 4.2 | 1.7 | 1.7 | 1.44 |
| Joel Hanrahan | Tex | mr | 27 | 9 | 0 | 3 | 5 | 10 | 0 | 1 | 7 | 7.2 | 3.7 | 11.2 | 10.2 | 0.5 | 2.8 | 1.21 |
| J.A. Happ* | LAA | sp | 26 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 8.7 | 6.8 | 15.6 | 8.0 | 0.0 | 1.2 | 1.73 |
| Aaron Harang | Tor | sp | 31 | 12 | 1 | 2 | 2 | 0 | 0 | 2 | 6 | 9.9 | 2.3 | 12.3 | 7.0 | 1.5 | 3.0 | 1.36 |
| Aaron Heilman | Tor | mr | 30 | 3 | 0 | 4 | 1 | 0 | 0 | 0 | 1 | 8.5 | 7.3 | 16.0 | 11.5 | 0.3 | 1.6 | 1.75 |
| Mark Hendrickson* | Was | sp | 35 | 11 | 6 | 0 | 3 | 2 | 0 | 5 | 6 | 9.7 | 2.4 | 12.3 | 5.7 | 1.0 | 2.3 | 1.35 |
| Clay Hensley | Was | mr | 29 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 7.1 | 4.9 | 12.3 | 5.6 | 0.5 | 1.1 | 1.34 |
| Felix Hernandez | Min | sp | 23 | 17 | 11 | 7 | 11 | 8 | 0 | 3 | 6 | 9.4 | 4.2 | 14.0 | 7.6 | 0.7 | 1.8 | 1.51 |
| Alex Hinshaw* | NYY | mr | 26 | 3 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 12.7 | 7.1 | 20.4 | 11.7 | 2.0 | 1.6 | 2.21 |
| Luke Hochevar | NYY | sp | 25 | 15 | 6 | 1 | 6 | 2 | 0 | 1 | 4 | 9.0 | 3.0 | 12.3 | 4.9 | 1.4 | 1.6 | 1.33 |
| J.P. Howell* | Bos | mr | 26 | 6 | 1 | 2 | 3 | 5 | 0 | 0 | 1 | 7.9 | 4.2 | 12.5 | 9.6 | 0.8 | 2.3 | 1.34 |
| Tim Hudson | Det | sp | 33 | 2 | 2 | 5 | 2 | 0 | 1 | 2 | 1 | 8.3 | 3.5 | 11.9 | 5.2 | 0.8 | 1.5 | 1.30 |
| Jason Isringhausen | Oak | cl | 36 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 18.0 | 9.0 | 27.0 | 4.5 | 0.0 | 0.5 | 3.00 |
| Edwin Jackson | Min | sp | 25 | 6 | 3 | 1 | 3 | 6 | 2 | 4 | 7 | 10.1 | 3.5 | 13.8 | 6.0 | 1.1 | 1.7 | 1.52 |
| Zach Jackson* | ChW | sp | 26 | 1 | 0 | 0 | 4 | 4 | 0 | 0 | 4 | 10.3 | 2.3 | 13.2 | 6.3 | 0.6 | 2.8 | 1.40 |
| Chuck James* | Sea | sp | 27 | 1 | 1 | 1 | 4 | 0 | 2 | 0 | 0 | 11.8 | 4.6 | 17.9 | 8.7 | 1.1 | 1.9 | 1.82 |
| Bobby Jenks | KCR | cl | 28 | 1 | 0 | 1 | 2 | 1 | 0 | 2 | 0 | 6.9 | 1.6 | 8.8 | 5.5 | 0.3 | 3.5 | 0.95 |
| Jason Johnson | Was | mr | 35 | 0 | 0 | 1 | 4 | 1 | 0 | 1 | 1 | 10.4 | 1.8 | 13.7 | 4.3 | 1.1 | 2.4 | 1.36 |
| Josh Johnson | Min | sp | 25 | 8 | 3 | 2 | 2 | 3 | 0 | 1 | 3 | 10.1 | 3.2 | 13.5 | 7.9 | 0.8 | 2.4 | 1.48 |
| Todd Jones | Mtl | cl | 41 | 0 | 0 | 0 | 1 | 4 | 0 | 0 | 2 | 8.6 | 3.0 | 12.0 | 4.5 | 0.8 | 1.5 | 1.29 |
| Jorge Julio | Oak | mr | 30 | 1 | 0 | 1 | 0 | 5 | 0 | 1 | 0 | 7.9 | 5.4 | 13.3 | 13.0 | 1.0 | 2.4 | 1.47 |
| Jair Jurrjens | Mtl | sp | 23 | 13 | 4 | 1 | 6 | 3 | 0 | 4 | 6 | 10.4 | 3.1 | 13.8 | 6.4 | 0.5 | 2.1 | 1.50 |
| Scott Kazmir* | Bos | sp | 25 | 12 | 3 | 1 | 7 | 3 | 0 | 3 | 2 | 7.0 | 4.4 | 11.8 | 10.1 | 1.1 | 2.3 | 1.27 |
| Kyle Kendrick | Det | sp | 24 | 7 | 3 | 4 | 13 | 6 | 0 | 4 | 5 | 10.4 | 3.5 | 14.8 | 4.4 | 0.5 | 1.2 | 1.55 |
| Logan Kensing | Was | mr | 26 | 8 | 2 | 1 | 3 | 6 | 0 | 0 | 5 | 7.8 | 5.9 | 14.1 | 7.3 | 0.8 | 1.2 | 1.52 |
| Masa Kobayashi | Bal | mr | 35 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 8.9 | 1.2 | 10.1 | 5.7 | 0.9 | 4.7 | 1.13 |
| Eddie Kunz | ChW | mr | 23 | 0 | 0 | 0 | 8 | 4 | 0 | 0 | 0 | 5.4 | 4.3 | 18.4 | 5.4 | 0.0 | 1.3 | 1.08 |
| Hong-Chih Kuo* | Bos | mr | 27 | 4 | 3 | 2 | 1 | 2 | 3 | 0 | 3 | 7.6 | 1.9 | 9.6 | 11.4 | 0.6 | 6.2 | 1.05 |
| John Lackey | Cle | sp | 30 | 12 | 5 | 1 | 7 | 5 | 0 | 2 | 4 | 9.7 | 2.0 | 12.1 | 6.5 | 1.4 | 3.2 | 1.30 |
| John Lannan* | Was | sp | 24 | 12 | 8 | 5 | 10 | 5 | 0 | 3 | 6 | 9.2 | 5.1 | 14.8 | 5.6 | 1.1 | 1.1 | 1.59 |
| Brandon League | Min | mr | 26 | 2 | 1 | 1 | 2 | 0 | 0 | 0 | 4 | 9.1 | 2.9 | 12.4 | 6.8 | 0.4 | 2.3 | 1.34 |
| Wil Ledezma* | Was | mr | 28 | 10 | 0 | 0 | 3 | 4 | 0 | 1 | 5 | 8.1 | 9.0 | 17.6 | 8.6 | 1.3 | 1.0 | 1.90 |
| Jensen Lewis | Cle | cl | 25 | 1 | 1 | 0 | 7 | 0 | 0 | 5 | 5 | 9.1 | 4.5 | 14.4 | 7.2 | 0.8 | 1.6 | 1.51 |
| Brad Lidge | ChW | cl | 32 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 9.4 | 5.9 | 15.3 | 12.9 | 1.2 | 2.2 | 1.70 |
| Mike Lincoln | Sea | mr | 34 | 5 | 1 | 3 | 7 | 6 | 0 | 3 | 6 | 8.9 | 2.8 | 12.3 | 8.3 | 1.3 | 2.9 | 1.30 |
| Scott Linebrink | LAA | mr | 32 | 4 | 2 | 0 | 2 | 5 | 0 | 1 | 1 | 6.4 | 2.0 | 8.7 | 8.8 | 0.6 | 4.5 | 0.93 |
| Francisco Liriano* | Min | sp | 25 | 3 | 5 | 2 | 5 | 2 | 0 | 1 | 4 | 7.6 | 4.4 | 12.4 | 7.7 | 1.0 | 1.8 | 1.33 |
| Wes Littleton | Cle | mr | 26 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 8.0 | 2.9 | 12.1 | 4.6 | 0.0 | 1.6 | 1.21 |
| Esteban Loaiza | Oak | mr | 37 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.3 | 1.1 | 4.5 | 3.4 | 0.0 | 3.0 | 0.38 |
| Boone Logan* | ChW | mr | 24 | 0 | 0 | 1 | 0 | 1 | 0 | 3 | 0 | 16.3 | 3.5 | 19.8 | 8.7 | 1.7 | 2.5 | 2.20 |
| Kyle Lohse | Bos | sp | 30 | 19 | 0 | 0 | 5 | 4 | 0 | 1 | 5 | 11.2 | 2.3 | 13.8 | 6.1 | 1.0 | 2.6 | 1.50 |
| Braden Looper | Tex | sp | 34 | 10 | 1 | 2 | 8 | 3 | 2 | 2 | 7 | 10.4 | 2.4 | 13.1 | 4.4 | 1.2 | 1.9 | 1.42 |
| Aquilino Lopez | Was | mr | 34 | 5 | 1 | 0 | 1 | 2 | 1 | 1 | 3 | 10.2 | 1.2 | 11.5 | 6.8 | 1.0 | 5.9 | 1.26 |
| Javier Lopez* | Tex | mr | 31 | 1 | 0 | 4 | 3 | 1 | 0 | 1 | 2 | 7.8 | 3.4 | 11.6 | 6.4 | 0.5 | 1.9 | 1.25 |
| Mark Lowe | Bos | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 12.7 | 8.7 | 21.4 | 4.1 | 0.5 | 0.5 | 2.38 |
| Ryan Madson | NYY | mr | 28 | 1 | 2 | 3 | 6 | 2 | 0 | 1 | 2 | 10.9 | 2.8 | 14.4 | 7.9 | 1.2 | 2.8 | 1.53 |
| Charlie Manning* | LAA | mr | 30 | 3 | 0 | 1 | 0 | 4 | 0 | 1 | 0 | 8.2 | 8.0 | 16.2 | 8.4 | 2.2 | 1.1 | 1.80 |
| Carlos Marmol | Bal | mr | 26 | 3 | 1 | 0 | 3 | 1 | 0 | 1 | 4 | 5.0 | 5.2 | 10.7 | 12.7 | 0.6 | 2.4 | 1.14 |
| Damaso Marte* | Cle | mr | 34 | 1 | 3 | 0 | 1 | 1 | 0 | 0 | 3 | 9.2 | 5.3 | 14.7 | 11.2 | 0.3 | 2.1 | 1.61 |
| Shairon Martis | KCR | sp | 22 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 7.4 | 5.3 | 12.7 | 11.5 | 2.1 | 2.2 | 1.41 |
| Tom Mastny | Tex | mr | 28 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 11.3 | 4.4 | 16.1 | 6.1 | 3.0 | 1.4 | 1.74 |
| Doug Mathis | Tor | sp | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 15.0 | 3.0 | 18.0 | 4.5 | 3.0 | 1.5 | 2.00 |
| Daisuke Matsuzaka | NYY | sp | 28 | 8 | 8 | 2 | 7 | 4 | 0 | 0 | 9 | 6.4 | 5.3 | 12.0 | 8.3 | 0.4 | 1.6 | 1.30 |
| Kyle McClellan | Bal | mr | 25 | 2 | 1 | 2 | 3 | 12 | 0 | 0 | 6 | 9.0 | 4.0 | 13.3 | 7.2 | 1.0 | 1.8 | 1.44 |
| Dustin McGowan | Cle | sp | 27 | 16 | 5 | 3 | 7 | 6 | 0 | 4 | 3 | 11.0 | 2.9 | 14.4 | 8.4 | 0.8 | 2.8 | 1.54 |
| Gil Meche | KCR | sp | 30 | 8 | 2 | 1 | 2 | 9 | 0 | 3 | 2 | 8.0 | 3.6 | 11.7 | 9.0 | 0.8 | 2.5 | 1.30 |
| Andrew Miller* | LAA | sp | 24 | 5 | 3 | 4 | 5 | 3 | 0 | 2 | 7 | 10.7 | 3.9 | 15.0 | 7.8 | 0.2 | 2.0 | 1.63 |
| Jim Miller | Bos | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.9 | 0.0 | 3.9 | 11.6 | 0.0 | 99.0 | 0.43 |
| Trever Miller* | Tor | mr | 36 | 2 | 1 | 0 | 2 | 2 | 0 | 0 | 1 | 9.8 | 5.5 | 15.8 | 7.9 | 0.5 | 1.5 | 1.70 |
| Kevin Millwood | Mtl | sp | 34 | 13 | 4 | 1 | 8 | 0 | 3 | 4 | 3 | 10.9 | 2.6 | 13.8 | 5.8 | 1.0 | 2.3 | 1.49 |
| Zach Miner | Det | mr | 27 | 4 | 2 | 3 | 5 | 0 | 0 | 0 | 2 | 7.5 | 2.3 | 10.3 | 5.0 | 0.5 | 2.2 | 1.09 |
| Brian Moehler | Tex | sp | 37 | 9 | 7 | 5 | 2 | 2 | 0 | 4 | 15 | 10.8 | 2.2 | 13.0 | 4.5 | 1.3 | 2.1 | 1.44 |
| Brandon Morrow | Was | mr | 24 | 4 | 2 | 1 | 2 | 3 | 0 | 1 | 3 | 5.0 | 3.6 | 8.8 | 9.8 | 1.0 | 2.8 | 0.95 |
| Charlie Morton | Det | sp | 25 | 2 | 1 | 2 | 1 | 4 | 0 | 0 | 3 | 12.4 | 6.0 | 18.6 | 4.1 | 1.3 | 0.7 | 2.05 |
| Guillermo Mota |   | mr | 35 | 5 | 2 | 2 | 1 | 6 | 2 | 2 | 5 | 8.3 | 4.7 | 13.2 | 7.4 | 0.9 | 1.6 | 1.45 |
| Jason Motte | Was | mr | 27 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 8.5 | 4.3 | 12.8 | 6.4 | 0.0 | 1.5 | 1.42 |
| Edward Mujica | Min | mr | 25 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 3 | 11.9 | 2.2 | 14.4 | 5.8 | 0.7 | 2.7 | 1.56 |
| Mike Mussina | Bos | sp | 40 | 11 | 5 | 0 | 13 | 5 | 0 | 5 | 5 | 10.0 | 1.4 | 11.9 | 6.6 | 0.3 | 4.9 | 1.26 |
| Brett Myers | Oak | sp | 28 | 7 | 1 | 1 | 2 | 0 | 0 | 5 | 9 | 8.2 | 3.0 | 11.4 | 7.4 | 1.0 | 2.4 | 1.25 |
| Joe Nelson | Bos | mr | 34 | 7 | 2 | 2 | 1 | 6 | 0 | 0 | 3 | 6.6 | 3.3 | 10.0 | 11.1 | 0.4 | 3.4 | 1.10 |
| Jonathon Niese* | ChW | sp | 22 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 16.6 | 4.5 | 21.1 | 6.4 | 1.9 | 1.4 | 2.35 |
| Fernando Nieve | Bos | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 19.3 | 15.4 | 34.7 | 0.0 | 3.9 | 0.0 | 3.86 |
| Dustin Nippert | ChW | mr | 28 | 3 | 1 | 1 | 3 | 0 | 2 | 0 | 1 | 10.8 | 3.4 | 14.5 | 7.6 | 1.4 | 2.2 | 1.58 |
| Hideki Okajima* | Was | mr | 33 | 3 | 0 | 2 | 1 | 4 | 0 | 1 | 3 | 7.4 | 5.1 | 12.7 | 7.6 | 0.9 | 1.5 | 1.39 |
| Darren Oliver* | Oak | mr | 38 | 2 | 1 | 0 | 2 | 0 | 0 | 0 | 3 | 8.4 | 1.1 | 9.7 | 6.8 | 0.4 | 6.3 | 1.05 |
| Garrett Olson* | LAA | sp | 25 | 16 | 0 | 1 | 2 | 1 | 0 | 5 | 8 | 10.4 | 3.8 | 14.3 | 7.4 | 0.9 | 2.0 | 1.57 |
| Vicente Padilla | KCR | sp | 31 | 3 | 4 | 5 | 21 | 10 | 3 | 1 | 4 | 9.1 | 3.4 | 13.5 | 7.6 | 1.1 | 2.2 | 1.39 |
| Matt Palmer | Tor | sp | 30 | 3 | 0 | 0 | 1 | 2 | 0 | 0 | 1 | 18.7 | 10.4 | 31.2 | 0.0 | 0.0 | 0.0 | 3.23 |
| Jonathan Papelbon | Min | cl | 28 | 3 | 0 | 2 | 3 | 3 | 0 | 0 | 0 | 7.2 | 1.4 | 8.9 | 9.5 | 0.6 | 6.7 | 0.96 |
| Manny Parra* | NYY | sp | 26 | 5 | 3 | 5 | 4 | 17 | 3 | 3 | 2 | 11.4 | 4.9 | 16.5 | 7.9 | 1.6 | 1.6 | 1.81 |
| John Parrish* | Mtl | mr | 31 | 0 | 2 | 1 | 0 | 4 | 0 | 0 | 0 | 9.2 | 6.6 | 15.8 | 4.6 | 0.3 | 0.7 | 1.76 |
| Scott Patterson | Cle | mr | 30 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 37.8 | 16.2 | 54.0 | 5.4 | 0.0 | 0.3 | 6.00 |
| Carl Pavano | Cle | sp | 33 | 2 | 0 | 2 | 3 | 3 | 1 | 0 | 3 | 12.0 | 4.0 | 16.6 | 6.4 | 1.0 | 1.6 | 1.78 |
| Jake Peavy | Oak | sp | 28 | 10 | 7 | 0 | 5 | 1 | 0 | 4 | 4 | 9.0 | 2.9 | 12.1 | 8.9 | 1.0 | 3.1 | 1.32 |
| Tony Pena | Oak | mr | 27 | 0 | 0 | 2 | 2 | 2 | 0 | 4 | 1 | 9.4 | 2.4 | 12.0 | 7.1 | 0.3 | 3.0 | 1.31 |
| Joel Peralta | Tex | mr | 33 | 2 | 1 | 2 | 1 | 0 | 0 | 1 | 1 | 9.0 | 2.8 | 11.9 | 6.9 | 2.6 | 2.5 | 1.31 |
| Troy Percival | LAA | cl | 39 | 6 | 2 | 2 | 1 | 1 | 0 | 1 | 5 | 6.2 | 4.2 | 10.6 | 7.8 | 2.9 | 1.9 | 1.16 |
| Chris Perez | Mtl | mr | 23 | 3 | 1 | 3 | 1 | 0 | 0 | 0 | 3 | 8.3 | 6.8 | 15.3 | 8.6 | 0.3 | 1.3 | 1.67 |
| Odalis Perez* | Tor | sp | 32 | 8 | 6 | 11 | 9 | 4 | 4 | 3 | 4 | 12.0 | 3.5 | 16.0 | 6.1 | 1.1 | 1.8 | 1.72 |
| Oliver Perez* | LAA | sp | 27 | 3 | 4 | 3 | 3 | 2 | 3 | 3 | 5 | 11.1 | 5.0 | 16.5 | 7.6 | 0.6 | 1.5 | 1.80 |
| Glen Perkins* | Oak | sp | 26 | 4 | 4 | 2 | 6 | 4 | 1 | 3 | 7 | 10.4 | 2.4 | 13.1 | 5.2 | 1.2 | 2.2 | 1.42 |
| Scott Proctor | Mtl | mr | 32 | 1 | 3 | 1 | 2 | 5 | 0 | 0 | 1 | 8.0 | 4.8 | 13.3 | 9.8 | 1.5 | 2.1 | 1.42 |
| David Purcey* | ChW | sp | 27 | 4 | 1 | 0 | 1 | 2 | 0 | 2 | 8 | 10.3 | 3.4 | 13.8 | 8.8 | 1.5 | 2.6 | 1.52 |
| Horacio Ramirez* |   | mr | 29 | 3 | 1 | 0 | 7 | 2 | 1 | 1 | 3 | 10.1 | 2.4 | 13.8 | 4.0 | 0.2 | 1.7 | 1.39 |
| Ramon Ramirez | Oak | mr | 27 | 11 | 1 | 1 | 2 | 5 | 1 | 2 | 4 | 5.8 | 3.2 | 9.2 | 8.7 | 0.1 | 2.7 | 1.00 |
| Ramon Ramirez | Det | sp | 26 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.2 | 4.2 | 8.4 | 9.0 | 1.2 | 2.1 | 0.93 |
| Tim Redding | Was | sp | 31 | 12 | 6 | 1 | 4 | 9 | 0 | 3 | 5 | 9.7 | 4.0 | 13.8 | 6.2 | 1.2 | 1.6 | 1.52 |
| Mark Redman* | Sea | sp | 35 | 0 | 0 | 2 | 1 | 3 | 0 | 0 | 3 | 12.6 | 3.7 | 16.4 | 3.8 | 2.0 | 1.0 | 1.81 |
| Chris Resop | Cle | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11.6 | 3.9 | 15.4 | 7.7 | 1.9 | 2.0 | 1.71 |
| Anthony Reyes | Cle | sp | 27 | 2 | 2 | 0 | 2 | 1 | 0 | 1 | 2 | 11.0 | 3.2 | 14.4 | 5.5 | 0.9 | 1.7 | 1.57 |
| Clayton Richard* | Tex | sp | 25 | 9 | 0 | 4 | 2 | 1 | 2 | 2 | 7 | 10.4 | 2.5 | 13.1 | 6.1 | 0.9 | 2.4 | 1.43 |
| Scott Richmond | Min | sp | 29 | 2 | 0 | 4 | 6 | 0 | 0 | 0 | 2 | 10.5 | 1.4 | 13.4 | 6.0 | 0.7 | 4.2 | 1.33 |
| Juan Rincon | Sea | mr | 30 | 2 | 0 | 6 | 6 | 9 | 0 | 3 | 3 | 12.0 | 4.2 | 16.9 | 7.6 | 1.6 | 1.8 | 1.81 |
| Francisco Rodriguez | Tor | cl | 27 | 3 | 0 | 1 | 3 | 11 | 0 | 1 | 2 | 7.1 | 4.7 | 12.1 | 8.7 | 0.5 | 1.9 | 1.31 |
| Kenny Rogers* | Tex | sp | 44 | 5 | 3 | 4 | 6 | 4 | 0 | 2 | 6 | 10.9 | 3.6 | 14.8 | 4.7 | 1.2 | 1.3 | 1.61 |
| J.C. Romero* | Det | mr | 33 | 6 | 3 | 9 | 5 | 4 | 1 | 1 | 4 | 5.7 | 6.7 | 13.0 | 8.6 | 0.8 | 1.3 | 1.38 |
| Sergio Romo | Min | mr | 26 | 3 | 2 | 1 | 4 | 1 | 1 | 2 | 0 | 5.2 | 3.0 | 9.1 | 7.8 | 1.1 | 2.6 | 0.92 |
| Carlos Rosa | KCR | mr | 24 | 1 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 11.7 | 5.9 | 17.6 | 5.9 | 1.2 | 1.0 | 1.96 |
| Leo Rosales | Tor | mr | 28 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 108.0 | 54.0 | 162.0 | 0.0 | 0.0 | 0.0 | 18.00 |
| Josh Rupe | ChW | mr | 26 | 2 | 3 | 2 | 11 | 5 | 0 | 3 | 3 | 8.6 | 5.1 | 14.7 | 4.9 | 1.1 | 1.0 | 1.52 |
| B.J. Ryan* |   | cl | 33 | 5 | 1 | 1 | 2 | 4 | 3 | 3 | 4 | 6.5 | 4.2 | 10.9 | 8.4 | 0.4 | 2.0 | 1.19 |
| C.C. Sabathia* | Oak | sp | 28 | 14 | 7 | 3 | 10 | 1 | 1 | 5 | 6 | 9.4 | 2.0 | 11.7 | 9.3 | 1.1 | 4.7 | 1.26 |
| Jeff Samardzija | ChW | mr | 24 | 5 | 0 | 0 | 6 | 5 | 1 | 1 | 2 | 9.8 | 6.0 | 17.3 | 6.5 | 0.8 | 1.1 | 1.75 |
| Chris Sampson | NYY | mr | 31 | 4 | 1 | 2 | 4 | 0 | 0 | 6 | 2 | 9.2 | 1.7 | 11.2 | 3.7 | 0.6 | 2.2 | 1.22 |
| Duaner Sanchez | Bos | mr | 29 | 0 | 2 | 0 | 2 | 1 | 0 | 3 | 3 | 9.0 | 4.2 | 13.5 | 5.7 | 0.9 | 1.4 | 1.46 |
| Johan Santana* | Sea | sp | 30 | 5 | 5 | 5 | 8 | 6 | 0 | 1 | 7 | 8.2 | 3.1 | 11.6 | 7.7 | 1.0 | 2.5 | 1.25 |
| Joe Saunders* | LAA | sp | 28 | 16 | 4 | 1 | 6 | 4 | 0 | 1 | 9 | 8.4 | 2.0 | 10.6 | 5.0 | 0.8 | 2.6 | 1.15 |
| Max Scherzer | Tor | mr | 24 | 0 | 0 | 1 | 6 | 2 | 0 | 0 | 3 | 7.7 | 5.3 | 13.7 | 9.1 | 0.5 | 1.7 | 1.45 |
| Scott Schoeneweis* | Det | mr | 35 | 1 | 0 | 6 | 2 | 4 | 0 | 2 | 7 | 11.0 | 4.6 | 15.8 | 5.9 | 1.2 | 1.3 | 1.72 |
| Bobby Seay* | Bal | mr | 31 | 2 | 3 | 0 | 0 | 6 | 0 | 2 | 2 | 10.6 | 3.1 | 13.6 | 10.4 | 0.7 | 3.4 | 1.52 |
| Ben Sheets | Oak | sp | 30 | 24 | 4 | 1 | 1 | 17 | 0 | 6 | 10 | 9.4 | 2.9 | 12.3 | 7.8 | 0.7 | 2.7 | 1.37 |
| George Sherrill* | KCR | cl | 32 | 2 | 0 | 7 | 1 | 2 | 0 | 2 | 9 | 7.8 | 4.6 | 12.5 | 10.6 | 1.1 | 2.3 | 1.38 |
| Scot Shields | Min | mr | 33 | 3 | 2 | 1 | 3 | 1 | 0 | 3 | 4 | 7.4 | 3.0 | 10.7 | 8.4 | 0.8 | 2.8 | 1.16 |
| Kevin Slowey | Tor | sp | 25 | 3 | 2 | 13 | 1 | 1 | 0 | 2 | 8 | 9.1 | 2.0 | 11.1 | 6.3 | 0.9 | 3.2 | 1.23 |
| Greg Smith* | Det | sp | 25 | 9 | 4 | 5 | 2 | 6 | 0 | 4 | 5 | 7.6 | 3.9 | 11.5 | 4.9 | 1.4 | 1.3 | 1.27 |
| Joe Smith | Tor | mr | 25 | 4 | 2 | 9 | 4 | 0 | 0 | 1 | 2 | 7.8 | 5.8 | 14.0 | 6.5 | 0.4 | 1.1 | 1.51 |
| John Smoltz | Mtl | sp | 42 | 5 | 0 | 1 | 0 | 2 | 0 | 1 | 3 | 9.5 | 2.5 | 12.0 | 10.6 | 0.9 | 4.2 | 1.33 |
| Ian Snell | Tex | sp | 27 | 2 | 2 | 0 | 1 | 1 | 0 | 0 | 2 | 14.6 | 4.1 | 19.1 | 5.6 | 1.1 | 1.4 | 2.08 |
| Rafael Soriano | Min | mr | 29 | 1 | 0 | 3 | 0 | 0 | 0 | 0 | 2 | 8.7 | 15.7 | 24.4 | 14.8 | 0.9 | 0.9 | 2.71 |
| Jeremy Sowers* | Det | sp | 26 | 11 | 4 | 5 | 2 | 0 | 0 | 1 | 1 | 8.3 | 3.1 | 11.5 | 4.8 | 0.6 | 1.6 | 1.26 |
| Justin Speier | NYY | mr | 35 | 3 | 1 | 3 | 3 | 10 | 0 | 1 | 9 | 7.2 | 2.8 | 10.4 | 7.2 | 1.5 | 2.5 | 1.11 |
| Russ Springer | Min | mr | 40 | 7 | 0 | 3 | 1 | 2 | 0 | 2 | 4 | 9.1 | 4.1 | 13.4 | 9.3 | 1.5 | 2.2 | 1.47 |
| Mitch Stetter* | Was | mr | 28 | 3 | 1 | 2 | 3 | 0 | 0 | 1 | 2 | 8.4 | 7.8 | 17.2 | 12.5 | 0.3 | 1.6 | 1.80 |
| Brian Stokes | Was | mr | 29 | 2 | 0 | 0 | 1 | 3 | 0 | 0 | 0 | 12.0 | 1.4 | 13.6 | 7.6 | 0.0 | 5.6 | 1.48 |
| Huston Street | NYY | cl | 25 | 4 | 2 | 6 | 2 | 3 | 0 | 1 | 5 | 7.5 | 4.3 | 12.0 | 8.9 | 0.7 | 2.1 | 1.31 |
| Jeff Suppan | Bal | sp | 34 | 5 | 3 | 2 | 8 | 2 | 2 | 4 | 7 | 12.0 | 3.3 | 15.7 | 4.6 | 1.3 | 1.4 | 1.70 |
| Jack Taschner* | NYY | mr | 31 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 12.0 | 4.5 | 16.5 | 7.5 | 1.5 | 1.7 | 1.83 |
| Brad Thompson | KCR | mr | 27 | 3 | 1 | 2 | 3 | 6 | 0 | 2 | 4 | 12.5 | 3.4 | 16.3 | 4.2 | 1.4 | 1.2 | 1.77 |
| Rich Thompson | Mtl | mr | 24 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 9.8 | 2.5 | 12.3 | 4.9 | 0.0 | 2.0 | 1.36 |
| Ramon Troncoso | Tex | mr | 26 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 9.9 | 1.8 | 11.7 | 10.8 | 0.9 | 6.0 | 1.30 |
| Justin Verlander | Cle | sp | 26 | 6 | 3 | 0 | 9 | 10 | 5 | 3 | 9 | 8.7 | 3.3 | 12.4 | 7.9 | 0.8 | 2.4 | 1.33 |
| Edinson Volquez | Mtl | sp | 25 | 11 | 3 | 1 | 15 | 7 | 0 | 2 | 4 | 8.6 | 4.8 | 14.2 | 9.5 | 0.9 | 2.0 | 1.49 |
| Chris Volstad | KCR | sp | 22 | 9 | 8 | 0 | 6 | 0 | 0 | 3 | 6 | 8.7 | 3.6 | 12.8 | 4.4 | 0.4 | 1.2 | 1.37 |
| Doug Waechter | ChW | mr | 28 | 4 | 1 | 2 | 2 | 2 | 0 | 0 | 4 | 11.4 | 2.3 | 14.1 | 7.3 | 1.3 | 3.2 | 1.53 |
| Tim Wakefield | Min | sp | 42 | 17 | 4 | 2 | 16 | 14 | 0 | 4 | 3 | 7.3 | 2.9 | 10.8 | 5.5 | 0.9 | 1.9 | 1.13 |
| Jamie Walker* | Bal | mr | 37 | 0 | 2 | 3 | 2 | 1 | 0 | 2 | 2 | 11.0 | 2.2 | 13.6 | 6.3 | 3.0 | 2.8 | 1.47 |
| Tyler Walker | Sea | mr | 33 | 2 | 2 | 5 | 6 | 5 | 0 | 2 | 1 | 7.9 | 3.7 | 12.1 | 9.1 | 1.6 | 2.5 | 1.29 |
| Jarrod Washburn* | Det | sp | 34 | 2 | 2 | 3 | 10 | 2 | 0 | 2 | 6 | 11.2 | 3.8 | 15.7 | 4.4 | 1.5 | 1.2 | 1.67 |
| Chris Waters* | Tor | sp | 28 | 4 | 1 | 0 | 2 | 0 | 0 | 1 | 0 | 8.1 | 3.6 | 12.3 | 6.3 | 0.0 | 1.8 | 1.30 |
| David Weathers | Det | mr | 39 | 3 | 4 | 2 | 3 | 0 | 1 | 2 | 2 | 8.2 | 2.6 | 11.3 | 6.1 | 0.4 | 2.3 | 1.21 |
| Brandon Webb | Det | sp | 30 | 13 | 5 | 5 | 9 | 5 | 1 | 3 | 2 | 9.2 | 2.7 | 12.4 | 7.4 | 0.7 | 2.7 | 1.33 |
| Kip Wells | Tex | mr | 32 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 6.8 | 15.8 | 4.5 | 2.3 | 0.7 | 1.75 |
| Dontrelle Willis* | Was | sp | 27 | 1 | 0 | 2 | 0 | 9 | 1 | 0 | 1 | 5.6 | 8.5 | 14.1 | 6.4 | 1.1 | 0.8 | 1.57 |
| C.J. Wilson* | KCR | cl | 28 | 1 | 1 | 3 | 1 | 5 | 0 | 2 | 2 | 8.2 | 4.8 | 13.2 | 7.4 | 1.0 | 1.5 | 1.45 |
| Randy Wolf* | ChW | sp | 32 | 9 | 8 | 1 | 11 | 3 | 0 | 4 | 8 | 9.9 | 3.5 | 13.9 | 6.5 | 1.0 | 1.9 | 1.49 |
| Brian Wolfe | Mtl | mr | 28 | 2 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 11.3 | 4.7 | 16.0 | 7.8 | 1.9 | 1.7 | 1.78 |
| Kerry Wood | Det | cl | 32 | 3 | 0 | 7 | 5 | 1 | 0 | 2 | 5 | 10.0 | 4.4 | 15.0 | 10.8 | 0.1 | 2.5 | 1.60 |
| Michael Wuertz | Tex | mr | 30 | 3 | 0 | 0 | 0 | 4 | 0 | 1 | 1 | 11.9 | 3.8 | 15.7 | 7.7 | 1.5 | 2.0 | 1.74 |
| Yasuhiko Yabuta | Cle | mr | 36 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.7 | 0.0 | 7.7 | 0.0 | 0.0 | 0.0 | 0.86 |
| Charlie Zink | Cle | sp | 29 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 1 | 10.1 | 3.4 | 13.5 | 5.9 | 0.0 | 1.8 | 1.50 |
| Barry Zito* | ChW | sp | 31 | 12 | 8 | 1 | 7 | 2 | 0 | 0 | 16 | 9.6 | 7.0 | 17.0 | 6.2 | 1.2 | 0.9 | 1.84 |
| Joel Zumaya | KCR | mr | 24 | 4 | 0 | 1 | 0 | 9 | 0 | 0 | 6 | 5.7 | 6.6 | 12.2 | 7.3 | 0.4 | 1.1 | 1.36 |
| Analytical |
| Name | Team | P | Age | OPS | BIP | BABIP | TBW | TBW/BF | TBWH | TBWH/BF | RC | RC27 | RCERA | CERA |
| Alfredo Aceves | Was | sp | 26 | .920 | 57 | .333 | 46 | .582 | 46 | .582 | 15.1 | 8.5 | 7.96 | 7.64 |
| Nick Adenhart | Bal | sp | 22 | .847 | 57 | .351 | 33 | .485 | 34 | .500 | 11.0 | 6.9 | 6.20 | 5.99 |
| Jeremy Affeldt* | Bos | mr | 30 | .639 | 67 | .343 | 46 | .377 | 49 | .402 | 11.4 | 3.6 | 3.27 | 3.42 |
| Jonathan Albaladejo | Min | mr | 26 | 3.000 | 2 | 1.000 | 4 | 2.000 | 4 | 2.000 | 4.0 | 0.0 | 99.00 | 0.00 |
| Matt Albers | Tex | mr | 26 | .623 | 307 | .228 | 161 | .378 | 169 | .397 | 35.8 | 3.1 | 2.82 | 3.09 |
| Jose Arredondo | Cle | mr | 25 | .453 | 170 | .229 | 67 | .271 | 67 | .271 | 11.9 | 1.7 | 1.52 | 1.46 |
| Luis Ayala | Bal | mr | 31 | .805 | 246 | .325 | 160 | .476 | 165 | .491 | 46.3 | 5.5 | 5.09 | 5.22 |
| Brandon Backe | Bal | sp | 31 | .939 | 535 | .364 | 442 | .570 | 449 | .579 | 145.5 | 8.1 | 7.32 | 7.30 |
| Burke Badenhop | KCR | sp | 26 | .800 | 174 | .270 | 133 | .504 | 137 | .519 | 36.4 | 5.5 | 4.94 | 5.45 |
| Cha Seung Baek | NYY | sp | 29 | .947 | 455 | .332 | 372 | .589 | 376 | .595 | 124.8 | 8.6 | 7.67 | 7.20 |
| Homer Bailey | Tor | sp | 23 | .913 | 82 | .354 | 57 | .548 | 57 | .548 | 19.9 | 8.5 | 7.78 | 8.74 |
| Josh Banks | Mtl | sp | 26 | .832 | 430 | .314 | 282 | .503 | 286 | .510 | 86.9 | 6.3 | 5.72 | 5.90 |
| Brian Bass | Bal | mr | 27 | .735 | 230 | .265 | 124 | .444 | 127 | .455 | 32.1 | 4.3 | 3.92 | 3.90 |
| Miguel Batista | Bal | mr | 38 | .942 | 349 | .309 | 295 | .577 | 303 | .593 | 95.4 | 8.1 | 7.40 | 7.59 |
| Denny Bautista | Sea | mr | 28 | .991 | 35 | .371 | 35 | .614 | 35 | .614 | 12.5 | 11.6 | 10.45 | 12.67 |
| T.J. Beam | LAA | mr | 28 | .596 | 50 | .320 | 23 | .343 | 23 | .343 | 5.6 | 3.1 | 2.77 | 2.50 |
| Josh Beckett | KCR | sp | 29 | .686 | 603 | .315 | 362 | .405 | 376 | .421 | 91.0 | 3.8 | 3.48 | 3.62 |
| Joe Beimel* | Min | mr | 32 | .714 | 211 | .308 | 126 | .420 | 130 | .433 | 34.5 | 4.6 | 4.09 | 4.30 |
| Matt Belisle | Tex | sp | 29 | .839 | 49 | .306 | 31 | .508 | 31 | .508 | 9.6 | 6.3 | 5.71 | 5.78 |
| Joaquin Benoit | Oak | mr | 31 | .757 | 16 | .250 | 14 | .519 | 14 | .519 | 3.6 | 6.1 | 5.14 | 4.87 |
| Jason Bergmann | KCR | sp | 27 | .913 | 442 | .312 | 361 | .590 | 362 | .592 | 110.7 | 7.2 | 6.45 | 6.00 |
| Randor Bierd | Mtl | mr | 25 | .964 | 119 | .378 | 91 | .576 | 93 | .589 | 33.5 | 9.4 | 8.49 | 7.24 |
| Jerry Blevins* | Mtl | mr | 25 | .590 | 137 | .255 | 74 | .365 | 75 | .369 | 16.1 | 2.9 | 2.66 | 2.72 |
| Mitchell Boggs | Det | sp | 25 | 1.116 | 55 | .364 | 63 | .700 | 64 | .711 | 22.6 | 11.8 | 11.01 | 11.54 |
| Jeremy Bonderman | Was | sp | 26 | .688 | 180 | .311 | 101 | .396 | 105 | .412 | 26.3 | 4.0 | 3.66 | 4.13 |
| Eddie Bonine | Tex | sp | 28 | .626 | 96 | .281 | 37 | .325 | 40 | .351 | 9.4 | 3.0 | 2.68 | 2.71 |
| Michael Bowden | NYY | sp | 22 | .932 | 87 | .345 | 69 | .590 | 69 | .590 | 22.9 | 8.4 | 8.08 | 7.55 |
| Dallas Braden* | Mtl | sp | 25 | .674 | 384 | .286 | 199 | .396 | 203 | .404 | 50.5 | 3.8 | 3.36 | 3.50 |
| Chad Bradford | Det | mr | 34 | .652 | 348 | .279 | 147 | .359 | 155 | .378 | 37.0 | 3.3 | 3.01 | 3.36 |
| Craig Breslow* | NYY | mr | 28 | .539 | 182 | .258 | 92 | .335 | 92 | .335 | 18.5 | 2.5 | 2.29 | 2.43 |
| Doug Brocail | Tor | mr | 42 | .656 | 307 | .293 | 189 | .394 | 197 | .410 | 47.5 | 3.7 | 3.39 | 2.99 |
| Andrew Brown | Mtl | mr | 28 | .562 | 149 | .208 | 85 | .366 | 86 | .371 | 17.2 | 2.6 | 2.33 | 1.98 |
| Brian Bruney |   | mr | 27 | .517 | 163 | .178 | 98 | .344 | 100 | .351 | 18.5 | 2.3 | 2.01 | 1.62 |
| Clay Buchholz | Cle | sp | 24 | .803 | 310 | .352 | 224 | .483 | 227 | .489 | 68.9 | 6.2 | 5.67 | 5.58 |
| Taylor Buchholz | ChW | mr | 27 | .571 | 30 | .333 | 15 | .313 | 16 | .333 | 3.4 | 2.5 | 2.42 | 2.55 |
| Bryan Bullington | Bos | sp | 28 | .375 | 7 | .143 | 2 | .250 | 2 | .250 | 0.3 | 1.0 | 0.87 | 0.40 |
| Brian Burres* | Tex | sp | 28 | .891 | 601 | .356 | 402 | .528 | 407 | .534 | 135.3 | 7.5 | 6.89 | 6.78 |
| Paul Byrd | Tor | sp | 38 | .782 | 683 | .277 | 403 | .477 | 408 | .483 | 108.8 | 4.9 | 4.46 | 4.61 |
| Daniel Cabrera | Bal | sp | 28 | .803 | 616 | .282 | 415 | .487 | 429 | .504 | 117.7 | 5.6 | 5.05 | 5.48 |
| Matt Cain | NYY | sp | 24 | .790 | 603 | .330 | 428 | .478 | 436 | .487 | 123.4 | 5.6 | 5.04 | 5.07 |
| Shawn Camp | Oak | mr | 33 | .722 | 162 | .340 | 92 | .413 | 95 | .426 | 25.5 | 4.5 | 4.14 | 3.90 |
| Jorge Campillo | Bos | sp | 30 | .828 | 500 | .330 | 367 | .508 | 372 | .515 | 108.7 | 6.0 | 5.46 | 5.23 |
| Matt Capps | Sea | cl | 25 | .689 | 236 | .263 | 125 | .418 | 127 | .425 | 31.5 | 3.8 | 3.43 | 2.95 |
| Vinnie Chulk | Was | mr | 30 | .828 | 42 | .333 | 29 | .518 | 29 | .518 | 9.0 | 6.8 | 6.10 | 5.33 |
| Tyler Clippard | Sea | sp | 24 | 1.263 | 27 | .444 | 31 | .795 | 31 | .795 | 11.4 | 14.0 | 12.56 | 11.53 |
| Todd Coffey | Cle | mr | 28 | .580 | 43 | .163 | 20 | .345 | 22 | .379 | 4.2 | 2.7 | 2.34 | 2.39 |
| Phil Coke* | Bal | mr | 26 | .432 | 45 | .178 | 16 | .271 | 16 | .271 | 2.8 | 1.6 | 1.45 | 1.09 |
| Bartolo Colon | Sea | sp | 36 | .697 | 229 | .306 | 128 | .413 | 130 | .419 | 34.4 | 4.2 | 3.87 | 3.87 |
| Francisco Cordero | Tex | cl | 34 | .632 | 159 | .302 | 105 | .385 | 107 | .392 | 25.1 | 3.5 | 3.27 | 3.57 |
| Lance Cormier | Oak | mr | 28 | .705 | 313 | .288 | 181 | .427 | 183 | .432 | 46.8 | 4.3 | 3.92 | 4.27 |
| Manuel Corpas | NYY | mr | 26 | .878 | 264 | .348 | 189 | .526 | 192 | .535 | 57.7 | 6.5 | 5.86 | 6.33 |
| Kevin Correia | Sea | sp | 28 | .849 | 388 | .340 | 246 | .496 | 253 | .510 | 78.3 | 6.6 | 5.87 | 6.29 |
| Juan Cruz | Cle | mr | 30 | .696 | 156 | .282 | 137 | .461 | 137 | .461 | 33.0 | 4.5 | 4.16 | 4.38 |
| Johnny Cueto | Sea | sp | 23 | .767 | 550 | .315 | 396 | .473 | 403 | .481 | 109.5 | 5.2 | 4.77 | 4.91 |
| Eulogio De La Cruz | ChW | mr | 25 | .991 | 38 | .263 | 38 | .644 | 38 | .644 | 11.1 | 8.6 | 7.73 | 9.72 |
| Jorge De La Rosa* | Was | sp | 28 | .733 | 438 | .324 | 323 | .450 | 328 | .457 | 84.4 | 4.6 | 4.11 | 4.22 |
| Manny Delcarmen | Cle | mr | 27 | .514 | 154 | .227 | 69 | .309 | 71 | .318 | 13.9 | 2.2 | 1.94 | 1.59 |
| Ryan Dempster | LAA | sp | 32 | .643 | 624 | .279 | 353 | .390 | 362 | .400 | 84.2 | 3.5 | 3.14 | 3.14 |
| Joey Devine | Bos | mr | 25 | .414 | 247 | .215 | 96 | .252 | 97 | .255 | 15.6 | 1.4 | 1.23 | 1.08 |
| R.A. Dickey | Min | mr | 34 | .679 | 323 | .276 | 184 | .417 | 185 | .420 | 47.9 | 4.2 | 3.82 | 3.70 |
| Mark DiFelice | Bos | mr | 32 | .939 | 50 | .360 | 53 | .602 | 53 | .602 | 18.0 | 8.8 | 8.56 | 8.67 |
| Tim Dillard | Min | mr | 25 | 2.167 | 2 | .500 | 8 | 1.333 | 8 | 1.333 | 3.5 | 31.7 | 28.51 | 34.22 |
| Octavio Dotel | Mtl | mr | 35 | .774 | 165 | .273 | 152 | .502 | 155 | .512 | 37.3 | 4.5 | 4.09 | 3.98 |
| Scott Downs* | LAA | mr | 33 | .562 | 276 | .246 | 131 | .338 | 134 | .345 | 27.5 | 2.5 | 2.31 | 2.22 |
| Justin Duchscherer | Cle | sp | 31 | .537 | 552 | .228 | 228 | .317 | 237 | .329 | 46.3 | 2.2 | 2.00 | 1.69 |
| Zach Duke* | Tor | sp | 26 | .866 | 301 | .365 | 192 | .500 | 198 | .516 | 65.0 | 7.2 | 6.40 | 6.10 |
| Chad Durbin | KCR | mr | 31 | .676 | 302 | .275 | 166 | .403 | 169 | .410 | 39.3 | 3.6 | 3.20 | 3.53 |
| Adam Eaton | Bal | sp | 31 | .888 | 465 | .329 | 319 | .532 | 326 | .543 | 97.6 | 6.6 | 5.99 | 6.65 |
| Scott Elarton | LAA | mr | 33 | .778 | 6 | .167 | 5 | .556 | 5 | .556 | 1.1 | 4.3 | 4.50 | 4.12 |
| Alan Embree* | Sea | mr | 39 | .723 | 288 | .292 | 213 | .451 | 216 | .458 | 52.3 | 4.2 | 3.82 | 4.16 |
| Shawn Estes* | Sea | sp | 36 | .829 | 236 | .288 | 149 | .505 | 151 | .512 | 44.1 | 6.2 | 5.59 | 6.13 |
| Dana Eveland* | LAA | sp | 25 | .686 | 529 | .287 | 315 | .409 | 328 | .425 | 78.8 | 3.9 | 3.52 | 3.79 |
| Scott Eyre* | LAA | mr | 37 | .636 | 98 | .224 | 66 | .412 | 69 | .431 | 12.6 | 2.7 | 2.41 | 2.14 |
| Kyle Farnsworth | Mtl | mr | 33 | .975 | 67 | .388 | 68 | .624 | 68 | .624 | 22.3 | 8.6 | 7.75 | 8.21 |
| Ryan Feierabend* | ChW | sp | 23 | 1.038 | 328 | .375 | 284 | .640 | 284 | .640 | 99.8 | 10.0 | 8.91 | 8.84 |
| Pedro Feliciano* | NYY | mr | 32 | .712 | 208 | .341 | 126 | .421 | 128 | .428 | 34.3 | 4.4 | 4.00 | 4.12 |
| Nelson Figueroa | KCR | mr | 35 | 1.053 | 89 | .461 | 78 | .614 | 78 | .614 | 28.9 | 11.3 | 10.03 | 11.43 |
| Keith Foulke | Was | mr | 36 | .725 | 16 | .313 | 10 | .435 | 10 | .435 | 3.2 | 6.1 | 5.91 | 5.80 |
| Jeff Francis* | ChW | sp | 28 | .833 | 580 | .334 | 393 | .506 | 398 | .512 | 122.4 | 6.4 | 5.76 | 5.31 |
| Ryan Franklin | Det | mr | 36 | .961 | 198 | .354 | 156 | .586 | 158 | .594 | 52.5 | 8.6 | 7.64 | 7.32 |
| Eric Gagne | Tor | mr | 33 | .727 | 131 | .237 | 88 | .466 | 91 | .481 | 20.9 | 4.2 | 3.74 | 3.67 |
| Freddy Garcia | Min | sp | 33 | .704 | 107 | .215 | 72 | .459 | 74 | .471 | 17.4 | 4.0 | 3.67 | 3.48 |
| Jaime Garcia* | Sea | mr | 22 | .856 | 102 | .294 | 84 | .535 | 86 | .548 | 24.8 | 6.6 | 6.15 | 6.83 |
| Jon Garland | Mtl | sp | 29 | .864 | 637 | .317 | 425 | .523 | 433 | .533 | 125.9 | 6.2 | 5.56 | 5.81 |
| Matt Garza | Bal | sp | 25 | .751 | 580 | .284 | 385 | .466 | 390 | .472 | 99.9 | 4.5 | 4.08 | 4.10 |
| Geoff Geary | LAA | mr | 32 | .580 | 230 | .235 | 110 | .356 | 112 | .362 | 23.7 | 2.7 | 2.47 | 2.26 |
| Josh Geer | ChW | sp | 26 | .756 | 185 | .303 | 110 | .458 | 111 | .463 | 31.6 | 5.2 | 4.76 | 4.54 |
| Franklyn German | Min | mr | 29 | .717 | 59 | .356 | 37 | .425 | 37 | .425 | 9.4 | 4.5 | 4.15 | 5.51 |
| Justin Germano | Tex | sp | 26 | .892 | 121 | .347 | 80 | .530 | 82 | .543 | 25.6 | 6.8 | 6.21 | 6.61 |
| Matt Ginter | Min | sp | 31 | .645 | 49 | .306 | 23 | .383 | 23 | .383 | 5.5 | 3.3 | 2.85 | 2.35 |
| Gary Glover | Tor | mr | 32 | .770 | 289 | .322 | 181 | .465 | 183 | .470 | 51.9 | 5.3 | 4.77 | 4.54 |
| Jimmy Gobble* | Tor | mr | 27 | 1.112 | 28 | .393 | 30 | .698 | 30 | .698 | 11.7 | 13.7 | 10.92 | 9.26 |
| Edgar Gonzalez | LAA | mr | 26 | .429 | 5 | .200 | 2 | .286 | 2 | .286 | 0.3 | 1.3 | 1.16 | 0.54 |
| Gio Gonzalez* | Sea | sp | 23 | .907 | 148 | .264 | 162 | .602 | 163 | .606 | 46.0 | 7.3 | 6.58 | 6.86 |
| Mike Gonzalez* | Cle | cl | 31 | .710 | 60 | .383 | 51 | .447 | 52 | .456 | 13.9 | 4.6 | 4.16 | 3.33 |
| Tom Gorzelanny* | Sea | sp | 26 | .860 | 415 | .296 | 323 | .535 | 328 | .543 | 93.7 | 6.5 | 5.87 | 6.41 |
| Sean Green | ChW | mr | 30 | .655 | 268 | .299 | 148 | .394 | 150 | .399 | 36.1 | 3.6 | 3.32 | 3.51 |
| Zack Greinke | Bos | sp | 25 | .692 | 634 | .312 | 377 | .419 | 381 | .423 | 96.7 | 4.0 | 3.59 | 3.22 |
| Matt Guerrier | Cle | mr | 30 | .827 | 193 | .373 | 141 | .500 | 142 | .504 | 44.4 | 6.7 | 5.99 | 5.95 |
| Charlie Haeger | Cle | mr | 25 | 1.040 | 9 | .444 | 15 | .600 | 17 | .680 | 5.9 | 11.3 | 10.94 | 12.59 |
| Jason Hammel | ChW | mr | 26 | .748 | 287 | .244 | 182 | .475 | 183 | .478 | 45.8 | 4.5 | 4.06 | 4.03 |
| Mike Hampton* | Cle | sp | 36 | .871 | 288 | .285 | 206 | .563 | 206 | .563 | 57.2 | 6.0 | 5.51 | 5.14 |
| Joel Hanrahan | Tex | mr | 27 | .623 | 320 | .291 | 202 | .383 | 207 | .393 | 47.9 | 3.4 | 3.09 | 2.83 |
| J.A. Happ* | LAA | sp | 26 | .672 | 70 | .329 | 44 | .404 | 44 | .404 | 11.4 | 4.3 | 3.91 | 4.56 |
| Aaron Harang | Tor | sp | 31 | .797 | 588 | .301 | 411 | .504 | 413 | .507 | 117.4 | 5.6 | 5.05 | 4.51 |
| Aaron Heilman | Tor | mr | 30 | .691 | 96 | .344 | 74 | .428 | 75 | .434 | 19.1 | 4.6 | 4.30 | 4.52 |
| Mark Hendrickson* | Was | sp | 35 | .744 | 451 | .299 | 267 | .448 | 270 | .453 | 74.2 | 4.8 | 4.30 | 4.13 |
| Clay Hensley | Was | mr | 29 | .674 | 111 | .243 | 68 | .433 | 69 | .439 | 15.2 | 3.6 | 3.36 | 3.23 |
| Felix Hernandez | Min | sp | 23 | .748 | 629 | .328 | 420 | .448 | 431 | .460 | 115.4 | 4.9 | 4.38 | 4.62 |
| Alex Hinshaw* | NYY | mr | 26 | .953 | 50 | .420 | 53 | .576 | 54 | .587 | 18.1 | 8.9 | 8.29 | 9.65 |
| Luke Hochevar | NYY | sp | 25 | .773 | 507 | .272 | 329 | .482 | 335 | .490 | 86.1 | 4.8 | 4.26 | 4.43 |
| J.P. Howell* | Bos | mr | 26 | .684 | 189 | .286 | 131 | .432 | 134 | .442 | 33.4 | 4.3 | 3.94 | 3.56 |
| Tim Hudson | Det | sp | 33 | .708 | 299 | .268 | 177 | .441 | 179 | .446 | 42.3 | 4.0 | 3.57 | 3.50 |
| Jason Isringhausen | Oak | cl | 36 | 1.056 | 9 | .444 | 7 | .583 | 7 | .583 | 3.3 | 14.8 | 13.28 | 12.01 |
| Edwin Jackson | Min | sp | 25 | .793 | 551 | .310 | 367 | .486 | 370 | .490 | 105.2 | 5.5 | 5.01 | 4.95 |
| Zach Jackson* | ChW | sp | 26 | .752 | 199 | .327 | 116 | .439 | 120 | .455 | 33.3 | 4.9 | 4.50 | 4.31 |
| Chuck James* | Sea | sp | 27 | .867 | 75 | .373 | 59 | .504 | 63 | .538 | 19.8 | 7.4 | 6.77 | 7.13 |
| Bobby Jenks | KCR | cl | 28 | .538 | 210 | .243 | 84 | .313 | 86 | .321 | 16.9 | 2.2 | 2.00 | 1.78 |
| Jason Johnson | Was | mr | 35 | .869 | 83 | .313 | 54 | .505 | 58 | .542 | 16.1 | 5.9 | 5.21 | 5.09 |
| Josh Johnson | Min | sp | 25 | .755 | 346 | .350 | 226 | .450 | 228 | .454 | 60.5 | 4.7 | 4.20 | 4.66 |
| Todd Jones | Mtl | cl | 41 | .665 | 79 | .266 | 40 | .392 | 41 | .402 | 10.1 | 3.7 | 3.39 | 3.63 |
| Jorge Julio | Oak | mr | 30 | .779 | 78 | .359 | 80 | .510 | 80 | .510 | 20.1 | 5.0 | 4.45 | 4.28 |
| Jair Jurrjens | Mtl | sp | 23 | .770 | 624 | .345 | 384 | .454 | 390 | .462 | 108.0 | 5.0 | 4.51 | 4.58 |
| Scott Kazmir* | Bos | sp | 25 | .687 | 439 | .267 | 334 | .443 | 341 | .452 | 80.4 | 4.0 | 3.67 | 3.50 |
| Kyle Kendrick | Det | sp | 24 | .810 | 468 | .318 | 288 | .474 | 301 | .496 | 88.9 | 6.0 | 5.35 | 4.97 |
| Logan Kensing | Was | mr | 26 | .725 | 162 | .278 | 115 | .451 | 118 | .463 | 30.3 | 4.7 | 4.23 | 4.45 |
| Masa Kobayashi | Bal | mr | 35 | .668 | 213 | .277 | 111 | .410 | 111 | .410 | 27.2 | 3.7 | 3.31 | 3.02 |
| Eddie Kunz | ChW | mr | 23 | .640 | 21 | .238 | 9 | .237 | 17 | .447 | 2.8 | 3.0 | 2.70 | 5.39 |
| Hong-Chih Kuo* | Bos | mr | 27 | .626 | 289 | .315 | 184 | .391 | 185 | .394 | 41.9 | 3.2 | 2.91 | 2.35 |
| John Lackey | Cle | sp | 30 | .755 | 573 | .298 | 361 | .460 | 368 | .469 | 94.7 | 4.5 | 4.13 | 4.38 |
| John Lannan* | Was | sp | 24 | .791 | 568 | .287 | 395 | .487 | 405 | .499 | 109.1 | 5.4 | 4.93 | 5.21 |
| Brandon League | Min | mr | 26 | .692 | 145 | .310 | 81 | .407 | 83 | .417 | 21.0 | 4.0 | 3.67 | 3.58 |
| Wil Ledezma* | Was | mr | 28 | .809 | 133 | .271 | 122 | .515 | 125 | .527 | 37.1 | 6.9 | 6.26 | 6.41 |
| Jensen Lewis | Cle | cl | 25 | .760 | 231 | .312 | 153 | .442 | 160 | .462 | 44.1 | 5.2 | 4.58 | 4.90 |
| Brad Lidge | ChW | cl | 32 | .838 | 18 | .389 | 19 | .543 | 19 | .543 | 5.4 | 6.4 | 5.73 | 5.62 |
| Mike Lincoln | Sea | mr | 34 | .731 | 325 | .295 | 216 | .441 | 223 | .455 | 59.7 | 4.7 | 4.23 | 4.21 |
| Scott Linebrink | LAA | mr | 32 | .512 | 169 | .249 | 76 | .302 | 78 | .310 | 15.7 | 2.2 | 1.97 | 1.85 |
| Francisco Liriano* | Min | sp | 25 | .710 | 297 | .269 | 205 | .446 | 210 | .457 | 50.5 | 4.2 | 3.76 | 3.85 |
| Wes Littleton | Cle | mr | 26 | .622 | 46 | .304 | 20 | .328 | 22 | .361 | 4.1 | 2.4 | 2.14 | 3.31 |
| Esteban Loaiza | Oak | mr | 37 | .220 | 23 | .087 | 3 | .107 | 4 | .143 | 0.4 | 0.4 | 0.36 | 0.40 |
| Boone Logan* | ChW | mr | 24 | 1.047 | 169 | .444 | 154 | .639 | 154 | .639 | 58.9 | 11.3 | 10.30 | 9.74 |
| Kyle Lohse | Bos | sp | 30 | .821 | 614 | .336 | 406 | .501 | 411 | .507 | 125.0 | 6.2 | 5.55 | 5.11 |
| Braden Looper | Tex | sp | 34 | .805 | 688 | .301 | 430 | .490 | 438 | .499 | 120.6 | 5.3 | 4.82 | 4.89 |
| Aquilino Lopez | Was | mr | 34 | .783 | 197 | .320 | 126 | .485 | 127 | .488 | 35.1 | 5.1 | 4.59 | 3.87 |
| Javier Lopez* | Tex | mr | 31 | .613 | 226 | .265 | 114 | .364 | 117 | .374 | 26.4 | 3.2 | 2.91 | 3.01 |
| Mark Lowe | Bos | mr | 26 | .949 | 69 | .348 | 56 | .589 | 56 | .589 | 18.5 | 9.1 | 8.48 | 8.42 |
| Ryan Madson | NYY | mr | 28 | .815 | 256 | .348 | 180 | .485 | 186 | .501 | 54.2 | 5.9 | 5.34 | 5.46 |
| Charlie Manning* | LAA | mr | 30 | .850 | 108 | .259 | 109 | .562 | 109 | .562 | 29.2 | 6.3 | 5.69 | 6.71 |
| Carlos Marmol | Bal | mr | 26 | .521 | 122 | .238 | 82 | .333 | 85 | .346 | 17.3 | 2.6 | 2.38 | 2.36 |
| Damaso Marte* | Cle | mr | 34 | .727 | 145 | .372 | 110 | .444 | 111 | .448 | 29.7 | 4.9 | 4.40 | 4.52 |
| Shairon Martis | KCR | sp | 22 | .794 | 87 | .264 | 91 | .538 | 91 | .538 | 22.8 | 5.2 | 4.73 | 4.74 |
| Tom Mastny | Tex | mr | 28 | .963 | 65 | .292 | 60 | .619 | 61 | .629 | 18.0 | 7.6 | 7.05 | 8.13 |
| Doug Mathis | Tor | sp | 26 | 1.077 | 24 | .333 | 22 | .710 | 22 | .710 | 7.9 | 11.3 | 10.72 | 9.41 |
| Daisuke Matsuzaka | NYY | sp | 28 | .600 | 531 | .254 | 322 | .378 | 329 | .387 | 70.8 | 3.2 | 2.85 | 2.95 |
| Kyle McClellan | Bal | mr | 25 | .705 | 223 | .287 | 138 | .426 | 141 | .435 | 37.4 | 4.5 | 4.19 | 4.31 |
| Dustin McGowan | Cle | sp | 27 | .792 | 382 | .361 | 258 | .466 | 265 | .478 | 80.6 | 5.9 | 5.34 | 5.11 |
| Gil Meche | KCR | sp | 30 | .673 | 613 | .292 | 401 | .423 | 403 | .425 | 97.6 | 3.9 | 3.55 | 3.43 |
| Andrew Miller* | LAA | sp | 24 | .794 | 352 | .366 | 236 | .468 | 241 | .478 | 71.8 | 5.9 | 5.26 | 4.88 |
| Jim Miller | Bos | mr | 27 | .250 | 5 | .200 | 1 | .125 | 1 | .125 | 0.1 | 0.5 | 0.43 | 0.40 |
| Trever Miller* | Tor | mr | 36 | .866 | 91 | .374 | 76 | .528 | 78 | .542 | 20.7 | 5.7 | 5.07 | 5.75 |
| Kevin Millwood | Mtl | sp | 34 | .782 | 649 | .328 | 397 | .463 | 405 | .472 | 119.4 | 5.6 | 4.99 | 5.03 |
| Zach Miner | Det | mr | 27 | .608 | 287 | .244 | 135 | .365 | 140 | .378 | 30.9 | 3.0 | 2.79 | 2.51 |
| Brian Moehler | Tex | sp | 37 | .830 | 645 | .304 | 415 | .510 | 417 | .513 | 120.6 | 5.8 | 5.23 | 4.93 |
| Brandon Morrow | Was | mr | 24 | .560 | 199 | .191 | 127 | .375 | 129 | .381 | 24.4 | 2.5 | 2.30 | 1.97 |
| Charlie Morton | Det | sp | 25 | .935 | 224 | .335 | 175 | .578 | 176 | .581 | 57.7 | 8.5 | 7.67 | 7.92 |
| Guillermo Mota |   | mr | 35 | .748 | 228 | .289 | 162 | .470 | 163 | .472 | 41.3 | 4.6 | 4.18 | 4.22 |
| Jason Motte | Was | mr | 27 | .651 | 38 | .316 | 20 | .377 | 20 | .377 | 5.0 | 3.5 | 3.19 | 3.49 |
| Edward Mujica | Min | mr | 25 | .846 | 86 | .360 | 55 | .495 | 56 | .505 | 16.0 | 5.6 | 5.20 | 5.36 |
| Mike Mussina | Bos | sp | 40 | .712 | 698 | .338 | 370 | .406 | 383 | .420 | 104.2 | 4.3 | 3.85 | 3.53 |
| Brett Myers | Oak | sp | 28 | .708 | 592 | .275 | 381 | .446 | 383 | .448 | 94.7 | 4.1 | 3.76 | 3.47 |
| Joe Nelson | Bos | mr | 34 | .563 | 192 | .292 | 114 | .348 | 115 | .351 | 25.1 | 2.8 | 2.48 | 2.27 |
| Jonathon Niese* | ChW | sp | 22 | 1.122 | 127 | .433 | 123 | .703 | 123 | .703 | 46.5 | 12.3 | 11.19 | 11.01 |
| Fernando Nieve | Bos | mr | 26 | 1.290 | 11 | .364 | 12 | .750 | 12 | .750 | 5.4 | 20.7 | 18.67 | 21.72 |
| Dustin Nippert | ChW | mr | 28 | .814 | 305 | .338 | 221 | .499 | 224 | .506 | 66.9 | 6.2 | 5.53 | 5.67 |
| Hideki Okajima* | Was | mr | 33 | .649 | 111 | .261 | 69 | .399 | 70 | .405 | 17.3 | 3.9 | 3.47 | 3.77 |
| Darren Oliver* | Oak | mr | 38 | .653 | 197 | .299 | 101 | .388 | 103 | .396 | 23.4 | 3.2 | 2.85 | 2.51 |
| Garrett Olson* | LAA | sp | 25 | .791 | 467 | .332 | 320 | .480 | 322 | .483 | 95.6 | 5.8 | 5.28 | 4.98 |
| Vicente Padilla | KCR | sp | 31 | .747 | 554 | .309 | 366 | .440 | 387 | .466 | 100.8 | 4.8 | 4.28 | 4.68 |
| Matt Palmer | Tor | sp | 30 | 1.017 | 23 | .391 | 16 | .552 | 17 | .586 | 6.6 | 11.1 | 12.27 | 13.85 |
| Jonathan Papelbon | Min | cl | 28 | .534 | 233 | .279 | 108 | .309 | 111 | .317 | 23.6 | 2.4 | 2.15 | 2.04 |
| Manny Parra* | NYY | sp | 26 | .889 | 475 | .349 | 397 | .551 | 401 | .556 | 124.5 | 7.3 | 6.63 | 6.93 |
| John Parrish* | Mtl | mr | 31 | .746 | 89 | .303 | 58 | .464 | 58 | .464 | 15.1 | 5.0 | 4.48 | 5.09 |
| Scott Patterson | Cle | mr | 30 | 1.333 | 11 | .636 | 11 | .733 | 11 | .733 | 5.9 | 31.6 | 28.45 | 33.64 |
| Carl Pavano | Cle | sp | 33 | .831 | 160 | .344 | 108 | .491 | 111 | .505 | 35.4 | 6.9 | 6.37 | 6.31 |
| Jake Peavy | Oak | sp | 28 | .700 | 558 | .315 | 358 | .424 | 363 | .430 | 94.9 | 4.3 | 3.88 | 3.91 |
| Tony Pena | Oak | mr | 27 | .693 | 259 | .320 | 143 | .407 | 145 | .413 | 37.2 | 4.0 | 3.66 | 3.40 |
| Joel Peralta | Tex | mr | 33 | .869 | 241 | .245 | 209 | .587 | 210 | .590 | 55.4 | 5.9 | 5.41 | 4.98 |
| Troy Percival | LAA | cl | 39 | .798 | 142 | .148 | 132 | .552 | 133 | .556 | 32.1 | 5.0 | 4.48 | 4.10 |
| Chris Perez | Mtl | mr | 23 | .717 | 94 | .330 | 68 | .439 | 69 | .445 | 16.9 | 4.4 | 3.95 | 4.54 |
| Odalis Perez* | Tor | sp | 32 | .887 | 520 | .356 | 379 | .533 | 388 | .546 | 119.0 | 6.9 | 6.29 | 6.32 |
| Oliver Perez* | LAA | sp | 27 | .813 | 288 | .365 | 203 | .480 | 206 | .487 | 63.3 | 6.4 | 5.72 | 5.92 |
| Glen Perkins* | Oak | sp | 26 | .790 | 639 | .305 | 399 | .480 | 405 | .487 | 111.4 | 5.2 | 4.74 | 4.73 |
| Scott Proctor | Mtl | mr | 32 | .758 | 90 | .289 | 75 | .481 | 77 | .494 | 19.5 | 4.9 | 4.40 | 4.67 |
| David Purcey* | ChW | sp | 27 | .814 | 274 | .332 | 209 | .501 | 210 | .504 | 62.2 | 6.0 | 5.40 | 5.35 |
| Horacio Ramirez* |   | mr | 29 | .735 | 177 | .305 | 90 | .409 | 97 | .441 | 28.1 | 5.1 | 4.64 | 4.14 |
| Ramon Ramirez | Oak | mr | 27 | .511 | 222 | .252 | 105 | .308 | 107 | .314 | 21.4 | 2.2 | 1.97 | 1.71 |
| Ramon Ramirez | Det | sp | 26 | .496 | 34 | .147 | 20 | .345 | 20 | .345 | 3.4 | 2.1 | 1.86 | 1.85 |
| Tim Redding | Was | sp | 31 | .791 | 680 | .301 | 473 | .492 | 477 | .496 | 134.2 | 5.6 | 4.97 | 5.07 |
| Mark Redman* | Sea | sp | 35 | .966 | 236 | .318 | 186 | .612 | 187 | .615 | 58.6 | 8.0 | 7.46 | 7.40 |
| Chris Resop | Cle | mr | 26 | .930 | 45 | .333 | 40 | .606 | 40 | .606 | 12.9 | 8.3 | 7.48 | 6.64 |
| Anthony Reyes | Cle | sp | 27 | .825 | 207 | .338 | 136 | .495 | 138 | .502 | 40.2 | 5.9 | 5.22 | 5.37 |
| Clayton Richard* | Tex | sp | 25 | .771 | 326 | .313 | 201 | .466 | 203 | .471 | 59.0 | 5.4 | 4.93 | 4.40 |
| Scott Richmond | Min | sp | 29 | .815 | 124 | .331 | 77 | .470 | 83 | .506 | 23.8 | 5.7 | 5.12 | 4.41 |
| Juan Rincon | Sea | mr | 30 | .878 | 297 | .347 | 230 | .528 | 236 | .541 | 74.1 | 7.2 | 6.74 | 7.01 |
| Francisco Rodriguez | Tor | cl | 27 | .644 | 236 | .271 | 151 | .405 | 154 | .413 | 34.8 | 3.5 | 3.24 | 3.19 |
| Kenny Rogers* | Tex | sp | 44 | .854 | 583 | .317 | 402 | .523 | 408 | .531 | 117.3 | 6.1 | 5.55 | 5.67 |
| J.C. Romero* | Det | mr | 33 | .643 | 204 | .221 | 149 | .420 | 154 | .434 | 32.7 | 3.6 | 3.24 | 3.36 |
| Sergio Romo | Min | mr | 26 | .558 | 105 | .181 | 57 | .348 | 61 | .372 | 12.2 | 2.7 | 2.39 | 2.15 |
| Carlos Rosa | KCR | mr | 24 | .937 | 27 | .333 | 22 | .579 | 22 | .579 | 6.9 | 7.8 | 7.33 | 6.53 |
| Leo Rosales | Tor | mr | 28 | 1.417 | 6 | .667 | 6 | .750 | 6 | .750 | 3.4 | 45.8 | 82.38 | 112.59 |
| Josh Rupe | ChW | mr | 26 | .788 | 292 | .271 | 198 | .474 | 209 | .500 | 53.0 | 5.0 | 4.57 | 5.16 |
| B.J. Ryan* |   | cl | 33 | .591 | 211 | .256 | 120 | .365 | 122 | .371 | 25.9 | 2.9 | 2.62 | 2.62 |
| C.C. Sabathia* | Oak | sp | 28 | .725 | 679 | .327 | 446 | .437 | 456 | .447 | 121.1 | 4.5 | 4.07 | 3.86 |
| Jeff Samardzija | ChW | mr | 24 | .768 | 115 | .313 | 76 | .437 | 82 | .471 | 23.5 | 5.8 | 5.29 | 6.15 |
| Chris Sampson | NYY | mr | 31 | .716 | 446 | .278 | 231 | .429 | 235 | .437 | 58.7 | 4.0 | 3.67 | 3.32 |
| Duaner Sanchez | Bos | mr | 29 | .729 | 170 | .276 | 103 | .440 | 105 | .449 | 28.5 | 4.8 | 4.44 | 4.34 |
| Johan Santana* | Sea | sp | 30 | .681 | 617 | .280 | 380 | .419 | 388 | .427 | 93.2 | 3.9 | 3.49 | 3.52 |
| Joe Saunders* | LAA | sp | 28 | .653 | 681 | .267 | 340 | .390 | 346 | .397 | 80.7 | 3.3 | 3.04 | 3.04 |
| Max Scherzer | Tor | mr | 24 | .664 | 191 | .309 | 126 | .396 | 132 | .415 | 29.6 | 3.6 | 3.27 | 4.07 |
| Scott Schoeneweis* | Det | mr | 35 | .870 | 224 | .335 | 165 | .524 | 167 | .530 | 49.1 | 6.4 | 5.77 | 6.11 |
| Bobby Seay* | Bal | mr | 31 | .739 | 182 | .390 | 123 | .433 | 123 | .433 | 34.4 | 4.8 | 4.31 | 4.70 |
| Ben Sheets | Oak | sp | 30 | .738 | 627 | .314 | 404 | .455 | 405 | .456 | 111.3 | 4.8 | 4.40 | 3.85 |
| George Sherrill* | KCR | cl | 32 | .724 | 182 | .291 | 144 | .459 | 145 | .462 | 37.6 | 4.7 | 4.23 | 3.76 |
| Scot Shields | Min | mr | 33 | .656 | 249 | .281 | 153 | .402 | 156 | .409 | 33.3 | 3.1 | 2.84 | 2.97 |
| Kevin Slowey | Tor | sp | 25 | .707 | 659 | .287 | 382 | .439 | 383 | .440 | 97.9 | 4.2 | 3.83 | 3.27 |
| Greg Smith* | Det | sp | 25 | .710 | 565 | .225 | 355 | .459 | 357 | .461 | 85.1 | 4.1 | 3.73 | 3.66 |
| Joe Smith | Tor | mr | 25 | .715 | 251 | .279 | 168 | .447 | 172 | .457 | 41.0 | 4.3 | 3.89 | 3.93 |
| John Smoltz | Mtl | sp | 42 | .751 | 156 | .346 | 115 | .469 | 115 | .469 | 32.9 | 5.2 | 4.68 | 3.85 |
| Ian Snell | Tex | sp | 27 | 1.048 | 88 | .409 | 75 | .636 | 76 | .644 | 27.6 | 10.5 | 9.30 | 8.78 |
| Rafael Soriano | Min | mr | 29 | .877 | 22 | .409 | 33 | .569 | 33 | .569 | 9.5 | 8.3 | 7.47 | 8.70 |
| Jeremy Sowers* | Det | sp | 26 | .681 | 378 | .272 | 206 | .418 | 208 | .422 | 49.4 | 3.7 | 3.32 | 3.29 |
| Justin Speier | NYY | mr | 35 | .697 | 195 | .226 | 127 | .441 | 130 | .451 | 32.2 | 4.2 | 3.73 | 3.21 |
| Russ Springer | Min | mr | 40 | .775 | 199 | .307 | 155 | .486 | 156 | .489 | 45.0 | 5.7 | 5.07 | 4.82 |
| Mitch Stetter* | Was | mr | 28 | .755 | 67 | .358 | 60 | .458 | 63 | .481 | 17.7 | 5.9 | 5.37 | 5.20 |
| Brian Stokes | Was | mr | 29 | .732 | 107 | .411 | 56 | .397 | 57 | .404 | 16.3 | 4.5 | 4.01 | 4.52 |
| Huston Street | NYY | cl | 25 | .650 | 209 | .278 | 133 | .403 | 135 | .409 | 31.6 | 3.6 | 3.32 | 3.26 |
| Jeff Suppan | Bal | sp | 34 | .880 | 656 | .340 | 450 | .527 | 458 | .536 | 138.6 | 6.6 | 6.04 | 6.49 |
| Jack Taschner* | NYY | mr | 31 | .993 | 19 | .368 | 18 | .643 | 18 | .643 | 6.2 | 9.8 | 8.37 | 7.14 |
| Brad Thompson | KCR | mr | 27 | .940 | 274 | .339 | 202 | .572 | 205 | .581 | 65.7 | 7.8 | 7.03 | 6.98 |
| Rich Thompson | Mtl | mr | 24 | .619 | 12 | .333 | 5 | .333 | 5 | .333 | 1.1 | 2.8 | 2.51 | 3.55 |
| Ramon Troncoso | Tex | mr | 26 | .772 | 25 | .400 | 19 | .475 | 19 | .475 | 5.0 | 4.6 | 4.02 | 4.08 |
| Justin Verlander | Cle | sp | 26 | .691 | 609 | .299 | 372 | .415 | 381 | .425 | 97.9 | 4.2 | 3.82 | 3.85 |
| Edinson Volquez | Mtl | sp | 25 | .715 | 494 | .312 | 349 | .431 | 364 | .450 | 95.7 | 4.8 | 4.35 | 4.59 |
| Chris Volstad | KCR | sp | 22 | .697 | 380 | .292 | 201 | .404 | 207 | .416 | 50.0 | 3.8 | 3.40 | 3.88 |
| Doug Waechter | ChW | mr | 28 | .842 | 163 | .350 | 115 | .509 | 117 | .518 | 35.9 | 6.4 | 5.77 | 5.43 |
| Tim Wakefield | Min | sp | 42 | .642 | 645 | .234 | 345 | .390 | 361 | .408 | 82.8 | 3.4 | 3.13 | 3.04 |
| Jamie Walker* | Bal | mr | 37 | .955 | 147 | .293 | 129 | .611 | 131 | .621 | 38.7 | 7.3 | 6.49 | 6.60 |
| Tyler Walker | Sea | mr | 33 | .742 | 271 | .266 | 208 | .473 | 214 | .486 | 53.9 | 4.7 | 4.27 | 4.09 |
| Jarrod Washburn* | Det | sp | 34 | .898 | 446 | .316 | 325 | .545 | 335 | .562 | 101.2 | 7.0 | 6.30 | 6.48 |
| Chris Waters* | Tor | sp | 28 | .659 | 94 | .287 | 50 | .388 | 52 | .403 | 13.5 | 4.1 | 3.64 | 3.06 |
| David Weathers | Det | mr | 39 | .657 | 205 | .288 | 107 | .386 | 110 | .397 | 25.7 | 3.4 | 3.06 | 3.03 |
| Brandon Webb | Det | sp | 30 | .712 | 514 | .315 | 308 | .422 | 317 | .434 | 82.4 | 4.3 | 3.89 | 3.90 |
| Kip Wells | Tex | mr | 32 | .879 | 14 | .214 | 12 | .600 | 12 | .600 | 3.4 | 7.1 | 6.93 | 6.21 |
| Dontrelle Willis* | Was | sp | 27 | .714 | 138 | .188 | 113 | .496 | 113 | .496 | 26.3 | 4.7 | 4.18 | 4.16 |
| C.J. Wilson* | KCR | cl | 28 | .734 | 212 | .283 | 149 | .463 | 150 | .466 | 37.0 | 4.5 | 4.03 | 4.23 |
| Randy Wolf* | ChW | sp | 32 | .792 | 635 | .321 | 428 | .475 | 439 | .487 | 117.7 | 5.1 | 4.59 | 5.05 |
| Brian Wolfe | Mtl | mr | 28 | .874 | 89 | .337 | 74 | .548 | 74 | .548 | 22.8 | 7.1 | 6.45 | 6.88 |
| Kerry Wood | Det | cl | 32 | .773 | 204 | .387 | 151 | .456 | 156 | .471 | 44.7 | 5.6 | 5.03 | 4.44 |
| Michael Wuertz | Tex | mr | 30 | .855 | 153 | .353 | 116 | .525 | 116 | .525 | 37.6 | 7.2 | 6.48 | 6.54 |
| Yasuhiko Yabuta | Cle | mr | 36 | .533 | 15 | .267 | 4 | .267 | 4 | .267 | 0.3 | 0.5 | 0.46 | 1.74 |
| Charlie Zink | Cle | sp | 29 | .705 | 37 | .324 | 20 | .417 | 20 | .417 | 5.5 | 4.5 | 4.17 | 3.84 |
| Barry Zito* | ChW | sp | 31 | .833 | 559 | .301 | 438 | .516 | 445 | .524 | 129.5 | 6.5 | 5.88 | 6.43 |
| Joel Zumaya | KCR | mr | 24 | .593 | 130 | .223 | 81 | .389 | 81 | .389 | 18.0 | 3.3 | 2.95 | 2.91 |
| Start |
| Name | Team | P | Age | GS | CG | CG% | SHO | QS | QS% | RS | RS/G | RL | RLS | RL% | NP/G | STR% |
| Alfredo Aceves | Was | sp | 26 | 3 | 0 | .000 | 0 | 0 | .000 | 12 | 4.0 | 2 | 0 | .000 | 102.0 | .575 |
| Nick Adenhart | Bal | sp | 22 | 3 | 0 | .000 | 0 | 1 | .333 | 19 | 6.3 | 1 | 1 | 1.000 | 80.7 | .595 |
| Jeremy Affeldt* | Bos | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 2 | .154 | 19.8 | .621 |
| Jonathan Albaladejo | Min | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 8.0 | .625 |
| Matt Albers | Tex | mr | 26 | 7 | 0 | .000 | 0 | 1 | .143 | 31 | 4.4 | 16 | 5 | .313 | 47.8 | .579 |
| Jose Arredondo | Cle | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 | 19.1 | .623 |
| Luis Ayala | Bal | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 13 | .433 | 19.9 | .611 |
| Brandon Backe | Bal | sp | 31 | 30 | 1 | .033 | 0 | 9 | .300 | 120 | 4.0 | 33 | 15 | .455 | 95.7 | .591 |
| Burke Badenhop | KCR | sp | 26 | 10 | 0 | .000 | 0 | 5 | .500 | 71 | 7.1 | 10 | 4 | .400 | 85.3 | .593 |
| Cha Seung Baek | NYY | sp | 29 | 25 | 0 | .000 | 0 | 6 | .240 | 92 | 3.7 | 29 | 9 | .310 | 89.8 | .610 |
| Homer Bailey | Tor | sp | 23 | 5 | 0 | .000 | 0 | 2 | .400 | 33 | 6.6 | 6 | 2 | .333 | 70.4 | .597 |
| Josh Banks | Mtl | sp | 26 | 14 | 0 | .000 | 0 | 6 | .429 | 64 | 4.6 | 16 | 3 | .188 | 67.1 | .589 |
| Brian Bass | Bal | mr | 27 | 2 | 0 | .000 | 0 | 2 | 1.000 | 8 | 4.0 | 9 | 0 | .000 | 44.8 | .641 |
| Miguel Batista | Bal | mr | 38 | 14 | 1 | .071 | 0 | 4 | .286 | 60 | 4.3 | 32 | 11 | .344 | 52.5 | .567 |
| Denny Bautista | Sea | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 23.6 | .547 |
| T.J. Beam | LAA | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 | 38.4 | .599 |
| Josh Beckett | KCR | sp | 29 | 30 | 5 | .167 | 1 | 18 | .600 | 133 | 4.4 | 18 | 10 | .556 | 108.2 | .654 |
| Joe Beimel* | Min | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 8 | .296 | 22.5 | .598 |
| Matt Belisle | Tex | sp | 29 | 3 | 0 | .000 | 0 | 1 | .333 | 8 | 2.7 | 3 | 1 | .333 | 67.0 | .667 |
| Joaquin Benoit | Oak | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 9.5 | .509 |
| Jason Bergmann | KCR | sp | 27 | 25 | 0 | .000 | 0 | 10 | .400 | 131 | 5.2 | 18 | 7 | .389 | 87.8 | .636 |
| Randor Bierd | Mtl | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 3 | .500 | 28.5 | .592 |
| Jerry Blevins* | Mtl | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 3 | .214 | 19.0 | .624 |
| Mitchell Boggs | Det | sp | 25 | 4 | 0 | .000 | 0 | 0 | .000 | 23 | 5.8 | 3 | 0 | .000 | 86.3 | .548 |
| Jeremy Bonderman | Was | sp | 26 | 9 | 1 | .111 | 0 | 8 | .889 | 50 | 5.6 | 9 | 2 | .222 | 102.4 | .612 |
| Eddie Bonine | Tex | sp | 28 | 4 | 0 | .000 | 0 | 4 | 1.000 | 13 | 3.3 | 1 | 0 | .000 | 101.3 | .672 |
| Michael Bowden | NYY | sp | 22 | 5 | 0 | .000 | 0 | 1 | .200 | 18 | 3.6 | 4 | 1 | .250 | 90.6 | .611 |
| Dallas Braden* | Mtl | sp | 25 | 13 | 1 | .077 | 0 | 8 | .615 | 82 | 6.3 | 13 | 3 | .231 | 71.4 | .635 |
| Chad Bradford | Det | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 10 | .385 | 22.1 | .677 |
| Craig Breslow* | NYY | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 4 | .308 | 21.3 | .600 |
| Doug Brocail | Tor | mr | 42 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 9 | .333 | 26.0 | .623 |
| Andrew Brown | Mtl | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 3 | .250 | 23.6 | .596 |
| Brian Bruney |   | mr | 27 | 5 | 0 | .000 | 0 | 5 | 1.000 | 21 | 4.2 | 7 | 1 | .143 | 38.5 | .589 |
| Clay Buchholz | Cle | sp | 24 | 20 | 0 | .000 | 0 | 6 | .300 | 116 | 5.8 | 24 | 12 | .500 | 90.8 | .594 |
| Taylor Buchholz | ChW | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 25.9 | .630 |
| Bryan Bullington | Bos | sp | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 31.0 | .645 |
| Brian Burres* | Tex | sp | 28 | 30 | 0 | .000 | 0 | 7 | .233 | 111 | 3.7 | 35 | 18 | .514 | 88.7 | .616 |
| Paul Byrd | Tor | sp | 38 | 30 | 4 | .133 | 0 | 16 | .533 | 140 | 4.7 | 23 | 7 | .304 | 89.6 | .657 |
| Daniel Cabrera | Bal | sp | 28 | 30 | 0 | .000 | 0 | 12 | .400 | 148 | 4.9 | 27 | 16 | .593 | 104.6 | .573 |
| Matt Cain | NYY | sp | 24 | 34 | 1 | .029 | 0 | 12 | .353 | 137 | 4.0 | 29 | 7 | .241 | 100.2 | .602 |
| Shawn Camp | Oak | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 5 | .263 | 20.0 | .650 |
| Jorge Campillo | Bos | sp | 30 | 30 | 0 | .000 | 0 | 13 | .433 | 173 | 5.8 | 22 | 5 | .227 | 80.9 | .628 |
| Matt Capps | Sea | cl | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 | 19.2 | .667 |
| Vinnie Chulk | Was | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 23.6 | .661 |
| Tyler Clippard | Sea | sp | 24 | 2 | 0 | .000 | 0 | 0 | .000 | 3 | 1.5 | 1 | 0 | .000 | 78.5 | .522 |
| Todd Coffey | Cle | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 19.2 | .563 |
| Phil Coke* | Bal | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 17.4 | .712 |
| Bartolo Colon | Sea | sp | 36 | 11 | 3 | .273 | 1 | 2 | .182 | 55 | 5.0 | 9 | 2 | .222 | 99.5 | .668 |
| Francisco Cordero | Tex | cl | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 0 | .000 | 20.9 | .586 |
| Lance Cormier | Oak | mr | 28 | 5 | 1 | .200 | 0 | 3 | .600 | 28 | 5.6 | 20 | 9 | .450 | 40.1 | .608 |
| Manuel Corpas | NYY | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 2 | .091 | 21.3 | .637 |
| Kevin Correia | Sea | sp | 28 | 19 | 1 | .053 | 1 | 5 | .263 | 66 | 3.5 | 26 | 13 | .500 | 77.8 | .603 |
| Juan Cruz | Cle | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 11 | .367 | 24.4 | .553 |
| Johnny Cueto | Sea | sp | 23 | 32 | 0 | .000 | 0 | 14 | .438 | 128 | 4.0 | 28 | 10 | .357 | 99.7 | .597 |
| Eulogio De La Cruz | ChW | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 6 | 1.000 | 44.8 | .504 |
| Jorge De La Rosa* | Was | sp | 28 | 26 | 0 | .000 | 0 | 14 | .538 | 117 | 4.5 | 35 | 10 | .286 | 91.4 | .581 |
| Manny Delcarmen | Cle | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 14.5 | .624 |
| Ryan Dempster | LAA | sp | 32 | 33 | 2 | .061 | 1 | 20 | .606 | 157 | 4.8 | 20 | 8 | .400 | 103.8 | .614 |
| Joey Devine | Bos | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 4 | .500 | 32.0 | .616 |
| R.A. Dickey | Min | mr | 34 | 18 | 0 | .000 | 0 | 9 | .500 | 118 | 6.6 | 23 | 6 | .261 | 94.9 | .603 |
| Mark DiFelice | Bos | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 8 | .533 | 16.6 | .628 |
| Tim Dillard | Min | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 25.0 | .520 |
| Octavio Dotel | Mtl | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 | 19.4 | .631 |
| Scott Downs* | LAA | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 8 | .500 | 21.7 | .634 |
| Justin Duchscherer | Cle | sp | 31 | 25 | 5 | .200 | 4 | 18 | .720 | 144 | 5.8 | 7 | 3 | .429 | 91.9 | .662 |
| Zach Duke* | Tor | sp | 26 | 15 | 1 | .067 | 0 | 6 | .400 | 58 | 3.9 | 18 | 7 | .389 | 82.9 | .610 |
| Chad Durbin | KCR | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 4 | .200 | 22.3 | .594 |
| Adam Eaton | Bal | sp | 31 | 22 | 1 | .045 | 0 | 7 | .318 | 94 | 4.3 | 23 | 6 | .261 | 96.9 | .605 |
| Scott Elarton | LAA | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 15.5 | .742 |
| Alan Embree* | Sea | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 35 | 14 | .400 | 25.8 | .591 |
| Shawn Estes* | Sea | sp | 36 | 12 | 0 | .000 | 0 | 4 | .333 | 68 | 5.7 | 17 | 8 | .471 | 89.8 | .578 |
| Dana Eveland* | LAA | sp | 25 | 30 | 0 | .000 | 0 | 19 | .633 | 157 | 5.2 | 33 | 8 | .242 | 96.8 | .592 |
| Scott Eyre* | LAA | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 1 | .091 | 19.3 | .667 |
| Kyle Farnsworth | Mtl | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 5 | .455 | 23.9 | .639 |
| Ryan Feierabend* | ChW | sp | 23 | 20 | 0 | .000 | 0 | 2 | .100 | 92 | 4.6 | 22 | 1 | .045 | 80.4 | .603 |
| Pedro Feliciano* | NYY | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 14 | .500 | 21.1 | .611 |
| Nelson Figueroa | KCR | mr | 35 | 3 | 0 | .000 | 0 | 0 | .000 | 19 | 6.3 | 10 | 4 | .400 | 41.8 | .556 |
| Keith Foulke | Was | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 | 19.8 | .544 |
| Jeff Francis* | ChW | sp | 28 | 28 | 1 | .036 | 0 | 12 | .429 | 135 | 4.8 | 28 | 8 | .286 | 102.0 | .626 |
| Ryan Franklin | Det | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 7 | .333 | 21.2 | .602 |
| Eric Gagne | Tor | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 3 | .300 | 22.7 | .582 |
| Freddy Garcia | Min | sp | 33 | 6 | 1 | .167 | 0 | 2 | .333 | 31 | 5.2 | 6 | 1 | .167 | 97.3 | .598 |
| Jaime Garcia* | Sea | mr | 22 | 1 | 0 | .000 | 0 | 0 | .000 | 5 | 5.0 | 7 | 2 | .286 | 36.8 | .558 |
| Jon Garland | Mtl | sp | 29 | 32 | 0 | .000 | 0 | 10 | .313 | 160 | 5.0 | 32 | 7 | .219 | 88.1 | .623 |
| Matt Garza | Bal | sp | 25 | 30 | 2 | .067 | 0 | 17 | .567 | 135 | 4.5 | 26 | 12 | .462 | 99.7 | .628 |
| Geoff Geary | LAA | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 7 | .412 | 22.7 | .610 |
| Josh Geer | ChW | sp | 26 | 9 | 0 | .000 | 0 | 5 | .556 | 46 | 5.1 | 5 | 2 | .400 | 92.7 | .641 |
| Franklyn German | Min | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 0 | .000 | 26.1 | .546 |
| Justin Germano | Tex | sp | 26 | 2 | 0 | .000 | 0 | 1 | .500 | 5 | 2.5 | 4 | 2 | .500 | 54.2 | .646 |
| Matt Ginter | Min | sp | 31 | 2 | 0 | .000 | 0 | 2 | 1.000 | 7 | 3.5 | 1 | 0 | .000 | 98.0 | .719 |
| Gary Glover | Tor | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 1 | .053 | 33.3 | .638 |
| Jimmy Gobble* | Tor | mr | 27 | 1 | 0 | .000 | 0 | 0 | .000 | 3 | 3.0 | 5 | 3 | .600 | 15.6 | .545 |
| Edgar Gonzalez | LAA | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 31.0 | .613 |
| Gio Gonzalez* | Sea | sp | 23 | 11 | 0 | .000 | 0 | 1 | .091 | 48 | 4.4 | 18 | 4 | .222 | 90.8 | .541 |
| Mike Gonzalez* | Cle | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 15.2 | .690 |
| Tom Gorzelanny* | Sea | sp | 26 | 25 | 0 | .000 | 0 | 7 | .280 | 90 | 3.6 | 24 | 6 | .250 | 91.8 | .547 |
| Sean Green | ChW | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 9 | .300 | 22.5 | .601 |
| Zack Greinke | Bos | sp | 25 | 32 | 2 | .063 | 1 | 19 | .594 | 174 | 5.4 | 21 | 9 | .429 | 103.7 | .650 |
| Matt Guerrier | Cle | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 37 | 9 | .243 | 18.6 | .603 |
| Charlie Haeger | Cle | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 36.0 | .528 |
| Jason Hammel | ChW | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 6 | .400 | 29.0 | .609 |
| Mike Hampton* | Cle | sp | 36 | 15 | 0 | .000 | 0 | 4 | .267 | 81 | 5.4 | 17 | 8 | .471 | 88.1 | .633 |
| Joel Hanrahan | Tex | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 3 | .120 | 30.0 | .615 |
| J.A. Happ* | LAA | sp | 26 | 5 | 0 | .000 | 0 | 1 | .200 | 33 | 6.6 | 6 | 2 | .333 | 90.2 | .557 |
| Aaron Harang | Tor | sp | 31 | 30 | 3 | .100 | 2 | 12 | .400 | 151 | 5.0 | 19 | 7 | .368 | 97.9 | .639 |
| Aaron Heilman | Tor | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 34 | 12 | .353 | 24.6 | .538 |
| Mark Hendrickson* | Was | sp | 35 | 22 | 1 | .045 | 0 | 12 | .545 | 116 | 5.3 | 11 | 3 | .273 | 84.7 | .627 |
| Clay Hensley | Was | mr | 29 | 4 | 0 | .000 | 0 | 2 | .500 | 26 | 6.5 | 18 | 8 | .444 | 39.1 | .566 |
| Felix Hernandez | Min | sp | 23 | 32 | 3 | .094 | 2 | 17 | .531 | 141 | 4.4 | 32 | 14 | .438 | 108.2 | .593 |
| Alex Hinshaw* | NYY | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 | 22.6 | .573 |
| Luke Hochevar | NYY | sp | 25 | 26 | 1 | .038 | 0 | 11 | .423 | 99 | 3.8 | 23 | 12 | .522 | 94.6 | .610 |
| J.P. Howell* | Bos | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 3 | .214 | 22.0 | .582 |
| Tim Hudson | Det | sp | 33 | 14 | 1 | .071 | 1 | 11 | .786 | 59 | 4.2 | 6 | 3 | .500 | 98.3 | .617 |
| Jason Isringhausen | Oak | cl | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 11.8 | .511 |
| Edwin Jackson | Min | sp | 25 | 31 | 1 | .032 | 0 | 12 | .387 | 150 | 4.8 | 34 | 11 | .324 | 90.5 | .603 |
| Zach Jackson* | ChW | sp | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 5 | .500 | 37.9 | .634 |
| Chuck James* | Sea | sp | 27 | 5 | 0 | .000 | 0 | 0 | .000 | 21 | 4.2 | 6 | 1 | .167 | 96.0 | .590 |
| Bobby Jenks | KCR | cl | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 15.0 | .660 |
| Jason Johnson | Was | mr | 35 | 4 | 0 | .000 | 0 | 2 | .500 | 23 | 5.8 | 5 | 0 | .000 | 92.8 | .617 |
| Josh Johnson | Min | sp | 25 | 19 | 2 | .105 | 0 | 10 | .526 | 69 | 3.6 | 20 | 7 | .350 | 100.7 | .614 |
| Todd Jones | Mtl | cl | 41 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 22.1 | .623 |
| Jorge Julio | Oak | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 4 | .400 | 26.0 | .587 |
| Jair Jurrjens | Mtl | sp | 23 | 31 | 2 | .065 | 1 | 17 | .548 | 123 | 4.0 | 28 | 2 | .071 | 99.6 | .623 |
| Scott Kazmir* | Bos | sp | 25 | 30 | 1 | .033 | 1 | 16 | .533 | 160 | 5.3 | 23 | 13 | .565 | 99.6 | .605 |
| Kyle Kendrick | Det | sp | 24 | 23 | 1 | .043 | 0 | 12 | .522 | 106 | 4.6 | 20 | 7 | .350 | 91.5 | .597 |
| Logan Kensing | Was | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 9 | .310 | 26.5 | .559 |
| Masa Kobayashi | Bal | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 9 | .474 | 19.7 | .676 |
| Eddie Kunz | ChW | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 20.8 | .536 |
| Hong-Chih Kuo* | Bos | mr | 27 | 3 | 0 | .000 | 0 | 2 | .667 | 10 | 3.3 | 12 | 5 | .417 | 38.5 | .647 |
| John Lackey | Cle | sp | 30 | 28 | 3 | .107 | 2 | 14 | .500 | 133 | 4.8 | 9 | 3 | .333 | 98.4 | .647 |
| John Lannan* | Was | sp | 24 | 31 | 0 | .000 | 0 | 14 | .452 | 129 | 4.2 | 30 | 7 | .233 | 96.9 | .574 |
| Brandon League | Min | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 3 | .600 | 25.8 | .610 |
| Wil Ledezma* | Was | mr | 28 | 8 | 0 | .000 | 0 | 1 | .125 | 36 | 4.5 | 12 | 5 | .417 | 63.7 | .529 |
| Jensen Lewis | Cle | cl | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 7 | .233 | 25.0 | .614 |
| Brad Lidge | ChW | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 4 | .800 | 31.4 | .567 |
| Mike Lincoln | Sea | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 10 | .400 | 28.1 | .620 |
| Scott Linebrink | LAA | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 7 | .538 | 19.2 | .658 |
| Francisco Liriano* | Min | sp | 25 | 18 | 0 | .000 | 0 | 10 | .556 | 69 | 3.8 | 17 | 6 | .353 | 101.3 | .605 |
| Wes Littleton | Cle | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 17.2 | .594 |
| Esteban Loaiza | Oak | mr | 37 | 1 | 0 | .000 | 0 | 1 | 1.000 | 2 | 2.0 | 0 | 0 | .000 | 85.0 | .682 |
| Boone Logan* | ChW | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 5 | .294 | 21.1 | .633 |
| Kyle Lohse | Bos | sp | 30 | 33 | 0 | .000 | 0 | 12 | .364 | 191 | 5.8 | 42 | 16 | .381 | 87.6 | .636 |
| Braden Looper | Tex | sp | 34 | 33 | 3 | .091 | 1 | 15 | .455 | 142 | 4.3 | 22 | 5 | .227 | 88.6 | .636 |
| Aquilino Lopez | Was | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 | 25.5 | .676 |
| Javier Lopez* | Tex | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 7 | .259 | 22.8 | .611 |
| Mark Lowe | Bos | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 | 21.6 | .542 |
| Ryan Madson | NYY | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 37 | 10 | .270 | 22.5 | .628 |
| Charlie Manning* | LAA | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 7 | .583 | 22.8 | .530 |
| Carlos Marmol | Bal | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 | 21.5 | .576 |
| Damaso Marte* | Cle | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 38 | 4 | .105 | 16.6 | .592 |
| Shairon Martis | KCR | sp | 22 | 7 | 0 | .000 | 0 | 2 | .286 | 39 | 5.6 | 6 | 3 | .500 | 76.1 | .601 |
| Tom Mastny | Tex | mr | 28 | 4 | 0 | .000 | 0 | 0 | .000 | 29 | 7.3 | 4 | 0 | .000 | 93.8 | .605 |
| Doug Mathis | Tor | sp | 26 | 2 | 0 | .000 | 0 | 0 | .000 | 12 | 6.0 | 3 | 0 | .000 | 47.5 | .600 |
| Daisuke Matsuzaka | NYY | sp | 28 | 30 | 4 | .133 | 2 | 19 | .633 | 127 | 4.2 | 22 | 10 | .455 | 112.1 | .573 |
| Kyle McClellan | Bal | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 7 | .280 | 24.5 | .609 |
| Dustin McGowan | Cle | sp | 27 | 21 | 0 | .000 | 0 | 10 | .476 | 100 | 4.8 | 19 | 2 | .105 | 96.0 | .635 |
| Gil Meche | KCR | sp | 30 | 34 | 4 | .118 | 2 | 23 | .676 | 150 | 4.4 | 23 | 6 | .261 | 106.6 | .624 |
| Andrew Miller* | LAA | sp | 24 | 19 | 0 | .000 | 0 | 10 | .526 | 106 | 5.6 | 14 | 3 | .214 | 74.2 | .594 |
| Jim Miller | Bos | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 15.0 | .667 |
| Trever Miller* | Tor | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 6 | .462 | 21.3 | .571 |
| Kevin Millwood | Mtl | sp | 34 | 30 | 1 | .033 | 0 | 16 | .533 | 132 | 4.4 | 18 | 8 | .444 | 102.7 | .655 |
| Zach Miner | Det | mr | 27 | 5 | 0 | .000 | 0 | 4 | .800 | 29 | 5.8 | 13 | 8 | .615 | 38.0 | .626 |
| Brian Moehler | Tex | sp | 37 | 30 | 1 | .033 | 0 | 10 | .333 | 115 | 3.8 | 22 | 14 | .636 | 93.2 | .639 |
| Brandon Morrow | Was | mr | 24 | 3 | 0 | .000 | 0 | 3 | 1.000 | 9 | 3.0 | 15 | 3 | .200 | 33.7 | .600 |
| Charlie Morton | Det | sp | 25 | 14 | 0 | .000 | 0 | 3 | .214 | 43 | 3.1 | 18 | 8 | .444 | 82.2 | .564 |
| Guillermo Mota |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 37 | 9 | .243 | 26.2 | .582 |
| Jason Motte | Was | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 | 24.1 | .617 |
| Edward Mujica | Min | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 | 25.5 | .658 |
| Mike Mussina | Bos | sp | 40 | 34 | 2 | .059 | 0 | 18 | .529 | 156 | 4.6 | 28 | 9 | .321 | 92.2 | .681 |
| Brett Myers | Oak | sp | 28 | 30 | 2 | .067 | 1 | 17 | .567 | 161 | 5.4 | 22 | 10 | .455 | 104.7 | .625 |
| Joe Nelson | Bos | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 3 | .300 | 24.0 | .600 |
| Jonathon Niese* | ChW | sp | 22 | 7 | 0 | .000 | 0 | 0 | .000 | 36 | 5.1 | 7 | 3 | .429 | 94.0 | .603 |
| Fernando Nieve | Bos | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 25.5 | .510 |
| Dustin Nippert | ChW | mr | 28 | 17 | 0 | .000 | 0 | 5 | .294 | 84 | 4.9 | 14 | 4 | .286 | 96.2 | .617 |
| Hideki Okajima* | Was | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 2 | .100 | 22.0 | .592 |
| Darren Oliver* | Oak | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 1 | .083 | 16.6 | .668 |
| Garrett Olson* | LAA | sp | 25 | 27 | 0 | .000 | 0 | 12 | .444 | 133 | 4.9 | 26 | 8 | .308 | 92.5 | .597 |
| Vicente Padilla | KCR | sp | 31 | 31 | 1 | .032 | 1 | 13 | .419 | 146 | 4.7 | 26 | 16 | .615 | 99.0 | .612 |
| Matt Palmer | Tor | sp | 30 | 2 | 0 | .000 | 0 | 0 | .000 | 1 | 0.5 | 4 | 0 | .000 | 50.5 | .535 |
| Jonathan Papelbon | Min | cl | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 19.5 | .696 |
| Manny Parra* | NYY | sp | 26 | 30 | 1 | .033 | 0 | 9 | .300 | 132 | 4.4 | 31 | 12 | .387 | 89.8 | .592 |
| John Parrish* | Mtl | mr | 31 | 2 | 0 | .000 | 0 | 1 | .500 | 8 | 4.0 | 13 | 5 | .385 | 28.3 | .549 |
| Scott Patterson | Cle | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 5 | .625 | 12.0 | .521 |
| Carl Pavano | Cle | sp | 33 | 10 | 0 | .000 | 0 | 4 | .400 | 48 | 4.8 | 10 | 6 | .600 | 77.0 | .631 |
| Jake Peavy | Oak | sp | 28 | 30 | 2 | .067 | 1 | 16 | .533 | 127 | 4.2 | 20 | 3 | .150 | 109.7 | .620 |
| Tony Pena | Oak | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 33 | 15 | .455 | 20.7 | .642 |
| Joel Peralta | Tex | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 | 32.7 | .643 |
| Troy Percival | LAA | cl | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 | 21.0 | .589 |
| Chris Perez | Mtl | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 3 | .176 | 19.3 | .548 |
| Odalis Perez* | Tor | sp | 32 | 31 | 0 | .000 | 0 | 13 | .419 | 155 | 5.0 | 29 | 8 | .276 | 82.2 | .608 |
| Oliver Perez* | LAA | sp | 27 | 17 | 0 | .000 | 0 | 5 | .294 | 83 | 4.9 | 18 | 6 | .333 | 94.6 | .599 |
| Glen Perkins* | Oak | sp | 26 | 30 | 2 | .067 | 0 | 18 | .600 | 175 | 5.8 | 24 | 2 | .083 | 97.7 | .649 |
| Scott Proctor | Mtl | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 4 | .571 | 26.5 | .571 |
| David Purcey* | ChW | sp | 27 | 16 | 0 | .000 | 0 | 7 | .438 | 77 | 4.8 | 15 | 4 | .267 | 102.4 | .606 |
| Horacio Ramirez* |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 6 | .500 | 21.9 | .643 |
| Ramon Ramirez | Oak | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 1 | .083 | 19.1 | .625 |
| Ramon Ramirez | Det | sp | 26 | 2 | 0 | .000 | 0 | 2 | 1.000 | 16 | 8.0 | 0 | 0 | .000 | 104.5 | .579 |
| Tim Redding | Was | sp | 31 | 33 | 3 | .091 | 0 | 15 | .455 | 183 | 5.5 | 25 | 10 | .400 | 106.8 | .609 |
| Mark Redman* | Sea | sp | 35 | 12 | 0 | .000 | 0 | 4 | .333 | 62 | 5.2 | 10 | 5 | .500 | 90.3 | .601 |
| Chris Resop | Cle | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 4 | .800 | 31.5 | .591 |
| Anthony Reyes | Cle | sp | 27 | 8 | 1 | .125 | 1 | 4 | .500 | 52 | 6.5 | 9 | 7 | .778 | 52.2 | .625 |
| Clayton Richard* | Tex | sp | 25 | 13 | 0 | .000 | 0 | 6 | .462 | 73 | 5.6 | 10 | 1 | .100 | 61.0 | .638 |
| Scott Richmond | Min | sp | 29 | 5 | 1 | .200 | 0 | 2 | .400 | 44 | 8.8 | 1 | 0 | .000 | 107.6 | .686 |
| Juan Rincon | Sea | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 31 | 7 | .226 | 30.8 | .614 |
| Francisco Rodriguez | Tor | cl | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 6 | .750 | 20.5 | .594 |
| Kenny Rogers* | Tex | sp | 44 | 30 | 1 | .033 | 0 | 13 | .433 | 129 | 4.3 | 18 | 6 | .333 | 89.1 | .617 |
| J.C. Romero* | Det | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 4 | .138 | 24.5 | .544 |
| Sergio Romo | Min | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 24.7 | .629 |
| Carlos Rosa | KCR | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 | 26.0 | .546 |
| Leo Rosales | Tor | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 3 | .500 | 11.0 | .364 |
| Josh Rupe | ChW | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 4 | .250 | 40.3 | .568 |
| B.J. Ryan* |   | cl | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 | 20.5 | .608 |
| C.C. Sabathia* | Oak | sp | 28 | 35 | 6 | .171 | 1 | 15 | .429 | 188 | 5.4 | 12 | 5 | .417 | 108.3 | .652 |
| Jeff Samardzija | ChW | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 4 | .444 | 23.5 | .574 |
| Chris Sampson | NYY | mr | 31 | 12 | 0 | .000 | 0 | 8 | .667 | 52 | 4.3 | 10 | 4 | .400 | 55.4 | .661 |
| Duaner Sanchez | Bos | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 3 | .167 | 22.6 | .593 |
| Johan Santana* | Sea | sp | 30 | 32 | 5 | .156 | 2 | 18 | .563 | 143 | 4.5 | 11 | 7 | .636 | 108.0 | .620 |
| Joe Saunders* | LAA | sp | 28 | 31 | 4 | .129 | 2 | 21 | .677 | 163 | 5.3 | 14 | 2 | .143 | 100.1 | .647 |
| Max Scherzer | Tor | mr | 24 | 11 | 1 | .091 | 0 | 9 | .818 | 81 | 7.4 | 16 | 6 | .375 | 115.2 | .575 |
| Scott Schoeneweis* | Det | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 5 | .294 | 23.8 | .601 |
| Bobby Seay* | Bal | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 12 | .414 | 21.2 | .631 |
| Ben Sheets | Oak | sp | 30 | 31 | 2 | .065 | 1 | 15 | .484 | 150 | 4.8 | 24 | 12 | .500 | 105.9 | .635 |
| George Sherrill* | KCR | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 5 | .263 | 22.2 | .594 |
| Scot Shields | Min | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 2 | .125 | 25.2 | .625 |
| Kevin Slowey | Tor | sp | 25 | 30 | 5 | .167 | 0 | 15 | .500 | 141 | 4.7 | 25 | 9 | .360 | 98.2 | .679 |
| Greg Smith* | Det | sp | 25 | 32 | 2 | .063 | 1 | 15 | .469 | 146 | 4.6 | 13 | 4 | .308 | 90.2 | .602 |
| Joe Smith | Tor | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 31 | 14 | .452 | 25.1 | .571 |
| John Smoltz | Mtl | sp | 42 | 9 | 0 | .000 | 0 | 7 | .778 | 35 | 3.9 | 7 | 2 | .286 | 102.4 | .637 |
| Ian Snell | Tex | sp | 27 | 6 | 0 | .000 | 0 | 0 | .000 | 26 | 4.3 | 8 | 1 | .125 | 70.8 | .600 |
| Rafael Soriano | Min | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 4 | .667 | 22.4 | .488 |
| Jeremy Sowers* | Det | sp | 26 | 18 | 3 | .167 | 1 | 13 | .722 | 67 | 3.7 | 8 | 2 | .250 | 96.7 | .637 |
| Justin Speier | NYY | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 3 | .214 | 23.2 | .611 |
| Russ Springer | Min | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 6 | .250 | 23.2 | .598 |
| Mitch Stetter* | Was | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 7 | .304 | 16.6 | .536 |
| Brian Stokes | Was | mr | 29 | 4 | 0 | .000 | 0 | 3 | .750 | 14 | 3.5 | 4 | 1 | .250 | 53.8 | .688 |
| Huston Street | NYY | cl | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 0 | .000 | 22.9 | .622 |
| Jeff Suppan | Bal | sp | 34 | 31 | 1 | .032 | 0 | 14 | .452 | 111 | 3.6 | 30 | 13 | .433 | 97.5 | .603 |
| Jack Taschner* | NYY | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 20.4 | .627 |
| Brad Thompson | KCR | mr | 27 | 4 | 0 | .000 | 0 | 0 | .000 | 21 | 5.3 | 19 | 4 | .211 | 40.5 | .610 |
| Rich Thompson | Mtl | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 61.0 | .557 |
| Ramon Troncoso | Tex | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 29.0 | .648 |
| Justin Verlander | Cle | sp | 26 | 33 | 1 | .030 | 1 | 19 | .576 | 190 | 5.8 | 18 | 9 | .500 | 100.2 | .607 |
| Edinson Volquez | Mtl | sp | 25 | 31 | 0 | .000 | 0 | 18 | .581 | 143 | 4.6 | 38 | 13 | .342 | 101.5 | .587 |
| Chris Volstad | KCR | sp | 22 | 18 | 3 | .167 | 1 | 11 | .611 | 86 | 4.8 | 13 | 2 | .154 | 97.4 | .607 |
| Doug Waechter | ChW | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 4 | .444 | 23.3 | .627 |
| Tim Wakefield | Min | sp | 42 | 31 | 7 | .226 | 1 | 21 | .677 | 131 | 4.2 | 20 | 5 | .250 | 102.8 | .615 |
| Jamie Walker* | Bal | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 6 | .300 | 20.2 | .641 |
| Tyler Walker | Sea | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 6 | .250 | 24.7 | .620 |
| Jarrod Washburn* | Det | sp | 34 | 26 | 0 | .000 | 0 | 10 | .385 | 114 | 4.4 | 15 | 4 | .267 | 81.3 | .609 |
| Chris Waters* | Tor | sp | 28 | 5 | 0 | .000 | 0 | 2 | .400 | 15 | 3.0 | 6 | 4 | .667 | 100.8 | .619 |
| David Weathers | Det | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 4 | .400 | 28.2 | .605 |
| Brandon Webb | Det | sp | 30 | 24 | 3 | .125 | 1 | 15 | .625 | 123 | 5.1 | 29 | 13 | .448 | 113.0 | .617 |
| Kip Wells | Tex | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 38.5 | .558 |
| Dontrelle Willis* | Was | sp | 27 | 10 | 0 | .000 | 0 | 2 | .200 | 61 | 6.1 | 8 | 4 | .500 | 94.7 | .501 |
| C.J. Wilson* | KCR | cl | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 4 | .235 | 24.3 | .578 |
| Randy Wolf* | ChW | sp | 32 | 33 | 3 | .091 | 0 | 15 | .455 | 136 | 4.1 | 19 | 7 | .368 | 101.4 | .611 |
| Brian Wolfe | Mtl | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 9 | .500 | 19.6 | .595 |
| Kerry Wood | Det | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 0 | .000 | 22.4 | .608 |
| Michael Wuertz | Tex | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 3 | .143 | 21.0 | .600 |
| Yasuhiko Yabuta | Cle | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 9.8 | .653 |
| Charlie Zink | Cle | sp | 29 | 2 | 0 | .000 | 0 | 1 | .500 | 8 | 4.0 | 1 | 0 | .000 | 78.0 | .635 |
| Barry Zito* | ChW | sp | 31 | 32 | 0 | .000 | 0 | 10 | .313 | 128 | 4.0 | 26 | 14 | .538 | 102.6 | .559 |
| Joel Zumaya | KCR | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 7 | .500 | 32.0 | .553 |
| Relief |
| Name | Team | P | Age | SVO | S | SV% | BS | BS% | HLD | IR | IRS | IR% | G | GR | GF | NP/G | STR% |
| Alfredo Aceves | Was | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 102.0 | .575 |
| Nick Adenhart | Bal | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 80.7 | .595 |
| Jeremy Affeldt* | Bos | mr | 30 | 3 | 2 | .667 | 1 | .333 | 2 | 23 | 6 | .261 | 24 | 24 | 10 | 19.8 | .621 |
| Jonathan Albaladejo | Min | mr | 26 | 1 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 0 | 8.0 | .625 |
| Matt Albers | Tex | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 17 | 7 | .412 | 33 | 26 | 15 | 47.8 | .579 |
| Jose Arredondo | Cle | mr | 25 | 8 | 4 | .500 | 4 | .500 | 11 | 40 | 10 | .250 | 50 | 50 | 19 | 19.1 | .623 |
| Luis Ayala | Bal | mr | 31 | 5 | 1 | .200 | 4 | .800 | 14 | 50 | 19 | .380 | 60 | 60 | 22 | 19.9 | .611 |
| Brandon Backe | Bal | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 95.7 | .591 |
| Burke Badenhop | KCR | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 11 | 1 | 0 | 85.3 | .593 |
| Cha Seung Baek | NYY | sp | 29 | 1 | 0 | .000 | 1 | 1.000 | 0 | 1 | 1 | 1.000 | 26 | 1 | 1 | 89.8 | .610 |
| Homer Bailey | Tor | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 70.4 | .597 |
| Josh Banks | Mtl | sp | 26 | 1 | 1 | 1.000 | 0 | .000 | 1 | 9 | 5 | .556 | 29 | 15 | 8 | 67.1 | .589 |
| Brian Bass | Bal | mr | 27 | 1 | 1 | 1.000 | 0 | .000 | 2 | 17 | 10 | .588 | 21 | 19 | 9 | 44.8 | .641 |
| Miguel Batista | Bal | mr | 38 | 0 | 0 | .000 | 0 | .000 | 0 | 25 | 11 | .440 | 36 | 22 | 5 | 52.5 | .567 |
| Denny Bautista | Sea | mr | 28 | 2 | 2 | 1.000 | 0 | .000 | 1 | 8 | 3 | .375 | 10 | 10 | 7 | 23.6 | .547 |
| T.J. Beam | LAA | mr | 28 | 0 | 0 | .000 | 0 | .000 | 2 | 10 | 6 | .600 | 7 | 7 | 1 | 38.4 | .599 |
| Josh Beckett | KCR | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 108.2 | .654 |
| Joe Beimel* | Min | mr | 32 | 2 | 1 | .500 | 1 | .500 | 5 | 42 | 8 | .190 | 50 | 50 | 14 | 22.5 | .598 |
| Matt Belisle | Tex | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 67.0 | .667 |
| Joaquin Benoit | Oak | mr | 31 | 2 | 0 | .000 | 1 | .500 | 1 | 6 | 2 | .333 | 12 | 12 | 4 | 9.5 | .509 |
| Jason Bergmann | KCR | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 87.8 | .636 |
| Randor Bierd | Mtl | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 21 | 8 | .381 | 20 | 20 | 10 | 28.5 | .592 |
| Jerry Blevins* | Mtl | mr | 25 | 7 | 7 | 1.000 | 0 | .000 | 11 | 39 | 6 | .154 | 39 | 39 | 17 | 19.0 | .624 |
| Mitchell Boggs | Det | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 86.3 | .548 |
| Jeremy Bonderman | Was | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 102.4 | .612 |
| Eddie Bonine | Tex | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 101.3 | .672 |
| Michael Bowden | NYY | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 90.6 | .611 |
| Dallas Braden* | Mtl | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 13 | 4 | .308 | 25 | 12 | 5 | 71.4 | .635 |
| Chad Bradford | Det | mr | 34 | 8 | 2 | .250 | 5 | .625 | 18 | 26 | 8 | .308 | 60 | 60 | 23 | 22.1 | .677 |
| Craig Breslow* | NYY | mr | 28 | 6 | 3 | .500 | 2 | .333 | 11 | 31 | 6 | .194 | 48 | 48 | 21 | 21.3 | .600 |
| Doug Brocail | Tor | mr | 42 | 6 | 3 | .500 | 3 | .500 | 3 | 75 | 31 | .413 | 68 | 68 | 25 | 26.0 | .623 |
| Andrew Brown | Mtl | mr | 28 | 5 | 3 | .600 | 2 | .400 | 9 | 27 | 7 | .259 | 38 | 38 | 24 | 23.6 | .596 |
| Brian Bruney |   | mr | 27 | 5 | 3 | .600 | 2 | .400 | 6 | 22 | 8 | .364 | 31 | 26 | 12 | 38.5 | .589 |
| Clay Buchholz | Cle | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 | 90.8 | .594 |
| Taylor Buchholz | ChW | mr | 27 | 2 | 1 | .500 | 1 | .500 | 0 | 10 | 3 | .300 | 7 | 7 | 4 | 25.9 | .630 |
| Bryan Bullington | Bos | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 1 | 1 | 0 | 31.0 | .645 |
| Brian Burres* | Tex | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 31 | 1 | 0 | 88.7 | .616 |
| Paul Byrd | Tor | sp | 38 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 89.6 | .657 |
| Daniel Cabrera | Bal | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 104.6 | .573 |
| Matt Cain | NYY | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 100.2 | .602 |
| Shawn Camp | Oak | mr | 33 | 3 | 1 | .333 | 2 | .667 | 6 | 31 | 12 | .387 | 40 | 40 | 19 | 20.0 | .650 |
| Jorge Campillo | Bos | sp | 30 | 1 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 33 | 3 | 1 | 80.9 | .628 |
| Matt Capps | Sea | cl | 25 | 20 | 15 | .750 | 5 | .250 | 1 | 43 | 8 | .186 | 53 | 53 | 44 | 19.2 | .667 |
| Vinnie Chulk | Was | mr | 30 | 2 | 0 | .000 | 1 | .500 | 0 | 9 | 4 | .444 | 8 | 8 | 2 | 23.6 | .661 |
| Tyler Clippard | Sea | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 78.5 | .522 |
| Todd Coffey | Cle | mr | 28 | 0 | 0 | .000 | 0 | .000 | 2 | 7 | 1 | .143 | 10 | 10 | 6 | 19.2 | .563 |
| Phil Coke* | Bal | mr | 26 | 2 | 2 | 1.000 | 0 | .000 | 2 | 7 | 2 | .286 | 11 | 11 | 8 | 17.4 | .712 |
| Bartolo Colon | Sea | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 0 | 0 | 99.5 | .668 |
| Francisco Cordero | Tex | cl | 34 | 31 | 25 | .806 | 6 | .194 | 0 | 49 | 15 | .306 | 52 | 52 | 44 | 20.9 | .586 |
| Lance Cormier | Oak | mr | 28 | 2 | 2 | 1.000 | 0 | .000 | 1 | 28 | 9 | .321 | 38 | 33 | 14 | 40.1 | .608 |
| Manuel Corpas | NYY | mr | 26 | 8 | 2 | .250 | 6 | .750 | 13 | 58 | 23 | .397 | 59 | 59 | 26 | 21.3 | .637 |
| Kevin Correia | Sea | sp | 28 | 1 | 1 | 1.000 | 0 | .000 | 2 | 7 | 1 | .143 | 23 | 4 | 2 | 77.8 | .603 |
| Juan Cruz | Cle | mr | 30 | 4 | 0 | .000 | 4 | 1.000 | 10 | 45 | 18 | .400 | 52 | 52 | 13 | 24.4 | .553 |
| Johnny Cueto | Sea | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 99.7 | .597 |
| Eulogio De La Cruz | ChW | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 5 | 5 | 1 | 44.8 | .504 |
| Jorge De La Rosa* | Was | sp | 28 | 2 | 2 | 1.000 | 0 | .000 | 1 | 5 | 0 | .000 | 31 | 5 | 2 | 91.4 | .581 |
| Manny Delcarmen | Cle | mr | 27 | 39 | 37 | .949 | 2 | .051 | 1 | 29 | 8 | .276 | 59 | 59 | 52 | 14.5 | .624 |
| Ryan Dempster | LAA | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 103.8 | .614 |
| Joey Devine | Bos | mr | 25 | 9 | 9 | 1.000 | 0 | .000 | 8 | 37 | 10 | .270 | 46 | 46 | 25 | 32.0 | .616 |
| R.A. Dickey | Min | mr | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 94.9 | .603 |
| Mark DiFelice | Bos | mr | 32 | 3 | 0 | .000 | 1 | .333 | 7 | 14 | 4 | .286 | 20 | 20 | 5 | 16.6 | .628 |
| Tim Dillard | Min | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 | 25.0 | .520 |
| Octavio Dotel | Mtl | mr | 35 | 41 | 32 | .780 | 8 | .195 | 1 | 47 | 12 | .255 | 60 | 60 | 54 | 19.4 | .631 |
| Scott Downs* | LAA | mr | 33 | 18 | 16 | .889 | 2 | .111 | 10 | 48 | 12 | .250 | 65 | 65 | 40 | 21.7 | .634 |
| Justin Duchscherer | Cle | sp | 31 | 1 | 1 | 1.000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 1 | 1 | 91.9 | .662 |
| Zach Duke* | Tor | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 1 | 1 | 82.9 | .610 |
| Chad Durbin | KCR | mr | 31 | 8 | 3 | .375 | 4 | .500 | 12 | 52 | 20 | .385 | 67 | 67 | 28 | 22.3 | .594 |
| Adam Eaton | Bal | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 0 | 0 | 96.9 | .605 |
| Scott Elarton | LAA | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 0 | 15.5 | .742 |
| Alan Embree* | Sea | mr | 39 | 2 | 0 | .000 | 2 | 1.000 | 10 | 65 | 23 | .354 | 70 | 70 | 20 | 25.8 | .591 |
| Shawn Estes* | Sea | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 89.8 | .578 |
| Dana Eveland* | LAA | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 96.8 | .592 |
| Scott Eyre* | LAA | mr | 37 | 4 | 1 | .250 | 3 | .750 | 4 | 26 | 5 | .192 | 32 | 32 | 15 | 19.3 | .667 |
| Kyle Farnsworth | Mtl | mr | 33 | 1 | 1 | 1.000 | 0 | .000 | 0 | 15 | 1 | .067 | 17 | 17 | 4 | 23.9 | .639 |
| Ryan Feierabend* | ChW | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 | 80.4 | .603 |
| Pedro Feliciano* | NYY | mr | 32 | 4 | 2 | .500 | 2 | .500 | 9 | 50 | 12 | .240 | 52 | 52 | 9 | 21.1 | .611 |
| Nelson Figueroa | KCR | mr | 35 | 1 | 0 | .000 | 1 | 1.000 | 1 | 6 | 5 | .833 | 12 | 9 | 2 | 41.8 | .556 |
| Keith Foulke | Was | mr | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 4 | 4 | 2 | 19.8 | .544 |
| Jeff Francis* | ChW | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 | 102.0 | .626 |
| Ryan Franklin | Det | mr | 36 | 3 | 2 | .667 | 1 | .333 | 7 | 35 | 15 | .429 | 43 | 43 | 17 | 21.2 | .602 |
| Eric Gagne | Tor | mr | 33 | 3 | 2 | .667 | 1 | .333 | 1 | 28 | 13 | .464 | 29 | 29 | 14 | 22.7 | .582 |
| Freddy Garcia | Min | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 97.3 | .598 |
| Jaime Garcia* | Sea | mr | 22 | 3 | 0 | .000 | 1 | .333 | 2 | 10 | 3 | .300 | 16 | 15 | 8 | 36.8 | .558 |
| Jon Garland | Mtl | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 88.1 | .623 |
| Matt Garza | Bal | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 99.7 | .628 |
| Geoff Geary | LAA | mr | 32 | 4 | 2 | .500 | 1 | .250 | 8 | 33 | 10 | .303 | 49 | 49 | 16 | 22.7 | .610 |
| Josh Geer | ChW | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 92.7 | .641 |
| Franklyn German | Min | mr | 29 | 0 | 0 | .000 | 0 | .000 | 2 | 18 | 4 | .222 | 13 | 13 | 4 | 26.1 | .546 |
| Justin Germano | Tex | sp | 26 | 1 | 1 | 1.000 | 0 | .000 | 1 | 7 | 0 | .000 | 10 | 8 | 3 | 54.2 | .646 |
| Matt Ginter | Min | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 98.0 | .719 |
| Gary Glover | Tor | mr | 32 | 2 | 2 | 1.000 | 0 | .000 | 4 | 39 | 11 | .282 | 42 | 42 | 14 | 33.3 | .638 |
| Jimmy Gobble* | Tor | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 15 | 4 | .267 | 10 | 9 | 3 | 15.6 | .545 |
| Edgar Gonzalez | LAA | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 0 | 31.0 | .613 |
| Gio Gonzalez* | Sea | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 12 | 1 | 1 | 90.8 | .541 |
| Mike Gonzalez* | Cle | cl | 31 | 3 | 0 | .000 | 3 | 1.000 | 4 | 21 | 10 | .476 | 28 | 28 | 7 | 15.2 | .690 |
| Tom Gorzelanny* | Sea | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 91.8 | .547 |
| Sean Green | ChW | mr | 30 | 10 | 6 | .600 | 4 | .400 | 12 | 42 | 8 | .190 | 59 | 59 | 22 | 22.5 | .601 |
| Zack Greinke | Bos | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 103.7 | .650 |
| Matt Guerrier | Cle | mr | 30 | 6 | 1 | .167 | 2 | .333 | 10 | 34 | 14 | .412 | 56 | 56 | 17 | 18.6 | .603 |
| Charlie Haeger | Cle | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 3 | 3 | 2 | 36.0 | .528 |
| Jason Hammel | ChW | mr | 26 | 4 | 1 | .250 | 3 | .750 | 3 | 50 | 19 | .380 | 47 | 47 | 27 | 29.0 | .609 |
| Mike Hampton* | Cle | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 | 88.1 | .633 |
| Joel Hanrahan | Tex | mr | 27 | 6 | 4 | .667 | 1 | .167 | 9 | 48 | 13 | .271 | 67 | 67 | 28 | 30.0 | .615 |
| J.A. Happ* | LAA | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 90.2 | .557 |
| Aaron Harang | Tor | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 97.9 | .639 |
| Aaron Heilman | Tor | mr | 30 | 5 | 1 | .200 | 4 | .800 | 2 | 19 | 10 | .526 | 29 | 29 | 7 | 24.6 | .538 |
| Mark Hendrickson* | Was | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 26 | 4 | 3 | 84.7 | .627 |
| Clay Hensley | Was | mr | 29 | 2 | 0 | .000 | 0 | .000 | 1 | 5 | 1 | .200 | 16 | 12 | 6 | 39.1 | .566 |
| Felix Hernandez | Min | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 108.2 | .593 |
| Alex Hinshaw* | NYY | mr | 26 | 2 | 0 | .000 | 1 | .500 | 1 | 17 | 3 | .176 | 16 | 16 | 6 | 22.6 | .573 |
| Luke Hochevar | NYY | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 94.6 | .610 |
| J.P. Howell* | Bos | mr | 26 | 20 | 17 | .850 | 3 | .150 | 6 | 39 | 23 | .590 | 56 | 56 | 37 | 22.0 | .582 |
| Tim Hudson | Det | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 98.3 | .617 |
| Jason Isringhausen | Oak | cl | 36 | 1 | 0 | .000 | 1 | 1.000 | 1 | 6 | 4 | .667 | 4 | 4 | 1 | 11.8 | .511 |
| Edwin Jackson | Min | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 90.5 | .603 |
| Zach Jackson* | ChW | sp | 26 | 2 | 2 | 1.000 | 0 | .000 | 1 | 32 | 14 | .438 | 25 | 25 | 16 | 37.9 | .634 |
| Chuck James* | Sea | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 96.0 | .590 |
| Bobby Jenks | KCR | cl | 28 | 37 | 35 | .946 | 1 | .027 | 0 | 29 | 6 | .207 | 61 | 61 | 57 | 15.0 | .660 |
| Jason Johnson | Was | mr | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 92.8 | .617 |
| Josh Johnson | Min | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 | 100.7 | .614 |
| Todd Jones | Mtl | cl | 41 | 2 | 1 | .500 | 0 | .000 | 1 | 10 | 6 | .600 | 16 | 16 | 8 | 22.1 | .623 |
| Jorge Julio | Oak | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 3 | 10 | 2 | .200 | 25 | 25 | 10 | 26.0 | .587 |
| Jair Jurrjens | Mtl | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 99.6 | .623 |
| Scott Kazmir* | Bos | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 99.6 | .605 |
| Kyle Kendrick | Det | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 91.5 | .597 |
| Logan Kensing | Was | mr | 26 | 0 | 0 | .000 | 0 | .000 | 4 | 43 | 12 | .279 | 38 | 38 | 11 | 26.5 | .559 |
| Masa Kobayashi | Bal | mr | 35 | 1 | 0 | .000 | 1 | 1.000 | 2 | 37 | 9 | .243 | 47 | 47 | 24 | 19.7 | .676 |
| Eddie Kunz | ChW | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 6 | 6 | 3 | 20.8 | .536 |
| Hong-Chih Kuo* | Bos | mr | 27 | 7 | 6 | .857 | 1 | .143 | 1 | 37 | 12 | .324 | 46 | 43 | 21 | 38.5 | .647 |
| John Lackey | Cle | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 | 98.4 | .647 |
| John Lannan* | Was | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 1 | 1 | 96.9 | .574 |
| Brandon League | Min | mr | 26 | 3 | 0 | .000 | 2 | .667 | 0 | 31 | 14 | .452 | 29 | 29 | 13 | 25.8 | .610 |
| Wil Ledezma* | Was | mr | 28 | 1 | 1 | 1.000 | 0 | .000 | 1 | 9 | 2 | .222 | 16 | 8 | 6 | 63.7 | .529 |
| Jensen Lewis | Cle | cl | 25 | 2 | 1 | .500 | 1 | .500 | 7 | 31 | 8 | .258 | 49 | 49 | 6 | 25.0 | .614 |
| Brad Lidge | ChW | cl | 32 | 1 | 0 | .000 | 1 | 1.000 | 0 | 7 | 1 | .143 | 5 | 5 | 0 | 31.4 | .567 |
| Mike Lincoln | Sea | mr | 34 | 9 | 3 | .333 | 4 | .444 | 4 | 51 | 25 | .490 | 65 | 65 | 18 | 28.1 | .620 |
| Scott Linebrink | LAA | mr | 32 | 18 | 14 | .778 | 4 | .222 | 4 | 23 | 5 | .217 | 48 | 48 | 24 | 19.2 | .658 |
| Francisco Liriano* | Min | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 101.3 | .605 |
| Wes Littleton | Cle | mr | 26 | 0 | 0 | .000 | 0 | .000 | 3 | 7 | 3 | .429 | 13 | 13 | 5 | 17.2 | .594 |
| Esteban Loaiza | Oak | mr | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 85.0 | .682 |
| Boone Logan* | ChW | mr | 24 | 8 | 6 | .750 | 2 | .250 | 6 | 31 | 15 | .484 | 40 | 40 | 26 | 21.1 | .633 |
| Kyle Lohse | Bos | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 87.6 | .636 |
| Braden Looper | Tex | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 34 | 1 | 1 | 88.6 | .636 |
| Aquilino Lopez | Was | mr | 34 | 5 | 1 | .200 | 4 | .800 | 1 | 17 | 8 | .471 | 34 | 34 | 21 | 25.5 | .676 |
| Javier Lopez* | Tex | mr | 31 | 5 | 4 | .800 | 1 | .200 | 11 | 40 | 7 | .175 | 51 | 51 | 20 | 22.8 | .611 |
| Mark Lowe | Bos | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 7 | 3 | .429 | 16 | 16 | 6 | 21.6 | .542 |
| Ryan Madson | NYY | mr | 28 | 7 | 2 | .286 | 3 | .429 | 9 | 35 | 20 | .571 | 59 | 59 | 21 | 22.5 | .628 |
| Charlie Manning* | LAA | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 4 | 17 | 5 | .294 | 34 | 34 | 16 | 22.8 | .530 |
| Carlos Marmol | Bal | mr | 26 | 32 | 28 | .875 | 4 | .125 | 0 | 27 | 7 | .259 | 50 | 50 | 44 | 21.5 | .576 |
| Damaso Marte* | Cle | mr | 34 | 9 | 1 | .111 | 3 | .333 | 16 | 49 | 16 | .327 | 60 | 60 | 15 | 16.6 | .592 |
| Shairon Martis | KCR | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 2 | 2 | 76.1 | .601 |
| Tom Mastny | Tex | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 93.8 | .605 |
| Doug Mathis | Tor | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 47.5 | .600 |
| Daisuke Matsuzaka | NYY | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 112.1 | .573 |
| Kyle McClellan | Bal | mr | 25 | 2 | 2 | 1.000 | 0 | .000 | 4 | 53 | 24 | .453 | 50 | 50 | 20 | 24.5 | .609 |
| Dustin McGowan | Cle | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 | 96.0 | .635 |
| Gil Meche | KCR | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 106.6 | .624 |
| Andrew Miller* | LAA | sp | 24 | 1 | 0 | .000 | 1 | 1.000 | 1 | 6 | 3 | .500 | 25 | 6 | 2 | 74.2 | .594 |
| Jim Miller | Bos | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 2 | 2 | 0 | 15.0 | .667 |
| Trever Miller* | Tor | mr | 36 | 3 | 0 | .000 | 2 | .667 | 5 | 24 | 6 | .250 | 27 | 27 | 10 | 21.3 | .571 |
| Kevin Millwood | Mtl | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 102.7 | .655 |
| Zach Miner | Det | mr | 27 | 2 | 1 | .500 | 1 | .500 | 1 | 23 | 4 | .174 | 35 | 30 | 13 | 38.0 | .626 |
| Brian Moehler | Tex | sp | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 93.2 | .639 |
| Brandon Morrow | Was | mr | 24 | 7 | 4 | .571 | 3 | .429 | 12 | 28 | 3 | .107 | 40 | 37 | 8 | 33.7 | .600 |
| Charlie Morton | Det | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 82.2 | .564 |
| Guillermo Mota |   | mr | 35 | 4 | 2 | .500 | 2 | .500 | 7 | 40 | 13 | .325 | 53 | 53 | 16 | 26.2 | .582 |
| Jason Motte | Was | mr | 27 | 4 | 1 | .250 | 2 | .500 | 2 | 10 | 2 | .200 | 8 | 8 | 3 | 24.1 | .617 |
| Edward Mujica | Min | mr | 25 | 3 | 1 | .333 | 0 | .000 | 1 | 7 | 2 | .286 | 14 | 14 | 8 | 25.5 | .658 |
| Mike Mussina | Bos | sp | 40 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 92.2 | .681 |
| Brett Myers | Oak | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 104.7 | .625 |
| Joe Nelson | Bos | mr | 34 | 19 | 15 | .789 | 3 | .158 | 5 | 38 | 11 | .289 | 54 | 54 | 33 | 24.0 | .600 |
| Jonathon Niese* | ChW | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 | 94.0 | .603 |
| Fernando Nieve | Bos | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 2 | 2 | 2 | 25.5 | .510 |
| Dustin Nippert | ChW | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 96.2 | .617 |
| Hideki Okajima* | Was | mr | 33 | 9 | 5 | .556 | 4 | .444 | 9 | 37 | 10 | .270 | 31 | 31 | 16 | 22.0 | .592 |
| Darren Oliver* | Oak | mr | 38 | 19 | 12 | .632 | 4 | .211 | 10 | 37 | 8 | .216 | 57 | 57 | 32 | 16.6 | .668 |
| Garrett Olson* | LAA | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 92.5 | .597 |
| Vicente Padilla | KCR | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 99.0 | .612 |
| Matt Palmer | Tor | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 50.5 | .535 |
| Jonathan Papelbon | Min | cl | 28 | 40 | 35 | .875 | 5 | .125 | 0 | 36 | 6 | .167 | 65 | 65 | 56 | 19.5 | .696 |
| Manny Parra* | NYY | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 1 | 0 | 89.8 | .592 |
| John Parrish* | Mtl | mr | 31 | 1 | 0 | .000 | 1 | 1.000 | 2 | 12 | 5 | .417 | 16 | 14 | 6 | 28.3 | .549 |
| Scott Patterson | Cle | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 4 | 4 | 0 | 12.0 | .521 |
| Carl Pavano | Cle | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 | 77.0 | .631 |
| Jake Peavy | Oak | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 109.7 | .620 |
| Tony Pena | Oak | mr | 27 | 7 | 3 | .429 | 2 | .286 | 12 | 40 | 14 | .350 | 61 | 61 | 16 | 20.7 | .642 |
| Joel Peralta | Tex | mr | 33 | 1 | 0 | .000 | 1 | 1.000 | 0 | 30 | 9 | .300 | 40 | 40 | 18 | 32.7 | .643 |
| Troy Percival | LAA | cl | 39 | 15 | 10 | .667 | 5 | .333 | 6 | 37 | 16 | .432 | 46 | 46 | 25 | 21.0 | .589 |
| Chris Perez | Mtl | mr | 23 | 1 | 1 | 1.000 | 0 | .000 | 9 | 24 | 3 | .125 | 31 | 31 | 11 | 19.3 | .548 |
| Odalis Perez* | Tor | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 82.2 | .608 |
| Oliver Perez* | LAA | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 94.6 | .599 |
| Glen Perkins* | Oak | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 97.7 | .649 |
| Scott Proctor | Mtl | mr | 32 | 2 | 0 | .000 | 2 | 1.000 | 0 | 27 | 11 | .407 | 25 | 25 | 7 | 26.5 | .571 |
| David Purcey* | ChW | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 102.4 | .606 |
| Horacio Ramirez* |   | mr | 29 | 2 | 1 | .500 | 1 | .500 | 4 | 41 | 19 | .463 | 34 | 34 | 15 | 21.9 | .643 |
| Ramon Ramirez | Oak | mr | 27 | 25 | 19 | .760 | 6 | .240 | 11 | 56 | 14 | .250 | 66 | 66 | 38 | 19.1 | .625 |
| Ramon Ramirez | Det | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 104.5 | .579 |
| Tim Redding | Was | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 106.8 | .609 |
| Mark Redman* | Sea | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 90.3 | .601 |
| Chris Resop | Cle | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 0 | .000 | 8 | 8 | 2 | 31.5 | .591 |
| Anthony Reyes | Cle | sp | 27 | 1 | 0 | .000 | 0 | .000 | 0 | 7 | 3 | .429 | 18 | 10 | 4 | 52.2 | .625 |
| Clayton Richard* | Tex | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 13 | 4 | .308 | 25 | 12 | 6 | 61.0 | .638 |
| Scott Richmond | Min | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 107.6 | .686 |
| Juan Rincon | Sea | mr | 30 | 1 | 0 | .000 | 0 | .000 | 3 | 50 | 19 | .380 | 53 | 53 | 23 | 30.8 | .614 |
| Francisco Rodriguez | Tor | cl | 27 | 28 | 24 | .857 | 4 | .143 | 1 | 50 | 14 | .280 | 71 | 71 | 59 | 20.5 | .594 |
| Kenny Rogers* | Tex | sp | 44 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 89.1 | .617 |
| J.C. Romero* | Det | mr | 33 | 10 | 4 | .400 | 4 | .400 | 8 | 37 | 9 | .243 | 59 | 59 | 23 | 24.5 | .544 |
| Sergio Romo | Min | mr | 26 | 4 | 2 | .500 | 2 | .500 | 3 | 18 | 5 | .278 | 25 | 25 | 11 | 24.7 | .629 |
| Carlos Rosa | KCR | mr | 24 | 0 | 0 | .000 | 0 | .000 | 1 | 6 | 1 | .167 | 5 | 5 | 2 | 26.0 | .546 |
| Leo Rosales | Tor | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 3 | 1.000 | 2 | 2 | 0 | 11.0 | .364 |
| Josh Rupe | ChW | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 38 | 16 | .421 | 37 | 37 | 18 | 40.3 | .568 |
| B.J. Ryan* |   | cl | 33 | 46 | 39 | .848 | 7 | .152 | 0 | 37 | 11 | .297 | 62 | 62 | 53 | 20.5 | .608 |
| C.C. Sabathia* | Oak | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 0 | 0 | 108.3 | .652 |
| Jeff Samardzija | ChW | mr | 24 | 20 | 14 | .700 | 6 | .300 | 2 | 20 | 6 | .300 | 28 | 28 | 20 | 23.5 | .574 |
| Chris Sampson | NYY | mr | 31 | 0 | 0 | .000 | 0 | .000 | 1 | 15 | 3 | .200 | 31 | 19 | 4 | 55.4 | .661 |
| Duaner Sanchez | Bos | mr | 29 | 2 | 1 | .500 | 1 | .500 | 5 | 33 | 10 | .303 | 39 | 39 | 17 | 22.6 | .593 |
| Johan Santana* | Sea | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 108.0 | .620 |
| Joe Saunders* | LAA | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 100.1 | .647 |
| Max Scherzer | Tor | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 0 | 0 | 115.2 | .575 |
| Scott Schoeneweis* | Det | mr | 35 | 2 | 1 | .500 | 1 | .500 | 5 | 51 | 15 | .294 | 47 | 47 | 14 | 23.8 | .601 |
| Bobby Seay* | Bal | mr | 31 | 7 | 0 | .000 | 4 | .571 | 11 | 48 | 19 | .396 | 51 | 51 | 15 | 21.2 | .631 |
| Ben Sheets | Oak | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 105.9 | .635 |
| George Sherrill* | KCR | cl | 32 | 13 | 5 | .385 | 7 | .538 | 15 | 44 | 18 | .409 | 56 | 56 | 17 | 22.2 | .594 |
| Scot Shields | Min | mr | 33 | 2 | 1 | .500 | 1 | .500 | 14 | 52 | 8 | .154 | 58 | 58 | 16 | 25.2 | .625 |
| Kevin Slowey | Tor | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 98.2 | .679 |
| Greg Smith* | Det | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 90.2 | .602 |
| Joe Smith | Tor | mr | 25 | 8 | 5 | .625 | 3 | .375 | 8 | 49 | 15 | .306 | 56 | 56 | 15 | 25.1 | .571 |
| John Smoltz | Mtl | sp | 42 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 102.4 | .637 |
| Ian Snell | Tex | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 70.8 | .600 |
| Rafael Soriano | Min | mr | 29 | 1 | 0 | .000 | 0 | .000 | 1 | 10 | 6 | .600 | 11 | 11 | 4 | 22.4 | .488 |
| Jeremy Sowers* | Det | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 96.7 | .637 |
| Justin Speier | NYY | mr | 35 | 1 | 1 | 1.000 | 0 | .000 | 2 | 47 | 15 | .319 | 47 | 47 | 19 | 23.2 | .611 |
| Russ Springer | Min | mr | 40 | 4 | 0 | .000 | 4 | 1.000 | 9 | 49 | 23 | .469 | 53 | 53 | 20 | 23.2 | .598 |
| Mitch Stetter* | Was | mr | 28 | 7 | 1 | .143 | 2 | .286 | 12 | 25 | 8 | .320 | 33 | 33 | 7 | 16.6 | .536 |
| Brian Stokes | Was | mr | 29 | 0 | 0 | .000 | 0 | .000 | 2 | 7 | 1 | .143 | 9 | 5 | 2 | 53.8 | .688 |
| Huston Street | NYY | cl | 25 | 32 | 25 | .781 | 7 | .219 | 1 | 25 | 4 | .160 | 55 | 55 | 44 | 22.9 | .622 |
| Jeff Suppan | Bal | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 97.5 | .603 |
| Jack Taschner* | NYY | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 7 | 4 | .571 | 5 | 5 | 4 | 20.4 | .627 |
| Brad Thompson | KCR | mr | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 16 | 7 | .438 | 30 | 26 | 15 | 40.5 | .610 |
| Rich Thompson | Mtl | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 1 | 1 | 0 | 61.0 | .557 |
| Ramon Troncoso | Tex | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 1 | .333 | 5 | 5 | 2 | 29.0 | .648 |
| Justin Verlander | Cle | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 100.2 | .607 |
| Edinson Volquez | Mtl | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 101.5 | .587 |
| Chris Volstad | KCR | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 97.4 | .607 |
| Doug Waechter | ChW | mr | 28 | 5 | 3 | .600 | 2 | .400 | 6 | 23 | 7 | .304 | 37 | 37 | 21 | 23.3 | .627 |
| Tim Wakefield | Min | sp | 42 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 102.8 | .615 |
| Jamie Walker* | Bal | mr | 37 | 1 | 0 | .000 | 1 | 1.000 | 0 | 45 | 20 | .444 | 37 | 37 | 9 | 20.2 | .641 |
| Tyler Walker | Sea | mr | 33 | 8 | 1 | .125 | 5 | .625 | 10 | 46 | 15 | .326 | 69 | 69 | 30 | 24.7 | .620 |
| Jarrod Washburn* | Det | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 81.3 | .609 |
| Chris Waters* | Tor | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 100.8 | .619 |
| David Weathers | Det | mr | 39 | 1 | 1 | 1.000 | 0 | .000 | 2 | 29 | 15 | .517 | 37 | 37 | 16 | 28.2 | .605 |
| Brandon Webb | Det | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 | 113.0 | .617 |
| Kip Wells | Tex | mr | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 1 | 38.5 | .558 |
| Dontrelle Willis* | Was | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 | 94.7 | .501 |
| C.J. Wilson* | KCR | cl | 28 | 4 | 1 | .250 | 3 | .750 | 10 | 40 | 10 | .250 | 52 | 52 | 17 | 24.3 | .578 |
| Randy Wolf* | ChW | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 101.4 | .611 |
| Brian Wolfe | Mtl | mr | 28 | 3 | 1 | .333 | 1 | .333 | 6 | 15 | 7 | .467 | 25 | 25 | 4 | 19.6 | .595 |
| Kerry Wood | Det | cl | 32 | 34 | 26 | .765 | 8 | .235 | 3 | 36 | 13 | .361 | 58 | 58 | 46 | 22.4 | .608 |
| Michael Wuertz | Tex | mr | 30 | 7 | 3 | .429 | 3 | .429 | 4 | 23 | 11 | .478 | 40 | 40 | 19 | 21.0 | .600 |
| Yasuhiko Yabuta | Cle | mr | 36 | 0 | 0 | .000 | 0 | .000 | 1 | 4 | 1 | .250 | 5 | 5 | 2 | 9.8 | .653 |
| Charlie Zink | Cle | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 78.0 | .635 |
| Barry Zito* | ChW | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 102.6 | .559 |
| Joel Zumaya | KCR | mr | 24 | 1 | 0 | .000 | 1 | 1.000 | 1 | 23 | 11 | .478 | 27 | 27 | 9 | 32.0 | .553 |