League pitching register -- 2007 American League
Regular season -- as of 10/29/2007
| Primary |
| Name | Team | P | Age | ERA | W | L | S | G | GS | CG | SHO | INN | H | R | ER | BB | K | HR | GDP |
| Jeremy Accardo | ChW | mr | 24 | 4.68 | 3 | 4 | 2 | 43 | 0 | 0 | 0 | 57.2 | 68 | 31 | 30 | 16 | 49 | 7 | 3 |
| Jeremy Affeldt* | Bos | mr | 27 | 4.37 | 5 | 2 | 0 | 30 | 11 | 0 | 0 | 82.1 | 83 | 45 | 40 | 41 | 38 | 15 | 5 |
| Cha Seung Baek | NYY | sp | 26 | 3.92 | 2 | 2 | 0 | 6 | 6 | 1 | 0 | 41.1 | 30 | 19 | 18 | 12 | 35 | 9 | 4 |
| Danys Baez | Mtl | mr | 28 | 5.25 | 1 | 3 | 1 | 57 | 0 | 0 | 0 | 85.2 | 100 | 55 | 50 | 22 | 49 | 8 | 6 |
| Kevin Barry | Sea | mr | 27 | 8.44 | 0 | 1 | 2 | 8 | 0 | 0 | 0 | 5.1 | 6 | 6 | 5 | 4 | 7 | 2 | 0 |
| Miguel Batista | Sea | sp | 35 | 5.90 | 9 | 10 | 0 | 26 | 25 | 3 | 0 | 157.0 | 180 | 109 | 103 | 66 | 75 | 18 | 22 |
| Rick Bauer | Sea | mr | 29 | 1.49 | 3 | 4 | 2 | 56 | 0 | 0 | 0 | 90.2 | 72 | 21 | 15 | 27 | 46 | 6 | 19 |
| Jonah Bayliss | ChW | mr | 25 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
| Josh Beckett | KCR | sp | 26 | 3.98 | 12 | 8 | 0 | 33 | 33 | 2 | 0 | 217.1 | 182 | 100 | 96 | 58 | 162 | 42 | 18 |
| Joe Beimel* | Det | mr | 29 | 3.14 | 1 | 3 | 1 | 32 | 0 | 0 | 0 | 43.0 | 35 | 15 | 15 | 6 | 19 | 3 | 2 |
| Armando Benitez | ChW | cl | 33 | 7.36 | 2 | 4 | 1 | 19 | 0 | 0 | 0 | 22.0 | 31 | 21 | 18 | 16 | 18 | 7 | 2 |
| Joaquin Benoit | Tor | mr | 28 | 3.35 | 8 | 3 | 2 | 62 | 0 | 0 | 0 | 137.0 | 115 | 56 | 51 | 53 | 154 | 12 | 6 |
| Kris Benson | ChW | sp | 31 | 4.74 | 10 | 12 | 0 | 32 | 32 | 2 | 1 | 209.0 | 231 | 126 | 110 | 57 | 99 | 44 | 25 |
| Jason Bergmann | KCR | mr | 24 | 0.00 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 1.2 | 1 | 0 | 0 | 2 | 4 | 0 | 0 |
| Adam Bernero | Oak | sp | 29 | 3.21 | 0 | 1 | 0 | 3 | 3 | 0 | 0 | 14.0 | 12 | 5 | 5 | 4 | 11 | 1 | 1 |
| Rafael Betancourt | Oak | mr | 31 | 1.30 | 3 | 4 | 28 | 52 | 0 | 0 | 0 | 69.1 | 51 | 13 | 10 | 6 | 45 | 2 | 1 |
| Jeremy Bonderman | Oak | sp | 23 | 3.75 | 15 | 8 | 0 | 34 | 34 | 5 | 1 | 242.2 | 239 | 116 | 101 | 65 | 231 | 16 | 23 |
| Joe Borowski | KCR | cl | 35 | 3.34 | 2 | 2 | 3 | 64 | 0 | 0 | 0 | 94.1 | 90 | 43 | 35 | 35 | 106 | 9 | 4 |
| Chad Bradford | Bos | mr | 31 | 2.86 | 4 | 5 | 6 | 58 | 0 | 0 | 0 | 85.0 | 90 | 33 | 27 | 19 | 64 | 3 | 7 |
| Bill Bray* | Bos | mr | 23 | 3.60 | 3 | 0 | 2 | 13 | 0 | 0 | 0 | 25.0 | 25 | 11 | 10 | 13 | 16 | 2 | 6 |
| Craig Breslow* | Bal | mr | 25 | 8.44 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 5.1 | 8 | 5 | 5 | 5 | 3 | 1 | 1 |
| Chris Britton | Cle | mr | 23 | 4.08 | 0 | 2 | 1 | 28 | 0 | 0 | 0 | 46.1 | 40 | 22 | 21 | 15 | 32 | 2 | 0 |
| Doug Brocail | KCR | mr | 39 | 1.79 | 3 | 0 | 0 | 29 | 0 | 0 | 0 | 45.1 | 42 | 13 | 9 | 13 | 39 | 1 | 2 |
| Brian Bruney | Cle | mr | 24 | 3.16 | 1 | 1 | 1 | 17 | 0 | 0 | 0 | 25.2 | 16 | 13 | 9 | 16 | 23 | 1 | 6 |
| Taylor Buchholz | ChW | sp | 24 | 4.87 | 8 | 1 | 1 | 56 | 0 | 0 | 0 | 98.0 | 97 | 57 | 53 | 22 | 60 | 21 | 8 |
| Paul Byrd | Tor | sp | 35 | 5.43 | 9 | 18 | 0 | 35 | 32 | 4 | 3 | 185.2 | 244 | 125 | 112 | 48 | 79 | 26 | 16 |
| Daniel Cabrera | Cle | sp | 25 | 5.59 | 7 | 15 | 0 | 30 | 30 | 0 | 0 | 164.1 | 168 | 116 | 102 | 120 | 191 | 13 | 15 |
| Matt Cain | NYY | sp | 21 | 4.30 | 10 | 11 | 0 | 32 | 32 | 1 | 0 | 190.2 | 172 | 100 | 91 | 97 | 189 | 17 | 9 |
| Kiko Calero | Bal | mr | 31 | 4.30 | 8 | 4 | 2 | 76 | 0 | 0 | 0 | 104.2 | 102 | 52 | 50 | 49 | 125 | 12 | 9 |
| Shawn Camp | Oak | mr | 30 | 4.50 | 1 | 4 | 0 | 27 | 0 | 0 | 0 | 42.0 | 55 | 22 | 21 | 8 | 28 | 3 | 6 |
| Matt Capps | Sea | mr | 22 | 3.13 | 7 | 7 | 20 | 61 | 0 | 0 | 0 | 77.2 | 77 | 28 | 27 | 13 | 67 | 11 | 10 |
| Chris Capuano* | NYY | sp | 27 | 5.67 | 9 | 18 | 0 | 34 | 34 | 4 | 1 | 208.0 | 266 | 144 | 131 | 50 | 150 | 32 | 27 |
| Chris Carpenter | Tex | sp | 31 | 3.68 | 18 | 7 | 0 | 33 | 32 | 5 | 0 | 222.1 | 227 | 97 | 91 | 49 | 177 | 20 | 18 |
| Hector Carrasco | Min | mr | 36 | 2.82 | 7 | 6 | 2 | 58 | 7 | 0 | 0 | 140.2 | 107 | 51 | 44 | 42 | 111 | 20 | 13 |
| Fabio Castro* | Tor | mr | 21 | 5.14 | 0 | 1 | 1 | 5 | 0 | 0 | 0 | 7.0 | 5 | 4 | 4 | 1 | 5 | 0 | 0 |
| Gustavo Chacin* | Bal | sp | 25 | 6.09 | 3 | 6 | 0 | 18 | 18 | 1 | 0 | 109.1 | 125 | 80 | 74 | 30 | 72 | 24 | 10 |
| Shawn Chacon | Det | sp | 28 | 7.35 | 1 | 2 | 0 | 41 | 2 | 0 | 0 | 101.2 | 129 | 85 | 83 | 52 | 65 | 23 | 9 |
| Bruce Chen* | Cle | mr | 29 | 6.63 | 2 | 9 | 0 | 15 | 15 | 0 | 0 | 73.1 | 102 | 57 | 54 | 33 | 56 | 10 | 4 |
| Vinnie Chulk | Tex | mr | 27 | 4.92 | 4 | 4 | 1 | 46 | 0 | 0 | 0 | 71.1 | 82 | 46 | 39 | 29 | 61 | 7 | 2 |
| Brandon Claussen* | LAA | sp | 27 | 5.51 | 5 | 4 | 0 | 16 | 16 | 0 | 0 | 85.0 | 108 | 54 | 52 | 34 | 66 | 10 | 4 |
| Bartolo Colon | Sea | sp | 33 | 4.36 | 5 | 6 | 0 | 14 | 14 | 4 | 1 | 88.2 | 99 | 48 | 43 | 15 | 54 | 18 | 6 |
| Clay Condrey | Bos | mr | 30 | 2.00 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 9.0 | 9 | 2 | 2 | 0 | 3 | 2 | 2 |
| Tim Corcoran | Tex | sp | 28 | 3.50 | 15 | 6 | 0 | 26 | 26 | 3 | 0 | 159.1 | 143 | 72 | 62 | 82 | 105 | 17 | 24 |
| Francisco Cordero | Tex | cl | 31 | 4.86 | 3 | 8 | 37 | 74 | 0 | 0 | 0 | 83.1 | 90 | 46 | 45 | 39 | 69 | 10 | 4 |
| Lance Cormier | Oak | mr | 25 | 7.63 | 2 | 6 | 0 | 18 | 11 | 0 | 0 | 72.0 | 105 | 62 | 61 | 28 | 49 | 13 | 12 |
| Manuel Corpas | Mtl | mr | 23 | 5.60 | 2 | 0 | 0 | 22 | 0 | 0 | 0 | 35.1 | 42 | 24 | 22 | 8 | 30 | 3 | 4 |
| Juan Cruz | Min | mr | 27 | 3.44 | 12 | 5 | 0 | 23 | 23 | 0 | 0 | 138.2 | 125 | 57 | 53 | 58 | 126 | 10 | 11 |
| Jason Davis | KCR | mr | 26 | 2.31 | 0 | 0 | 1 | 8 | 0 | 0 | 0 | 11.2 | 7 | 3 | 3 | 1 | 7 | 2 | 1 |
| Zach Day | Bal | sp | 28 | 10.43 | 1 | 1 | 0 | 5 | 2 | 0 | 0 | 14.2 | 29 | 17 | 17 | 3 | 4 | 1 | 1 |
| Manny Delcarmen | Cle | mr | 24 | 3.43 | 5 | 3 | 1 | 47 | 0 | 0 | 0 | 63.0 | 61 | 24 | 24 | 18 | 48 | 6 | 8 |
| Ryan Dempster | LAA | cl | 29 | 2.04 | 4 | 8 | 22 | 60 | 0 | 0 | 0 | 66.1 | 45 | 16 | 15 | 35 | 53 | 1 | 1 |
| Joey Devine | Bos | mr | 22 | 8.10 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 3.1 | 2 | 3 | 3 | 3 | 2 | 1 | 1 |
| Scott Downs* | LAA | mr | 30 | 2.83 | 2 | 2 | 2 | 26 | 3 | 0 | 0 | 54.0 | 44 | 23 | 17 | 26 | 44 | 4 | 4 |
| Brandon Duckworth | Cle | sp | 30 | 6.66 | 3 | 1 | 1 | 18 | 4 | 0 | 0 | 48.2 | 60 | 37 | 36 | 24 | 39 | 4 | 4 |
| Zach Duke* | Tor | sp | 23 | 6.64 | 13 | 15 | 0 | 34 | 34 | 0 | 0 | 188.1 | 263 | 149 | 139 | 77 | 112 | 22 | 21 |
| Adam Eaton | LAA | sp | 28 | 5.22 | 6 | 6 | 0 | 16 | 16 | 0 | 0 | 88.0 | 103 | 51 | 51 | 30 | 57 | 18 | 5 |
| Joey Eischen* | Mtl | mr | 36 | 13.50 | 0 | 1 | 0 | 18 | 0 | 0 | 0 | 20.2 | 34 | 32 | 31 | 25 | 25 | 3 | 0 |
| Kelvim Escobar | Min | sp | 30 | 4.10 | 13 | 11 | 0 | 32 | 32 | 4 | 1 | 215.0 | 227 | 102 | 98 | 60 | 167 | 22 | 14 |
| Shawn Estes* | Oak | sp | 33 | 3.60 | 3 | 1 | 0 | 5 | 5 | 0 | 0 | 25.0 | 30 | 13 | 10 | 9 | 11 | 0 | 5 |
| Seth Etherton | ChW | sp | 29 | 13.03 | 0 | 2 | 0 | 3 | 3 | 0 | 0 | 9.2 | 21 | 18 | 14 | 6 | 9 | 3 | 0 |
| Dana Eveland* | Cle | sp | 22 | 7.92 | 1 | 8 | 0 | 11 | 9 | 0 | 0 | 44.1 | 56 | 44 | 39 | 18 | 49 | 12 | 5 |
| Willie Eyre | NYY | mr | 27 | 3.13 | 3 | 1 | 1 | 45 | 0 | 0 | 0 | 100.2 | 89 | 38 | 35 | 28 | 43 | 14 | 9 |
| Kyle Farnsworth | Det | mr | 30 | 3.62 | 6 | 7 | 27 | 49 | 0 | 0 | 0 | 59.2 | 59 | 28 | 24 | 20 | 62 | 7 | 4 |
| Ryan Feierabend* | Det | sp | 20 | 2.42 | 0 | 0 | 0 | 4 | 4 | 0 | 0 | 26.0 | 18 | 8 | 7 | 10 | 20 | 4 | 5 |
| Pedro Feliciano* | NYY | mr | 29 | 4.03 | 7 | 4 | 1 | 48 | 0 | 0 | 0 | 60.1 | 61 | 29 | 27 | 23 | 55 | 4 | 4 |
| Ron Flores* | KCR | mr | 26 | 3.00 | 2 | 1 | 1 | 16 | 0 | 0 | 0 | 30.0 | 21 | 11 | 10 | 10 | 21 | 5 | 1 |
| Casey Fossum* | KCR | sp | 28 | 5.34 | 7 | 10 | 0 | 22 | 22 | 0 | 0 | 123.0 | 139 | 79 | 73 | 40 | 90 | 24 | 7 |
| Keith Foulke | Oak | mr | 33 | 3.18 | 4 | 3 | 4 | 45 | 0 | 0 | 0 | 56.2 | 50 | 21 | 20 | 6 | 43 | 7 | 2 |
| Jeff Francis* | Bos | sp | 25 | 3.59 | 16 | 7 | 0 | 35 | 35 | 7 | 2 | 253.0 | 229 | 109 | 101 | 81 | 150 | 24 | 36 |
| Ryan Franklin | Tex | mr | 33 | 6.07 | 3 | 1 | 0 | 52 | 0 | 0 | 0 | 80.0 | 90 | 55 | 54 | 37 | 34 | 9 | 16 |
| Brian Fuentes* | Bal | cl | 30 | 2.90 | 10 | 5 | 23 | 75 | 0 | 0 | 0 | 99.1 | 86 | 37 | 32 | 46 | 107 | 13 | 7 |
| Aaron Fultz* | Cle | mr | 32 | 4.20 | 4 | 2 | 2 | 44 | 4 | 0 | 0 | 60.0 | 65 | 29 | 28 | 18 | 60 | 5 | 1 |
| Kason Gabbard* | Tor | sp | 24 | 5.35 | 2 | 1 | 0 | 7 | 7 | 1 | 0 | 37.0 | 37 | 23 | 22 | 30 | 16 | 2 | 5 |
| Jon Garland | Mtl | sp | 26 | 5.32 | 8 | 22 | 0 | 34 | 34 | 3 | 0 | 220.0 | 271 | 141 | 130 | 38 | 130 | 29 | 24 |
| Matt Garza | Bal | sp | 22 | 7.88 | 1 | 5 | 0 | 7 | 6 | 0 | 0 | 32.0 | 52 | 37 | 28 | 16 | 24 | 4 | 3 |
| Geoff Geary | LAA | mr | 29 | 3.58 | 6 | 3 | 7 | 62 | 0 | 0 | 0 | 105.2 | 117 | 50 | 42 | 23 | 73 | 5 | 16 |
| Jimmy Gobble* | Cle | mr | 24 | 4.93 | 10 | 2 | 0 | 41 | 10 | 0 | 0 | 107.2 | 111 | 61 | 59 | 44 | 103 | 17 | 8 |
| Enrique Gonzalez | KCR | sp | 23 | 5.20 | 4 | 3 | 0 | 12 | 11 | 0 | 0 | 55.1 | 62 | 39 | 32 | 23 | 30 | 8 | 7 |
| Geremi Gonzalez | Oak | mr | 31 | 10.13 | 0 | 5 | 0 | 19 | 4 | 0 | 0 | 50.2 | 85 | 60 | 57 | 20 | 45 | 15 | 1 |
| Tom Gordon | Bal | cl | 38 | 3.52 | 3 | 6 | 9 | 64 | 0 | 0 | 0 | 94.2 | 91 | 41 | 37 | 28 | 93 | 14 | 7 |
| Tom Gorzelanny* | Sea | sp | 23 | 4.50 | 7 | 3 | 0 | 15 | 15 | 0 | 0 | 94.0 | 75 | 50 | 47 | 48 | 72 | 8 | 9 |
| John Grabow* | KCR | mr | 27 | 3.94 | 2 | 3 | 2 | 41 | 0 | 0 | 0 | 64.0 | 61 | 31 | 28 | 26 | 72 | 5 | 4 |
| Zack Greinke | Bos | mr | 22 | 5.79 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 4.2 | 4 | 3 | 3 | 1 | 1 | 1 | 0 |
| Eddie Guardado* | Mtl | cl | 35 | 8.20 | 1 | 5 | 0 | 43 | 0 | 0 | 0 | 52.2 | 75 | 48 | 48 | 25 | 60 | 19 | 1 |
| Charlie Haeger | Cle | mr | 22 | 3.10 | 6 | 0 | 0 | 13 | 4 | 0 | 0 | 49.1 | 33 | 20 | 17 | 44 | 45 | 1 | 4 |
| Jason Hammel | ChW | sp | 23 | 7.62 | 1 | 5 | 0 | 10 | 10 | 0 | 0 | 39.0 | 60 | 38 | 33 | 30 | 28 | 7 | 3 |
| Chris Hammond* | Tor | mr | 40 | 5.14 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 7.0 | 7 | 4 | 4 | 1 | 5 | 2 | 1 |
| Josh Hancock | NYY | mr | 28 | 3.66 | 3 | 1 | 1 | 37 | 0 | 0 | 0 | 71.1 | 69 | 33 | 29 | 23 | 40 | 7 | 9 |
| Aaron Harang | Was | sp | 28 | 6.09 | 5 | 10 | 0 | 18 | 18 | 2 | 1 | 105.0 | 144 | 77 | 71 | 24 | 105 | 18 | 13 |
| Travis Harper | LAA | mr | 30 | 10.13 | 0 | 2 | 0 | 18 | 0 | 0 | 0 | 26.2 | 58 | 31 | 30 | 14 | 21 | 6 | 4 |
| Chad Harville | Det | mr | 29 | 4.17 | 0 | 0 | 0 | 17 | 0 | 0 | 0 | 36.2 | 34 | 17 | 17 | 27 | 26 | 5 | 6 |
| LaTroy Hawkins | Cle | mr | 33 | 3.48 | 4 | 6 | 2 | 58 | 0 | 0 | 0 | 64.2 | 80 | 28 | 25 | 18 | 34 | 4 | 4 |
| Aaron Heilman | Oak | mr | 27 | 4.08 | 4 | 3 | 0 | 33 | 0 | 0 | 0 | 46.1 | 41 | 22 | 21 | 21 | 42 | 4 | 3 |
| Rick Helling | Bos | mr | 35 | 5.76 | 1 | 2 | 0 | 15 | 3 | 0 | 0 | 29.2 | 26 | 20 | 19 | 7 | 28 | 10 | 0 |
| Mark Hendrickson* | LAA | sp | 32 | 4.42 | 12 | 8 | 0 | 38 | 27 | 0 | 0 | 193.1 | 208 | 100 | 95 | 71 | 129 | 16 | 24 |
| Sean Henn* | Tex | mr | 25 | 5.40 | 0 | 1 | 0 | 2 | 1 | 0 | 0 | 6.2 | 8 | 5 | 4 | 3 | 5 | 0 | 1 |
| Clay Hensley | Bal | sp | 26 | 4.85 | 15 | 12 | 0 | 34 | 34 | 5 | 2 | 207.2 | 225 | 119 | 112 | 81 | 130 | 19 | 36 |
| Felix Hernandez | Min | sp | 20 | 3.43 | 15 | 7 | 0 | 32 | 32 | 2 | 1 | 217.2 | 209 | 89 | 83 | 55 | 189 | 21 | 18 |
| Livan Hernandez | Was | sp | 31 | 4.95 | 15 | 7 | 0 | 34 | 34 | 1 | 0 | 218.0 | 249 | 133 | 120 | 65 | 104 | 30 | 17 |
| Orlando Hernandez | Sea | sp | 36 | 4.69 | 7 | 16 | 0 | 31 | 31 | 0 | 0 | 186.0 | 182 | 106 | 97 | 82 | 183 | 33 | 14 |
| Roberto Hernandez | Tor | mr | 41 | 5.22 | 3 | 3 | 3 | 64 | 0 | 0 | 0 | 110.1 | 120 | 68 | 64 | 51 | 83 | 15 | 8 |
| Runelvys Hernandez | ChW | sp | 28 | 6.58 | 7 | 12 | 0 | 30 | 30 | 0 | 0 | 135.1 | 201 | 118 | 99 | 59 | 57 | 32 | 23 |
| Jason Hirsh | Tex | sp | 24 | 7.60 | 3 | 9 | 0 | 19 | 19 | 0 | 0 | 98.1 | 103 | 90 | 83 | 56 | 65 | 21 | 6 |
| J.P. Howell* | Bos | sp | 23 | 3.55 | 5 | 2 | 0 | 11 | 11 | 0 | 0 | 58.1 | 59 | 23 | 23 | 19 | 56 | 3 | 7 |
| Tim Hudson | Det | sp | 30 | 5.64 | 9 | 17 | 0 | 30 | 30 | 3 | 0 | 188.1 | 225 | 125 | 118 | 61 | 124 | 24 | 18 |
| Jason Isringhausen | Bos | cl | 33 | 3.34 | 6 | 4 | 4 | 53 | 0 | 0 | 0 | 62.0 | 35 | 23 | 23 | 31 | 60 | 6 | 2 |
| Edwin Jackson | Min | mr | 22 | 4.41 | 1 | 0 | 0 | 16 | 3 | 0 | 0 | 49.0 | 45 | 25 | 24 | 39 | 40 | 3 | 6 |
| Zach Jackson* | Tex | sp | 23 | 7.86 | 1 | 4 | 0 | 8 | 8 | 0 | 0 | 34.1 | 37 | 32 | 30 | 21 | 15 | 6 | 3 |
| Chuck James* | Bos | sp | 24 | 4.86 | 5 | 6 | 0 | 22 | 21 | 0 | 0 | 122.1 | 116 | 71 | 66 | 53 | 97 | 19 | 8 |
| Bobby Jenks | KCR | cl | 25 | 2.29 | 9 | 2 | 29 | 57 | 0 | 0 | 0 | 78.2 | 79 | 22 | 20 | 21 | 96 | 4 | 13 |
| Tyler Johnson* | Sea | mr | 25 | 5.86 | 2 | 5 | 7 | 46 | 0 | 0 | 0 | 58.1 | 55 | 45 | 38 | 56 | 59 | 7 | 7 |
| Todd Jones | Mtl | cl | 38 | 1.88 | 3 | 5 | 26 | 53 | 0 | 0 | 0 | 67.0 | 53 | 14 | 14 | 13 | 28 | 2 | 15 |
| Scott Kazmir* | Bos | sp | 22 | 3.72 | 16 | 6 | 0 | 27 | 27 | 1 | 0 | 167.0 | 156 | 76 | 69 | 52 | 195 | 13 | 12 |
| Randy Keisler* | Mtl | mr | 30 | 5.23 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 10.1 | 12 | 7 | 6 | 3 | 5 | 2 | 5 |
| Joe Kennedy* | Min | mr | 27 | 1.38 | 4 | 0 | 0 | 34 | 0 | 0 | 0 | 52.1 | 42 | 11 | 8 | 10 | 50 | 1 | 3 |
| Logan Kensing | Was | mr | 23 | 5.73 | 0 | 0 | 0 | 42 | 0 | 0 | 0 | 75.1 | 72 | 48 | 48 | 42 | 86 | 15 | 4 |
| Bobby Keppel | Bal | sp | 24 | 5.61 | 6 | 4 | 0 | 14 | 14 | 1 | 0 | 78.2 | 97 | 49 | 49 | 23 | 47 | 13 | 13 |
| Byung-Hyun Kim | Bos | sp | 27 | 4.24 | 13 | 6 | 0 | 30 | 30 | 0 | 0 | 178.1 | 209 | 87 | 84 | 88 | 137 | 18 | 34 |
| Dan Kolb | ChW | mr | 31 | 5.17 | 0 | 0 | 1 | 22 | 0 | 0 | 0 | 38.1 | 55 | 22 | 22 | 10 | 19 | 5 | 5 |
| Hong-Chih Kuo* | Bos | mr | 24 | 5.88 | 3 | 3 | 1 | 30 | 5 | 0 | 0 | 64.1 | 70 | 43 | 42 | 39 | 88 | 6 | 6 |
| John Lackey | Bal | sp | 27 | 3.96 | 14 | 14 | 0 | 38 | 38 | 1 | 1 | 265.2 | 271 | 121 | 117 | 79 | 216 | 22 | 13 |
| Brandon League | Min | mr | 23 | 2.08 | 4 | 0 | 8 | 30 | 0 | 0 | 0 | 78.0 | 74 | 22 | 18 | 9 | 56 | 3 | 7 |
| Brad Lidge | ChW | cl | 29 | 4.52 | 2 | 9 | 33 | 62 | 0 | 0 | 0 | 71.2 | 75 | 37 | 36 | 39 | 106 | 11 | 6 |
| Francisco Liriano* | Min | sp | 22 | 3.38 | 14 | 4 | 0 | 23 | 23 | 3 | 3 | 151.2 | 127 | 65 | 57 | 35 | 182 | 11 | 20 |
| Esteban Loaiza | LAA | sp | 34 | 5.06 | 7 | 12 | 0 | 26 | 26 | 1 | 1 | 151.1 | 187 | 97 | 85 | 31 | 113 | 15 | 10 |
| Kameron Loe | NYY | sp | 24 | 7.31 | 1 | 3 | 0 | 4 | 4 | 0 | 0 | 16.0 | 23 | 13 | 13 | 5 | 5 | 3 | 2 |
| Boone Logan* | ChW | mr | 21 | 5.94 | 1 | 0 | 0 | 9 | 0 | 0 | 0 | 16.2 | 17 | 12 | 11 | 9 | 16 | 1 | 4 |
| Javier Lopez* | Tex | mr | 28 | 13.50 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1.1 | 3 | 2 | 2 | 1 | 2 | 0 | 0 |
| Rodrigo Lopez | NYY | sp | 30 | 4.67 | 11 | 10 | 0 | 30 | 30 | 3 | 1 | 181.1 | 203 | 112 | 94 | 64 | 130 | 23 | 15 |
| Mark Lowe | Bos | mr | 23 | 4.19 | 1 | 6 | 4 | 20 | 0 | 0 | 0 | 38.2 | 44 | 18 | 18 | 17 | 40 | 2 | 7 |
| Ruddy Lugo | Was | mr | 26 | 3.30 | 4 | 3 | 3 | 62 | 0 | 0 | 0 | 90.0 | 83 | 39 | 33 | 38 | 56 | 7 | 10 |
| Ryan Madson | NYY | mr | 25 | 9.09 | 0 | 0 | 2 | 33 | 0 | 0 | 0 | 63.1 | 106 | 67 | 64 | 22 | 41 | 10 | 7 |
| Carlos Marmol | Bal | sp | 23 | 6.55 | 4 | 4 | 0 | 15 | 14 | 0 | 0 | 78.1 | 78 | 63 | 57 | 67 | 56 | 17 | 2 |
| Mike Maroth* | Tor | sp | 28 | 4.46 | 9 | 6 | 0 | 21 | 20 | 0 | 0 | 117.0 | 151 | 70 | 58 | 30 | 49 | 15 | 27 |
| Damaso Marte* | Was | mr | 31 | 3.08 | 5 | 3 | 2 | 59 | 0 | 0 | 0 | 61.1 | 44 | 23 | 21 | 38 | 66 | 6 | 8 |
| Carlos Martinez | Mtl | mr | 24 | 3.18 | 1 | 0 | 0 | 22 | 0 | 0 | 0 | 34.0 | 28 | 13 | 12 | 13 | 33 | 1 | 2 |
| Tom Mastny | Tex | cl | 25 | 9.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 |
| Juan Mateo | KCR | sp | 23 | 3.63 | 1 | 3 | 0 | 4 | 4 | 0 | 0 | 22.1 | 27 | 10 | 9 | 10 | 24 | 2 | 2 |
| Dustin McGowan | Cle | mr | 24 | 5.29 | 1 | 3 | 0 | 17 | 7 | 0 | 0 | 49.1 | 67 | 30 | 29 | 41 | 40 | 2 | 4 |
| Marty McLeary | NYY | mr | 31 | 0.00 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 6.1 | 1 | 0 | 0 | 3 | 2 | 0 | 1 |
| Brian Meadows | Bal | mr | 30 | 5.32 | 1 | 0 | 2 | 13 | 0 | 0 | 0 | 23.2 | 30 | 15 | 14 | 3 | 18 | 7 | 3 |
| Gil Meche |   | sp | 27 | 6.05 | 14 | 14 | 0 | 32 | 32 | 1 | 0 | 172.2 | 187 | 127 | 116 | 69 | 148 | 26 | 21 |
| Brandon Medders | Mtl | mr | 26 | 3.61 | 6 | 2 | 1 | 68 | 0 | 0 | 0 | 124.2 | 128 | 56 | 50 | 52 | 75 | 9 | 16 |
| Jose Mesa | Bal | mr | 40 | 4.16 | 3 | 4 | 3 | 64 | 0 | 0 | 0 | 106.0 | 113 | 60 | 49 | 42 | 57 | 10 | 16 |
| Dan Miceli | Tor | mr | 35 | 2.66 | 1 | 0 | 3 | 17 | 0 | 0 | 0 | 23.2 | 18 | 7 | 7 | 9 | 21 | 3 | 0 |
| Trever Miller* | Det | mr | 33 | 3.05 | 1 | 3 | 2 | 45 | 0 | 0 | 0 | 62.0 | 57 | 21 | 21 | 12 | 75 | 6 | 2 |
| Eric Milton* | Cle | sp | 30 | 6.09 | 8 | 14 | 0 | 30 | 30 | 1 | 0 | 174.1 | 211 | 127 | 118 | 44 | 115 | 31 | 12 |
| Zach Miner | Det | sp | 24 | 4.18 | 5 | 5 | 0 | 13 | 13 | 1 | 0 | 79.2 | 91 | 40 | 37 | 27 | 54 | 9 | 5 |
| Brian Moehler | Sea | sp | 34 | 4.58 | 3 | 2 | 0 | 6 | 6 | 0 | 0 | 35.1 | 47 | 20 | 18 | 9 | 16 | 3 | 6 |
| Matt Morris | Mtl | sp | 31 | 5.20 | 5 | 9 | 0 | 18 | 18 | 1 | 0 | 110.2 | 137 | 81 | 64 | 36 | 59 | 13 | 9 |
| Jamie Moyer* | Tor | sp | 43 | 5.76 | 9 | 12 | 0 | 33 | 33 | 3 | 0 | 193.2 | 234 | 135 | 124 | 55 | 109 | 27 | 17 |
| Edward Mujica | Cle | mr | 22 | 5.60 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 17.2 | 29 | 16 | 11 | 0 | 12 | 3 | 2 |
| Mark Mulder* | Was | sp | 28 | 13.50 | 0 | 1 | 0 | 2 | 2 | 0 | 0 | 7.1 | 12 | 11 | 11 | 8 | 3 | 1 | 1 |
| Scott Munter | NYY | mr | 26 | 6.62 | 0 | 0 | 0 | 12 | 0 | 0 | 0 | 17.2 | 24 | 13 | 13 | 5 | 7 | 2 | 3 |
| Brett Myers | Oak | sp | 25 | 3.63 | 12 | 9 | 0 | 30 | 30 | 3 | 1 | 208.1 | 209 | 95 | 84 | 70 | 190 | 21 | 29 |
| Chris Narveson* | Min | mr | 24 | 4.33 | 2 | 1 | 0 | 5 | 5 | 0 | 0 | 27.0 | 18 | 13 | 13 | 15 | 34 | 1 | 0 |
| Joe Nathan | Was | cl | 31 | 0.52 | 11 | 0 | 23 | 64 | 0 | 0 | 0 | 104.0 | 40 | 7 | 6 | 14 | 141 | 4 | 5 |
| Joe Nelson | ChW | mr | 31 | 2.61 | 4 | 1 | 3 | 27 | 0 | 0 | 0 | 38.0 | 29 | 11 | 11 | 9 | 34 | 5 | 5 |
| Fernando Nieve | Bos | mr | 23 | 5.27 | 8 | 5 | 0 | 26 | 19 | 1 | 0 | 124.2 | 129 | 74 | 73 | 54 | 77 | 29 | 16 |
| Roberto Novoa | Sea | mr | 26 | 4.74 | 5 | 1 | 0 | 65 | 0 | 0 | 0 | 98.2 | 97 | 56 | 52 | 37 | 72 | 19 | 18 |
| Mike O'Connor* | KCR | sp | 25 | 6.47 | 4 | 6 | 0 | 16 | 16 | 0 | 0 | 79.1 | 92 | 58 | 57 | 34 | 46 | 10 | 5 |
| Ryan O'Malley* | Was | sp | 26 | 4.24 | 1 | 5 | 0 | 7 | 7 | 0 | 0 | 34.0 | 31 | 21 | 16 | 28 | 7 | 0 | 2 |
| Darren Oliver* |   | mr | 35 | 3.83 | 6 | 4 | 0 | 50 | 0 | 0 | 0 | 91.2 | 76 | 44 | 39 | 36 | 71 | 10 | 10 |
| Ramon Ortiz | NYY | sp | 33 | 6.40 | 7 | 15 | 0 | 29 | 29 | 0 | 0 | 156.0 | 226 | 121 | 111 | 44 | 87 | 27 | 17 |
| Russ Ortiz | Tor | mr | 32 | 7.87 | 2 | 6 | 0 | 12 | 12 | 0 | 0 | 50.1 | 73 | 45 | 44 | 27 | 43 | 8 | 4 |
| Vicente Padilla | KCR | sp | 28 | 3.91 | 10 | 8 | 0 | 31 | 31 | 2 | 2 | 184.0 | 171 | 85 | 80 | 61 | 148 | 19 | 15 |
| Jonathan Papelbon | Min | cl | 25 | 1.53 | 9 | 4 | 41 | 63 | 0 | 0 | 0 | 82.1 | 42 | 14 | 14 | 14 | 74 | 2 | 3 |
| Chan Ho Park | ChW | sp | 33 | 3.43 | 13 | 4 | 0 | 22 | 22 | 5 | 1 | 157.1 | 160 | 72 | 60 | 40 | 113 | 17 | 17 |
| Jake Peavy | ChW | sp | 25 | 4.59 | 14 | 10 | 0 | 31 | 31 | 4 | 2 | 206.0 | 219 | 108 | 105 | 56 | 229 | 29 | 14 |
| Tony Pena | Oak | mr | 24 | 3.82 | 2 | 3 | 1 | 27 | 0 | 0 | 0 | 37.2 | 36 | 19 | 16 | 9 | 25 | 2 | 5 |
| Joel Peralta | Tex | mr | 30 | 3.36 | 3 | 4 | 1 | 71 | 0 | 0 | 0 | 96.1 | 87 | 43 | 36 | 41 | 65 | 8 | 7 |
| Odalis Perez* | Min | sp | 29 | 4.79 | 9 | 11 | 0 | 30 | 30 | 2 | 0 | 163.1 | 192 | 99 | 87 | 35 | 107 | 21 | 4 |
| Oliver Perez* | LAA | sp | 24 | 5.63 | 4 | 7 | 0 | 15 | 15 | 0 | 0 | 78.1 | 88 | 58 | 49 | 61 | 65 | 14 | 9 |
| Joel Pineiro | Sea | sp | 27 | 6.65 | 2 | 5 | 1 | 38 | 11 | 0 | 0 | 115.0 | 138 | 95 | 85 | 37 | 55 | 23 | 9 |
| Mark Prior | KCR | sp | 25 | 1.59 | 1 | 0 | 0 | 2 | 2 | 0 | 0 | 11.1 | 6 | 2 | 2 | 7 | 5 | 0 | 1 |
| Scott Proctor | NYY | mr | 29 | 4.24 | 4 | 9 | 4 | 65 | 0 | 0 | 0 | 97.2 | 82 | 53 | 46 | 23 | 76 | 17 | 6 |
| Brad Radke | Was | sp | 33 | 6.34 | 3 | 4 | 0 | 13 | 13 | 1 | 0 | 65.1 | 102 | 48 | 46 | 17 | 35 | 12 | 8 |
| Horacio Ramirez* | Tex | sp | 26 | 4.92 | 9 | 8 | 0 | 23 | 23 | 1 | 0 | 139.0 | 162 | 81 | 76 | 58 | 70 | 16 | 15 |
| Chris Ray | Cle | cl | 24 | 2.26 | 1 | 4 | 29 | 49 | 0 | 0 | 0 | 51.2 | 31 | 13 | 13 | 20 | 38 | 4 | 1 |
| Mark Redman* | Mtl | sp | 32 | 5.49 | 6 | 15 | 0 | 31 | 31 | 1 | 0 | 177.0 | 211 | 116 | 108 | 60 | 76 | 21 | 21 |
| Chris Resop | Cle | mr | 23 | 4.56 | 0 | 0 | 1 | 37 | 0 | 0 | 0 | 47.1 | 66 | 25 | 24 | 25 | 16 | 2 | 13 |
| Anthony Reyes | KCR | sp | 24 | 8.94 | 1 | 5 | 0 | 12 | 12 | 0 | 0 | 47.1 | 65 | 48 | 47 | 20 | 34 | 16 | 4 |
| David Riske | ChW | mr | 29 | 7.20 | 0 | 4 | 0 | 17 | 0 | 0 | 0 | 20.0 | 25 | 18 | 16 | 12 | 15 | 3 | 2 |
| Mariano Rivera | Tor | cl | 36 | 2.49 | 4 | 2 | 7 | 68 | 0 | 0 | 0 | 104.2 | 104 | 34 | 29 | 10 | 74 | 5 | 15 |
| Francisco Rodriguez | Tor | cl | 24 | 2.79 | 8 | 10 | 9 | 67 | 0 | 0 | 0 | 109.2 | 90 | 36 | 34 | 32 | 140 | 11 | 6 |
| Kenny Rogers* | LAA | sp | 41 | 3.38 | 19 | 10 | 0 | 34 | 34 | 3 | 0 | 237.0 | 221 | 94 | 89 | 63 | 115 | 21 | 31 |
| Glendon Rusch* | LAA | mr | 31 | 8.49 | 1 | 0 | 1 | 21 | 0 | 0 | 0 | 35.0 | 58 | 35 | 33 | 15 | 32 | 10 | 6 |
| B.J. Ryan* | Was | cl | 30 | 0.70 | 10 | 1 | 24 | 57 | 0 | 0 | 0 | 90.0 | 30 | 8 | 7 | 29 | 108 | 2 | 9 |
| Kirk Saarloos | Bal | mr | 27 | 4.79 | 4 | 10 | 0 | 29 | 19 | 2 | 0 | 139.0 | 150 | 84 | 74 | 41 | 68 | 22 | 21 |
| C.C. Sabathia* |   | sp | 25 | 3.57 | 16 | 11 | 0 | 32 | 32 | 3 | 1 | 214.1 | 229 | 101 | 85 | 42 | 208 | 14 | 19 |
| Juan Salas | Oak | mr | 27 | 40.50 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 1.1 | 6 | 6 | 6 | 0 | 1 | 1 | 1 |
| Chris Sampson | NYY | mr | 28 | 1.31 | 2 | 0 | 0 | 3 | 3 | 0 | 0 | 20.2 | 17 | 3 | 3 | 2 | 7 | 2 | 2 |
| Anibal Sanchez | Was | sp | 22 | 3.52 | 11 | 6 | 0 | 21 | 21 | 1 | 0 | 135.2 | 108 | 57 | 53 | 61 | 70 | 10 | 16 |
| Duaner Sanchez | Mtl | mr | 26 | 4.67 | 2 | 0 | 0 | 35 | 0 | 0 | 0 | 69.1 | 64 | 39 | 36 | 33 | 62 | 6 | 10 |
| Johan Santana* | Sea | sp | 27 | 3.29 | 17 | 14 | 0 | 33 | 33 | 6 | 0 | 246.1 | 225 | 100 | 90 | 45 | 260 | 23 | 21 |
| Scott Sauerbeck* | ChW | mr | 34 | 7.41 | 3 | 1 | 0 | 14 | 0 | 0 | 0 | 17.0 | 18 | 16 | 14 | 13 | 14 | 2 | 2 |
| Joe Saunders* | Cle | sp | 25 | 2.70 | 7 | 3 | 0 | 17 | 17 | 2 | 0 | 116.2 | 115 | 45 | 35 | 36 | 66 | 7 | 19 |
| Scott Schoeneweis* | Tex | mr | 32 | 3.54 | 4 | 2 | 5 | 60 | 0 | 0 | 0 | 76.1 | 68 | 30 | 30 | 32 | 37 | 9 | 15 |
| Chris Schroder | Tex | mr | 27 | 5.40 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 5.0 | 3 | 3 | 3 | 5 | 6 | 0 | 0 |
| Rudy Seanez | Det | mr | 37 | 6.45 | 2 | 0 | 0 | 14 | 0 | 0 | 0 | 22.1 | 26 | 16 | 16 | 12 | 23 | 4 | 1 |
| Bobby Seay* | LAA | mr | 28 | 11.57 | 0 | 0 | 1 | 3 | 0 | 0 | 0 | 2.1 | 4 | 3 | 3 | 4 | 2 | 1 | 0 |
| Ben Sheets | Oak | sp | 27 | 3.69 | 7 | 10 | 0 | 22 | 22 | 7 | 1 | 165.2 | 163 | 73 | 68 | 19 | 174 | 18 | 12 |
| George Sherrill* | KCR | mr | 29 | 3.48 | 6 | 5 | 1 | 62 | 0 | 0 | 0 | 62.0 | 53 | 26 | 24 | 28 | 64 | 0 | 4 |
| Matt Smith* | Cle | mr | 27 | 1.08 | 1 | 0 | 0 | 20 | 0 | 0 | 0 | 25.0 | 15 | 5 | 3 | 10 | 24 | 1 | 1 |
| Kyle Snyder | Tex | sp | 28 | 5.90 | 3 | 5 | 0 | 37 | 10 | 0 | 0 | 100.2 | 141 | 71 | 66 | 26 | 93 | 16 | 8 |
| Rafael Soriano | Min | mr | 26 | 3.23 | 8 | 7 | 7 | 47 | 0 | 0 | 0 | 78.0 | 59 | 30 | 28 | 29 | 77 | 9 | 5 |
| Jeremy Sowers* | Det | sp | 23 | 3.98 | 4 | 10 | 0 | 17 | 17 | 3 | 0 | 110.2 | 105 | 55 | 49 | 26 | 40 | 14 | 8 |
| Brian Stokes | Oak | sp | 26 | 8.62 | 0 | 9 | 0 | 12 | 12 | 0 | 0 | 62.2 | 92 | 68 | 60 | 29 | 41 | 6 | 6 |
| Huston Street | NYY | cl | 22 | 2.49 | 3 | 7 | 29 | 56 | 0 | 0 | 0 | 68.2 | 57 | 19 | 19 | 16 | 67 | 4 | 2 |
| Jeff Suppan | Was | sp | 31 | 5.12 | 12 | 13 | 0 | 33 | 33 | 0 | 0 | 188.0 | 217 | 129 | 107 | 73 | 107 | 23 | 28 |
| Taylor Tankersley* | Det | mr | 23 | 5.70 | 0 | 2 | 3 | 28 | 0 | 0 | 0 | 42.2 | 39 | 28 | 27 | 24 | 51 | 4 | 5 |
| Jack Taschner* | NYY | mr | 28 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| Ty Taubenheim | ChW | sp | 23 | 4.80 | 0 | 0 | 0 | 19 | 0 | 0 | 0 | 30.0 | 36 | 19 | 16 | 17 | 23 | 5 | 3 |
| Mike Timlin | Was | mr | 40 | 2.79 | 4 | 1 | 0 | 25 | 0 | 0 | 0 | 29.0 | 35 | 10 | 9 | 3 | 13 | 3 | 4 |
| Brett Tomko | NYY | mr | 33 | 4.45 | 7 | 11 | 0 | 23 | 23 | 1 | 0 | 151.2 | 169 | 85 | 75 | 28 | 99 | 25 | 5 |
| Salomon Torres | LAA | mr | 34 | 2.45 | 5 | 2 | 11 | 65 | 0 | 0 | 0 | 95.2 | 98 | 32 | 26 | 31 | 81 | 3 | 20 |
| Josh Towers | Tex | sp | 29 | 8.70 | 1 | 10 | 0 | 12 | 12 | 0 | 0 | 50.2 | 100 | 59 | 49 | 13 | 17 | 12 | 8 |
| Steve Trachsel | LAA | sp | 35 | 5.46 | 9 | 13 | 0 | 25 | 25 | 0 | 0 | 146.2 | 166 | 99 | 89 | 75 | 71 | 27 | 16 |
| Jose Veras | Oak | mr | 25 | 4.76 | 0 | 0 | 0 | 14 | 0 | 0 | 0 | 17.0 | 19 | 11 | 9 | 12 | 16 | 3 | 1 |
| Justin Verlander | Cle | sp | 23 | 4.02 | 12 | 16 | 0 | 32 | 32 | 4 | 2 | 206.0 | 215 | 102 | 92 | 75 | 141 | 20 | 29 |
| Ron Villone* | LAA | mr | 36 | 3.35 | 3 | 2 | 9 | 60 | 0 | 0 | 0 | 83.1 | 86 | 34 | 31 | 34 | 78 | 7 | 5 |
| Luis Vizcaino | Bos | mr | 31 | 3.30 | 5 | 4 | 7 | 60 | 0 | 0 | 0 | 76.1 | 69 | 31 | 28 | 21 | 76 | 11 | 7 |
| Ryan Vogelsong | Was | mr | 28 | 5.65 | 0 | 0 | 0 | 20 | 0 | 0 | 0 | 43.0 | 53 | 28 | 27 | 20 | 35 | 7 | 3 |
| Edinson Volquez | Mtl | sp | 22 | 6.14 | 4 | 5 | 0 | 11 | 11 | 0 | 0 | 58.2 | 76 | 41 | 40 | 24 | 20 | 9 | 5 |
| Billy Wagner* | Bos | cl | 34 | 3.56 | 5 | 8 | 27 | 66 | 0 | 0 | 0 | 83.1 | 82 | 34 | 33 | 32 | 118 | 6 | 8 |
| Ryan Wagner | Oak | mr | 23 | 4.42 | 0 | 0 | 0 | 15 | 0 | 0 | 0 | 18.1 | 21 | 9 | 9 | 5 | 9 | 0 | 2 |
| Tim Wakefield | Sea | sp | 39 | 4.19 | 11 | 10 | 0 | 27 | 27 | 7 | 0 | 199.2 | 181 | 98 | 93 | 61 | 109 | 32 | 11 |
| John Wasdin | Oak | sp | 33 | 5.44 | 1 | 6 | 0 | 8 | 8 | 0 | 0 | 46.1 | 45 | 32 | 28 | 18 | 21 | 8 | 3 |
| Jarrod Washburn* | Det | sp | 31 | 5.25 | 11 | 10 | 0 | 31 | 31 | 1 | 0 | 185.0 | 213 | 115 | 108 | 51 | 107 | 17 | 13 |
| David Weathers | Det | mr | 36 | 4.02 | 10 | 6 | 1 | 50 | 0 | 0 | 0 | 65.0 | 61 | 33 | 29 | 33 | 47 | 7 | 5 |
| Brandon Webb | Det | sp | 27 | 3.32 | 18 | 9 | 0 | 33 | 33 | 6 | 1 | 244.1 | 221 | 95 | 90 | 54 | 180 | 18 | 23 |
| David Wells* | Bal | sp | 43 | 6.04 | 6 | 8 | 0 | 17 | 17 | 3 | 0 | 107.1 | 160 | 77 | 72 | 20 | 51 | 17 | 20 |
| Kip Wells | Mtl | sp | 29 | 7.64 | 2 | 13 | 0 | 16 | 16 | 0 | 0 | 88.1 | 106 | 80 | 75 | 55 | 28 | 15 | 7 |
| Jake Westbrook | Tex | sp | 28 | 4.12 | 13 | 13 | 0 | 31 | 31 | 6 | 3 | 222.2 | 232 | 115 | 102 | 51 | 115 | 25 | 22 |
| Dave Williams* | Tor | sp | 27 | 9.71 | 1 | 13 | 0 | 24 | 24 | 0 | 0 | 80.2 | 141 | 93 | 87 | 32 | 32 | 17 | 9 |
| Jerome Williams | Mtl | mr | 24 | 12.13 | 1 | 9 | 0 | 12 | 12 | 0 | 0 | 46.0 | 78 | 63 | 62 | 45 | 22 | 11 | 6 |
| Dontrelle Willis* | Was | sp | 24 | 3.77 | 15 | 12 | 0 | 34 | 34 | 5 | 3 | 217.0 | 228 | 106 | 91 | 80 | 169 | 13 | 31 |
| C.J. Wilson* | Min | mr | 25 | 7.14 | 1 | 1 | 0 | 22 | 0 | 0 | 0 | 29.0 | 33 | 24 | 23 | 12 | 38 | 7 | 3 |
| Matt Wise | ChW | mr | 30 | 5.21 | 2 | 1 | 1 | 31 | 0 | 0 | 0 | 46.2 | 56 | 28 | 27 | 14 | 29 | 6 | 6 |
| Kerry Wood | Mtl | sp | 29 | 7.79 | 0 | 7 | 0 | 9 | 9 | 0 | 0 | 52.0 | 53 | 46 | 45 | 38 | 30 | 14 | 4 |
| Mike Wood | Mtl | mr | 26 | 5.69 | 7 | 17 | 0 | 31 | 31 | 3 | 1 | 175.2 | 249 | 124 | 111 | 42 | 75 | 24 | 15 |
| Jaret Wright | Det | sp | 30 | 4.92 | 7 | 10 | 0 | 29 | 29 | 1 | 0 | 164.2 | 179 | 93 | 90 | 77 | 94 | 9 | 16 |
| Tyler Yates | Tor | mr | 28 | 6.03 | 1 | 2 | 5 | 63 | 0 | 0 | 0 | 88.0 | 101 | 64 | 59 | 49 | 84 | 17 | 9 |
| Shane Youman* | Min | sp | 26 | 2.12 | 5 | 1 | 0 | 7 | 7 | 0 | 0 | 46.2 | 22 | 12 | 11 | 28 | 16 | 3 | 7 |
| Victor Zambrano | Det | sp | 30 | 6.35 | 1 | 2 | 0 | 3 | 3 | 0 | 0 | 11.1 | 15 | 10 | 8 | 9 | 9 | 1 | 3 |
| Barry Zito* | ChW | sp | 28 | 3.50 | 13 | 9 | 0 | 34 | 34 | 3 | 2 | 236.1 | 203 | 95 | 92 | 93 | 170 | 23 | 31 |
| Joel Zumaya | KCR | mr | 21 | 3.07 | 9 | 4 | 7 | 66 | 0 | 0 | 0 | 120.0 | 87 | 50 | 41 | 60 | 137 | 14 | 5 |
| Secondary |
| Name | Team | P | Age | SB | CS | IW | HBP | WP | BK | SH | SF | H/9 | BB/9 | R/9 | K/9 | HR/9 | K/BB | WHIP |
| Jeremy Accardo | ChW | mr | 24 | 0 | 1 | 3 | 1 | 6 | 1 | 0 | 3 | 10.6 | 2.5 | 13.3 | 7.6 | 1.1 | 3.1 | 1.46 |
| Jeremy Affeldt* | Bos | mr | 27 | 3 | 4 | 0 | 4 | 0 | 0 | 3 | 2 | 9.1 | 4.5 | 14.0 | 4.2 | 1.6 | 0.9 | 1.51 |
| Cha Seung Baek | NYY | sp | 26 | 2 | 1 | 0 | 3 | 1 | 0 | 0 | 0 | 6.5 | 2.6 | 9.8 | 7.6 | 2.0 | 2.9 | 1.02 |
| Danys Baez | Mtl | mr | 28 | 4 | 1 | 2 | 9 | 3 | 0 | 1 | 8 | 10.5 | 2.3 | 13.8 | 5.1 | 0.8 | 2.2 | 1.42 |
| Kevin Barry | Sea | mr | 27 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10.1 | 6.8 | 16.9 | 11.8 | 3.4 | 1.8 | 1.88 |
| Miguel Batista | Sea | sp | 35 | 6 | 4 | 4 | 3 | 7 | 1 | 1 | 6 | 10.3 | 3.8 | 14.3 | 4.3 | 1.0 | 1.1 | 1.57 |
| Rick Bauer | Sea | mr | 29 | 5 | 3 | 1 | 6 | 3 | 0 | 2 | 1 | 7.1 | 2.7 | 10.4 | 4.6 | 0.6 | 1.7 | 1.09 |
| Jonah Bayliss | ChW | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.0 | 9.0 | 9.0 | 0.0 | 0.0 | 0.0 | 1.00 |
| Josh Beckett | KCR | sp | 26 | 4 | 5 | 5 | 7 | 3 | 1 | 2 | 1 | 7.5 | 2.4 | 10.2 | 6.7 | 1.7 | 2.8 | 1.10 |
| Joe Beimel* | Det | mr | 29 | 2 | 1 | 2 | 3 | 4 | 1 | 3 | 2 | 7.3 | 1.3 | 9.2 | 4.0 | 0.6 | 3.2 | 0.95 |
| Armando Benitez | ChW | cl | 33 | 2 | 1 | 0 | 1 | 0 | 0 | 1 | 2 | 12.7 | 6.5 | 19.6 | 7.4 | 2.9 | 1.1 | 2.14 |
| Joaquin Benoit | Tor | mr | 28 | 5 | 2 | 4 | 4 | 2 | 0 | 3 | 1 | 7.6 | 3.5 | 11.3 | 10.1 | 0.8 | 2.9 | 1.23 |
| Kris Benson | ChW | sp | 31 | 6 | 4 | 1 | 9 | 3 | 0 | 2 | 6 | 9.9 | 2.5 | 12.8 | 4.3 | 1.9 | 1.7 | 1.38 |
| Jason Bergmann | KCR | mr | 24 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.4 | 10.8 | 21.6 | 21.6 | 0.0 | 2.0 | 1.80 |
| Adam Bernero | Oak | sp | 29 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 7.7 | 2.6 | 10.3 | 7.1 | 0.6 | 2.8 | 1.14 |
| Rafael Betancourt | Oak | mr | 31 | 3 | 1 | 1 | 1 | 1 | 0 | 2 | 1 | 6.6 | 0.8 | 7.5 | 5.8 | 0.3 | 7.5 | 0.82 |
| Jeremy Bonderman | Oak | sp | 23 | 23 | 4 | 2 | 4 | 1 | 2 | 4 | 6 | 8.9 | 2.4 | 11.4 | 8.6 | 0.6 | 3.6 | 1.25 |
| Joe Borowski | KCR | cl | 35 | 5 | 2 | 1 | 4 | 0 | 0 | 1 | 7 | 8.6 | 3.3 | 12.3 | 10.1 | 0.9 | 3.0 | 1.33 |
| Chad Bradford | Bos | mr | 31 | 3 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 9.5 | 2.0 | 11.5 | 6.8 | 0.3 | 3.4 | 1.28 |
| Bill Bray* | Bos | mr | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 9.0 | 4.7 | 13.7 | 5.8 | 0.7 | 1.2 | 1.52 |
| Craig Breslow* | Bal | mr | 25 | 0 | 0 | 1 | 1 | 4 | 2 | 0 | 0 | 13.5 | 8.4 | 23.6 | 5.1 | 1.7 | 0.6 | 2.44 |
| Chris Britton | Cle | mr | 23 | 3 | 1 | 0 | 2 | 0 | 0 | 1 | 4 | 7.8 | 2.9 | 11.1 | 6.2 | 0.4 | 2.1 | 1.19 |
| Doug Brocail | KCR | mr | 39 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 8.3 | 2.6 | 10.9 | 7.7 | 0.2 | 3.0 | 1.21 |
| Brian Bruney | Cle | mr | 24 | 0 | 0 | 0 | 1 | 2 | 0 | 1 | 0 | 5.6 | 5.6 | 11.6 | 8.1 | 0.4 | 1.4 | 1.25 |
| Taylor Buchholz | ChW | sp | 24 | 4 | 1 | 1 | 2 | 3 | 0 | 2 | 3 | 8.9 | 2.0 | 11.1 | 5.5 | 1.9 | 2.7 | 1.21 |
| Paul Byrd | Tor | sp | 35 | 13 | 3 | 13 | 6 | 1 | 0 | 4 | 6 | 11.8 | 2.3 | 14.4 | 3.8 | 1.3 | 1.6 | 1.57 |
| Daniel Cabrera | Cle | sp | 25 | 14 | 7 | 0 | 8 | 17 | 1 | 5 | 9 | 9.2 | 6.6 | 16.2 | 10.5 | 0.7 | 1.6 | 1.75 |
| Matt Cain | NYY | sp | 21 | 18 | 5 | 4 | 3 | 5 | 1 | 3 | 12 | 8.1 | 4.6 | 12.8 | 8.9 | 0.8 | 1.9 | 1.41 |
| Kiko Calero | Bal | mr | 31 | 6 | 4 | 1 | 1 | 1 | 0 | 2 | 3 | 8.8 | 4.2 | 13.1 | 10.7 | 1.0 | 2.6 | 1.44 |
| Shawn Camp | Oak | mr | 30 | 2 | 0 | 2 | 5 | 0 | 0 | 0 | 1 | 11.8 | 1.7 | 14.6 | 6.0 | 0.6 | 3.5 | 1.50 |
| Matt Capps | Sea | mr | 22 | 2 | 1 | 1 | 3 | 5 | 0 | 2 | 1 | 8.9 | 1.5 | 10.8 | 7.8 | 1.3 | 5.2 | 1.16 |
| Chris Capuano* | NYY | sp | 27 | 4 | 8 | 3 | 4 | 6 | 0 | 2 | 4 | 11.5 | 2.2 | 13.8 | 6.5 | 1.4 | 3.0 | 1.52 |
| Chris Carpenter | Tex | sp | 31 | 8 | 2 | 2 | 10 | 6 | 0 | 1 | 6 | 9.2 | 2.0 | 11.6 | 7.2 | 0.8 | 3.6 | 1.24 |
| Hector Carrasco | Min | mr | 36 | 8 | 3 | 1 | 3 | 4 | 0 | 1 | 2 | 6.8 | 2.7 | 9.7 | 7.1 | 1.3 | 2.6 | 1.06 |
| Fabio Castro* | Tor | mr | 21 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 6.4 | 1.3 | 9.0 | 6.4 | 0.0 | 5.0 | 0.86 |
| Gustavo Chacin* | Bal | sp | 25 | 1 | 2 | 0 | 6 | 0 | 0 | 3 | 3 | 10.3 | 2.5 | 13.3 | 5.9 | 2.0 | 2.4 | 1.42 |
| Shawn Chacon | Det | sp | 28 | 0 | 0 | 3 | 8 | 2 | 1 | 0 | 5 | 11.4 | 4.6 | 16.7 | 5.8 | 2.0 | 1.3 | 1.78 |
| Bruce Chen* | Cle | mr | 29 | 5 | 2 | 2 | 1 | 1 | 0 | 2 | 4 | 12.5 | 4.0 | 16.7 | 6.9 | 1.2 | 1.7 | 1.84 |
| Vinnie Chulk | Tex | mr | 27 | 4 | 0 | 1 | 2 | 3 | 0 | 1 | 6 | 10.3 | 3.7 | 14.3 | 7.7 | 0.9 | 2.1 | 1.56 |
| Brandon Claussen* | LAA | sp | 27 | 8 | 1 | 1 | 9 | 0 | 0 | 0 | 3 | 11.4 | 3.6 | 16.0 | 7.0 | 1.1 | 1.9 | 1.67 |
| Bartolo Colon | Sea | sp | 33 | 1 | 3 | 5 | 4 | 0 | 0 | 2 | 0 | 10.0 | 1.5 | 12.0 | 5.5 | 1.8 | 3.6 | 1.29 |
| Clay Condrey | Bos | mr | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 0.0 | 9.0 | 3.0 | 2.0 | 99.0 | 1.00 |
| Tim Corcoran | Tex | sp | 28 | 9 | 3 | 4 | 4 | 0 | 2 | 1 | 2 | 8.1 | 4.6 | 12.9 | 5.9 | 1.0 | 1.3 | 1.41 |
| Francisco Cordero | Tex | cl | 31 | 2 | 0 | 8 | 2 | 9 | 0 | 4 | 6 | 9.7 | 4.2 | 14.1 | 7.5 | 1.1 | 1.8 | 1.55 |
| Lance Cormier | Oak | mr | 25 | 5 | 3 | 1 | 2 | 2 | 0 | 1 | 3 | 13.1 | 3.5 | 16.9 | 6.1 | 1.6 | 1.8 | 1.85 |
| Manuel Corpas | Mtl | mr | 23 | 2 | 1 | 0 | 4 | 2 | 0 | 0 | 0 | 10.7 | 2.0 | 13.8 | 7.6 | 0.8 | 3.8 | 1.42 |
| Juan Cruz | Min | mr | 27 | 13 | 3 | 0 | 13 | 2 | 0 | 5 | 3 | 8.1 | 3.8 | 12.7 | 8.2 | 0.6 | 2.2 | 1.32 |
| Jason Davis | KCR | mr | 26 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 5.4 | 0.8 | 6.9 | 5.4 | 1.5 | 7.0 | 0.69 |
| Zach Day | Bal | sp | 28 | 0 | 0 | 0 | 2 | 1 | 0 | 0 | 1 | 17.8 | 1.8 | 20.9 | 2.5 | 0.6 | 1.3 | 2.18 |
| Manny Delcarmen | Cle | mr | 24 | 3 | 3 | 1 | 1 | 0 | 1 | 3 | 3 | 8.7 | 2.6 | 11.4 | 6.9 | 0.9 | 2.7 | 1.25 |
| Ryan Dempster | LAA | cl | 29 | 2 | 3 | 2 | 2 | 7 | 0 | 1 | 5 | 6.1 | 4.7 | 11.1 | 7.2 | 0.1 | 1.5 | 1.21 |
| Joey Devine | Bos | mr | 22 | 0 | 0 | 0 | 2 | 1 | 1 | 0 | 0 | 5.4 | 8.1 | 18.9 | 5.4 | 2.7 | 0.7 | 1.50 |
| Scott Downs* | LAA | mr | 30 | 0 | 0 | 2 | 4 | 6 | 0 | 0 | 2 | 7.3 | 4.3 | 12.3 | 7.3 | 0.7 | 1.7 | 1.30 |
| Brandon Duckworth | Cle | sp | 30 | 1 | 0 | 0 | 1 | 6 | 0 | 0 | 5 | 11.1 | 4.4 | 15.7 | 7.2 | 0.7 | 1.6 | 1.73 |
| Zach Duke* | Tor | sp | 23 | 10 | 3 | 17 | 6 | 5 | 4 | 3 | 9 | 12.6 | 3.7 | 16.5 | 5.4 | 1.1 | 1.5 | 1.81 |
| Adam Eaton | LAA | sp | 28 | 3 | 3 | 2 | 5 | 0 | 0 | 1 | 6 | 10.5 | 3.1 | 14.1 | 5.8 | 1.8 | 1.9 | 1.51 |
| Joey Eischen* | Mtl | mr | 36 | 1 | 0 | 3 | 1 | 1 | 0 | 0 | 0 | 14.8 | 10.9 | 26.1 | 10.9 | 1.3 | 1.0 | 2.85 |
| Kelvim Escobar | Min | sp | 30 | 14 | 3 | 2 | 9 | 11 | 0 | 4 | 6 | 9.5 | 2.5 | 12.4 | 7.0 | 0.9 | 2.8 | 1.33 |
| Shawn Estes* | Oak | sp | 33 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 10.8 | 3.2 | 14.4 | 4.0 | 0.0 | 1.2 | 1.56 |
| Seth Etherton | ChW | sp | 29 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 19.6 | 5.6 | 25.1 | 8.4 | 2.8 | 1.5 | 2.79 |
| Dana Eveland* | Cle | sp | 22 | 1 | 1 | 1 | 9 | 4 | 0 | 0 | 1 | 11.4 | 3.7 | 16.8 | 9.9 | 2.4 | 2.7 | 1.67 |
| Willie Eyre | NYY | mr | 27 | 5 | 3 | 7 | 8 | 5 | 0 | 2 | 5 | 8.0 | 2.5 | 11.2 | 3.8 | 1.3 | 1.5 | 1.16 |
| Kyle Farnsworth | Det | mr | 30 | 3 | 2 | 0 | 0 | 4 | 0 | 0 | 1 | 8.9 | 3.0 | 11.9 | 9.4 | 1.1 | 3.1 | 1.32 |
| Ryan Feierabend* | Det | sp | 20 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 6.2 | 3.5 | 9.7 | 6.9 | 1.4 | 2.0 | 1.08 |
| Pedro Feliciano* | NYY | mr | 29 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 2 | 9.1 | 3.4 | 12.7 | 8.2 | 0.6 | 2.4 | 1.39 |
| Ron Flores* | KCR | mr | 26 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 6.3 | 3.0 | 9.3 | 6.3 | 1.5 | 2.1 | 1.03 |
| Casey Fossum* | KCR | sp | 28 | 3 | 1 | 0 | 7 | 0 | 0 | 0 | 2 | 10.2 | 2.9 | 13.6 | 6.6 | 1.8 | 2.3 | 1.46 |
| Keith Foulke | Oak | mr | 33 | 1 | 0 | 2 | 6 | 3 | 0 | 0 | 2 | 7.9 | 1.0 | 9.8 | 6.8 | 1.1 | 7.2 | 0.99 |
| Jeff Francis* | Bos | sp | 25 | 12 | 1 | 1 | 15 | 0 | 0 | 6 | 8 | 8.1 | 2.9 | 11.6 | 5.3 | 0.9 | 1.9 | 1.23 |
| Ryan Franklin | Tex | mr | 33 | 2 | 0 | 1 | 2 | 3 | 0 | 2 | 2 | 10.1 | 4.2 | 14.5 | 3.8 | 1.0 | 0.9 | 1.59 |
| Brian Fuentes* | Bal | cl | 30 | 3 | 3 | 7 | 8 | 12 | 0 | 3 | 7 | 7.8 | 4.2 | 12.7 | 9.7 | 1.2 | 2.3 | 1.33 |
| Aaron Fultz* | Cle | mr | 32 | 0 | 2 | 0 | 2 | 1 | 0 | 0 | 2 | 9.8 | 2.7 | 12.8 | 9.0 | 0.8 | 3.3 | 1.38 |
| Kason Gabbard* | Tor | sp | 24 | 0 | 1 | 0 | 0 | 2 | 0 | 0 | 3 | 9.0 | 7.3 | 16.3 | 3.9 | 0.5 | 0.5 | 1.81 |
| Jon Garland | Mtl | sp | 26 | 10 | 3 | 2 | 9 | 1 | 0 | 2 | 9 | 11.1 | 1.6 | 13.0 | 5.3 | 1.2 | 3.4 | 1.40 |
| Matt Garza | Bal | sp | 22 | 3 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 14.6 | 4.5 | 19.1 | 6.8 | 1.1 | 1.5 | 2.13 |
| Geoff Geary | LAA | mr | 29 | 9 | 2 | 3 | 6 | 0 | 0 | 0 | 3 | 10.0 | 2.0 | 12.4 | 6.2 | 0.4 | 3.2 | 1.32 |
| Jimmy Gobble* | Cle | mr | 24 | 5 | 1 | 2 | 1 | 3 | 0 | 1 | 4 | 9.3 | 3.7 | 13.0 | 8.6 | 1.4 | 2.3 | 1.44 |
| Enrique Gonzalez | KCR | sp | 23 | 1 | 0 | 0 | 4 | 1 | 0 | 1 | 0 | 10.1 | 3.7 | 14.5 | 4.9 | 1.3 | 1.3 | 1.54 |
| Geremi Gonzalez | Oak | mr | 31 | 8 | 1 | 2 | 1 | 1 | 0 | 1 | 3 | 15.1 | 3.6 | 18.8 | 8.0 | 2.7 | 2.3 | 2.07 |
| Tom Gordon | Bal | cl | 38 | 4 | 1 | 0 | 1 | 3 | 0 | 5 | 4 | 8.7 | 2.7 | 11.4 | 8.8 | 1.3 | 3.3 | 1.26 |
| Tom Gorzelanny* | Sea | sp | 23 | 3 | 1 | 1 | 4 | 4 | 0 | 2 | 4 | 7.2 | 4.6 | 12.2 | 6.9 | 0.8 | 1.5 | 1.31 |
| John Grabow* | KCR | mr | 27 | 3 | 1 | 1 | 3 | 0 | 0 | 0 | 1 | 8.6 | 3.7 | 12.7 | 10.1 | 0.7 | 2.8 | 1.36 |
| Zack Greinke | Bos | mr | 22 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.7 | 1.9 | 9.6 | 1.9 | 1.9 | 1.0 | 1.07 |
| Eddie Guardado* | Mtl | cl | 35 | 1 | 0 | 5 | 3 | 0 | 0 | 1 | 0 | 12.8 | 4.3 | 17.6 | 10.3 | 3.2 | 2.4 | 1.90 |
| Charlie Haeger | Cle | mr | 22 | 1 | 2 | 0 | 0 | 0 | 1 | 1 | 7 | 6.0 | 8.0 | 14.0 | 8.2 | 0.2 | 1.0 | 1.56 |
| Jason Hammel | ChW | sp | 23 | 3 | 1 | 1 | 2 | 3 | 0 | 0 | 1 | 13.8 | 6.9 | 21.2 | 6.5 | 1.6 | 0.9 | 2.31 |
| Chris Hammond* | Tor | mr | 40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 1.3 | 10.3 | 6.4 | 2.6 | 5.0 | 1.14 |
| Josh Hancock | NYY | mr | 28 | 2 | 1 | 1 | 3 | 1 | 1 | 1 | 5 | 8.7 | 2.9 | 12.0 | 5.0 | 0.9 | 1.7 | 1.29 |
| Aaron Harang | Was | sp | 28 | 8 | 1 | 1 | 6 | 5 | 1 | 1 | 4 | 12.3 | 2.1 | 14.9 | 9.0 | 1.5 | 4.4 | 1.60 |
| Travis Harper | LAA | mr | 30 | 1 | 0 | 0 | 3 | 0 | 0 | 0 | 3 | 19.6 | 4.7 | 25.3 | 7.1 | 2.0 | 1.5 | 2.70 |
| Chad Harville | Det | mr | 29 | 2 | 0 | 1 | 0 | 2 | 1 | 0 | 4 | 8.3 | 6.6 | 15.0 | 6.4 | 1.2 | 1.0 | 1.66 |
| LaTroy Hawkins | Cle | mr | 33 | 6 | 1 | 4 | 1 | 1 | 0 | 0 | 1 | 11.1 | 2.5 | 13.8 | 4.7 | 0.6 | 1.9 | 1.52 |
| Aaron Heilman | Oak | mr | 27 | 6 | 1 | 2 | 1 | 1 | 0 | 0 | 5 | 8.0 | 4.1 | 12.2 | 8.2 | 0.8 | 2.0 | 1.34 |
| Rick Helling | Bos | mr | 35 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 3 | 7.9 | 2.1 | 10.3 | 8.5 | 3.0 | 4.0 | 1.11 |
| Mark Hendrickson* | LAA | sp | 32 | 24 | 3 | 4 | 6 | 10 | 0 | 5 | 11 | 9.7 | 3.3 | 13.3 | 6.0 | 0.7 | 1.8 | 1.44 |
| Sean Henn* | Tex | mr | 25 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10.8 | 4.0 | 14.8 | 6.8 | 0.0 | 1.7 | 1.65 |
| Clay Hensley | Bal | sp | 26 | 6 | 4 | 0 | 5 | 3 | 0 | 5 | 10 | 9.8 | 3.5 | 13.5 | 5.6 | 0.8 | 1.6 | 1.47 |
| Felix Hernandez | Min | sp | 20 | 14 | 10 | 5 | 4 | 5 | 0 | 1 | 5 | 8.6 | 2.3 | 11.1 | 7.8 | 0.9 | 3.4 | 1.21 |
| Livan Hernandez | Was | sp | 31 | 13 | 6 | 0 | 4 | 2 | 0 | 5 | 7 | 10.3 | 2.7 | 13.1 | 4.3 | 1.2 | 1.6 | 1.44 |
| Orlando Hernandez | Sea | sp | 36 | 9 | 3 | 7 | 4 | 1 | 5 | 5 | 6 | 8.8 | 4.0 | 13.0 | 8.9 | 1.6 | 2.2 | 1.42 |
| Roberto Hernandez | Tor | mr | 41 | 4 | 3 | 10 | 1 | 4 | 0 | 3 | 3 | 9.8 | 4.2 | 14.0 | 6.8 | 1.2 | 1.6 | 1.55 |
| Runelvys Hernandez | ChW | sp | 28 | 4 | 3 | 0 | 8 | 3 | 2 | 3 | 9 | 13.4 | 3.9 | 17.8 | 3.8 | 2.1 | 1.0 | 1.92 |
| Jason Hirsh | Tex | sp | 24 | 15 | 0 | 0 | 8 | 4 | 0 | 1 | 9 | 9.4 | 5.1 | 15.3 | 5.9 | 1.9 | 1.2 | 1.62 |
| J.P. Howell* | Bos | sp | 23 | 5 | 1 | 0 | 5 | 0 | 0 | 0 | 2 | 9.1 | 2.9 | 12.8 | 8.6 | 0.5 | 2.9 | 1.34 |
| Tim Hudson | Det | sp | 30 | 19 | 2 | 4 | 6 | 4 | 0 | 6 | 9 | 10.8 | 2.9 | 14.0 | 5.9 | 1.1 | 2.0 | 1.52 |
| Jason Isringhausen | Bos | cl | 33 | 7 | 1 | 0 | 0 | 3 | 0 | 2 | 2 | 5.1 | 4.5 | 9.6 | 8.7 | 0.9 | 1.9 | 1.06 |
| Edwin Jackson | Min | mr | 22 | 2 | 2 | 1 | 3 | 5 | 0 | 1 | 1 | 8.3 | 7.2 | 16.0 | 7.3 | 0.6 | 1.0 | 1.71 |
| Zach Jackson* | Tex | sp | 23 | 4 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 9.7 | 5.5 | 15.7 | 3.9 | 1.6 | 0.7 | 1.69 |
| Chuck James* | Bos | sp | 24 | 7 | 1 | 1 | 4 | 0 | 0 | 3 | 2 | 8.5 | 3.9 | 12.7 | 7.1 | 1.4 | 1.8 | 1.38 |
| Bobby Jenks | KCR | cl | 25 | 3 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 9.0 | 2.4 | 11.4 | 11.0 | 0.5 | 4.6 | 1.27 |
| Tyler Johnson* | Sea | mr | 25 | 7 | 2 | 8 | 3 | 6 | 1 | 0 | 3 | 8.5 | 8.6 | 17.6 | 9.1 | 1.1 | 1.1 | 1.90 |
| Todd Jones | Mtl | cl | 38 | 1 | 1 | 3 | 2 | 3 | 0 | 0 | 3 | 7.1 | 1.7 | 9.1 | 3.8 | 0.3 | 2.2 | 0.99 |
| Scott Kazmir* | Bos | sp | 22 | 6 | 2 | 2 | 5 | 5 | 0 | 5 | 4 | 8.4 | 2.8 | 11.5 | 10.5 | 0.7 | 3.8 | 1.25 |
| Randy Keisler* | Mtl | mr | 30 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 10.5 | 2.6 | 13.1 | 4.4 | 1.7 | 1.7 | 1.45 |
| Joe Kennedy* | Min | mr | 27 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 3 | 7.2 | 1.7 | 9.1 | 8.6 | 0.2 | 5.0 | 0.99 |
| Logan Kensing | Was | mr | 23 | 2 | 1 | 2 | 7 | 1 | 0 | 0 | 3 | 8.6 | 5.0 | 14.5 | 10.3 | 1.8 | 2.0 | 1.51 |
| Bobby Keppel | Bal | sp | 24 | 1 | 1 | 3 | 2 | 1 | 0 | 2 | 1 | 11.1 | 2.6 | 14.0 | 5.4 | 1.5 | 2.0 | 1.53 |
| Byung-Hyun Kim | Bos | sp | 27 | 12 | 1 | 3 | 8 | 6 | 0 | 0 | 8 | 10.5 | 4.4 | 15.4 | 6.9 | 0.9 | 1.6 | 1.67 |
| Dan Kolb | ChW | mr | 31 | 1 | 1 | 0 | 1 | 4 | 0 | 1 | 2 | 12.9 | 2.3 | 15.5 | 4.5 | 1.2 | 1.9 | 1.70 |
| Hong-Chih Kuo* | Bos | mr | 24 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 4 | 9.8 | 5.5 | 15.4 | 12.3 | 0.8 | 2.3 | 1.69 |
| John Lackey | Bal | sp | 27 | 17 | 10 | 0 | 10 | 14 | 0 | 5 | 5 | 9.2 | 2.7 | 12.2 | 7.3 | 0.7 | 2.7 | 1.32 |
| Brandon League | Min | mr | 23 | 5 | 3 | 1 | 2 | 0 | 0 | 1 | 1 | 8.5 | 1.0 | 9.8 | 6.5 | 0.3 | 6.2 | 1.06 |
| Brad Lidge | ChW | cl | 29 | 0 | 3 | 3 | 2 | 16 | 0 | 2 | 0 | 9.4 | 4.9 | 14.6 | 13.3 | 1.4 | 2.7 | 1.59 |
| Francisco Liriano* | Min | sp | 22 | 15 | 1 | 2 | 3 | 14 | 0 | 2 | 0 | 7.5 | 2.1 | 9.8 | 10.8 | 0.7 | 5.2 | 1.07 |
| Esteban Loaiza | LAA | sp | 34 | 13 | 7 | 2 | 5 | 0 | 0 | 3 | 5 | 11.1 | 1.8 | 13.3 | 6.7 | 0.9 | 3.6 | 1.44 |
| Kameron Loe | NYY | sp | 24 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 12.9 | 2.8 | 15.8 | 2.8 | 1.7 | 1.0 | 1.75 |
| Boone Logan* | ChW | mr | 21 | 3 | 1 | 0 | 2 | 2 | 1 | 0 | 3 | 9.2 | 4.9 | 15.1 | 8.6 | 0.5 | 1.8 | 1.56 |
| Javier Lopez* | Tex | mr | 28 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 20.3 | 6.8 | 27.0 | 13.5 | 0.0 | 2.0 | 3.00 |
| Rodrigo Lopez | NYY | sp | 30 | 9 | 0 | 2 | 5 | 4 | 2 | 2 | 10 | 10.1 | 3.2 | 13.5 | 6.5 | 1.1 | 2.0 | 1.47 |
| Mark Lowe | Bos | mr | 23 | 2 | 0 | 0 | 3 | 1 | 0 | 1 | 0 | 10.2 | 4.0 | 14.9 | 9.3 | 0.5 | 2.4 | 1.58 |
| Ruddy Lugo | Was | mr | 26 | 1 | 2 | 1 | 5 | 3 | 0 | 2 | 6 | 8.3 | 3.8 | 12.6 | 5.6 | 0.7 | 1.5 | 1.34 |
| Ryan Madson | NYY | mr | 25 | 2 | 1 | 1 | 6 | 9 | 0 | 2 | 6 | 15.1 | 3.1 | 19.0 | 5.8 | 1.4 | 1.9 | 2.02 |
| Carlos Marmol | Bal | sp | 23 | 10 | 1 | 1 | 2 | 6 | 1 | 1 | 6 | 9.0 | 7.7 | 16.9 | 6.4 | 2.0 | 0.8 | 1.85 |
| Mike Maroth* | Tor | sp | 28 | 2 | 4 | 2 | 3 | 1 | 0 | 1 | 4 | 11.6 | 2.3 | 14.2 | 3.8 | 1.2 | 1.6 | 1.55 |
| Damaso Marte* | Was | mr | 31 | 3 | 0 | 0 | 1 | 4 | 1 | 1 | 2 | 6.5 | 5.6 | 12.2 | 9.7 | 0.9 | 1.7 | 1.34 |
| Carlos Martinez | Mtl | mr | 24 | 5 | 0 | 0 | 0 | 1 | 0 | 0 | 2 | 7.4 | 3.4 | 10.9 | 8.7 | 0.3 | 2.5 | 1.21 |
| Tom Mastny | Tex | cl | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 9.0 | 18.0 | 0.0 | 9.0 | 0.0 | 2.00 |
| Juan Mateo | KCR | sp | 23 | 2 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 10.9 | 4.0 | 15.3 | 9.7 | 0.8 | 2.4 | 1.66 |
| Dustin McGowan | Cle | mr | 24 | 2 | 1 | 1 | 1 | 5 | 1 | 2 | 4 | 12.2 | 7.5 | 19.9 | 7.3 | 0.4 | 1.0 | 2.19 |
| Marty McLeary | NYY | mr | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.4 | 4.3 | 5.7 | 2.8 | 0.0 | 0.7 | 0.63 |
| Brian Meadows | Bal | mr | 30 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11.4 | 1.1 | 12.5 | 6.8 | 2.7 | 6.0 | 1.39 |
| Gil Meche |   | sp | 27 | 12 | 5 | 1 | 10 | 3 | 0 | 3 | 6 | 9.7 | 3.6 | 13.9 | 7.7 | 1.4 | 2.1 | 1.48 |
| Brandon Medders | Mtl | mr | 26 | 6 | 1 | 9 | 7 | 2 | 0 | 0 | 6 | 9.2 | 3.8 | 13.5 | 5.4 | 0.6 | 1.4 | 1.44 |
| Jose Mesa | Bal | mr | 40 | 1 | 0 | 1 | 14 | 12 | 0 | 3 | 5 | 9.6 | 3.6 | 14.3 | 4.8 | 0.8 | 1.4 | 1.46 |
| Dan Miceli | Tor | mr | 35 | 0 | 1 | 2 | 1 | 3 | 0 | 1 | 0 | 6.8 | 3.4 | 10.6 | 8.0 | 1.1 | 2.3 | 1.14 |
| Trever Miller* | Det | mr | 33 | 3 | 2 | 0 | 5 | 1 | 1 | 0 | 0 | 8.3 | 1.7 | 10.7 | 10.9 | 0.9 | 6.3 | 1.11 |
| Eric Milton* | Cle | sp | 30 | 7 | 3 | 2 | 6 | 5 | 0 | 3 | 3 | 10.9 | 2.3 | 13.5 | 5.9 | 1.6 | 2.6 | 1.46 |
| Zach Miner | Det | sp | 24 | 3 | 3 | 6 | 0 | 0 | 0 | 4 | 2 | 10.3 | 3.1 | 13.3 | 6.1 | 1.0 | 2.0 | 1.48 |
| Brian Moehler | Sea | sp | 34 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 12.0 | 2.3 | 14.5 | 4.1 | 0.8 | 1.8 | 1.58 |
| Matt Morris | Mtl | sp | 31 | 13 | 0 | 6 | 3 | 1 | 1 | 5 | 9 | 11.1 | 2.9 | 14.3 | 4.8 | 1.1 | 1.6 | 1.56 |
| Jamie Moyer* | Tor | sp | 43 | 13 | 4 | 12 | 4 | 0 | 0 | 2 | 3 | 10.9 | 2.6 | 13.6 | 5.1 | 1.3 | 2.0 | 1.49 |
| Edward Mujica | Cle | mr | 22 | 0 | 0 | 0 | 3 | 0 | 1 | 0 | 2 | 14.8 | 0.0 | 16.3 | 6.1 | 1.5 | 99.0 | 1.64 |
| Mark Mulder* | Was | sp | 28 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 14.7 | 9.8 | 24.5 | 3.7 | 1.2 | 0.4 | 2.73 |
| Scott Munter | NYY | mr | 26 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 2 | 12.2 | 2.5 | 15.3 | 3.6 | 1.0 | 1.4 | 1.64 |
| Brett Myers | Oak | sp | 25 | 14 | 8 | 0 | 4 | 2 | 0 | 2 | 5 | 9.0 | 3.0 | 12.2 | 8.2 | 0.9 | 2.7 | 1.34 |
| Chris Narveson* | Min | mr | 24 | 1 | 1 | 2 | 1 | 2 | 0 | 0 | 1 | 6.0 | 5.0 | 11.3 | 11.3 | 0.3 | 2.3 | 1.22 |
| Joe Nathan | Was | cl | 31 | 0 | 1 | 1 | 0 | 4 | 0 | 0 | 0 | 3.5 | 1.2 | 4.7 | 12.2 | 0.3 | 10.1 | 0.52 |
| Joe Nelson | ChW | mr | 31 | 1 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 6.9 | 2.1 | 9.5 | 8.1 | 1.2 | 3.8 | 1.00 |
| Fernando Nieve | Bos | mr | 23 | 5 | 6 | 0 | 3 | 0 | 0 | 2 | 2 | 9.3 | 3.9 | 13.4 | 5.6 | 2.1 | 1.4 | 1.47 |
| Roberto Novoa | Sea | mr | 26 | 7 | 2 | 1 | 9 | 3 | 0 | 0 | 6 | 8.8 | 3.4 | 13.0 | 6.6 | 1.7 | 1.9 | 1.36 |
| Mike O'Connor* | KCR | sp | 25 | 7 | 4 | 1 | 4 | 9 | 0 | 0 | 2 | 10.4 | 3.9 | 14.7 | 5.2 | 1.1 | 1.4 | 1.59 |
| Ryan O'Malley* | Was | sp | 26 | 2 | 0 | 0 | 2 | 1 | 1 | 5 | 6 | 8.2 | 7.4 | 16.1 | 1.9 | 0.0 | 0.3 | 1.74 |
| Darren Oliver* |   | mr | 35 | 5 | 1 | 5 | 3 | 1 | 0 | 1 | 2 | 7.5 | 3.5 | 11.3 | 7.0 | 1.0 | 2.0 | 1.22 |
| Ramon Ortiz | NYY | sp | 33 | 4 | 4 | 2 | 13 | 2 | 6 | 2 | 11 | 13.0 | 2.5 | 16.3 | 5.0 | 1.6 | 2.0 | 1.73 |
| Russ Ortiz | Tor | mr | 32 | 1 | 0 | 4 | 1 | 1 | 0 | 1 | 2 | 13.1 | 4.8 | 18.1 | 7.7 | 1.4 | 1.6 | 1.99 |
| Vicente Padilla | KCR | sp | 28 | 12 | 3 | 3 | 20 | 4 | 2 | 4 | 8 | 8.4 | 3.0 | 12.3 | 7.2 | 0.9 | 2.4 | 1.26 |
| Jonathan Papelbon | Min | cl | 25 | 7 | 2 | 1 | 1 | 0 | 0 | 2 | 2 | 4.6 | 1.5 | 6.2 | 8.1 | 0.2 | 5.3 | 0.68 |
| Chan Ho Park | ChW | sp | 33 | 4 | 5 | 1 | 10 | 9 | 0 | 2 | 4 | 9.2 | 2.3 | 12.0 | 6.5 | 1.0 | 2.8 | 1.27 |
| Jake Peavy | ChW | sp | 25 | 8 | 5 | 0 | 5 | 4 | 0 | 8 | 5 | 9.6 | 2.4 | 12.2 | 10.0 | 1.3 | 4.1 | 1.33 |
| Tony Pena | Oak | mr | 24 | 1 | 2 | 2 | 0 | 1 | 0 | 0 | 2 | 8.6 | 2.2 | 10.8 | 6.0 | 0.5 | 2.8 | 1.19 |
| Joel Peralta | Tex | mr | 30 | 2 | 3 | 7 | 5 | 6 | 0 | 1 | 6 | 8.1 | 3.8 | 12.4 | 6.1 | 0.7 | 1.6 | 1.33 |
| Odalis Perez* | Min | sp | 29 | 14 | 1 | 1 | 8 | 6 | 3 | 6 | 7 | 10.6 | 1.9 | 12.9 | 5.9 | 1.2 | 3.1 | 1.39 |
| Oliver Perez* | LAA | sp | 24 | 4 | 4 | 1 | 3 | 3 | 0 | 4 | 2 | 10.1 | 7.0 | 17.5 | 7.5 | 1.6 | 1.1 | 1.90 |
| Joel Pineiro | Sea | sp | 27 | 9 | 0 | 2 | 7 | 0 | 0 | 3 | 2 | 10.8 | 2.9 | 14.2 | 4.3 | 1.8 | 1.5 | 1.52 |
| Mark Prior | KCR | sp | 25 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 4.8 | 5.6 | 11.9 | 4.0 | 0.0 | 0.7 | 1.15 |
| Scott Proctor | NYY | mr | 29 | 2 | 4 | 3 | 2 | 2 | 0 | 3 | 3 | 7.6 | 2.1 | 9.9 | 7.0 | 1.6 | 3.3 | 1.08 |
| Brad Radke | Was | sp | 33 | 3 | 0 | 1 | 0 | 1 | 0 | 0 | 2 | 14.1 | 2.3 | 16.4 | 4.8 | 1.7 | 2.1 | 1.82 |
| Horacio Ramirez* | Tex | sp | 26 | 15 | 4 | 0 | 11 | 0 | 0 | 1 | 5 | 10.5 | 3.8 | 15.0 | 4.5 | 1.0 | 1.2 | 1.58 |
| Chris Ray | Cle | cl | 24 | 3 | 0 | 3 | 4 | 1 | 0 | 1 | 1 | 5.4 | 3.5 | 9.6 | 6.6 | 0.7 | 1.9 | 0.99 |
| Mark Redman* | Mtl | sp | 32 | 7 | 2 | 10 | 6 | 11 | 1 | 2 | 8 | 10.7 | 3.1 | 14.1 | 3.9 | 1.1 | 1.3 | 1.53 |
| Chris Resop | Cle | mr | 23 | 3 | 3 | 0 | 1 | 0 | 0 | 1 | 1 | 12.5 | 4.8 | 17.5 | 3.0 | 0.4 | 0.6 | 1.92 |
| Anthony Reyes | KCR | sp | 24 | 3 | 2 | 0 | 7 | 1 | 0 | 1 | 1 | 12.4 | 3.8 | 17.5 | 6.5 | 3.0 | 1.7 | 1.80 |
| David Riske | ChW | mr | 29 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 11.3 | 5.4 | 16.6 | 6.8 | 1.3 | 1.3 | 1.85 |
| Mariano Rivera | Tor | cl | 36 | 5 | 0 | 1 | 7 | 0 | 0 | 1 | 3 | 8.9 | 0.9 | 10.4 | 6.4 | 0.4 | 7.4 | 1.09 |
| Francisco Rodriguez | Tor | cl | 24 | 9 | 3 | 7 | 2 | 12 | 0 | 1 | 2 | 7.4 | 2.6 | 10.2 | 11.5 | 0.9 | 4.4 | 1.11 |
| Kenny Rogers* | LAA | sp | 41 | 9 | 4 | 4 | 8 | 3 | 0 | 2 | 3 | 8.4 | 2.4 | 11.1 | 4.4 | 0.8 | 1.8 | 1.20 |
| Glendon Rusch* | LAA | mr | 31 | 1 | 0 | 0 | 1 | 0 | 0 | 2 | 1 | 14.9 | 3.9 | 19.0 | 8.2 | 2.6 | 2.1 | 2.09 |
| B.J. Ryan* | Was | cl | 30 | 4 | 2 | 4 | 0 | 5 | 0 | 1 | 0 | 3.0 | 2.9 | 5.9 | 10.8 | 0.2 | 3.7 | 0.66 |
| Kirk Saarloos | Bal | mr | 27 | 11 | 6 | 0 | 3 | 8 | 0 | 5 | 5 | 9.7 | 2.7 | 12.6 | 4.4 | 1.4 | 1.7 | 1.37 |
| C.C. Sabathia* |   | sp | 25 | 15 | 2 | 1 | 10 | 3 | 0 | 4 | 9 | 9.6 | 1.8 | 11.8 | 8.7 | 0.6 | 5.0 | 1.26 |
| Juan Salas | Oak | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 40.5 | 0.0 | 40.5 | 6.8 | 6.8 | 99.0 | 4.50 |
| Chris Sampson | NYY | mr | 28 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 7.4 | 0.9 | 9.1 | 3.0 | 0.9 | 3.5 | 0.92 |
| Anibal Sanchez | Was | sp | 22 | 10 | 5 | 1 | 4 | 2 | 1 | 2 | 4 | 7.2 | 4.0 | 11.5 | 4.6 | 0.7 | 1.1 | 1.25 |
| Duaner Sanchez | Mtl | mr | 26 | 3 | 0 | 4 | 3 | 2 | 0 | 0 | 3 | 8.3 | 4.3 | 13.0 | 8.0 | 0.8 | 1.9 | 1.40 |
| Johan Santana* | Sea | sp | 27 | 8 | 2 | 0 | 14 | 3 | 0 | 2 | 2 | 8.2 | 1.6 | 10.4 | 9.5 | 0.8 | 5.8 | 1.10 |
| Scott Sauerbeck* | ChW | mr | 34 | 2 | 0 | 0 | 8 | 0 | 0 | 0 | 2 | 9.5 | 6.9 | 20.6 | 7.4 | 1.1 | 1.1 | 1.82 |
| Joe Saunders* | Cle | sp | 25 | 7 | 5 | 0 | 1 | 2 | 3 | 4 | 1 | 8.9 | 2.8 | 11.7 | 5.1 | 0.5 | 1.8 | 1.29 |
| Scott Schoeneweis* | Tex | mr | 32 | 3 | 2 | 2 | 1 | 2 | 0 | 0 | 3 | 8.0 | 3.8 | 11.9 | 4.4 | 1.1 | 1.2 | 1.31 |
| Chris Schroder | Tex | mr | 27 | 0 | 0 | 1 | 2 | 1 | 0 | 0 | 1 | 5.4 | 9.0 | 18.0 | 10.8 | 0.0 | 1.2 | 1.60 |
| Rudy Seanez | Det | mr | 37 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 2 | 10.5 | 4.8 | 15.3 | 9.3 | 1.6 | 1.9 | 1.70 |
| Bobby Seay* | LAA | mr | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 15.4 | 15.4 | 30.9 | 7.7 | 3.9 | 0.5 | 3.43 |
| Ben Sheets | Oak | sp | 27 | 15 | 2 | 2 | 6 | 1 | 0 | 2 | 1 | 8.9 | 1.0 | 10.2 | 9.5 | 1.0 | 9.2 | 1.10 |
| George Sherrill* | KCR | mr | 29 | 5 | 1 | 2 | 2 | 0 | 0 | 2 | 5 | 7.7 | 4.1 | 12.0 | 9.3 | 0.0 | 2.3 | 1.31 |
| Matt Smith* | Cle | mr | 27 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 5.4 | 3.6 | 9.4 | 8.6 | 0.4 | 2.4 | 1.00 |
| Kyle Snyder | Tex | sp | 28 | 5 | 1 | 2 | 3 | 2 | 0 | 4 | 1 | 12.6 | 2.3 | 15.2 | 8.3 | 1.4 | 3.6 | 1.66 |
| Rafael Soriano | Min | mr | 26 | 5 | 2 | 0 | 3 | 3 | 0 | 0 | 2 | 6.8 | 3.3 | 10.5 | 8.9 | 1.0 | 2.7 | 1.13 |
| Jeremy Sowers* | Det | sp | 23 | 3 | 4 | 2 | 3 | 1 | 0 | 3 | 6 | 8.5 | 2.1 | 10.9 | 3.3 | 1.1 | 1.5 | 1.18 |
| Brian Stokes | Oak | sp | 26 | 0 | 1 | 1 | 3 | 1 | 1 | 1 | 3 | 13.2 | 4.2 | 17.8 | 5.9 | 0.9 | 1.4 | 1.93 |
| Huston Street | NYY | cl | 22 | 4 | 1 | 3 | 2 | 3 | 0 | 3 | 2 | 7.5 | 2.1 | 9.8 | 8.8 | 0.5 | 4.2 | 1.06 |
| Jeff Suppan | Was | sp | 31 | 11 | 3 | 4 | 8 | 7 | 0 | 3 | 4 | 10.4 | 3.5 | 14.3 | 5.1 | 1.1 | 1.5 | 1.54 |
| Taylor Tankersley* | Det | mr | 23 | 3 | 1 | 0 | 2 | 3 | 0 | 0 | 0 | 8.2 | 5.1 | 13.7 | 10.8 | 0.8 | 2.1 | 1.48 |
| Jack Taschner* | NYY | mr | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.00 |
| Ty Taubenheim | ChW | sp | 23 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 4 | 10.8 | 5.1 | 16.2 | 6.9 | 1.5 | 1.4 | 1.77 |
| Mike Timlin | Was | mr | 40 | 0 | 2 | 0 | 2 | 2 | 0 | 0 | 2 | 10.9 | 0.9 | 12.4 | 4.0 | 0.9 | 4.3 | 1.31 |
| Brett Tomko | NYY | mr | 33 | 1 | 1 | 2 | 9 | 2 | 0 | 4 | 8 | 10.0 | 1.7 | 12.2 | 5.9 | 1.5 | 3.5 | 1.30 |
| Salomon Torres | LAA | mr | 34 | 6 | 3 | 2 | 2 | 2 | 0 | 4 | 2 | 9.2 | 2.9 | 12.3 | 7.6 | 0.3 | 2.6 | 1.35 |
| Josh Towers | Tex | sp | 29 | 6 | 0 | 1 | 4 | 1 | 1 | 1 | 3 | 17.8 | 2.3 | 20.8 | 3.0 | 2.1 | 1.3 | 2.23 |
| Steve Trachsel | LAA | sp | 35 | 12 | 3 | 0 | 3 | 3 | 0 | 3 | 7 | 10.2 | 4.6 | 15.0 | 4.4 | 1.7 | 0.9 | 1.64 |
| Jose Veras | Oak | mr | 25 | 1 | 0 | 1 | 0 | 5 | 0 | 0 | 0 | 10.1 | 6.4 | 16.4 | 8.5 | 1.6 | 1.3 | 1.82 |
| Justin Verlander | Cle | sp | 23 | 12 | 6 | 0 | 10 | 11 | 0 | 2 | 10 | 9.4 | 3.3 | 13.1 | 6.2 | 0.9 | 1.9 | 1.41 |
| Ron Villone* | LAA | mr | 36 | 2 | 1 | 3 | 3 | 1 | 0 | 0 | 1 | 9.3 | 3.7 | 13.3 | 8.4 | 0.8 | 2.3 | 1.44 |
| Luis Vizcaino | Bos | mr | 31 | 2 | 2 | 0 | 1 | 0 | 0 | 0 | 5 | 8.1 | 2.5 | 10.7 | 9.0 | 1.3 | 3.6 | 1.18 |
| Ryan Vogelsong | Was | mr | 28 | 2 | 0 | 0 | 5 | 3 | 1 | 0 | 0 | 11.1 | 4.2 | 16.3 | 7.3 | 1.5 | 1.8 | 1.70 |
| Edinson Volquez | Mtl | sp | 22 | 6 | 1 | 0 | 2 | 0 | 0 | 1 | 2 | 11.7 | 3.7 | 15.6 | 3.1 | 1.4 | 0.8 | 1.70 |
| Billy Wagner* | Bos | cl | 34 | 8 | 0 | 2 | 1 | 3 | 0 | 3 | 1 | 8.9 | 3.5 | 12.4 | 12.7 | 0.6 | 3.7 | 1.37 |
| Ryan Wagner | Oak | mr | 23 | 4 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 10.3 | 2.5 | 12.8 | 4.4 | 0.0 | 1.8 | 1.42 |
| Tim Wakefield | Sea | sp | 39 | 26 | 10 | 0 | 13 | 2 | 0 | 2 | 7 | 8.2 | 2.7 | 11.5 | 4.9 | 1.4 | 1.8 | 1.21 |
| John Wasdin | Oak | sp | 33 | 5 | 1 | 0 | 10 | 0 | 0 | 3 | 1 | 8.7 | 3.5 | 14.2 | 4.1 | 1.6 | 1.2 | 1.36 |
| Jarrod Washburn* | Det | sp | 31 | 9 | 5 | 1 | 4 | 1 | 0 | 4 | 8 | 10.4 | 2.5 | 13.0 | 5.2 | 0.8 | 2.1 | 1.43 |
| David Weathers | Det | mr | 36 | 5 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 8.4 | 4.6 | 13.0 | 6.5 | 1.0 | 1.4 | 1.45 |
| Brandon Webb | Det | sp | 27 | 18 | 3 | 3 | 6 | 6 | 2 | 3 | 6 | 8.1 | 2.0 | 10.4 | 6.6 | 0.7 | 3.3 | 1.13 |
| David Wells* | Bal | sp | 43 | 4 | 2 | 1 | 2 | 0 | 0 | 1 | 2 | 13.4 | 1.7 | 15.3 | 4.3 | 1.4 | 2.5 | 1.68 |
| Kip Wells | Mtl | sp | 29 | 2 | 0 | 0 | 7 | 12 | 1 | 2 | 2 | 10.8 | 5.6 | 17.1 | 2.9 | 1.5 | 0.5 | 1.82 |
| Jake Westbrook | Tex | sp | 28 | 19 | 4 | 0 | 4 | 1 | 0 | 2 | 6 | 9.4 | 2.1 | 11.6 | 4.6 | 1.0 | 2.3 | 1.27 |
| Dave Williams* | Tor | sp | 27 | 3 | 2 | 2 | 6 | 4 | 2 | 4 | 7 | 15.7 | 3.6 | 20.0 | 3.6 | 1.9 | 1.0 | 2.14 |
| Jerome Williams | Mtl | mr | 24 | 2 | 0 | 0 | 3 | 1 | 1 | 0 | 4 | 15.3 | 8.8 | 24.7 | 4.3 | 2.2 | 0.5 | 2.67 |
| Dontrelle Willis* | Was | sp | 24 | 3 | 3 | 3 | 17 | 5 | 2 | 2 | 3 | 9.5 | 3.3 | 13.5 | 7.0 | 0.5 | 2.1 | 1.42 |
| C.J. Wilson* | Min | mr | 25 | 2 | 0 | 1 | 4 | 1 | 0 | 0 | 0 | 10.2 | 3.7 | 15.2 | 11.8 | 2.2 | 3.2 | 1.55 |
| Matt Wise | ChW | mr | 30 | 2 | 1 | 0 | 3 | 0 | 0 | 0 | 2 | 10.8 | 2.7 | 14.1 | 5.6 | 1.2 | 2.1 | 1.50 |
| Kerry Wood | Mtl | sp | 29 | 11 | 0 | 0 | 8 | 1 | 0 | 0 | 1 | 9.2 | 6.6 | 17.1 | 5.2 | 2.4 | 0.8 | 1.75 |
| Mike Wood | Mtl | mr | 26 | 3 | 3 | 5 | 18 | 10 | 0 | 6 | 7 | 12.8 | 2.2 | 15.8 | 3.8 | 1.2 | 1.8 | 1.66 |
| Jaret Wright | Det | sp | 30 | 2 | 5 | 3 | 6 | 5 | 0 | 3 | 5 | 9.8 | 4.2 | 14.3 | 5.1 | 0.5 | 1.2 | 1.55 |
| Tyler Yates | Tor | mr | 28 | 3 | 1 | 5 | 2 | 1 | 0 | 0 | 3 | 10.3 | 5.0 | 15.5 | 8.6 | 1.7 | 1.7 | 1.70 |
| Shane Youman* | Min | sp | 26 | 2 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 4.2 | 5.4 | 9.8 | 3.1 | 0.6 | 0.6 | 1.07 |
| Victor Zambrano | Det | sp | 30 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 11.9 | 7.1 | 19.1 | 7.1 | 0.8 | 1.0 | 2.12 |
| Barry Zito* | ChW | sp | 28 | 4 | 4 | 2 | 10 | 4 | 5 | 4 | 6 | 7.7 | 3.5 | 11.7 | 6.5 | 0.9 | 1.8 | 1.25 |
| Joel Zumaya | KCR | mr | 21 | 1 | 2 | 1 | 2 | 4 | 0 | 1 | 4 | 6.5 | 4.5 | 11.2 | 10.3 | 1.0 | 2.3 | 1.22 |
| Analytical |
| Name | Team | P | Age | OPS | BIP | BABIP | TBW | TBW/BF | TBWH | TBWH/BF | RC | RC27 | RCERA | CERA |
| Jeremy Accardo | ChW | mr | 24 | .772 | 182 | .335 | 119 | .467 | 120 | .471 | 34.4 | 5.3 | 4.83 | 4.69 |
| Jeremy Affeldt* | Bos | mr | 27 | .787 | 269 | .253 | 179 | .488 | 183 | .499 | 49.9 | 5.4 | 4.91 | 5.33 |
| Cha Seung Baek | NYY | sp | 26 | .675 | 107 | .196 | 73 | .440 | 76 | .458 | 15.9 | 3.4 | 3.11 | 3.21 |
| Danys Baez | Mtl | mr | 28 | .811 | 298 | .309 | 185 | .479 | 194 | .503 | 57.0 | 5.9 | 5.39 | 4.70 |
| Kevin Barry | Sea | mr | 27 | .936 | 14 | .286 | 17 | .630 | 17 | .630 | 5.6 | 8.9 | 8.48 | 8.08 |
| Miguel Batista | Sea | sp | 35 | .791 | 536 | .302 | 335 | .480 | 338 | .484 | 93.6 | 5.3 | 4.83 | 5.20 |
| Rick Bauer | Sea | mr | 29 | .621 | 273 | .242 | 132 | .369 | 138 | .385 | 27.2 | 2.7 | 2.43 | 2.73 |
| Jonah Bayliss | ChW | mr | 25 | .250 | 3 | .000 | 1 | .250 | 1 | .250 | 0.1 | 0.6 | 0.53 | 0.94 |
| Josh Beckett | KCR | sp | 26 | .721 | 610 | .230 | 414 | .471 | 421 | .479 | 95.6 | 3.9 | 3.56 | 3.39 |
| Joe Beimel* | Det | mr | 29 | .593 | 140 | .229 | 58 | .339 | 61 | .357 | 13.8 | 2.9 | 2.60 | 2.15 |
| Armando Benitez | ChW | cl | 33 | 1.032 | 73 | .329 | 74 | .643 | 75 | .652 | 25.4 | 9.8 | 9.37 | 9.90 |
| Joaquin Benoit | Tor | mr | 28 | .630 | 353 | .292 | 223 | .387 | 227 | .394 | 53.7 | 3.5 | 3.17 | 3.12 |
| Kris Benson | ChW | sp | 31 | .829 | 694 | .269 | 471 | .522 | 480 | .532 | 130.0 | 5.5 | 5.04 | 5.13 |
| Jason Bergmann | KCR | mr | 24 | .778 | 2 | .500 | 4 | .444 | 5 | .556 | 1.2 | 6.7 | 6.00 | 6.15 |
| Adam Bernero | Oak | sp | 29 | .722 | 39 | .282 | 26 | .473 | 26 | .473 | 6.0 | 3.9 | 3.47 | 2.82 |
| Rafael Betancourt | Oak | mr | 31 | .481 | 212 | .231 | 73 | .274 | 74 | .278 | 15.1 | 1.9 | 1.76 | 1.38 |
| Jeremy Bonderman | Oak | sp | 23 | .698 | 702 | .318 | 435 | .427 | 439 | .431 | 111.7 | 4.1 | 3.73 | 3.30 |
| Joe Borowski | KCR | cl | 35 | .696 | 259 | .313 | 175 | .424 | 179 | .433 | 46.7 | 4.3 | 4.01 | 3.73 |
| Chad Bradford | Bos | mr | 31 | .653 | 274 | .318 | 138 | .383 | 138 | .383 | 35.7 | 3.7 | 3.40 | 3.24 |
| Bill Bray* | Bos | mr | 23 | .776 | 75 | .307 | 51 | .481 | 51 | .481 | 12.8 | 4.7 | 4.15 | 4.61 |
| Craig Breslow* | Bal | mr | 25 | 1.045 | 18 | .389 | 17 | .607 | 18 | .643 | 6.2 | 11.1 | 9.38 | 11.40 |
| Chris Britton | Cle | mr | 23 | .637 | 145 | .262 | 75 | .383 | 77 | .393 | 19.6 | 3.8 | 3.43 | 2.78 |
| Doug Brocail | KCR | mr | 39 | .621 | 138 | .297 | 72 | .377 | 72 | .377 | 17.9 | 3.5 | 3.20 | 2.68 |
| Brian Bruney | Cle | mr | 24 | .598 | 65 | .231 | 41 | .387 | 42 | .396 | 7.6 | 2.6 | 2.41 | 2.70 |
| Taylor Buchholz | ChW | sp | 24 | .807 | 303 | .251 | 215 | .527 | 217 | .532 | 55.9 | 5.1 | 4.62 | 4.14 |
| Paul Byrd | Tor | sp | 35 | .833 | 687 | .317 | 423 | .500 | 429 | .507 | 131.1 | 6.2 | 5.72 | 5.57 |
| Daniel Cabrera | Cle | sp | 25 | .803 | 436 | .356 | 380 | .495 | 388 | .505 | 109.8 | 6.0 | 5.41 | 5.58 |
| Matt Cain | NYY | sp | 21 | .708 | 527 | .294 | 370 | .444 | 373 | .448 | 97.6 | 4.6 | 4.15 | 3.87 |
| Kiko Calero | Bal | mr | 31 | .734 | 266 | .338 | 207 | .457 | 208 | .459 | 54.1 | 4.7 | 4.19 | 4.36 |
| Shawn Camp | Oak | mr | 30 | .849 | 143 | .364 | 92 | .492 | 97 | .519 | 29.3 | 6.3 | 5.65 | 5.28 |
| Matt Capps | Sea | mr | 22 | .713 | 225 | .293 | 139 | .436 | 142 | .445 | 34.1 | 3.9 | 3.55 | 3.54 |
| Chris Capuano* | NYY | sp | 27 | .866 | 678 | .345 | 490 | .536 | 494 | .540 | 143.0 | 6.1 | 5.57 | 5.56 |
| Chris Carpenter | Tex | sp | 31 | .704 | 676 | .306 | 393 | .422 | 403 | .432 | 104.6 | 4.2 | 3.81 | 3.59 |
| Hector Carrasco | Min | mr | 36 | .628 | 392 | .222 | 229 | .403 | 232 | .408 | 48.9 | 3.1 | 2.81 | 2.74 |
| Fabio Castro* | Tor | mr | 21 | .519 | 21 | .238 | 8 | .286 | 9 | .321 | 1.9 | 2.4 | 2.18 | 1.62 |
| Gustavo Chacin* | Bal | sp | 25 | .862 | 347 | .291 | 259 | .541 | 265 | .553 | 75.3 | 6.2 | 5.58 | 5.48 |
| Shawn Chacon | Det | sp | 28 | .954 | 336 | .315 | 288 | .595 | 296 | .612 | 94.2 | 8.4 | 7.51 | 7.47 |
| Bruce Chen* | Cle | mr | 29 | .859 | 251 | .367 | 179 | .510 | 180 | .513 | 59.3 | 7.2 | 6.55 | 6.87 |
| Vinnie Chulk | Tex | mr | 27 | .779 | 224 | .335 | 151 | .467 | 153 | .474 | 46.6 | 5.9 | 5.29 | 4.98 |
| Brandon Claussen* | LAA | sp | 27 | .837 | 280 | .350 | 196 | .491 | 205 | .514 | 65.4 | 7.0 | 6.23 | 6.20 |
| Bartolo Colon | Sea | sp | 33 | .837 | 285 | .284 | 200 | .532 | 204 | .543 | 55.1 | 5.6 | 5.04 | 4.61 |
| Clay Condrey | Bos | mr | 30 | .706 | 29 | .241 | 15 | .441 | 15 | .441 | 3.1 | 3.1 | 2.78 | 3.39 |
| Tim Corcoran | Tex | sp | 28 | .746 | 478 | .264 | 328 | .478 | 332 | .484 | 80.6 | 4.5 | 4.10 | 4.10 |
| Francisco Cordero | Tex | cl | 31 | .766 | 258 | .310 | 175 | .463 | 177 | .468 | 50.7 | 5.5 | 4.93 | 4.81 |
| Lance Cormier | Oak | mr | 25 | .949 | 243 | .379 | 192 | .573 | 194 | .579 | 63.1 | 7.9 | 7.10 | 7.77 |
| Manuel Corpas | Mtl | mr | 23 | .885 | 108 | .361 | 83 | .542 | 87 | .569 | 25.4 | 6.6 | 5.81 | 4.92 |
| Juan Cruz | Min | mr | 27 | .676 | 400 | .287 | 243 | .400 | 256 | .422 | 64.3 | 4.1 | 3.75 | 3.71 |
| Jason Davis | KCR | mr | 26 | .548 | 32 | .156 | 14 | .326 | 15 | .349 | 2.7 | 2.1 | 1.88 | 1.67 |
| Zach Day | Bal | sp | 28 | .963 | 67 | .418 | 40 | .519 | 42 | .545 | 16.6 | 10.2 | 9.19 | 9.64 |
| Manny Delcarmen | Cle | mr | 24 | .694 | 184 | .299 | 106 | .412 | 107 | .416 | 26.1 | 3.8 | 3.36 | 3.57 |
| Ryan Dempster | LAA | cl | 29 | .539 | 187 | .235 | 92 | .331 | 94 | .338 | 19.7 | 2.7 | 2.41 | 2.33 |
| Joey Devine | Bos | mr | 22 | .892 | 8 | .125 | 8 | .500 | 10 | .625 | 2.4 | 6.4 | 5.74 | 8.27 |
| Scott Downs* | LAA | mr | 30 | .684 | 154 | .260 | 99 | .427 | 103 | .444 | 24.5 | 4.1 | 3.68 | 3.41 |
| Brandon Duckworth | Cle | sp | 30 | .803 | 165 | .339 | 113 | .485 | 114 | .489 | 34.3 | 6.1 | 5.71 | 5.57 |
| Zach Duke* | Tor | sp | 23 | .901 | 675 | .357 | 485 | .544 | 491 | .550 | 157.6 | 7.5 | 6.78 | 6.57 |
| Adam Eaton | LAA | sp | 28 | .865 | 284 | .299 | 211 | .536 | 216 | .548 | 64.3 | 6.6 | 5.92 | 5.80 |
| Joey Eischen* | Mtl | mr | 36 | 1.002 | 68 | .456 | 74 | .607 | 75 | .615 | 27.3 | 11.9 | 10.70 | 11.90 |
| Kelvim Escobar | Min | sp | 30 | .729 | 667 | .307 | 405 | .438 | 414 | .448 | 113.1 | 4.7 | 4.26 | 4.06 |
| Shawn Estes* | Oak | sp | 33 | .714 | 90 | .333 | 44 | .396 | 45 | .405 | 12.2 | 4.3 | 3.95 | 4.51 |
| Seth Etherton | ChW | sp | 29 | 1.186 | 40 | .450 | 42 | .724 | 42 | .724 | 18.0 | 15.7 | 15.06 | 14.24 |
| Dana Eveland* | Cle | sp | 22 | .946 | 124 | .355 | 120 | .566 | 129 | .608 | 39.9 | 8.0 | 7.29 | 7.90 |
| Willie Eyre | NYY | mr | 27 | .727 | 321 | .234 | 185 | .447 | 193 | .466 | 46.6 | 4.2 | 3.75 | 3.49 |
| Kyle Farnsworth | Det | mr | 30 | .687 | 164 | .317 | 107 | .423 | 107 | .423 | 27.2 | 4.1 | 3.69 | 3.88 |
| Ryan Feierabend* | Det | sp | 20 | .666 | 68 | .206 | 46 | .451 | 46 | .451 | 8.7 | 3.0 | 2.71 | 2.81 |
| Pedro Feliciano* | NYY | mr | 29 | .676 | 179 | .318 | 106 | .405 | 107 | .408 | 28.0 | 4.2 | 3.76 | 3.83 |
| Ron Flores* | KCR | mr | 26 | .656 | 85 | .188 | 53 | .438 | 53 | .438 | 11.8 | 3.5 | 3.19 | 2.61 |
| Casey Fossum* | KCR | sp | 28 | .820 | 387 | .297 | 280 | .511 | 287 | .524 | 82.8 | 6.0 | 5.45 | 5.41 |
| Keith Foulke | Oak | mr | 33 | .678 | 166 | .259 | 93 | .408 | 99 | .434 | 24.0 | 3.9 | 3.43 | 2.83 |
| Jeff Francis* | Bos | sp | 25 | .711 | 777 | .264 | 455 | .435 | 470 | .449 | 113.4 | 4.0 | 3.63 | 3.50 |
| Ryan Franklin | Tex | mr | 33 | .833 | 273 | .297 | 183 | .515 | 185 | .521 | 50.6 | 5.6 | 5.12 | 5.32 |
| Brian Fuentes* | Bal | cl | 30 | .731 | 251 | .291 | 190 | .447 | 198 | .466 | 49.9 | 4.6 | 4.07 | 4.04 |
| Aaron Fultz* | Cle | mr | 32 | .748 | 176 | .341 | 119 | .456 | 121 | .464 | 33.7 | 5.1 | 4.55 | 4.13 |
| Kason Gabbard* | Tor | sp | 24 | .754 | 123 | .285 | 80 | .468 | 80 | .468 | 21.2 | 5.2 | 4.64 | 5.45 |
| Jon Garland | Mtl | sp | 26 | .818 | 756 | .320 | 478 | .497 | 487 | .506 | 139.9 | 5.6 | 5.15 | 4.83 |
| Matt Garza | Bal | sp | 22 | 1.000 | 119 | .403 | 99 | .607 | 99 | .607 | 36.2 | 10.0 | 9.17 | 8.45 |
| Geoff Geary | LAA | mr | 29 | .706 | 338 | .331 | 179 | .402 | 185 | .416 | 48.6 | 4.1 | 3.73 | 3.84 |
| Jimmy Gobble* | Cle | mr | 24 | .800 | 307 | .306 | 242 | .513 | 243 | .515 | 66.8 | 5.5 | 5.02 | 4.68 |
| Enrique Gonzalez | KCR | sp | 23 | .792 | 187 | .289 | 121 | .480 | 125 | .496 | 34.5 | 5.5 | 5.05 | 5.41 |
| Geremi Gonzalez | Oak | mr | 31 | 1.061 | 175 | .400 | 169 | .660 | 170 | .664 | 65.1 | 11.6 | 10.40 | 9.90 |
| Tom Gordon | Bal | cl | 38 | .733 | 259 | .297 | 180 | .456 | 181 | .458 | 47.2 | 4.5 | 4.03 | 3.83 |
| Tom Gorzelanny* | Sea | sp | 23 | .671 | 269 | .249 | 169 | .421 | 173 | .431 | 40.5 | 3.9 | 3.49 | 3.44 |
| John Grabow* | KCR | mr | 27 | .693 | 174 | .322 | 119 | .425 | 122 | .436 | 31.1 | 4.3 | 3.93 | 3.78 |
| Zack Greinke | Bos | mr | 22 | .708 | 16 | .188 | 9 | .474 | 9 | .474 | 2.3 | 4.5 | 4.01 | 3.23 |
| Eddie Guardado* | Mtl | cl | 35 | 1.069 | 151 | .371 | 178 | .690 | 181 | .702 | 63.3 | 10.9 | 9.73 | 9.20 |
| Charlie Haeger | Cle | mr | 22 | .590 | 132 | .242 | 85 | .383 | 85 | .383 | 18.3 | 3.3 | 3.00 | 3.49 |
| Jason Hammel | ChW | sp | 23 | 1.002 | 141 | .376 | 128 | .615 | 130 | .625 | 45.8 | 10.3 | 9.50 | 9.80 |
| Chris Hammond* | Tor | mr | 40 | .841 | 20 | .250 | 16 | .571 | 16 | .571 | 3.8 | 4.9 | 4.41 | 4.31 |
| Josh Hancock | NYY | mr | 28 | .759 | 228 | .272 | 142 | .472 | 145 | .482 | 36.6 | 4.6 | 4.16 | 3.75 |
| Aaron Harang | Was | sp | 28 | .891 | 327 | .385 | 258 | .538 | 264 | .550 | 82.9 | 7.0 | 6.40 | 6.31 |
| Travis Harper | LAA | mr | 30 | 1.199 | 107 | .486 | 106 | .702 | 109 | .722 | 46.3 | 15.6 | 14.07 | 14.35 |
| Chad Harville | Det | mr | 29 | .773 | 107 | .271 | 81 | .491 | 81 | .491 | 21.3 | 5.2 | 4.70 | 5.32 |
| LaTroy Hawkins | Cle | mr | 33 | .747 | 231 | .329 | 126 | .438 | 127 | .441 | 37.7 | 5.2 | 4.72 | 4.58 |
| Aaron Heilman | Oak | mr | 27 | .712 | 128 | .289 | 87 | .444 | 88 | .449 | 23.2 | 4.6 | 4.05 | 3.61 |
| Rick Helling | Bos | mr | 35 | .880 | 74 | .216 | 72 | .600 | 73 | .608 | 19.6 | 6.2 | 5.35 | 4.42 |
| Mark Hendrickson* | LAA | sp | 32 | .725 | 622 | .309 | 360 | .427 | 366 | .434 | 100.5 | 4.6 | 4.21 | 4.35 |
| Sean Henn* | Tex | mr | 25 | .737 | 22 | .364 | 13 | .433 | 13 | .433 | 3.8 | 5.1 | 4.58 | 4.69 |
| Clay Hensley | Bal | sp | 26 | .770 | 668 | .308 | 421 | .466 | 426 | .472 | 112.0 | 4.8 | 4.37 | 4.60 |
| Felix Hernandez | Min | sp | 20 | .674 | 624 | .301 | 364 | .408 | 368 | .412 | 89.6 | 3.7 | 3.33 | 3.35 |
| Livan Hernandez | Was | sp | 31 | .780 | 752 | .291 | 454 | .475 | 458 | .480 | 129.7 | 5.3 | 4.82 | 4.80 |
| Orlando Hernandez | Sea | sp | 36 | .787 | 512 | .291 | 409 | .502 | 413 | .507 | 110.4 | 5.3 | 4.81 | 4.67 |
| Roberto Hernandez | Tor | mr | 41 | .788 | 344 | .305 | 242 | .490 | 243 | .492 | 67.5 | 5.5 | 4.96 | 4.96 |
| Runelvys Hernandez | ChW | sp | 28 | .980 | 499 | .339 | 387 | .591 | 395 | .603 | 130.7 | 8.5 | 7.82 | 8.70 |
| Jason Hirsh | Tex | sp | 24 | .857 | 311 | .264 | 247 | .536 | 255 | .553 | 77.1 | 6.9 | 6.35 | 6.14 |
| J.P. Howell* | Bos | sp | 23 | .688 | 166 | .337 | 98 | .394 | 103 | .414 | 26.8 | 4.2 | 3.72 | 3.90 |
| Tim Hudson | Det | sp | 30 | .836 | 621 | .324 | 426 | .510 | 432 | .517 | 129.8 | 6.2 | 5.58 | 5.20 |
| Jason Isringhausen | Bos | cl | 33 | .515 | 156 | .186 | 86 | .340 | 86 | .340 | 17.1 | 2.4 | 2.24 | 2.13 |
| Edwin Jackson | Min | mr | 22 | .761 | 138 | .304 | 105 | .471 | 108 | .484 | 27.9 | 5.2 | 4.61 | 5.21 |
| Zach Jackson* | Tex | sp | 23 | .813 | 121 | .256 | 84 | .509 | 86 | .521 | 24.7 | 6.2 | 5.83 | 6.00 |
| Chuck James* | Bos | sp | 24 | .766 | 360 | .269 | 260 | .488 | 264 | .495 | 70.1 | 5.1 | 4.64 | 4.39 |
| Bobby Jenks | KCR | cl | 25 | .667 | 202 | .371 | 129 | .399 | 129 | .399 | 30.8 | 3.5 | 3.18 | 3.29 |
| Tyler Johnson* | Sea | mr | 25 | .801 | 158 | .304 | 144 | .509 | 147 | .519 | 39.5 | 6.0 | 5.48 | 6.10 |
| Todd Jones | Mtl | cl | 38 | .564 | 211 | .242 | 84 | .328 | 86 | .336 | 15.5 | 2.0 | 1.87 | 1.97 |
| Scott Kazmir* | Bos | sp | 22 | .691 | 441 | .324 | 300 | .425 | 305 | .432 | 76.1 | 4.1 | 3.69 | 3.29 |
| Randy Keisler* | Mtl | mr | 30 | 1.051 | 30 | .333 | 28 | .700 | 28 | .700 | 5.8 | 5.1 | 4.55 | 5.96 |
| Joe Kennedy* | Min | mr | 27 | .536 | 146 | .281 | 64 | .308 | 65 | .313 | 14.0 | 2.4 | 2.17 | 1.87 |
| Logan Kensing | Was | mr | 23 | .831 | 189 | .302 | 178 | .525 | 185 | .546 | 51.6 | 6.2 | 5.55 | 5.55 |
| Bobby Keppel | Bal | sp | 24 | .847 | 259 | .324 | 178 | .517 | 180 | .523 | 51.1 | 5.8 | 5.26 | 5.62 |
| Byung-Hyun Kim | Bos | sp | 27 | .817 | 555 | .344 | 396 | .491 | 404 | .501 | 114.8 | 5.8 | 5.21 | 5.73 |
| Dan Kolb | ChW | mr | 31 | .855 | 143 | .350 | 89 | .500 | 90 | .506 | 28.3 | 6.5 | 5.98 | 6.39 |
| Hong-Chih Kuo* | Bos | mr | 24 | .813 | 163 | .393 | 151 | .508 | 152 | .512 | 43.4 | 6.0 | 5.46 | 5.41 |
| John Lackey | Bal | sp | 27 | .709 | 803 | .310 | 480 | .425 | 490 | .434 | 130.7 | 4.4 | 3.98 | 3.82 |
| Brandon League | Min | mr | 23 | .577 | 239 | .297 | 98 | .317 | 100 | .324 | 23.1 | 2.7 | 2.40 | 2.47 |
| Brad Lidge | ChW | cl | 29 | .782 | 168 | .381 | 159 | .488 | 161 | .494 | 43.0 | 5.3 | 4.86 | 5.34 |
| Francisco Liriano* | Min | sp | 22 | .612 | 369 | .314 | 223 | .372 | 226 | .377 | 49.5 | 2.9 | 2.64 | 2.52 |
| Esteban Loaiza | LAA | sp | 34 | .787 | 507 | .339 | 315 | .469 | 320 | .477 | 93.3 | 5.4 | 4.99 | 4.67 |
| Kameron Loe | NYY | sp | 24 | .906 | 60 | .333 | 40 | .548 | 40 | .548 | 12.6 | 7.1 | 6.38 | 7.17 |
| Boone Logan* | ChW | mr | 21 | .756 | 48 | .333 | 33 | .434 | 35 | .461 | 9.1 | 4.6 | 4.41 | 4.93 |
| Javier Lopez* | Tex | mr | 28 | .929 | 5 | .600 | 4 | .500 | 4 | .500 | 1.9 | 12.8 | 11.48 | 12.64 |
| Rodrigo Lopez | NYY | sp | 30 | .780 | 585 | .308 | 385 | .477 | 390 | .483 | 111.3 | 5.5 | 4.97 | 4.80 |
| Mark Lowe | Bos | mr | 23 | .816 | 109 | .385 | 83 | .485 | 86 | .503 | 24.3 | 5.7 | 5.08 | 5.12 |
| Ruddy Lugo | Was | mr | 26 | .695 | 277 | .274 | 159 | .415 | 164 | .428 | 40.7 | 4.1 | 3.66 | 3.83 |
| Ryan Madson | NYY | mr | 25 | 1.019 | 234 | .410 | 185 | .591 | 191 | .610 | 70.5 | 10.2 | 9.02 | 9.05 |
| Carlos Marmol | Bal | sp | 23 | .878 | 238 | .256 | 216 | .568 | 218 | .574 | 66.5 | 7.6 | 6.88 | 6.85 |
| Mike Maroth* | Tor | sp | 28 | .876 | 413 | .329 | 273 | .535 | 276 | .541 | 76.4 | 5.8 | 5.29 | 5.62 |
| Damaso Marte* | Was | mr | 31 | .638 | 147 | .259 | 106 | .411 | 107 | .415 | 23.6 | 3.5 | 3.12 | 3.48 |
| Carlos Martinez | Mtl | mr | 24 | .576 | 96 | .281 | 50 | .350 | 50 | .350 | 12.0 | 3.1 | 2.86 | 2.55 |
| Tom Mastny | Tex | cl | 25 | 1.400 | 3 | .000 | 5 | 1.000 | 5 | 1.000 | 1.7 | 15.3 | 13.80 | 14.27 |
| Juan Mateo | KCR | sp | 23 | .848 | 65 | .385 | 52 | .510 | 53 | .520 | 16.1 | 6.5 | 5.84 | 5.63 |
| Dustin McGowan | Cle | mr | 24 | .861 | 167 | .389 | 127 | .506 | 128 | .510 | 41.8 | 7.7 | 6.86 | 7.57 |
| Marty McLeary | NYY | mr | 31 | .234 | 17 | .059 | 4 | .182 | 4 | .182 | 0.2 | 0.3 | 0.31 | 0.54 |
| Brian Meadows | Bal | mr | 30 | .909 | 74 | .311 | 61 | .598 | 61 | .598 | 17.7 | 6.7 | 6.07 | 5.87 |
| Gil Meche |   | sp | 27 | .810 | 513 | .314 | 382 | .499 | 392 | .512 | 107.8 | 5.5 | 5.06 | 5.16 |
| Brandon Medders | Mtl | mr | 26 | .733 | 400 | .298 | 237 | .436 | 244 | .449 | 64.1 | 4.6 | 4.16 | 4.24 |
| Jose Mesa | Bal | mr | 40 | .761 | 355 | .290 | 209 | .437 | 223 | .467 | 59.7 | 5.0 | 4.56 | 4.89 |
| Dan Miceli | Tor | mr | 35 | .652 | 63 | .238 | 40 | .412 | 41 | .423 | 9.4 | 3.6 | 3.20 | 2.94 |
| Trever Miller* | Det | mr | 33 | .668 | 157 | .325 | 102 | .400 | 107 | .420 | 26.3 | 3.8 | 3.44 | 3.14 |
| Eric Milton* | Cle | sp | 30 | .850 | 580 | .310 | 413 | .532 | 419 | .540 | 123.1 | 6.3 | 5.72 | 5.31 |
| Zach Miner | Det | sp | 24 | .780 | 257 | .319 | 164 | .473 | 164 | .473 | 46.6 | 5.3 | 4.74 | 4.64 |
| Brian Moehler | Sea | sp | 34 | .839 | 128 | .344 | 79 | .503 | 80 | .510 | 23.3 | 5.9 | 5.34 | 5.49 |
| Matt Morris | Mtl | sp | 31 | .817 | 394 | .315 | 246 | .487 | 249 | .493 | 76.9 | 6.1 | 5.63 | 5.20 |
| Jamie Moyer* | Tor | sp | 43 | .826 | 664 | .312 | 440 | .512 | 444 | .517 | 128.7 | 5.9 | 5.38 | 5.05 |
| Edward Mujica | Cle | mr | 22 | .925 | 66 | .394 | 43 | .512 | 46 | .548 | 16.0 | 8.0 | 7.34 | 7.47 |
| Mark Mulder* | Was | sp | 28 | 1.064 | 29 | .379 | 27 | .659 | 27 | .659 | 9.8 | 12.0 | 10.79 | 11.61 |
| Scott Munter | NYY | mr | 26 | .861 | 66 | .333 | 40 | .494 | 41 | .506 | 12.7 | 6.4 | 5.83 | 6.05 |
| Brett Myers | Oak | sp | 25 | .728 | 585 | .321 | 387 | .445 | 391 | .449 | 98.2 | 4.2 | 3.82 | 4.02 |
| Chris Narveson* | Min | mr | 24 | .690 | 63 | .270 | 53 | .465 | 54 | .474 | 12.4 | 4.1 | 3.71 | 2.46 |
| Joe Nathan | Was | cl | 31 | .322 | 202 | .178 | 74 | .205 | 74 | .205 | 8.4 | 0.7 | 0.66 | 0.60 |
| Joe Nelson | ChW | mr | 31 | .628 | 99 | .242 | 58 | .389 | 60 | .403 | 12.4 | 2.9 | 2.64 | 2.63 |
| Fernando Nieve | Bos | mr | 23 | .854 | 373 | .268 | 294 | .549 | 297 | .554 | 79.4 | 5.8 | 5.16 | 5.62 |
| Roberto Novoa | Sea | mr | 26 | .827 | 284 | .275 | 217 | .515 | 226 | .537 | 58.0 | 5.3 | 4.76 | 5.02 |
| Mike O'Connor* | KCR | sp | 25 | .809 | 268 | .306 | 179 | .494 | 183 | .506 | 53.2 | 6.0 | 5.44 | 5.47 |
| Ryan O'Malley* | Was | sp | 26 | .657 | 126 | .246 | 61 | .374 | 63 | .387 | 17.2 | 4.5 | 4.10 | 4.53 |
| Darren Oliver* |   | mr | 35 | .682 | 260 | .254 | 164 | .432 | 167 | .439 | 38.6 | 3.8 | 3.41 | 3.25 |
| Ramon Ortiz | NYY | sp | 33 | .920 | 563 | .353 | 398 | .542 | 411 | .560 | 134.6 | 7.7 | 6.99 | 7.21 |
| Russ Ortiz | Tor | mr | 32 | .952 | 168 | .387 | 144 | .583 | 145 | .587 | 49.2 | 8.9 | 7.92 | 7.81 |
| Vicente Padilla | KCR | sp | 28 | .707 | 534 | .285 | 325 | .416 | 345 | .441 | 88.8 | 4.4 | 3.91 | 3.87 |
| Jonathan Papelbon | Min | cl | 25 | .396 | 210 | .190 | 72 | .239 | 73 | .243 | 11.6 | 1.3 | 1.14 | 0.93 |
| Chan Ho Park | ChW | sp | 33 | .715 | 487 | .294 | 284 | .426 | 294 | .441 | 73.8 | 4.2 | 3.80 | 3.90 |
| Jake Peavy | ChW | sp | 25 | .765 | 559 | .340 | 412 | .469 | 417 | .475 | 113.8 | 5.0 | 4.47 | 4.31 |
| Tony Pena | Oak | mr | 24 | .717 | 114 | .298 | 67 | .447 | 67 | .447 | 15.5 | 3.7 | 3.34 | 2.95 |
| Joel Peralta | Tex | mr | 30 | .691 | 296 | .267 | 175 | .422 | 180 | .434 | 44.1 | 4.1 | 3.71 | 3.59 |
| Odalis Perez* | Min | sp | 29 | .774 | 555 | .308 | 335 | .461 | 343 | .472 | 102.9 | 5.6 | 5.11 | 4.60 |
| Oliver Perez* | LAA | sp | 24 | .869 | 232 | .319 | 201 | .536 | 204 | .544 | 59.9 | 6.9 | 6.19 | 7.25 |
| Joel Pineiro | Sea | sp | 27 | .880 | 396 | .290 | 284 | .548 | 291 | .562 | 88.6 | 6.9 | 6.24 | 5.87 |
| Mark Prior | KCR | sp | 25 | .477 | 33 | .182 | 13 | .277 | 15 | .319 | 2.6 | 2.2 | 1.89 | 2.42 |
| Scott Proctor | NYY | mr | 29 | .691 | 277 | .235 | 175 | .443 | 177 | .448 | 39.8 | 3.6 | 3.30 | 3.07 |
| Brad Radke | Was | sp | 33 | .967 | 241 | .373 | 182 | .597 | 182 | .597 | 62.5 | 8.7 | 7.75 | 7.62 |
| Horacio Ramirez* | Tex | sp | 26 | .797 | 478 | .305 | 299 | .472 | 310 | .490 | 90.4 | 5.8 | 5.27 | 5.55 |
| Chris Ray | Cle | cl | 24 | .540 | 144 | .188 | 71 | .338 | 75 | .357 | 15.2 | 2.6 | 2.38 | 2.00 |
| Mark Redman* | Mtl | sp | 32 | .807 | 629 | .302 | 387 | .489 | 393 | .496 | 112.4 | 5.6 | 5.14 | 5.10 |
| Chris Resop | Cle | mr | 23 | .936 | 177 | .362 | 125 | .566 | 126 | .570 | 37.6 | 7.0 | 6.44 | 6.81 |
| Anthony Reyes | KCR | sp | 24 | 1.068 | 153 | .320 | 154 | .670 | 161 | .700 | 53.7 | 10.1 | 9.19 | 9.08 |
| David Riske | ChW | mr | 29 | .879 | 66 | .333 | 52 | .542 | 52 | .542 | 16.9 | 7.5 | 6.83 | 6.72 |
| Mariano Rivera | Tor | cl | 36 | .624 | 329 | .301 | 146 | .344 | 153 | .360 | 36.2 | 3.1 | 2.80 | 2.80 |
| Francisco Rodriguez | Tor | cl | 24 | .654 | 260 | .304 | 185 | .416 | 187 | .420 | 43.0 | 3.5 | 3.17 | 2.70 |
| Kenny Rogers* | LAA | sp | 41 | .677 | 770 | .260 | 403 | .412 | 411 | .421 | 95.9 | 3.6 | 3.28 | 3.25 |
| Glendon Rusch* | LAA | mr | 31 | 1.095 | 114 | .421 | 116 | .674 | 117 | .680 | 42.4 | 11.0 | 9.81 | 10.30 |
| B.J. Ryan* | Was | cl | 30 | .317 | 180 | .156 | 67 | .210 | 67 | .210 | 7.1 | 0.7 | 0.64 | 0.73 |
| Kirk Saarloos | Bal | mr | 27 | .789 | 464 | .276 | 292 | .488 | 295 | .493 | 76.3 | 4.8 | 4.45 | 4.61 |
| C.C. Sabathia* |   | sp | 25 | .686 | 638 | .337 | 361 | .396 | 371 | .407 | 98.9 | 4.1 | 3.74 | 3.56 |
| Juan Salas | Oak | mr | 27 | 1.700 | 8 | .625 | 11 | 1.100 | 11 | 1.100 | 5.5 | 29.7 | 33.41 | 36.48 |
| Chris Sampson | NYY | mr | 28 | .578 | 67 | .224 | 26 | .325 | 28 | .350 | 5.6 | 2.5 | 2.21 | 2.43 |
| Anibal Sanchez | Was | sp | 22 | .631 | 415 | .236 | 218 | .389 | 222 | .396 | 49.4 | 3.3 | 2.95 | 3.15 |
| Duaner Sanchez | Mtl | mr | 26 | .709 | 193 | .301 | 129 | .434 | 132 | .444 | 32.6 | 4.2 | 3.80 | 3.99 |
| Johan Santana* | Sea | sp | 27 | .668 | 662 | .305 | 407 | .405 | 421 | .419 | 99.7 | 3.6 | 3.28 | 2.96 |
| Scott Sauerbeck* | ChW | mr | 34 | .870 | 50 | .320 | 40 | .460 | 48 | .552 | 14.7 | 7.9 | 7.00 | 8.16 |
| Joe Saunders* | Cle | sp | 25 | .668 | 375 | .288 | 192 | .396 | 193 | .398 | 45.4 | 3.4 | 3.15 | 3.46 |
| Scott Schoeneweis* | Tex | mr | 32 | .709 | 234 | .252 | 139 | .444 | 140 | .447 | 31.7 | 3.7 | 3.37 | 3.83 |
| Chris Schroder | Tex | mr | 27 | .694 | 12 | .250 | 10 | .400 | 12 | .480 | 2.8 | 5.1 | 4.59 | 4.27 |
| Rudy Seanez | Det | mr | 37 | .875 | 64 | .344 | 57 | .553 | 57 | .553 | 18.0 | 7.4 | 6.54 | 6.21 |
| Bobby Seay* | LAA | mr | 28 | 1.261 | 8 | .375 | 12 | .800 | 12 | .800 | 4.8 | 18.6 | 16.74 | 18.26 |
| Ben Sheets | Oak | sp | 27 | .689 | 456 | .318 | 283 | .421 | 289 | .429 | 72.2 | 3.9 | 3.53 | 3.07 |
| George Sherrill* | KCR | mr | 29 | .609 | 166 | .319 | 92 | .354 | 94 | .362 | 23.3 | 3.5 | 3.04 | 2.91 |
| Matt Smith* | Cle | mr | 27 | .547 | 60 | .233 | 33 | .344 | 34 | .354 | 6.7 | 2.5 | 2.18 | 1.91 |
| Kyle Snyder | Tex | sp | 28 | .894 | 323 | .387 | 249 | .540 | 252 | .547 | 82.1 | 7.4 | 6.61 | 6.42 |
| Rafael Soriano | Min | mr | 26 | .623 | 204 | .245 | 127 | .394 | 130 | .404 | 28.7 | 3.3 | 2.98 | 2.89 |
| Jeremy Sowers* | Det | sp | 23 | .707 | 370 | .246 | 196 | .433 | 199 | .439 | 49.4 | 4.0 | 3.61 | 3.45 |
| Brian Stokes | Oak | sp | 26 | .910 | 227 | .379 | 165 | .539 | 168 | .549 | 55.9 | 8.0 | 7.22 | 7.28 |
| Huston Street | NYY | cl | 22 | .586 | 189 | .280 | 96 | .345 | 98 | .353 | 22.9 | 3.0 | 2.71 | 2.33 |
| Jeff Suppan | Was | sp | 31 | .845 | 623 | .311 | 436 | .523 | 444 | .532 | 125.6 | 6.0 | 5.41 | 5.28 |
| Taylor Tankersley* | Det | mr | 23 | .704 | 107 | .327 | 82 | .436 | 84 | .447 | 20.8 | 4.4 | 3.95 | 4.39 |
| Jack Taschner* | NYY | mr | 28 | .000 | 2 | .000 | 0 | .000 | 0 | .000 | -0.0 | -0.0 | -0.00 | 0.00 |
| Ty Taubenheim | ChW | sp | 23 | .872 | 96 | .323 | 76 | .535 | 77 | .542 | 23.8 | 7.1 | 6.43 | 6.57 |
| Mike Timlin | Was | mr | 40 | .787 | 100 | .320 | 55 | .455 | 57 | .471 | 15.3 | 4.7 | 4.26 | 4.49 |
| Brett Tomko | NYY | mr | 33 | .783 | 501 | .287 | 316 | .477 | 325 | .491 | 91.8 | 5.4 | 4.90 | 4.42 |
| Salomon Torres | LAA | mr | 34 | .657 | 285 | .333 | 150 | .373 | 152 | .378 | 35.8 | 3.3 | 3.03 | 3.55 |
| Josh Towers | Tex | sp | 29 | 1.070 | 221 | .398 | 168 | .629 | 172 | .644 | 67.1 | 11.5 | 10.73 | 11.11 |
| Steve Trachsel | LAA | sp | 35 | .846 | 491 | .283 | 351 | .526 | 354 | .531 | 104.0 | 6.4 | 5.74 | 6.06 |
| Jose Veras | Oak | mr | 25 | .800 | 54 | .296 | 43 | .506 | 43 | .506 | 12.3 | 6.1 | 5.85 | 6.14 |
| Justin Verlander | Cle | sp | 23 | .733 | 646 | .302 | 390 | .437 | 400 | .448 | 103.9 | 4.5 | 4.08 | 4.39 |
| Ron Villone* | LAA | mr | 36 | .715 | 248 | .319 | 161 | .435 | 164 | .443 | 43.4 | 4.6 | 4.22 | 4.19 |
| Luis Vizcaino | Bos | mr | 31 | .741 | 203 | .286 | 149 | .478 | 150 | .481 | 36.1 | 4.2 | 3.83 | 3.44 |
| Ryan Vogelsong | Was | mr | 28 | .838 | 140 | .329 | 104 | .502 | 109 | .527 | 33.2 | 6.8 | 6.25 | 6.56 |
| Edinson Volquez | Mtl | sp | 22 | .846 | 218 | .307 | 139 | .509 | 141 | .516 | 44.5 | 6.8 | 6.14 | 6.40 |
| Billy Wagner* | Bos | cl | 34 | .691 | 203 | .374 | 151 | .419 | 152 | .422 | 39.6 | 4.2 | 3.85 | 3.70 |
| Ryan Wagner | Oak | mr | 23 | .653 | 65 | .323 | 29 | .367 | 29 | .367 | 8.0 | 3.8 | 3.52 | 3.68 |
| Tim Wakefield | Sea | sp | 39 | .725 | 620 | .240 | 376 | .450 | 389 | .466 | 98.8 | 4.4 | 4.01 | 3.87 |
| John Wasdin | Oak | sp | 33 | .835 | 152 | .243 | 103 | .493 | 113 | .541 | 32.0 | 6.2 | 5.60 | 5.24 |
| Jarrod Washburn* | Det | sp | 31 | .777 | 627 | .313 | 378 | .469 | 382 | .474 | 109.2 | 5.3 | 4.78 | 4.45 |
| David Weathers | Det | mr | 36 | .723 | 200 | .270 | 131 | .456 | 131 | .456 | 34.5 | 4.7 | 4.30 | 4.14 |
| Brandon Webb | Det | sp | 27 | .637 | 734 | .277 | 380 | .383 | 386 | .389 | 91.2 | 3.3 | 3.02 | 2.81 |
| David Wells* | Bal | sp | 43 | .912 | 398 | .359 | 269 | .551 | 271 | .555 | 84.6 | 7.0 | 6.39 | 6.70 |
| Kip Wells | Mtl | sp | 29 | .882 | 320 | .284 | 229 | .539 | 236 | .555 | 73.2 | 7.5 | 6.71 | 7.08 |
| Jake Westbrook | Tex | sp | 28 | .702 | 753 | .275 | 403 | .425 | 407 | .429 | 104.8 | 4.1 | 3.81 | 3.74 |
| Dave Williams* | Tor | sp | 27 | 1.061 | 326 | .380 | 259 | .627 | 265 | .642 | 99.1 | 10.9 | 9.95 | 10.04 |
| Jerome Williams | Mtl | mr | 24 | 1.158 | 177 | .379 | 183 | .709 | 186 | .721 | 71.4 | 14.0 | 12.58 | 12.90 |
| Dontrelle Willis* | Was | sp | 24 | .716 | 659 | .326 | 388 | .414 | 405 | .432 | 104.4 | 4.4 | 3.90 | 4.31 |
| C.J. Wilson* | Min | mr | 25 | .892 | 74 | .351 | 75 | .556 | 79 | .585 | 23.1 | 7.0 | 6.47 | 6.46 |
| Matt Wise | ChW | mr | 30 | .818 | 153 | .327 | 100 | .488 | 103 | .502 | 29.8 | 5.8 | 5.17 | 5.40 |
| Kerry Wood | Mtl | sp | 29 | .968 | 162 | .241 | 156 | .619 | 164 | .651 | 51.3 | 8.8 | 8.00 | 7.54 |
| Mike Wood | Mtl | mr | 26 | .887 | 663 | .339 | 423 | .515 | 441 | .536 | 142.9 | 7.3 | 6.59 | 6.52 |
| Jaret Wright | Det | sp | 30 | .738 | 549 | .310 | 322 | .438 | 328 | .446 | 88.9 | 4.9 | 4.37 | 4.64 |
| Tyler Yates | Tor | mr | 28 | .881 | 255 | .329 | 228 | .560 | 230 | .565 | 67.7 | 6.9 | 6.23 | 6.32 |
| Shane Youman* | Min | sp | 26 | .503 | 137 | .139 | 63 | .341 | 64 | .346 | 10.3 | 1.9 | 1.78 | 2.00 |
| Victor Zambrano | Det | sp | 30 | .867 | 35 | .400 | 28 | .519 | 28 | .519 | 8.4 | 6.9 | 6.00 | 7.80 |
| Barry Zito* | ChW | sp | 28 | .678 | 694 | .259 | 415 | .419 | 425 | .429 | 97.3 | 3.7 | 3.34 | 3.44 |
| Joel Zumaya | KCR | mr | 21 | .636 | 290 | .252 | 208 | .414 | 210 | .417 | 47.1 | 3.5 | 3.18 | 3.12 |
| Start |
| Name | Team | P | Age | GS | CG | CG% | SHO | QS | QS% | RS | RS/G | RL | RLS | RL% | NP/G | STR% |
| Jeremy Accardo | ChW | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 6 | .316 | 22.0 | .637 |
| Jeremy Affeldt* | Bos | mr | 27 | 11 | 0 | .000 | 0 | 3 | .273 | 79 | 7.2 | 19 | 3 | .158 | 47.2 | .587 |
| Cha Seung Baek | NYY | sp | 26 | 6 | 1 | .167 | 0 | 2 | .333 | 24 | 4.0 | 4 | 0 | .000 | 103.2 | .635 |
| Danys Baez | Mtl | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 4 | .308 | 23.6 | .643 |
| Kevin Barry | Sea | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 3 | .750 | 14.8 | .534 |
| Miguel Batista | Sea | sp | 35 | 25 | 3 | .120 | 0 | 11 | .440 | 141 | 5.6 | 16 | 7 | .438 | 96.3 | .590 |
| Rick Bauer | Sea | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 5 | .313 | 22.7 | .617 |
| Jonah Bayliss | ChW | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 18.0 | .500 |
| Josh Beckett | KCR | sp | 26 | 33 | 2 | .061 | 0 | 19 | .576 | 152 | 4.6 | 18 | 6 | .333 | 100.1 | .635 |
| Joe Beimel* | Det | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 2 | .167 | 18.2 | .656 |
| Armando Benitez | ChW | cl | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 3 | .300 | 24.2 | .578 |
| Joaquin Benoit | Tor | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 10 | .370 | 34.8 | .627 |
| Kris Benson | ChW | sp | 31 | 32 | 2 | .063 | 1 | 15 | .469 | 179 | 5.6 | 26 | 15 | .577 | 97.2 | .638 |
| Jason Bergmann | KCR | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 12.7 | .579 |
| Adam Bernero | Oak | sp | 29 | 3 | 0 | .000 | 0 | 1 | .333 | 6 | 2.0 | 2 | 2 | 1.000 | 61.7 | .676 |
| Rafael Betancourt | Oak | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 | 16.9 | .709 |
| Jeremy Bonderman | Oak | sp | 23 | 34 | 5 | .147 | 1 | 21 | .618 | 164 | 4.8 | 24 | 8 | .333 | 109.0 | .645 |
| Joe Borowski | KCR | cl | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 31 | 6 | .194 | 24.5 | .615 |
| Chad Bradford | Bos | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 4 | .125 | 21.2 | .673 |
| Bill Bray* | Bos | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 29.2 | .600 |
| Craig Breslow* | Bal | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 | 19.7 | .492 |
| Chris Britton | Cle | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 7 | .438 | 27.0 | .624 |
| Doug Brocail | KCR | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 4 | .500 | 22.7 | .653 |
| Brian Bruney | Cle | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 7 | .778 | 26.6 | .558 |
| Taylor Buchholz | ChW | sp | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 8 | .533 | 25.7 | .645 |
| Paul Byrd | Tor | sp | 35 | 32 | 4 | .125 | 3 | 13 | .406 | 153 | 4.8 | 31 | 15 | .484 | 78.5 | .655 |
| Daniel Cabrera | Cle | sp | 25 | 30 | 0 | .000 | 0 | 10 | .333 | 151 | 5.0 | 37 | 17 | .459 | 104.3 | .563 |
| Matt Cain | NYY | sp | 21 | 32 | 1 | .031 | 0 | 19 | .594 | 118 | 3.7 | 22 | 7 | .318 | 101.4 | .587 |
| Kiko Calero | Bal | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 38 | 10 | .263 | 23.2 | .602 |
| Shawn Camp | Oak | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 2 | .167 | 23.1 | .657 |
| Matt Capps | Sea | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 2 | .250 | 17.6 | .686 |
| Chris Capuano* | NYY | sp | 27 | 34 | 4 | .118 | 1 | 11 | .324 | 167 | 4.9 | 26 | 9 | .346 | 92.5 | .660 |
| Chris Carpenter | Tex | sp | 31 | 32 | 5 | .156 | 0 | 20 | .625 | 197 | 6.2 | 23 | 5 | .217 | 104.0 | .645 |
| Hector Carrasco | Min | mr | 36 | 7 | 0 | .000 | 0 | 5 | .714 | 25 | 3.6 | 20 | 6 | .300 | 35.7 | .642 |
| Fabio Castro* | Tor | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 20.8 | .587 |
| Gustavo Chacin* | Bal | sp | 25 | 18 | 1 | .056 | 0 | 4 | .222 | 93 | 5.2 | 13 | 8 | .615 | 95.7 | .628 |
| Shawn Chacon | Det | sp | 28 | 2 | 0 | .000 | 0 | 1 | .500 | 13 | 6.5 | 22 | 3 | .136 | 42.6 | .593 |
| Bruce Chen* | Cle | mr | 29 | 15 | 0 | .000 | 0 | 6 | .400 | 49 | 3.3 | 16 | 5 | .313 | 82.8 | .622 |
| Vinnie Chulk | Tex | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 9 | .429 | 26.4 | .611 |
| Brandon Claussen* | LAA | sp | 27 | 16 | 0 | .000 | 0 | 5 | .313 | 84 | 5.3 | 18 | 6 | .333 | 91.6 | .608 |
| Bartolo Colon | Sea | sp | 33 | 14 | 4 | .286 | 1 | 7 | .500 | 50 | 3.6 | 11 | 3 | .273 | 92.0 | .658 |
| Clay Condrey | Bos | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 24.8 | .710 |
| Tim Corcoran | Tex | sp | 28 | 26 | 3 | .115 | 0 | 14 | .538 | 159 | 6.1 | 18 | 4 | .222 | 98.1 | .580 |
| Francisco Cordero | Tex | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 | 18.5 | .626 |
| Lance Cormier | Oak | mr | 25 | 11 | 0 | .000 | 0 | 2 | .182 | 54 | 4.9 | 15 | 7 | .467 | 68.0 | .606 |
| Manuel Corpas | Mtl | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 2 | .250 | 24.4 | .638 |
| Juan Cruz | Min | mr | 27 | 23 | 0 | .000 | 0 | 9 | .391 | 116 | 5.0 | 25 | 6 | .240 | 99.8 | .588 |
| Jason Davis | KCR | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 18.3 | .753 |
| Zach Day | Bal | sp | 28 | 2 | 0 | .000 | 0 | 0 | .000 | 12 | 6.0 | 4 | 2 | .500 | 48.0 | .579 |
| Manny Delcarmen | Cle | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 7 | .280 | 20.3 | .640 |
| Ryan Dempster | LAA | cl | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 | 17.6 | .579 |
| Joey Devine | Bos | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 29.0 | .534 |
| Scott Downs* | LAA | mr | 30 | 3 | 0 | .000 | 0 | 3 | 1.000 | 8 | 2.7 | 11 | 5 | .455 | 34.2 | .602 |
| Brandon Duckworth | Cle | sp | 30 | 4 | 0 | .000 | 0 | 0 | .000 | 26 | 6.5 | 13 | 6 | .462 | 46.5 | .601 |
| Zach Duke* | Tor | sp | 23 | 34 | 0 | .000 | 0 | 8 | .235 | 199 | 5.9 | 28 | 9 | .321 | 93.0 | .609 |
| Adam Eaton | LAA | sp | 28 | 16 | 0 | .000 | 0 | 6 | .375 | 65 | 4.1 | 14 | 3 | .214 | 89.4 | .637 |
| Joey Eischen* | Mtl | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 13 | .619 | 26.8 | .506 |
| Kelvim Escobar | Min | sp | 30 | 32 | 4 | .125 | 1 | 20 | .625 | 153 | 4.8 | 33 | 11 | .333 | 103.4 | .644 |
| Shawn Estes* | Oak | sp | 33 | 5 | 0 | .000 | 0 | 3 | .600 | 25 | 5.0 | 2 | 1 | .500 | 85.4 | .597 |
| Seth Etherton | ChW | sp | 29 | 3 | 0 | .000 | 0 | 0 | .000 | 15 | 5.0 | 3 | 3 | 1.000 | 65.7 | .589 |
| Dana Eveland* | Cle | sp | 22 | 9 | 0 | .000 | 0 | 0 | .000 | 33 | 3.7 | 11 | 5 | .455 | 76.5 | .614 |
| Willie Eyre | NYY | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 1 | .091 | 30.6 | .627 |
| Kyle Farnsworth | Det | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 3 | .429 | 19.6 | .644 |
| Ryan Feierabend* | Det | sp | 20 | 4 | 0 | .000 | 0 | 3 | .750 | 10 | 2.5 | 1 | 0 | .000 | 99.8 | .604 |
| Pedro Feliciano* | NYY | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 6 | .240 | 20.7 | .615 |
| Ron Flores* | KCR | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 27.6 | .633 |
| Casey Fossum* | KCR | sp | 28 | 22 | 0 | .000 | 0 | 9 | .409 | 115 | 5.2 | 16 | 7 | .438 | 93.2 | .616 |
| Keith Foulke | Oak | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 | 16.6 | .690 |
| Jeff Francis* | Bos | sp | 25 | 35 | 7 | .200 | 2 | 25 | .714 | 185 | 5.3 | 22 | 7 | .318 | 104.1 | .614 |
| Ryan Franklin | Tex | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 13 | .464 | 24.9 | .606 |
| Brian Fuentes* | Bal | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 2 | .118 | 22.5 | .603 |
| Aaron Fultz* | Cle | mr | 32 | 4 | 0 | .000 | 0 | 2 | .500 | 23 | 5.8 | 28 | 8 | .286 | 22.6 | .636 |
| Kason Gabbard* | Tor | sp | 24 | 7 | 1 | .143 | 0 | 2 | .286 | 49 | 7.0 | 5 | 2 | .400 | 91.3 | .537 |
| Jon Garland | Mtl | sp | 26 | 34 | 3 | .088 | 0 | 15 | .441 | 103 | 3.0 | 20 | 9 | .450 | 95.9 | .662 |
| Matt Garza | Bal | sp | 22 | 6 | 0 | .000 | 0 | 1 | .167 | 19 | 3.2 | 4 | 2 | .500 | 84.6 | .611 |
| Geoff Geary | LAA | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 6 | .429 | 24.9 | .650 |
| Jimmy Gobble* | Cle | mr | 24 | 10 | 0 | .000 | 0 | 5 | .500 | 60 | 6.0 | 19 | 6 | .316 | 43.3 | .627 |
| Enrique Gonzalez | KCR | sp | 23 | 11 | 0 | .000 | 0 | 3 | .273 | 68 | 6.2 | 15 | 9 | .600 | 76.0 | .588 |
| Geremi Gonzalez | Oak | mr | 31 | 4 | 0 | .000 | 0 | 1 | .250 | 20 | 5.0 | 6 | 3 | .500 | 46.6 | .614 |
| Tom Gordon | Bal | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 3 | .150 | 23.7 | .633 |
| Tom Gorzelanny* | Sea | sp | 23 | 15 | 0 | .000 | 0 | 10 | .667 | 92 | 6.1 | 12 | 4 | .333 | 101.6 | .572 |
| John Grabow* | KCR | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 2 | .125 | 26.8 | .613 |
| Zack Greinke | Bos | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 20.7 | .629 |
| Eddie Guardado* | Mtl | cl | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 7 | .333 | 21.6 | .638 |
| Charlie Haeger | Cle | mr | 22 | 4 | 0 | .000 | 0 | 3 | .750 | 27 | 6.8 | 10 | 3 | .300 | 70.1 | .528 |
| Jason Hammel | ChW | sp | 23 | 10 | 0 | .000 | 0 | 1 | .100 | 52 | 5.2 | 11 | 4 | .364 | 78.6 | .570 |
| Chris Hammond* | Tor | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 47.5 | .621 |
| Josh Hancock | NYY | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 3 | .300 | 27.9 | .632 |
| Aaron Harang | Was | sp | 28 | 18 | 2 | .111 | 1 | 6 | .333 | 73 | 4.1 | 14 | 5 | .357 | 100.3 | .630 |
| Travis Harper | LAA | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 2 | .182 | 31.4 | .604 |
| Chad Harville | Det | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 37.2 | .570 |
| LaTroy Hawkins | Cle | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 3 | .143 | 16.4 | .661 |
| Aaron Heilman | Oak | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 | 23.6 | .618 |
| Rick Helling | Bos | mr | 35 | 3 | 0 | .000 | 0 | 0 | .000 | 10 | 3.3 | 5 | 2 | .400 | 30.3 | .652 |
| Mark Hendrickson* | LAA | sp | 32 | 27 | 0 | .000 | 0 | 13 | .481 | 133 | 4.9 | 19 | 9 | .474 | 83.7 | .604 |
| Sean Henn* | Tex | mr | 25 | 1 | 0 | .000 | 0 | 0 | .000 | 2 | 2.0 | 1 | 0 | .000 | 60.0 | .600 |
| Clay Hensley | Bal | sp | 26 | 34 | 5 | .147 | 2 | 18 | .529 | 188 | 5.5 | 25 | 9 | .360 | 97.8 | .601 |
| Felix Hernandez | Min | sp | 20 | 32 | 2 | .063 | 1 | 21 | .656 | 159 | 5.0 | 18 | 4 | .222 | 104.8 | .637 |
| Livan Hernandez | Was | sp | 31 | 34 | 1 | .029 | 0 | 16 | .471 | 195 | 5.7 | 27 | 7 | .259 | 99.8 | .617 |
| Orlando Hernandez | Sea | sp | 36 | 31 | 0 | .000 | 0 | 16 | .516 | 124 | 4.0 | 19 | 4 | .211 | 102.4 | .605 |
| Roberto Hernandez | Tor | mr | 41 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 9 | .375 | 28.4 | .618 |
| Runelvys Hernandez | ChW | sp | 28 | 30 | 0 | .000 | 0 | 6 | .200 | 175 | 5.8 | 34 | 14 | .412 | 78.1 | .600 |
| Jason Hirsh | Tex | sp | 24 | 19 | 0 | .000 | 0 | 7 | .368 | 96 | 5.1 | 13 | 6 | .462 | 88.5 | .587 |
| J.P. Howell* | Bos | sp | 23 | 11 | 0 | .000 | 0 | 5 | .455 | 69 | 6.3 | 10 | 1 | .100 | 84.7 | .615 |
| Tim Hudson | Det | sp | 30 | 30 | 3 | .100 | 0 | 13 | .433 | 131 | 4.4 | 13 | 5 | .385 | 99.4 | .619 |
| Jason Isringhausen | Bos | cl | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 9 | .360 | 19.2 | .588 |
| Edwin Jackson | Min | mr | 22 | 3 | 0 | .000 | 0 | 1 | .333 | 19 | 6.3 | 10 | 2 | .200 | 55.7 | .548 |
| Zach Jackson* | Tex | sp | 23 | 8 | 0 | .000 | 0 | 2 | .250 | 32 | 4.0 | 12 | 7 | .583 | 67.8 | .583 |
| Chuck James* | Bos | sp | 24 | 21 | 0 | .000 | 0 | 13 | .619 | 108 | 5.1 | 12 | 3 | .250 | 92.0 | .595 |
| Bobby Jenks | KCR | cl | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 0 | .000 | 22.1 | .643 |
| Tyler Johnson* | Sea | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 37 | 13 | .351 | 24.7 | .532 |
| Todd Jones | Mtl | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 15.8 | .684 |
| Scott Kazmir* | Bos | sp | 22 | 27 | 1 | .037 | 0 | 16 | .593 | 146 | 5.4 | 12 | 2 | .167 | 101.4 | .624 |
| Randy Keisler* | Mtl | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 | 17.4 | .612 |
| Joe Kennedy* | Min | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 | 23.5 | .642 |
| Logan Kensing | Was | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 31 | 14 | .452 | 31.0 | .574 |
| Bobby Keppel | Bal | sp | 24 | 14 | 1 | .071 | 0 | 5 | .357 | 74 | 5.3 | 18 | 5 | .278 | 85.6 | .637 |
| Byung-Hyun Kim | Bos | sp | 27 | 30 | 0 | .000 | 0 | 15 | .500 | 193 | 6.4 | 24 | 6 | .250 | 97.1 | .604 |
| Dan Kolb | ChW | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 0 | .000 | 27.9 | .629 |
| Hong-Chih Kuo* | Bos | mr | 24 | 5 | 0 | .000 | 0 | 1 | .200 | 23 | 4.6 | 14 | 4 | .286 | 40.3 | .585 |
| John Lackey | Bal | sp | 27 | 38 | 1 | .026 | 1 | 23 | .605 | 167 | 4.4 | 32 | 14 | .438 | 109.0 | .635 |
| Brandon League | Min | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 | 35.6 | .678 |
| Brad Lidge | ChW | cl | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 4 | .308 | 21.8 | .589 |
| Francisco Liriano* | Min | sp | 22 | 23 | 3 | .130 | 3 | 12 | .522 | 123 | 5.3 | 11 | 4 | .364 | 102.3 | .657 |
| Esteban Loaiza | LAA | sp | 34 | 26 | 1 | .038 | 1 | 10 | .385 | 113 | 4.3 | 12 | 3 | .250 | 93.4 | .646 |
| Kameron Loe | NYY | sp | 24 | 4 | 0 | .000 | 0 | 1 | .250 | 12 | 3.0 | 5 | 2 | .400 | 66.8 | .622 |
| Boone Logan* | ChW | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 4 | .444 | 31.1 | .600 |
| Javier Lopez* | Tex | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 15.0 | .633 |
| Rodrigo Lopez | NYY | sp | 30 | 30 | 3 | .100 | 1 | 16 | .533 | 150 | 5.0 | 28 | 11 | .393 | 96.6 | .628 |
| Mark Lowe | Bos | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 33.3 | .614 |
| Ruddy Lugo | Was | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 36 | 10 | .278 | 22.7 | .599 |
| Ryan Madson | NYY | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 9 | .429 | 33.2 | .612 |
| Carlos Marmol | Bal | sp | 23 | 14 | 0 | .000 | 0 | 3 | .214 | 90 | 6.4 | 11 | 2 | .182 | 99.0 | .537 |
| Mike Maroth* | Tor | sp | 28 | 20 | 0 | .000 | 0 | 10 | .500 | 116 | 5.8 | 10 | 4 | .400 | 83.6 | .641 |
| Damaso Marte* | Was | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 37 | 5 | .135 | 17.9 | .587 |
| Carlos Martinez | Mtl | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 | 24.5 | .611 |
| Tom Mastny | Tex | cl | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 15.0 | .600 |
| Juan Mateo | KCR | sp | 23 | 4 | 0 | .000 | 0 | 1 | .250 | 15 | 3.8 | 3 | 0 | .000 | 96.0 | .573 |
| Dustin McGowan | Cle | mr | 24 | 7 | 0 | .000 | 0 | 1 | .143 | 30 | 4.3 | 17 | 5 | .294 | 54.4 | .556 |
| Marty McLeary | NYY | mr | 31 | 1 | 0 | .000 | 0 | 1 | 1.000 | 8 | 8.0 | 1 | 0 | .000 | 83.0 | .590 |
| Brian Meadows | Bal | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 27.0 | .655 |
| Gil Meche |   | sp | 27 | 32 | 1 | .031 | 0 | 13 | .406 | 181 | 5.7 | 24 | 8 | .333 | 90.3 | .597 |
| Brandon Medders | Mtl | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 8 | .381 | 28.5 | .596 |
| Jose Mesa | Bal | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 34 | 12 | .353 | 27.6 | .600 |
| Dan Miceli | Tor | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 22.5 | .589 |
| Trever Miller* | Det | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 3 | .158 | 21.7 | .636 |
| Eric Milton* | Cle | sp | 30 | 30 | 1 | .033 | 0 | 12 | .400 | 148 | 4.9 | 20 | 7 | .350 | 91.1 | .641 |
| Zach Miner | Det | sp | 24 | 13 | 1 | .077 | 0 | 6 | .462 | 61 | 4.7 | 6 | 1 | .167 | 93.1 | .627 |
| Brian Moehler | Sea | sp | 34 | 6 | 0 | .000 | 0 | 3 | .500 | 22 | 3.7 | 4 | 3 | .750 | 92.3 | .632 |
| Matt Morris | Mtl | sp | 31 | 18 | 1 | .056 | 0 | 9 | .500 | 80 | 4.4 | 9 | 5 | .556 | 96.3 | .626 |
| Jamie Moyer* | Tor | sp | 43 | 33 | 3 | .091 | 0 | 13 | .394 | 211 | 6.4 | 28 | 11 | .393 | 90.6 | .644 |
| Edward Mujica | Cle | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 22.3 | .767 |
| Mark Mulder* | Was | sp | 28 | 2 | 0 | .000 | 0 | 0 | .000 | 9 | 4.5 | 1 | 1 | 1.000 | 71.5 | .545 |
| Scott Munter | NYY | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 | 23.3 | .582 |
| Brett Myers | Oak | sp | 25 | 30 | 3 | .100 | 1 | 18 | .600 | 146 | 4.9 | 26 | 7 | .269 | 106.8 | .618 |
| Chris Narveson* | Min | mr | 24 | 5 | 0 | .000 | 0 | 1 | .200 | 31 | 6.2 | 2 | 2 | 1.000 | 92.0 | .563 |
| Joe Nathan | Was | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 21.2 | .679 |
| Joe Nelson | ChW | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 | 21.1 | .616 |
| Fernando Nieve | Bos | mr | 23 | 19 | 1 | .053 | 0 | 10 | .526 | 89 | 4.7 | 10 | 4 | .400 | 77.2 | .591 |
| Roberto Novoa | Sea | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 7 | .250 | 23.6 | .613 |
| Mike O'Connor* | KCR | sp | 25 | 16 | 0 | .000 | 0 | 3 | .188 | 85 | 5.3 | 18 | 8 | .444 | 78.3 | .595 |
| Ryan O'Malley* | Was | sp | 26 | 7 | 0 | .000 | 0 | 2 | .286 | 24 | 3.4 | 10 | 4 | .400 | 89.1 | .521 |
| Darren Oliver* |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 9 | .409 | 27.2 | .628 |
| Ramon Ortiz | NYY | sp | 33 | 29 | 0 | .000 | 0 | 9 | .310 | 136 | 4.7 | 29 | 7 | .241 | 88.5 | .640 |
| Russ Ortiz | Tor | mr | 32 | 12 | 0 | .000 | 0 | 2 | .167 | 60 | 5.0 | 13 | 6 | .462 | 81.3 | .585 |
| Vicente Padilla | KCR | sp | 28 | 31 | 2 | .065 | 2 | 18 | .581 | 145 | 4.7 | 22 | 6 | .273 | 90.9 | .640 |
| Jonathan Papelbon | Min | cl | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 17.2 | .680 |
| Chan Ho Park | ChW | sp | 33 | 22 | 5 | .227 | 1 | 14 | .636 | 116 | 5.3 | 17 | 6 | .353 | 103.3 | .630 |
| Jake Peavy | ChW | sp | 25 | 31 | 4 | .129 | 2 | 16 | .516 | 145 | 4.7 | 25 | 9 | .360 | 108.1 | .634 |
| Tony Pena | Oak | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 3 | .429 | 20.0 | .631 |
| Joel Peralta | Tex | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 6 | .222 | 20.4 | .628 |
| Odalis Perez* | Min | sp | 29 | 30 | 2 | .067 | 0 | 13 | .433 | 151 | 5.0 | 24 | 4 | .167 | 84.0 | .660 |
| Oliver Perez* | LAA | sp | 24 | 15 | 0 | .000 | 0 | 6 | .400 | 76 | 5.1 | 13 | 2 | .154 | 98.2 | .558 |
| Joel Pineiro | Sea | sp | 27 | 11 | 0 | .000 | 0 | 4 | .364 | 60 | 5.5 | 18 | 12 | .667 | 46.0 | .616 |
| Mark Prior | KCR | sp | 25 | 2 | 0 | .000 | 0 | 1 | .500 | 6 | 3.0 | 2 | 1 | .500 | 87.5 | .537 |
| Scott Proctor | NYY | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 8 | .500 | 21.9 | .641 |
| Brad Radke | Was | sp | 33 | 13 | 1 | .077 | 0 | 6 | .462 | 72 | 5.5 | 14 | 4 | .286 | 81.1 | .657 |
| Horacio Ramirez* | Tex | sp | 26 | 23 | 1 | .043 | 0 | 11 | .478 | 138 | 6.0 | 23 | 8 | .348 | 99.3 | .609 |
| Chris Ray | Cle | cl | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 16.4 | .591 |
| Mark Redman* | Mtl | sp | 32 | 31 | 1 | .032 | 0 | 13 | .419 | 118 | 3.8 | 18 | 10 | .556 | 90.4 | .621 |
| Chris Resop | Cle | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 3 | .136 | 23.0 | .584 |
| Anthony Reyes | KCR | sp | 24 | 12 | 0 | .000 | 0 | 4 | .333 | 66 | 5.5 | 9 | 4 | .444 | 73.5 | .601 |
| David Riske | ChW | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 7 | 1.000 | 20.9 | .576 |
| Mariano Rivera | Tor | cl | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 1 | .083 | 21.5 | .696 |
| Francisco Rodriguez | Tor | cl | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 6 | .429 | 26.3 | .643 |
| Kenny Rogers* | LAA | sp | 41 | 34 | 3 | .088 | 0 | 26 | .765 | 147 | 4.3 | 21 | 4 | .190 | 99.7 | .633 |
| Glendon Rusch* | LAA | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 5 | .556 | 31.0 | .623 |
| B.J. Ryan* | Was | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 0 | .000 | 22.3 | .629 |
| Kirk Saarloos | Bal | mr | 27 | 19 | 2 | .105 | 0 | 7 | .368 | 92 | 4.8 | 20 | 5 | .250 | 73.5 | .607 |
| C.C. Sabathia* |   | sp | 25 | 32 | 3 | .094 | 1 | 18 | .563 | 166 | 5.2 | 27 | 6 | .222 | 103.4 | .668 |
| Juan Salas | Oak | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 12.3 | .703 |
| Chris Sampson | NYY | mr | 28 | 3 | 0 | .000 | 0 | 3 | 1.000 | 13 | 4.3 | 3 | 0 | .000 | 82.7 | .690 |
| Anibal Sanchez | Was | sp | 22 | 21 | 1 | .048 | 0 | 12 | .571 | 111 | 5.3 | 23 | 6 | .261 | 100.5 | .574 |
| Duaner Sanchez | Mtl | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 13 | .619 | 31.8 | .586 |
| Johan Santana* | Sea | sp | 27 | 33 | 6 | .182 | 0 | 23 | .697 | 143 | 4.3 | 20 | 10 | .500 | 114.3 | .666 |
| Scott Sauerbeck* | ChW | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 1 | .077 | 23.6 | .567 |
| Joe Saunders* | Cle | sp | 25 | 17 | 2 | .118 | 0 | 10 | .588 | 80 | 4.7 | 16 | 2 | .125 | 101.5 | .612 |
| Scott Schoeneweis* | Tex | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 1 | .056 | 18.9 | .616 |
| Chris Schroder | Tex | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 34.3 | .505 |
| Rudy Seanez | Det | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 | 29.7 | .603 |
| Bobby Seay* | LAA | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 18.0 | .500 |
| Ben Sheets | Oak | sp | 27 | 22 | 7 | .318 | 1 | 14 | .636 | 96 | 4.4 | 5 | 4 | .800 | 111.3 | .692 |
| George Sherrill* | KCR | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 31 | 9 | .290 | 16.0 | .594 |
| Matt Smith* | Cle | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 17.5 | .619 |
| Kyle Snyder | Tex | sp | 28 | 10 | 0 | .000 | 0 | 4 | .400 | 37 | 3.7 | 24 | 9 | .375 | 44.1 | .651 |
| Rafael Soriano | Min | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 | 27.0 | .631 |
| Jeremy Sowers* | Det | sp | 23 | 17 | 3 | .176 | 0 | 7 | .412 | 60 | 3.5 | 6 | 3 | .500 | 91.4 | .642 |
| Brian Stokes | Oak | sp | 26 | 12 | 0 | .000 | 0 | 2 | .167 | 37 | 3.1 | 15 | 7 | .467 | 91.0 | .606 |
| Huston Street | NYY | cl | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 17.4 | .672 |
| Jeff Suppan | Was | sp | 31 | 33 | 0 | .000 | 0 | 15 | .455 | 153 | 4.6 | 25 | 8 | .320 | 93.5 | .614 |
| Taylor Tankersley* | Det | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 6 | .600 | 28.6 | .587 |
| Jack Taschner* | NYY | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 4.0 | .750 |
| Ty Taubenheim | ChW | sp | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 28.9 | .580 |
| Mike Timlin | Was | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 2 | .167 | 16.0 | .659 |
| Brett Tomko | NYY | mr | 33 | 23 | 1 | .043 | 0 | 9 | .391 | 99 | 4.3 | 15 | 4 | .267 | 101.1 | .651 |
| Salomon Torres | LAA | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 6 | .316 | 22.7 | .628 |
| Josh Towers | Tex | sp | 29 | 12 | 0 | .000 | 0 | 3 | .250 | 42 | 3.5 | 12 | 4 | .333 | 75.7 | .657 |
| Steve Trachsel | LAA | sp | 35 | 25 | 0 | .000 | 0 | 10 | .400 | 105 | 4.2 | 17 | 5 | .294 | 97.6 | .586 |
| Jose Veras | Oak | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 | 24.9 | .595 |
| Justin Verlander | Cle | sp | 23 | 32 | 4 | .125 | 2 | 20 | .625 | 110 | 3.4 | 23 | 10 | .435 | 101.4 | .627 |
| Ron Villone* | LAA | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 5 | .227 | 22.9 | .608 |
| Luis Vizcaino | Bos | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 6 | .240 | 20.0 | .632 |
| Ryan Vogelsong | Was | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 3 | .300 | 38.6 | .576 |
| Edinson Volquez | Mtl | sp | 22 | 11 | 0 | .000 | 0 | 4 | .364 | 64 | 5.8 | 11 | 3 | .273 | 90.4 | .607 |
| Billy Wagner* | Bos | cl | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 4 | .222 | 21.6 | .632 |
| Ryan Wagner | Oak | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 4 | .500 | 18.0 | .630 |
| Tim Wakefield | Sea | sp | 39 | 27 | 7 | .259 | 0 | 15 | .556 | 129 | 4.8 | 16 | 3 | .188 | 108.8 | .618 |
| John Wasdin | Oak | sp | 33 | 8 | 0 | .000 | 0 | 4 | .500 | 24 | 3.0 | 7 | 3 | .429 | 88.9 | .603 |
| Jarrod Washburn* | Det | sp | 31 | 31 | 1 | .032 | 0 | 15 | .484 | 167 | 5.4 | 29 | 10 | .345 | 92.7 | .638 |
| David Weathers | Det | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 5 | .200 | 21.2 | .601 |
| Brandon Webb | Det | sp | 27 | 33 | 6 | .182 | 1 | 22 | .667 | 164 | 5.0 | 13 | 4 | .308 | 104.5 | .661 |
| David Wells* | Bal | sp | 43 | 17 | 3 | .176 | 0 | 5 | .294 | 87 | 5.1 | 7 | 3 | .429 | 93.3 | .687 |
| Kip Wells | Mtl | sp | 29 | 16 | 0 | .000 | 0 | 5 | .313 | 68 | 4.3 | 22 | 12 | .545 | 97.2 | .576 |
| Jake Westbrook | Tex | sp | 28 | 31 | 6 | .194 | 3 | 18 | .581 | 143 | 4.6 | 21 | 9 | .429 | 107.8 | .645 |
| Dave Williams* | Tor | sp | 27 | 24 | 0 | .000 | 0 | 2 | .083 | 113 | 4.7 | 30 | 9 | .300 | 59.5 | .633 |
| Jerome Williams | Mtl | mr | 24 | 12 | 0 | .000 | 0 | 1 | .083 | 50 | 4.2 | 18 | 11 | .611 | 83.5 | .523 |
| Dontrelle Willis* | Was | sp | 24 | 34 | 5 | .147 | 3 | 23 | .676 | 189 | 5.6 | 26 | 13 | .500 | 100.8 | .609 |
| C.J. Wilson* | Min | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 2 | .182 | 23.6 | .622 |
| Matt Wise | ChW | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 3 | .500 | 24.6 | .639 |
| Kerry Wood | Mtl | sp | 29 | 9 | 0 | .000 | 0 | 1 | .111 | 37 | 4.1 | 8 | 6 | .750 | 99.4 | .574 |
| Mike Wood | Mtl | mr | 26 | 31 | 3 | .097 | 1 | 11 | .355 | 139 | 4.5 | 27 | 12 | .444 | 90.8 | .640 |
| Jaret Wright | Det | sp | 30 | 29 | 1 | .034 | 0 | 17 | .586 | 134 | 4.6 | 37 | 18 | .486 | 91.7 | .601 |
| Tyler Yates | Tor | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 39 | 8 | .205 | 24.9 | .590 |
| Shane Youman* | Min | sp | 26 | 7 | 0 | .000 | 0 | 4 | .571 | 48 | 6.9 | 7 | 1 | .143 | 102.3 | .556 |
| Victor Zambrano | Det | sp | 30 | 3 | 0 | .000 | 0 | 1 | .333 | 7 | 2.3 | 3 | 2 | .667 | 76.0 | .513 |
| Barry Zito* | ChW | sp | 28 | 34 | 3 | .088 | 2 | 24 | .706 | 152 | 4.5 | 23 | 6 | .261 | 106.7 | .603 |
| Joel Zumaya | KCR | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 2 | .080 | 29.7 | .596 |
| Relief |
| Name | Team | P | Age | SVO | S | SV% | BS | BS% | HLD | IR | IRS | IR% | G | GR | GF | NP/G | STR% |
| Jeremy Accardo | ChW | mr | 24 | 5 | 2 | .400 | 2 | .400 | 10 | 33 | 15 | .455 | 43 | 43 | 14 | 22.0 | .637 |
| Jeremy Affeldt* | Bos | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 1 | 12 | 2 | .167 | 30 | 19 | 8 | 47.2 | .587 |
| Cha Seung Baek | NYY | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 103.2 | .635 |
| Danys Baez | Mtl | mr | 28 | 2 | 1 | .500 | 1 | .500 | 3 | 35 | 19 | .543 | 57 | 57 | 31 | 23.6 | .643 |
| Kevin Barry | Sea | mr | 27 | 4 | 2 | .500 | 0 | .000 | 1 | 7 | 5 | .714 | 8 | 8 | 3 | 14.8 | .534 |
| Miguel Batista | Sea | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 26 | 1 | 1 | 96.3 | .590 |
| Rick Bauer | Sea | mr | 29 | 3 | 2 | .667 | 1 | .333 | 7 | 44 | 19 | .432 | 56 | 56 | 29 | 22.7 | .617 |
| Jonah Bayliss | ChW | mr | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 1 | 1 | 0 | 18.0 | .500 |
| Josh Beckett | KCR | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 100.1 | .635 |
| Joe Beimel* | Det | mr | 29 | 5 | 1 | .200 | 3 | .600 | 6 | 23 | 4 | .174 | 32 | 32 | 17 | 18.2 | .656 |
| Armando Benitez | ChW | cl | 33 | 6 | 1 | .167 | 4 | .667 | 5 | 17 | 3 | .176 | 19 | 19 | 5 | 24.2 | .578 |
| Joaquin Benoit | Tor | mr | 28 | 7 | 2 | .286 | 2 | .286 | 1 | 72 | 23 | .319 | 62 | 62 | 8 | 34.8 | .627 |
| Kris Benson | ChW | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 97.2 | .638 |
| Jason Bergmann | KCR | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 3 | 2 | 12.7 | .579 |
| Adam Bernero | Oak | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 61.7 | .676 |
| Rafael Betancourt | Oak | mr | 31 | 32 | 28 | .875 | 4 | .125 | 0 | 23 | 6 | .261 | 52 | 52 | 46 | 16.9 | .709 |
| Jeremy Bonderman | Oak | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 109.0 | .645 |
| Joe Borowski | KCR | cl | 35 | 5 | 3 | .600 | 2 | .400 | 12 | 46 | 14 | .304 | 64 | 64 | 23 | 24.5 | .615 |
| Chad Bradford | Bos | mr | 31 | 13 | 6 | .462 | 6 | .462 | 8 | 44 | 11 | .250 | 58 | 58 | 18 | 21.2 | .673 |
| Bill Bray* | Bos | mr | 23 | 4 | 2 | .500 | 1 | .250 | 0 | 5 | 1 | .200 | 13 | 13 | 10 | 29.2 | .600 |
| Craig Breslow* | Bal | mr | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 4 | 3 | .750 | 6 | 6 | 0 | 19.7 | .492 |
| Chris Britton | Cle | mr | 23 | 2 | 1 | .500 | 1 | .500 | 2 | 31 | 12 | .387 | 28 | 28 | 5 | 27.0 | .624 |
| Doug Brocail | KCR | mr | 39 | 2 | 0 | .000 | 1 | .500 | 5 | 19 | 8 | .421 | 29 | 29 | 15 | 22.7 | .653 |
| Brian Bruney | Cle | mr | 24 | 1 | 1 | 1.000 | 0 | .000 | 5 | 17 | 2 | .118 | 17 | 17 | 4 | 26.6 | .558 |
| Taylor Buchholz | ChW | sp | 24 | 4 | 1 | .250 | 2 | .500 | 4 | 39 | 8 | .205 | 56 | 56 | 29 | 25.7 | .645 |
| Paul Byrd | Tor | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 3 | 1.000 | 35 | 3 | 2 | 78.5 | .655 |
| Daniel Cabrera | Cle | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 104.3 | .563 |
| Matt Cain | NYY | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 101.4 | .587 |
| Kiko Calero | Bal | mr | 31 | 7 | 2 | .286 | 4 | .571 | 19 | 49 | 9 | .184 | 76 | 76 | 20 | 23.2 | .602 |
| Shawn Camp | Oak | mr | 30 | 2 | 0 | .000 | 2 | 1.000 | 5 | 18 | 9 | .500 | 27 | 27 | 12 | 23.1 | .657 |
| Matt Capps | Sea | mr | 22 | 28 | 20 | .714 | 6 | .214 | 2 | 45 | 11 | .244 | 61 | 61 | 53 | 17.6 | .686 |
| Chris Capuano* | NYY | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 92.5 | .660 |
| Chris Carpenter | Tex | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 1 | 1 | 104.0 | .645 |
| Hector Carrasco | Min | mr | 36 | 3 | 2 | .667 | 1 | .333 | 13 | 41 | 10 | .244 | 58 | 51 | 19 | 35.7 | .642 |
| Fabio Castro* | Tor | mr | 21 | 2 | 1 | .500 | 1 | .500 | 0 | 3 | 0 | .000 | 5 | 5 | 5 | 20.8 | .587 |
| Gustavo Chacin* | Bal | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 95.7 | .628 |
| Shawn Chacon | Det | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 41 | 16 | .390 | 41 | 39 | 15 | 42.6 | .593 |
| Bruce Chen* | Cle | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 | 82.8 | .622 |
| Vinnie Chulk | Tex | mr | 27 | 2 | 1 | .500 | 1 | .500 | 5 | 47 | 22 | .468 | 46 | 46 | 12 | 26.4 | .611 |
| Brandon Claussen* | LAA | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 91.6 | .608 |
| Bartolo Colon | Sea | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 92.0 | .658 |
| Clay Condrey | Bos | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 0 | .000 | 5 | 5 | 1 | 24.8 | .710 |
| Tim Corcoran | Tex | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 98.1 | .580 |
| Francisco Cordero | Tex | cl | 31 | 42 | 37 | .881 | 5 | .119 | 3 | 46 | 8 | .174 | 74 | 74 | 61 | 18.5 | .626 |
| Lance Cormier | Oak | mr | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 5 | 1 | .200 | 18 | 7 | 6 | 68.0 | .606 |
| Manuel Corpas | Mtl | mr | 23 | 1 | 0 | .000 | 1 | 1.000 | 2 | 14 | 6 | .429 | 22 | 22 | 5 | 24.4 | .638 |
| Juan Cruz | Min | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 99.8 | .588 |
| Jason Davis | KCR | mr | 26 | 1 | 1 | 1.000 | 0 | .000 | 1 | 8 | 3 | .375 | 8 | 8 | 4 | 18.3 | .753 |
| Zach Day | Bal | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 3 | 2 | 48.0 | .579 |
| Manny Delcarmen | Cle | mr | 24 | 3 | 1 | .333 | 2 | .667 | 13 | 50 | 10 | .200 | 47 | 47 | 16 | 20.3 | .640 |
| Ryan Dempster | LAA | cl | 29 | 22 | 22 | 1.000 | 0 | .000 | 6 | 36 | 9 | .250 | 60 | 60 | 45 | 17.6 | .579 |
| Joey Devine | Bos | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 0 | 29.0 | .534 |
| Scott Downs* | LAA | mr | 30 | 2 | 2 | 1.000 | 0 | .000 | 7 | 19 | 3 | .158 | 26 | 23 | 10 | 34.2 | .602 |
| Brandon Duckworth | Cle | sp | 30 | 2 | 1 | .500 | 0 | .000 | 0 | 9 | 4 | .444 | 18 | 14 | 9 | 46.5 | .601 |
| Zach Duke* | Tor | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 93.0 | .609 |
| Adam Eaton | LAA | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 89.4 | .637 |
| Joey Eischen* | Mtl | mr | 36 | 0 | 0 | .000 | 0 | .000 | 2 | 24 | 13 | .542 | 18 | 18 | 3 | 26.8 | .506 |
| Kelvim Escobar | Min | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 103.4 | .644 |
| Shawn Estes* | Oak | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 85.4 | .597 |
| Seth Etherton | ChW | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 65.7 | .589 |
| Dana Eveland* | Cle | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 11 | 2 | 1 | 76.5 | .614 |
| Willie Eyre | NYY | mr | 27 | 2 | 1 | .500 | 1 | .500 | 1 | 41 | 15 | .366 | 45 | 45 | 18 | 30.6 | .627 |
| Kyle Farnsworth | Det | mr | 30 | 33 | 27 | .818 | 6 | .182 | 1 | 28 | 8 | .286 | 49 | 49 | 44 | 19.6 | .644 |
| Ryan Feierabend* | Det | sp | 20 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 99.8 | .604 |
| Pedro Feliciano* | NYY | mr | 29 | 5 | 1 | .200 | 4 | .800 | 6 | 34 | 13 | .382 | 48 | 48 | 17 | 20.7 | .615 |
| Ron Flores* | KCR | mr | 26 | 2 | 1 | .500 | 0 | .000 | 2 | 7 | 0 | .000 | 16 | 16 | 5 | 27.6 | .633 |
| Casey Fossum* | KCR | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 0 | 0 | 93.2 | .616 |
| Keith Foulke | Oak | mr | 33 | 8 | 4 | .500 | 4 | .500 | 9 | 44 | 15 | .341 | 45 | 45 | 23 | 16.6 | .690 |
| Jeff Francis* | Bos | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 0 | 0 | 104.1 | .614 |
| Ryan Franklin | Tex | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 40 | 16 | .400 | 52 | 52 | 7 | 24.9 | .606 |
| Brian Fuentes* | Bal | cl | 30 | 32 | 23 | .719 | 9 | .281 | 4 | 57 | 21 | .368 | 75 | 75 | 55 | 22.5 | .603 |
| Aaron Fultz* | Cle | mr | 32 | 3 | 2 | .667 | 0 | .000 | 7 | 28 | 5 | .179 | 44 | 40 | 16 | 22.6 | .636 |
| Kason Gabbard* | Tor | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 | 91.3 | .537 |
| Jon Garland | Mtl | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 95.9 | .662 |
| Matt Garza | Bal | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 7 | 1 | 0 | 84.6 | .611 |
| Geoff Geary | LAA | mr | 29 | 11 | 7 | .636 | 4 | .364 | 7 | 41 | 9 | .220 | 62 | 62 | 24 | 24.9 | .650 |
| Jimmy Gobble* | Cle | mr | 24 | 3 | 0 | .000 | 2 | .667 | 5 | 37 | 13 | .351 | 41 | 31 | 7 | 43.3 | .627 |
| Enrique Gonzalez | KCR | sp | 23 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 12 | 1 | 0 | 76.0 | .588 |
| Geremi Gonzalez | Oak | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 7 | 3 | .429 | 19 | 15 | 11 | 46.6 | .614 |
| Tom Gordon | Bal | cl | 38 | 11 | 9 | .818 | 2 | .182 | 7 | 51 | 16 | .314 | 64 | 64 | 29 | 23.7 | .633 |
| Tom Gorzelanny* | Sea | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 | 101.6 | .572 |
| John Grabow* | KCR | mr | 27 | 3 | 2 | .667 | 1 | .333 | 0 | 24 | 4 | .167 | 41 | 41 | 18 | 26.8 | .613 |
| Zack Greinke | Bos | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 3 | 3 | 1 | 20.7 | .629 |
| Eddie Guardado* | Mtl | cl | 35 | 2 | 0 | .000 | 1 | .500 | 4 | 23 | 12 | .522 | 43 | 43 | 18 | 21.6 | .638 |
| Charlie Haeger | Cle | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 14 | 8 | .571 | 13 | 9 | 2 | 70.1 | .528 |
| Jason Hammel | ChW | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 | 78.6 | .570 |
| Chris Hammond* | Tor | mr | 40 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 2 | 2 | 0 | 47.5 | .621 |
| Josh Hancock | NYY | mr | 28 | 3 | 1 | .333 | 2 | .667 | 2 | 25 | 8 | .320 | 37 | 37 | 18 | 27.9 | .632 |
| Aaron Harang | Was | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 100.3 | .630 |
| Travis Harper | LAA | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 2 | 15 | 10 | .667 | 18 | 18 | 6 | 31.4 | .604 |
| Chad Harville | Det | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 22 | 5 | .227 | 17 | 17 | 12 | 37.2 | .570 |
| LaTroy Hawkins | Cle | mr | 33 | 7 | 2 | .286 | 4 | .571 | 15 | 32 | 9 | .281 | 58 | 58 | 20 | 16.4 | .661 |
| Aaron Heilman | Oak | mr | 27 | 6 | 0 | .000 | 4 | .667 | 7 | 30 | 11 | .367 | 33 | 33 | 10 | 23.6 | .618 |
| Rick Helling | Bos | mr | 35 | 0 | 0 | .000 | 0 | .000 | 3 | 4 | 1 | .250 | 15 | 12 | 3 | 30.3 | .652 |
| Mark Hendrickson* | LAA | sp | 32 | 1 | 0 | .000 | 0 | .000 | 1 | 7 | 2 | .286 | 38 | 11 | 4 | 83.7 | .604 |
| Sean Henn* | Tex | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 1 | 1 | 60.0 | .600 |
| Clay Hensley | Bal | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 97.8 | .601 |
| Felix Hernandez | Min | sp | 20 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 104.8 | .637 |
| Livan Hernandez | Was | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 99.8 | .617 |
| Orlando Hernandez | Sea | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 102.4 | .605 |
| Roberto Hernandez | Tor | mr | 41 | 5 | 3 | .600 | 2 | .400 | 3 | 46 | 17 | .370 | 64 | 64 | 25 | 28.4 | .618 |
| Runelvys Hernandez | ChW | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 78.1 | .600 |
| Jason Hirsh | Tex | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 | 88.5 | .587 |
| J.P. Howell* | Bos | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 0 | 0 | 84.7 | .615 |
| Tim Hudson | Det | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 99.4 | .619 |
| Jason Isringhausen | Bos | cl | 33 | 6 | 4 | .667 | 2 | .333 | 12 | 40 | 7 | .175 | 53 | 53 | 18 | 19.2 | .588 |
| Edwin Jackson | Min | mr | 22 | 0 | 0 | .000 | 0 | .000 | 2 | 8 | 0 | .000 | 16 | 13 | 8 | 55.7 | .548 |
| Zach Jackson* | Tex | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 67.8 | .583 |
| Chuck James* | Bos | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 1 | 0 | 92.0 | .595 |
| Bobby Jenks | KCR | cl | 25 | 36 | 29 | .806 | 7 | .194 | 1 | 37 | 12 | .324 | 57 | 57 | 49 | 22.1 | .643 |
| Tyler Johnson* | Sea | mr | 25 | 8 | 7 | .875 | 1 | .125 | 8 | 39 | 13 | .333 | 46 | 46 | 17 | 24.7 | .532 |
| Todd Jones | Mtl | cl | 38 | 30 | 26 | .867 | 4 | .133 | 0 | 33 | 13 | .394 | 53 | 53 | 47 | 15.8 | .684 |
| Scott Kazmir* | Bos | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 101.4 | .624 |
| Randy Keisler* | Mtl | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 14 | 5 | .357 | 8 | 8 | 1 | 17.4 | .612 |
| Joe Kennedy* | Min | mr | 27 | 0 | 0 | .000 | 0 | .000 | 7 | 40 | 11 | .275 | 34 | 34 | 13 | 23.5 | .642 |
| Logan Kensing | Was | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 43 | 13 | .302 | 42 | 42 | 11 | 31.0 | .574 |
| Bobby Keppel | Bal | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 85.6 | .637 |
| Byung-Hyun Kim | Bos | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 97.1 | .604 |
| Dan Kolb | ChW | mr | 31 | 1 | 1 | 1.000 | 0 | .000 | 0 | 16 | 10 | .625 | 22 | 22 | 6 | 27.9 | .629 |
| Hong-Chih Kuo* | Bos | mr | 24 | 1 | 1 | 1.000 | 0 | .000 | 3 | 16 | 3 | .188 | 30 | 25 | 14 | 40.3 | .585 |
| John Lackey | Bal | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 38 | 0 | 0 | 109.0 | .635 |
| Brandon League | Min | mr | 23 | 8 | 8 | 1.000 | 0 | .000 | 2 | 17 | 4 | .235 | 30 | 30 | 19 | 35.6 | .678 |
| Brad Lidge | ChW | cl | 29 | 44 | 33 | .750 | 11 | .250 | 1 | 45 | 19 | .422 | 62 | 62 | 48 | 21.8 | .589 |
| Francisco Liriano* | Min | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 102.3 | .657 |
| Esteban Loaiza | LAA | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 93.4 | .646 |
| Kameron Loe | NYY | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 66.8 | .622 |
| Boone Logan* | ChW | mr | 21 | 1 | 0 | .000 | 1 | 1.000 | 0 | 10 | 8 | .800 | 9 | 9 | 1 | 31.1 | .600 |
| Javier Lopez* | Tex | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 2 | 2 | 2 | 15.0 | .633 |
| Rodrigo Lopez | NYY | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 96.6 | .628 |
| Mark Lowe | Bos | mr | 23 | 6 | 4 | .667 | 2 | .333 | 2 | 12 | 2 | .167 | 20 | 20 | 9 | 33.3 | .614 |
| Ruddy Lugo | Was | mr | 26 | 6 | 3 | .500 | 2 | .333 | 9 | 63 | 26 | .413 | 62 | 62 | 24 | 22.7 | .599 |
| Ryan Madson | NYY | mr | 25 | 2 | 2 | 1.000 | 0 | .000 | 3 | 34 | 10 | .294 | 33 | 33 | 8 | 33.2 | .612 |
| Carlos Marmol | Bal | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 15 | 1 | 1 | 99.0 | .537 |
| Mike Maroth* | Tor | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 1 | 1 | 83.6 | .641 |
| Damaso Marte* | Was | mr | 31 | 4 | 2 | .500 | 2 | .500 | 15 | 55 | 18 | .327 | 59 | 59 | 12 | 17.9 | .587 |
| Carlos Martinez | Mtl | mr | 24 | 2 | 0 | .000 | 2 | 1.000 | 1 | 20 | 9 | .450 | 22 | 22 | 12 | 24.5 | .611 |
| Tom Mastny | Tex | cl | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 1 | 1 | 1 | 15.0 | .600 |
| Juan Mateo | KCR | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 96.0 | .573 |
| Dustin McGowan | Cle | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 10 | 5 | .500 | 17 | 10 | 2 | 54.4 | .556 |
| Marty McLeary | NYY | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 83.0 | .590 |
| Brian Meadows | Bal | mr | 30 | 4 | 2 | .500 | 2 | .500 | 0 | 11 | 3 | .273 | 13 | 13 | 11 | 27.0 | .655 |
| Gil Meche |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 90.3 | .597 |
| Brandon Medders | Mtl | mr | 26 | 3 | 1 | .333 | 2 | .667 | 7 | 61 | 29 | .475 | 68 | 68 | 29 | 28.5 | .596 |
| Jose Mesa | Bal | mr | 40 | 6 | 3 | .500 | 3 | .500 | 2 | 67 | 26 | .388 | 64 | 64 | 24 | 27.6 | .600 |
| Dan Miceli | Tor | mr | 35 | 4 | 3 | .750 | 1 | .250 | 1 | 19 | 6 | .316 | 17 | 17 | 14 | 22.5 | .589 |
| Trever Miller* | Det | mr | 33 | 4 | 2 | .500 | 1 | .250 | 7 | 23 | 6 | .261 | 45 | 45 | 25 | 21.7 | .636 |
| Eric Milton* | Cle | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 91.1 | .641 |
| Zach Miner | Det | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 93.1 | .627 |
| Brian Moehler | Sea | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 92.3 | .632 |
| Matt Morris | Mtl | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 96.3 | .626 |
| Jamie Moyer* | Tor | sp | 43 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 90.6 | .644 |
| Edward Mujica | Cle | mr | 22 | 0 | 0 | .000 | 0 | .000 | 1 | 11 | 3 | .273 | 11 | 11 | 7 | 22.3 | .767 |
| Mark Mulder* | Was | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 71.5 | .545 |
| Scott Munter | NYY | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 8 | 4 | .500 | 12 | 12 | 5 | 23.3 | .582 |
| Brett Myers | Oak | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 106.8 | .618 |
| Chris Narveson* | Min | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 92.0 | .563 |
| Joe Nathan | Was | cl | 31 | 23 | 23 | 1.000 | 0 | .000 | 4 | 47 | 5 | .106 | 64 | 64 | 46 | 21.2 | .679 |
| Joe Nelson | ChW | mr | 31 | 3 | 3 | 1.000 | 0 | .000 | 7 | 24 | 4 | .167 | 27 | 27 | 11 | 21.1 | .616 |
| Fernando Nieve | Bos | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 26 | 7 | 3 | 77.2 | .591 |
| Roberto Novoa | Sea | mr | 26 | 4 | 0 | .000 | 2 | .500 | 8 | 53 | 18 | .340 | 65 | 65 | 21 | 23.6 | .613 |
| Mike O'Connor* | KCR | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 78.3 | .595 |
| Ryan O'Malley* | Was | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 | 89.1 | .521 |
| Darren Oliver* |   | mr | 35 | 1 | 0 | .000 | 1 | 1.000 | 9 | 42 | 17 | .405 | 50 | 50 | 20 | 27.2 | .628 |
| Ramon Ortiz | NYY | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 88.5 | .640 |
| Russ Ortiz | Tor | mr | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 81.3 | .585 |
| Vicente Padilla | KCR | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 90.9 | .640 |
| Jonathan Papelbon | Min | cl | 25 | 48 | 41 | .854 | 7 | .146 | 1 | 34 | 11 | .324 | 63 | 63 | 60 | 17.2 | .680 |
| Chan Ho Park | ChW | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 0 | 0 | 103.3 | .630 |
| Jake Peavy | ChW | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 108.1 | .634 |
| Tony Pena | Oak | mr | 24 | 1 | 1 | 1.000 | 0 | .000 | 5 | 21 | 8 | .381 | 27 | 27 | 8 | 20.0 | .631 |
| Joel Peralta | Tex | mr | 30 | 3 | 1 | .333 | 2 | .667 | 13 | 51 | 17 | .333 | 71 | 71 | 24 | 20.4 | .628 |
| Odalis Perez* | Min | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 84.0 | .660 |
| Oliver Perez* | LAA | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 | 98.2 | .558 |
| Joel Pineiro | Sea | sp | 27 | 1 | 1 | 1.000 | 0 | .000 | 0 | 20 | 9 | .450 | 38 | 27 | 18 | 46.0 | .616 |
| Mark Prior | KCR | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 87.5 | .537 |
| Scott Proctor | NYY | mr | 29 | 8 | 4 | .500 | 4 | .500 | 11 | 53 | 8 | .151 | 65 | 65 | 35 | 21.9 | .641 |
| Brad Radke | Was | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 81.1 | .657 |
| Horacio Ramirez* | Tex | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 99.3 | .609 |
| Chris Ray | Cle | cl | 24 | 32 | 29 | .906 | 3 | .094 | 1 | 30 | 11 | .367 | 49 | 49 | 46 | 16.4 | .591 |
| Mark Redman* | Mtl | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 90.4 | .621 |
| Chris Resop | Cle | mr | 23 | 3 | 1 | .333 | 2 | .667 | 1 | 29 | 16 | .552 | 37 | 37 | 11 | 23.0 | .584 |
| Anthony Reyes | KCR | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 73.5 | .601 |
| David Riske | ChW | mr | 29 | 0 | 0 | .000 | 0 | .000 | 2 | 9 | 4 | .444 | 17 | 17 | 10 | 20.9 | .576 |
| Mariano Rivera | Tor | cl | 36 | 14 | 7 | .500 | 7 | .500 | 6 | 47 | 16 | .340 | 68 | 68 | 40 | 21.5 | .696 |
| Francisco Rodriguez | Tor | cl | 24 | 10 | 9 | .900 | 1 | .100 | 7 | 27 | 5 | .185 | 67 | 67 | 41 | 26.3 | .643 |
| Kenny Rogers* | LAA | sp | 41 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 99.7 | .633 |
| Glendon Rusch* | LAA | mr | 31 | 3 | 1 | .333 | 1 | .333 | 2 | 16 | 7 | .438 | 21 | 21 | 7 | 31.0 | .623 |
| B.J. Ryan* | Was | cl | 30 | 26 | 24 | .923 | 1 | .038 | 6 | 36 | 5 | .139 | 57 | 57 | 40 | 22.3 | .629 |
| Kirk Saarloos | Bal | mr | 27 | 1 | 0 | .000 | 0 | .000 | 1 | 11 | 0 | .000 | 29 | 10 | 7 | 73.5 | .607 |
| C.C. Sabathia* |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 103.4 | .668 |
| Juan Salas | Oak | mr | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 3 | 3 | 0 | 12.3 | .703 |
| Chris Sampson | NYY | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 82.7 | .690 |
| Anibal Sanchez | Was | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 | 100.5 | .574 |
| Duaner Sanchez | Mtl | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 27 | 14 | .519 | 35 | 35 | 8 | 31.8 | .586 |
| Johan Santana* | Sea | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 114.3 | .666 |
| Scott Sauerbeck* | ChW | mr | 34 | 2 | 0 | .000 | 2 | 1.000 | 4 | 14 | 6 | .429 | 14 | 14 | 2 | 23.6 | .567 |
| Joe Saunders* | Cle | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 101.5 | .612 |
| Scott Schoeneweis* | Tex | mr | 32 | 7 | 5 | .714 | 2 | .286 | 8 | 40 | 10 | .250 | 60 | 60 | 22 | 18.9 | .616 |
| Chris Schroder | Tex | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 3 | 3 | 2 | 34.3 | .505 |
| Rudy Seanez | Det | mr | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 9 | 3 | .333 | 14 | 14 | 8 | 29.7 | .603 |
| Bobby Seay* | LAA | mr | 28 | 1 | 1 | 1.000 | 0 | .000 | 1 | 0 | 0 | .000 | 3 | 3 | 2 | 18.0 | .500 |
| Ben Sheets | Oak | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 0 | 0 | 111.3 | .692 |
| George Sherrill* | KCR | mr | 29 | 3 | 1 | .333 | 2 | .667 | 20 | 46 | 13 | .283 | 62 | 62 | 13 | 16.0 | .594 |
| Matt Smith* | Cle | mr | 27 | 0 | 0 | .000 | 0 | .000 | 4 | 12 | 3 | .250 | 20 | 20 | 9 | 17.5 | .619 |
| Kyle Snyder | Tex | sp | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 22 | 10 | .455 | 37 | 27 | 14 | 44.1 | .651 |
| Rafael Soriano | Min | mr | 26 | 11 | 7 | .636 | 4 | .364 | 7 | 34 | 12 | .353 | 47 | 47 | 21 | 27.0 | .631 |
| Jeremy Sowers* | Det | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 91.4 | .642 |
| Brian Stokes | Oak | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 91.0 | .606 |
| Huston Street | NYY | cl | 22 | 31 | 29 | .935 | 2 | .065 | 2 | 30 | 12 | .400 | 56 | 56 | 50 | 17.4 | .672 |
| Jeff Suppan | Was | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 93.5 | .614 |
| Taylor Tankersley* | Det | mr | 23 | 3 | 3 | 1.000 | 0 | .000 | 1 | 34 | 15 | .441 | 28 | 28 | 9 | 28.6 | .587 |
| Jack Taschner* | NYY | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 1 | 1 | 1 | 4.0 | .750 |
| Ty Taubenheim | ChW | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 21 | 9 | .429 | 19 | 19 | 6 | 28.9 | .580 |
| Mike Timlin | Was | mr | 40 | 2 | 0 | .000 | 1 | .500 | 0 | 18 | 10 | .556 | 25 | 25 | 9 | 16.0 | .659 |
| Brett Tomko | NYY | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 101.1 | .651 |
| Salomon Torres | LAA | mr | 34 | 14 | 11 | .786 | 2 | .143 | 14 | 38 | 12 | .316 | 65 | 65 | 35 | 22.7 | .628 |
| Josh Towers | Tex | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 75.7 | .657 |
| Steve Trachsel | LAA | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 97.6 | .586 |
| Jose Veras | Oak | mr | 25 | 0 | 0 | .000 | 0 | .000 | 2 | 6 | 2 | .333 | 14 | 14 | 7 | 24.9 | .595 |
| Justin Verlander | Cle | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 101.4 | .627 |
| Ron Villone* | LAA | mr | 36 | 15 | 9 | .600 | 5 | .333 | 18 | 33 | 11 | .333 | 60 | 60 | 25 | 22.9 | .608 |
| Luis Vizcaino | Bos | mr | 31 | 11 | 7 | .636 | 4 | .364 | 14 | 44 | 13 | .295 | 60 | 60 | 24 | 20.0 | .632 |
| Ryan Vogelsong | Was | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 15 | 5 | .333 | 20 | 20 | 10 | 38.6 | .576 |
| Edinson Volquez | Mtl | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 0 | 0 | 90.4 | .607 |
| Billy Wagner* | Bos | cl | 34 | 33 | 27 | .818 | 6 | .182 | 7 | 47 | 16 | .340 | 66 | 66 | 44 | 21.6 | .632 |
| Ryan Wagner | Oak | mr | 23 | 1 | 0 | .000 | 0 | .000 | 1 | 11 | 2 | .182 | 15 | 15 | 9 | 18.0 | .630 |
| Tim Wakefield | Sea | sp | 39 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 108.8 | .618 |
| John Wasdin | Oak | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 88.9 | .603 |
| Jarrod Washburn* | Det | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 92.7 | .638 |
| David Weathers | Det | mr | 36 | 8 | 1 | .125 | 3 | .375 | 12 | 33 | 11 | .333 | 50 | 50 | 17 | 21.2 | .601 |
| Brandon Webb | Det | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 104.5 | .661 |
| David Wells* | Bal | sp | 43 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 93.3 | .687 |
| Kip Wells | Mtl | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 97.2 | .576 |
| Jake Westbrook | Tex | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 107.8 | .645 |
| Dave Williams* | Tor | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 | 59.5 | .633 |
| Jerome Williams | Mtl | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 83.5 | .523 |
| Dontrelle Willis* | Was | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 100.8 | .609 |
| C.J. Wilson* | Min | mr | 25 | 2 | 0 | .000 | 2 | 1.000 | 5 | 17 | 3 | .176 | 22 | 22 | 11 | 23.6 | .622 |
| Matt Wise | ChW | mr | 30 | 2 | 1 | .500 | 1 | .500 | 4 | 28 | 10 | .357 | 31 | 31 | 16 | 24.6 | .639 |
| Kerry Wood | Mtl | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 99.4 | .574 |
| Mike Wood | Mtl | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 90.8 | .640 |
| Jaret Wright | Det | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 91.7 | .601 |
| Tyler Yates | Tor | mr | 28 | 8 | 5 | .625 | 1 | .125 | 7 | 43 | 18 | .419 | 63 | 63 | 18 | 24.9 | .590 |
| Shane Youman* | Min | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 | 102.3 | .556 |
| Victor Zambrano | Det | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 76.0 | .513 |
| Barry Zito* | ChW | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 106.7 | .603 |
| Joel Zumaya | KCR | mr | 21 | 11 | 7 | .636 | 4 | .364 | 11 | 57 | 18 | .316 | 66 | 66 | 20 | 29.7 | .596 |