League pitching register -- 2006 American League
Regular season -- as of 10/30/2006
| Primary |
| Name | Team | P | Age | ERA | W | L | S | G | GS | CG | SHO | INN | H | R | ER | BB | K | HR | GDP |
| Jeremy Accardo | ChW | mr | 23 | 5.40 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 8.1 | 11 | 9 | 5 | 3 | 4 | 3 | 0 |
| Jose Acevedo | ChW | mr | 27 | 4.55 | 0 | 2 | 0 | 14 | 0 | 0 | 0 | 31.2 | 34 | 22 | 16 | 7 | 14 | 10 | 1 |
| Jeremy Affeldt* | Bos | mr | 26 | 2.52 | 4 | 3 | 6 | 54 | 0 | 0 | 0 | 78.2 | 81 | 26 | 22 | 32 | 66 | 5 | 9 |
| Wilson Alvarez* | Det | mr | 35 | 6.75 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 4.0 | 6 | 3 | 3 | 2 | 4 | 0 | 0 |
| Brian Anderson* | KCR | sp | 33 | 7.27 | 0 | 2 | 0 | 3 | 2 | 0 | 0 | 8.2 | 14 | 7 | 7 | 2 | 9 | 3 | 0 |
| Matt Anderson | Min | mr | 28 | 10.50 | 0 | 0 | 0 | 9 | 0 | 0 | 0 | 12.0 | 19 | 14 | 14 | 13 | 6 | 3 | 0 |
| Greg Aquino | Bal | mr | 27 | 6.79 | 2 | 0 | 0 | 31 | 0 | 0 | 0 | 51.2 | 58 | 40 | 39 | 23 | 56 | 11 | 1 |
| Ezequiel Astacio | Min | sp | 25 | 5.92 | 7 | 13 | 0 | 28 | 28 | 2 | 0 | 168.2 | 198 | 118 | 111 | 36 | 132 | 44 | 9 |
| Luis Ayala | Was | mr | 27 | 3.74 | 1 | 4 | 2 | 51 | 0 | 0 | 0 | 55.1 | 63 | 25 | 23 | 12 | 38 | 5 | 8 |
| Manny Aybar | Bos | mr | 33 | 5.98 | 0 | 1 | 0 | 30 | 0 | 0 | 0 | 52.2 | 69 | 38 | 35 | 22 | 51 | 11 | 2 |
| Danys Baez | Sea | cl | 27 | 4.02 | 4 | 1 | 2 | 60 | 0 | 0 | 0 | 96.1 | 89 | 44 | 43 | 31 | 60 | 10 | 14 |
| James Baldwin | Oak | mr | 33 | 3.79 | 2 | 2 | 1 | 20 | 0 | 0 | 0 | 38.0 | 41 | 17 | 16 | 8 | 14 | 6 | 3 |
| Cliff Bartosh* | Bos | mr | 25 | 6.50 | 0 | 1 | 0 | 29 | 0 | 0 | 0 | 45.2 | 46 | 35 | 33 | 23 | 41 | 18 | 3 |
| Jonah Bayliss | Bos | mr | 24 | 2.21 | 1 | 3 | 2 | 14 | 0 | 0 | 0 | 20.1 | 10 | 5 | 5 | 11 | 14 | 2 | 1 |
| Josh Beckett | KCR | sp | 25 | 3.01 | 14 | 7 | 0 | 32 | 32 | 3 | 3 | 212.0 | 178 | 73 | 71 | 69 | 206 | 13 | 16 |
| Armando Benitez | ChW | cl | 32 | 1.73 | 2 | 0 | 1 | 18 | 0 | 0 | 0 | 26.0 | 16 | 9 | 5 | 8 | 15 | 3 | 3 |
| Joaquin Benoit | Tor | mr | 27 | 2.13 | 5 | 4 | 0 | 11 | 10 | 0 | 0 | 71.2 | 52 | 18 | 17 | 23 | 73 | 5 | 3 |
| Kris Benson | ChW | sp | 30 | 4.35 | 13 | 14 | 0 | 28 | 28 | 6 | 1 | 184.1 | 197 | 99 | 89 | 49 | 96 | 36 | 20 |
| Jason Bergmann | KCR | mr | 23 | 1.82 | 1 | 0 | 2 | 13 | 1 | 0 | 0 | 24.2 | 13 | 6 | 5 | 11 | 23 | 1 | 1 |
| Rafael Betancourt | Oak | mr | 30 | 2.41 | 6 | 3 | 33 | 57 | 0 | 0 | 0 | 74.2 | 60 | 22 | 20 | 19 | 76 | 1 | 4 |
| Jeremy Bonderman | Oak | sp | 22 | 4.38 | 10 | 14 | 0 | 32 | 32 | 3 | 0 | 189.0 | 200 | 108 | 92 | 68 | 137 | 26 | 22 |
| Joe Borowski | Mtl | mr | 34 | 4.50 | 3 | 5 | 5 | 43 | 0 | 0 | 0 | 48.0 | 55 | 28 | 24 | 7 | 24 | 7 | 2 |
| Ricky Bottalico | Bos | mr | 35 | 4.93 | 6 | 5 | 4 | 46 | 0 | 0 | 0 | 69.1 | 75 | 42 | 38 | 26 | 47 | 6 | 7 |
| Blaine Boyer | Det | mr | 23 | 4.36 | 1 | 0 | 0 | 21 | 0 | 0 | 0 | 33.0 | 24 | 16 | 16 | 14 | 30 | 3 | 3 |
| Chad Bradford | Oak | mr | 30 | 6.29 | 1 | 1 | 0 | 20 | 0 | 0 | 0 | 24.1 | 38 | 19 | 17 | 4 | 10 | 3 | 3 |
| Craig Breslow* | Bal | mr | 24 | 0.00 | 0 | 1 | 1 | 3 | 0 | 0 | 0 | 3.0 | 3 | 1 | 0 | 3 | 0 | 0 | 2 |
| Doug Brocail | Tor | mr | 38 | 4.08 | 10 | 2 | 0 | 62 | 0 | 0 | 0 | 110.1 | 115 | 58 | 50 | 55 | 95 | 6 | 8 |
| Jim Brower | Cle | mr | 32 | 5.47 | 0 | 2 | 0 | 33 | 0 | 0 | 0 | 51.0 | 67 | 31 | 31 | 25 | 33 | 7 | 8 |
| Kevin Brown | Mtl | sp | 40 | 9.00 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 5.0 | 5 | 5 | 5 | 2 | 5 | 2 | 0 |
| Brian Bruney | NYY | cl | 23 | 7.25 | 0 | 0 | 0 | 14 | 0 | 0 | 0 | 22.1 | 30 | 22 | 18 | 18 | 23 | 3 | 4 |
| Ryan Bukvich | Min | mr | 27 | 11.00 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 9.0 | 12 | 11 | 11 | 10 | 11 | 3 | 0 |
| Bryan Bullington | LAA | mr | 24 | 13.50 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 4.2 | 6 | 8 | 7 | 1 | 2 | 2 | 0 |
| Nate Bump | Det | mr | 28 | 5.59 | 0 | 1 | 0 | 6 | 0 | 0 | 0 | 9.2 | 18 | 6 | 6 | 6 | 7 | 1 | 2 |
| Paul Byrd | Tor | sp | 34 | 4.33 | 12 | 12 | 0 | 32 | 32 | 5 | 0 | 216.0 | 230 | 110 | 104 | 31 | 114 | 26 | 11 |
| Tim Byrdak* | Sea | mr | 31 | 4.44 | 1 | 1 | 0 | 19 | 0 | 0 | 0 | 24.1 | 20 | 13 | 12 | 18 | 32 | 1 | 4 |
| Daniel Cabrera | Cle | sp | 24 | 3.84 | 9 | 13 | 0 | 33 | 33 | 2 | 2 | 189.2 | 157 | 88 | 81 | 91 | 208 | 12 | 4 |
| Matt Cain | NYY | sp | 20 | 2.25 | 2 | 2 | 0 | 4 | 4 | 3 | 2 | 32.0 | 19 | 8 | 8 | 12 | 22 | 2 | 4 |
| Kiko Calero | Bal | mr | 30 | 2.65 | 5 | 3 | 0 | 46 | 0 | 0 | 0 | 71.1 | 64 | 23 | 21 | 23 | 75 | 8 | 3 |
| Shawn Camp | KCR | mr | 29 | 4.15 | 0 | 1 | 0 | 3 | 0 | 0 | 0 | 4.1 | 5 | 6 | 2 | 1 | 2 | 2 | 0 |
| Matt Capps | Sea | mr | 21 | 13.50 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.1 | 5 | 2 | 2 | 1 | 0 | 1 | 1 |
| Chris Capuano* | NYY | sp | 26 | 5.04 | 14 | 17 | 0 | 39 | 39 | 4 | 1 | 239.1 | 242 | 142 | 134 | 106 | 170 | 29 | 15 |
| Chris Carpenter | Tex | sp | 30 | 3.43 | 14 | 10 | 0 | 38 | 38 | 7 | 2 | 254.1 | 229 | 109 | 97 | 63 | 241 | 27 | 21 |
| Hector Carrasco | LAA | mr | 35 | 2.66 | 4 | 5 | 8 | 63 | 2 | 0 | 0 | 105.0 | 80 | 33 | 31 | 41 | 83 | 12 | 11 |
| Lance Carter | Mtl | mr | 30 | 2.73 | 1 | 0 | 0 | 32 | 0 | 0 | 0 | 69.1 | 68 | 23 | 21 | 20 | 31 | 7 | 5 |
| Marcos Carvajal | KCR | mr | 20 | 4.07 | 3 | 2 | 0 | 33 | 0 | 0 | 0 | 73.0 | 65 | 38 | 33 | 31 | 60 | 9 | 7 |
| Frank Castillo | KCR | sp | 36 | 3.18 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 5.2 | 6 | 2 | 2 | 4 | 6 | 1 | 1 |
| Gustavo Chacin* | Bal | sp | 24 | 4.13 | 12 | 8 | 0 | 34 | 34 | 3 | 0 | 196.0 | 217 | 110 | 90 | 62 | 138 | 21 | 20 |
| Shawn Chacon | Det | sp | 27 | 4.07 | 12 | 9 | 0 | 25 | 25 | 2 | 2 | 163.2 | 143 | 77 | 74 | 56 | 65 | 14 | 15 |
| Bruce Chen* | Cle | sp | 28 | 3.95 | 8 | 16 | 0 | 33 | 31 | 4 | 1 | 200.2 | 184 | 100 | 88 | 74 | 129 | 24 | 23 |
| Jason Christiansen* | Mtl | mr | 35 | 0.00 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 5.2 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
| Vinnie Chulk | Tex | mr | 26 | 3.57 | 0 | 0 | 2 | 31 | 0 | 0 | 0 | 45.1 | 47 | 23 | 18 | 20 | 25 | 5 | 6 |
| Brandon Claussen* | LAA | sp | 26 | 4.85 | 13 | 12 | 0 | 34 | 34 | 3 | 1 | 196.2 | 211 | 113 | 106 | 63 | 130 | 21 | 14 |
| Jesus Colome | Cle | mr | 27 | 3.86 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 9.1 | 17 | 7 | 4 | 3 | 7 | 0 | 1 |
| Bartolo Colon | Sea | sp | 32 | 4.23 | 13 | 11 | 0 | 34 | 34 | 3 | 1 | 223.1 | 234 | 115 | 105 | 57 | 159 | 27 | 28 |
| Brian Cooper | Tor | mr | 30 | 0.00 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 3.0 | 2 | 0 | 0 | 1 | 1 | 0 | 1 |
| Francisco Cordero | Tex | cl | 30 | 3.21 | 6 | 4 | 27 | 51 | 0 | 0 | 0 | 56.0 | 55 | 22 | 20 | 28 | 75 | 5 | 3 |
| Doug Creek* | Was | mr | 36 | 3.97 | 0 | 1 | 0 | 8 | 0 | 0 | 0 | 11.1 | 13 | 5 | 5 | 3 | 9 | 2 | 0 |
| Juan Cruz | Min | mr | 26 | 8.20 | 1 | 4 | 0 | 64 | 0 | 0 | 0 | 94.1 | 133 | 90 | 86 | 52 | 120 | 22 | 4 |
| Jason Davis | KCR | mr | 25 | 3.70 | 2 | 1 | 0 | 6 | 4 | 0 | 0 | 24.1 | 25 | 11 | 10 | 7 | 16 | 1 | 4 |
| Zach Day | Bal | mr | 27 | 6.89 | 0 | 1 | 0 | 9 | 2 | 0 | 0 | 15.2 | 17 | 17 | 12 | 15 | 8 | 2 | 2 |
| Valerio de los Santos* | KCR | mr | 32 | 6.75 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 1.1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| Mike DeJean | Tor | mr | 34 | 4.20 | 5 | 4 | 4 | 61 | 0 | 0 | 0 | 85.2 | 86 | 46 | 40 | 36 | 61 | 9 | 9 |
| Manny Delcarmen | Cle | mr | 23 | 6.00 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | 12.0 | 18 | 9 | 8 | 7 | 12 | 2 | 2 |
| Ryan Dempster | LAA | cl | 28 | 3.36 | 4 | 7 | 16 | 45 | 0 | 0 | 0 | 56.1 | 57 | 24 | 21 | 27 | 49 | 0 | 11 |
| Elmer Dessens | Sea | mr | 34 | 2.79 | 8 | 5 | 0 | 16 | 16 | 1 | 1 | 106.1 | 103 | 37 | 33 | 22 | 53 | 10 | 11 |
| Joey Devine | Bos | mr | 21 | 8.26 | 0 | 1 | 0 | 16 | 0 | 0 | 0 | 28.1 | 34 | 26 | 26 | 12 | 10 | 10 | 4 |
| R.A. Dickey | KCR | mr | 30 | 6.08 | 1 | 2 | 0 | 6 | 4 | 0 | 0 | 23.2 | 25 | 19 | 16 | 17 | 18 | 5 | 3 |
| Craig Dingman | Det | mr | 31 | 2.35 | 1 | 0 | 0 | 14 | 0 | 0 | 0 | 23.0 | 21 | 6 | 6 | 5 | 20 | 3 | 3 |
| Juan Dominguez | Min | mr | 25 | 4.79 | 4 | 9 | 0 | 17 | 17 | 3 | 0 | 107.0 | 126 | 65 | 57 | 34 | 61 | 15 | 7 |
| Octavio Dotel | Oak | cl | 31 | 3.33 | 3 | 2 | 1 | 19 | 0 | 0 | 0 | 27.0 | 20 | 12 | 10 | 18 | 22 | 3 | 0 |
| Scott Downs* | LAA | sp | 29 | 4.48 | 4 | 3 | 0 | 38 | 1 | 0 | 0 | 62.1 | 56 | 33 | 31 | 25 | 54 | 6 | 9 |
| Zach Duke* | Tor | sp | 22 | 2.90 | 9 | 4 | 0 | 19 | 18 | 4 | 0 | 118.0 | 100 | 40 | 38 | 32 | 99 | 5 | 13 |
| Adam Eaton | LAA | sp | 27 | 4.72 | 6 | 12 | 0 | 25 | 25 | 1 | 0 | 154.1 | 167 | 95 | 81 | 47 | 109 | 20 | 8 |
| Scott Erickson | KCR | mr | 37 | 3.38 | 1 | 0 | 0 | 2 | 2 | 0 | 0 | 10.2 | 8 | 5 | 4 | 3 | 1 | 1 | 1 |
| Kelvim Escobar | Min | mr | 29 | 3.78 | 6 | 6 | 0 | 35 | 0 | 0 | 0 | 81.0 | 63 | 41 | 34 | 30 | 80 | 8 | 6 |
| Mike Esposito | Bos | sp | 23 | 6.23 | 0 | 3 | 0 | 4 | 4 | 0 | 0 | 17.1 | 25 | 14 | 12 | 8 | 3 | 2 | 1 |
| Shawn Estes* | Tor | sp | 32 | 4.33 | 8 | 6 | 0 | 23 | 23 | 0 | 0 | 135.0 | 137 | 66 | 65 | 57 | 48 | 19 | 22 |
| Seth Etherton | ChW | sp | 28 | 3.42 | 3 | 4 | 0 | 7 | 7 | 2 | 0 | 47.1 | 33 | 24 | 18 | 22 | 23 | 6 | 4 |
| Dana Eveland* | Cle | mr | 21 | 4.35 | 0 | 2 | 1 | 25 | 0 | 0 | 0 | 39.1 | 45 | 22 | 19 | 20 | 29 | 1 | 7 |
| Scott Eyre* | Oak | mr | 33 | 3.24 | 4 | 4 | 1 | 67 | 0 | 0 | 0 | 77.2 | 59 | 39 | 28 | 27 | 68 | 9 | 5 |
| Kyle Farnsworth | Det | mr | 29 | 1.48 | 9 | 6 | 6 | 63 | 0 | 0 | 0 | 91.0 | 62 | 18 | 15 | 33 | 129 | 4 | 6 |
| Jeff Fassero* | Tex | mr | 42 | 4.66 | 2 | 2 | 0 | 46 | 0 | 0 | 0 | 75.1 | 81 | 40 | 39 | 27 | 49 | 7 | 7 |
| Ron Flores* | KCR | mr | 25 | 3.60 | 0 | 2 | 3 | 12 | 0 | 0 | 0 | 15.0 | 18 | 9 | 6 | 3 | 9 | 3 | 2 |
| Josh Fogg | Bal | sp | 28 | 5.24 | 3 | 6 | 0 | 24 | 13 | 1 | 0 | 92.2 | 108 | 60 | 54 | 24 | 42 | 16 | 11 |
| Keith Foulke | Oak | cl | 32 | 9.39 | 3 | 0 | 0 | 24 | 0 | 0 | 0 | 30.2 | 49 | 33 | 32 | 13 | 19 | 13 | 0 |
| Jeff Francis* | Bos | sp | 24 | 4.10 | 7 | 12 | 0 | 26 | 26 | 0 | 0 | 160.1 | 165 | 79 | 73 | 67 | 101 | 12 | 14 |
| Brian Fuentes* | Bal | cl | 29 | 1.09 | 3 | 1 | 15 | 48 | 0 | 0 | 0 | 66.1 | 29 | 10 | 8 | 20 | 78 | 1 | 4 |
| Jairo Garcia | Bos | mr | 22 | 17.18 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 3.2 | 8 | 7 | 7 | 5 | 1 | 0 | 0 |
| Jon Garland | Mtl | sp | 25 | 3.56 | 8 | 3 | 0 | 16 | 16 | 2 | 1 | 103.2 | 96 | 43 | 41 | 23 | 61 | 9 | 5 |
| Dave Gassner* | Sea | sp | 26 | 4.50 | 0 | 1 | 0 | 3 | 2 | 0 | 0 | 10.0 | 13 | 5 | 5 | 3 | 3 | 1 | 0 |
| Geoff Geary | LAA | mr | 28 | 3.78 | 2 | 2 | 1 | 39 | 0 | 0 | 0 | 85.2 | 97 | 43 | 36 | 37 | 51 | 7 | 8 |
| Matt Ginter | KCR | mr | 27 | 0.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0.1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| Gary Glover | KCR | sp | 28 | 4.58 | 4 | 7 | 0 | 18 | 12 | 0 | 0 | 72.2 | 91 | 39 | 37 | 19 | 76 | 9 | 4 |
| Jimmy Gobble* | Cle | mr | 23 | 7.98 | 4 | 14 | 0 | 34 | 24 | 0 | 0 | 117.1 | 152 | 115 | 104 | 76 | 90 | 14 | 10 |
| Jeremi Gonzalez | Oak | mr | 30 | 4.58 | 1 | 4 | 0 | 17 | 7 | 0 | 0 | 59.0 | 73 | 38 | 30 | 15 | 40 | 7 | 5 |
| Tom Gordon | Bal | mr | 37 | 2.20 | 11 | 2 | 2 | 76 | 0 | 0 | 0 | 114.1 | 73 | 34 | 28 | 32 | 101 | 10 | 3 |
| John Grabow* | KCR | mr | 26 | 3.10 | 6 | 3 | 5 | 50 | 0 | 0 | 0 | 72.2 | 69 | 25 | 25 | 25 | 62 | 6 | 8 |
| Danny Graves | KCR | cl | 31 | 33.75 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 1.1 | 5 | 5 | 5 | 3 | 0 | 1 | 0 |
| Zack Greinke | Bos | sp | 21 | 6.59 | 4 | 15 | 0 | 26 | 26 | 0 | 0 | 139.1 | 198 | 113 | 102 | 54 | 74 | 19 | 7 |
| Buddy Groom* | Sea | mr | 39 | 4.50 | 1 | 0 | 0 | 7 | 0 | 0 | 0 | 2.0 | 4 | 1 | 1 | 0 | 0 | 0 | 1 |
| Kevin Gryboski | Bal | mr | 31 | 3.00 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 12.0 | 13 | 5 | 4 | 7 | 4 | 0 | 3 |
| Eddie Guardado* |   | cl | 34 | 2.97 | 5 | 3 | 9 | 52 | 0 | 0 | 0 | 78.2 | 61 | 29 | 26 | 18 | 68 | 7 | 6 |
| John Halama* | KCR | mr | 33 | 5.04 | 1 | 0 | 1 | 20 | 2 | 0 | 0 | 50.0 | 59 | 31 | 28 | 13 | 25 | 2 | 6 |
| Brad Halsey* | Mtl | sp | 24 | 4.40 | 7 | 3 | 0 | 16 | 16 | 1 | 0 | 100.1 | 100 | 52 | 49 | 28 | 55 | 14 | 12 |
| Mike Hampton* | Det | sp | 32 | 4.77 | 6 | 5 | 0 | 12 | 12 | 1 | 0 | 71.2 | 75 | 40 | 38 | 33 | 26 | 6 | 13 |
| Craig Hansen | Bos | mr | 21 | 6.23 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 13.0 | 19 | 11 | 9 | 4 | 5 | 4 | 1 |
| Aaron Harang | Was | sp | 27 | 2.82 | 15 | 7 | 0 | 29 | 29 | 3 | 3 | 201.1 | 165 | 69 | 63 | 55 | 154 | 13 | 9 |
| Chad Harville | Sea | mr | 28 | 4.41 | 5 | 1 | 2 | 35 | 0 | 0 | 0 | 51.0 | 48 | 27 | 25 | 27 | 40 | 7 | 10 |
| Shigetoshi Hasegawa | LAA | mr | 36 | 3.17 | 3 | 1 | 1 | 58 | 0 | 0 | 0 | 125.0 | 122 | 47 | 44 | 37 | 62 | 8 | 6 |
| LaTroy Hawkins | Cle | mr | 32 | 5.59 | 4 | 5 | 18 | 59 | 0 | 0 | 0 | 66.0 | 93 | 47 | 41 | 17 | 48 | 6 | 10 |
| Aaron Heilman | Oak | mr | 26 | 3.12 | 7 | 4 | 0 | 54 | 11 | 1 | 1 | 156.0 | 125 | 59 | 54 | 48 | 148 | 16 | 16 |
| Mark Hendrickson* | LAA | sp | 31 | 5.86 | 5 | 9 | 0 | 20 | 20 | 0 | 0 | 113.2 | 151 | 79 | 74 | 37 | 59 | 17 | 10 |
| Clay Hensley | Bal | mr | 25 | 1.74 | 0 | 1 | 0 | 5 | 0 | 0 | 0 | 10.1 | 2 | 3 | 2 | 4 | 8 | 1 | 2 |
| Dustin Hermanson | Bal | cl | 32 | 3.25 | 3 | 7 | 15 | 57 | 0 | 0 | 0 | 74.2 | 63 | 29 | 27 | 24 | 51 | 9 | 5 |
| Felix Hernandez | Min | sp | 19 | 2.18 | 8 | 2 | 0 | 16 | 16 | 1 | 1 | 111.1 | 81 | 29 | 27 | 38 | 121 | 5 | 7 |
| Livan Hernandez | Was | sp | 30 | 5.34 | 11 | 16 | 0 | 33 | 33 | 2 | 0 | 194.0 | 261 | 127 | 115 | 63 | 121 | 22 | 17 |
| Orlando Hernandez | Tor | sp | 35 | 4.37 | 9 | 6 | 0 | 25 | 25 | 2 | 0 | 140.0 | 141 | 74 | 68 | 52 | 117 | 19 | 14 |
| Roberto Hernandez | Tex | mr | 40 | 3.06 | 9 | 6 | 4 | 42 | 0 | 0 | 0 | 64.2 | 59 | 27 | 22 | 23 | 53 | 4 | 5 |
| Runelvys Hernandez | ChW | sp | 27 | 6.81 | 4 | 16 | 0 | 29 | 29 | 0 | 0 | 148.0 | 166 | 123 | 112 | 78 | 89 | 22 | 11 |
| Trevor Hoffman | Det | cl | 37 | 1.65 | 2 | 4 | 41 | 54 | 0 | 0 | 0 | 71.0 | 55 | 13 | 13 | 14 | 77 | 3 | 4 |
| D.J. Houlton | KCR | sp | 25 | 10.53 | 0 | 7 | 0 | 18 | 10 | 0 | 0 | 47.0 | 78 | 60 | 55 | 28 | 29 | 13 | 3 |
| J.P. Howell* |   | sp | 22 | 4.16 | 3 | 4 | 0 | 12 | 12 | 0 | 0 | 67.0 | 62 | 31 | 31 | 38 | 59 | 9 | 8 |
| Luke Hudson | Was | sp | 28 | 0.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1.0 | 1 | 3 | 0 | 1 | 1 | 0 | 0 |
| Tim Hudson | Det | sp | 29 | 4.16 | 11 | 12 | 0 | 32 | 32 | 5 | 2 | 207.2 | 205 | 103 | 96 | 54 | 109 | 25 | 31 |
| Kazuhisa Ishii* | Oak | sp | 31 | 6.38 | 4 | 13 | 0 | 20 | 20 | 0 | 0 | 96.0 | 109 | 78 | 68 | 42 | 49 | 19 | 11 |
| Jason Isringhausen | Sea | cl | 32 | 3.30 | 3 | 8 | 33 | 60 | 0 | 0 | 0 | 73.2 | 54 | 28 | 27 | 19 | 60 | 6 | 11 |
| Edwin Jackson | Min | sp | 21 | 7.49 | 0 | 5 | 0 | 8 | 8 | 0 | 0 | 45.2 | 54 | 45 | 38 | 26 | 21 | 5 | 1 |
| Chuck James* | Bos | mr | 23 | 5.40 | 0 | 0 | 1 | 7 | 0 | 0 | 0 | 8.1 | 6 | 5 | 5 | 5 | 4 | 2 | 0 |
| Bobby Jenks | KCR | mr | 24 | 3.04 | 5 | 7 | 13 | 44 | 0 | 0 | 0 | 83.0 | 65 | 30 | 28 | 29 | 114 | 3 | 5 |
| Jason Johnson | Tex | sp | 31 | 4.18 | 14 | 5 | 0 | 24 | 24 | 4 | 1 | 161.2 | 178 | 79 | 75 | 42 | 73 | 19 | 25 |
| Tyler Johnson* | Sea | mr | 24 | 0.00 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 2.0 | 2 | 0 | 0 | 0 | 2 | 0 | 0 |
| Jorge Julio | Cle | mr | 26 | 5.08 | 3 | 1 | 1 | 35 | 0 | 0 | 0 | 39.0 | 50 | 23 | 22 | 12 | 44 | 6 | 2 |
| Scott Kazmir* | Bos | sp | 21 | 3.61 | 6 | 13 | 0 | 29 | 29 | 1 | 0 | 182.0 | 152 | 89 | 73 | 98 | 168 | 16 | 17 |
| Joe Kennedy* | Min | sp | 26 | 5.97 | 4 | 15 | 0 | 30 | 30 | 2 | 0 | 167.1 | 220 | 123 | 111 | 58 | 104 | 18 | 14 |
| Byung-Hyun Kim | LAA | sp | 26 | 5.49 | 0 | 2 | 0 | 4 | 3 | 1 | 0 | 19.2 | 19 | 12 | 12 | 9 | 13 | 1 | 1 |
| Steve Kline* | Cle | mr | 32 | 7.22 | 2 | 1 | 4 | 35 | 0 | 0 | 0 | 38.2 | 50 | 33 | 31 | 12 | 31 | 11 | 4 |
| Dae-Sung Koo* | Sea | mr | 35 | 3.28 | 0 | 1 | 2 | 15 | 0 | 0 | 0 | 24.2 | 22 | 11 | 9 | 7 | 22 | 2 | 1 |
| Mike Koplove | Tor | mr | 28 | 4.53 | 1 | 1 | 1 | 30 | 0 | 0 | 0 | 47.2 | 41 | 28 | 24 | 16 | 32 | 4 | 2 |
| Hong-Chih Kuo* | Bos | mr | 23 | 4.06 | 0 | 1 | 1 | 13 | 0 | 0 | 0 | 31.0 | 26 | 15 | 14 | 11 | 42 | 7 | 3 |
| John Lackey | Bal | sp | 26 | 4.31 | 9 | 10 | 0 | 33 | 32 | 3 | 1 | 185.2 | 196 | 96 | 89 | 73 | 184 | 9 | 16 |
| Brandon League | Min | mr | 22 | 8.55 | 1 | 1 | 1 | 19 | 0 | 0 | 0 | 40.0 | 51 | 41 | 38 | 30 | 20 | 8 | 7 |
| Brad Lidge | ChW | cl | 28 | 5.23 | 1 | 6 | 26 | 47 | 0 | 0 | 0 | 53.1 | 48 | 31 | 31 | 18 | 68 | 10 | 1 |
| Francisco Liriano* | Min | sp | 21 | 4.01 | 2 | 5 | 0 | 8 | 8 | 0 | 0 | 42.2 | 44 | 26 | 19 | 14 | 65 | 5 | 5 |
| Esteban Loaiza | LAA | sp | 33 | 5.46 | 8 | 21 | 0 | 34 | 34 | 4 | 3 | 199.1 | 248 | 130 | 121 | 51 | 159 | 17 | 16 |
| Kameron Loe | NYY | mr | 23 | 0.81 | 1 | 1 | 0 | 9 | 1 | 0 | 0 | 22.1 | 18 | 3 | 2 | 4 | 15 | 0 | 2 |
| Braden Looper | LAA | cl | 30 | 2.75 | 1 | 3 | 6 | 31 | 0 | 0 | 0 | 52.1 | 46 | 16 | 16 | 9 | 17 | 6 | 10 |
| Rodrigo Lopez | NYY | sp | 29 | 4.20 | 14 | 15 | 0 | 32 | 32 | 5 | 2 | 208.0 | 205 | 104 | 97 | 65 | 121 | 21 | 11 |
| Derek Lowe | Mtl | sp | 32 | 3.74 | 20 | 8 | 0 | 35 | 35 | 3 | 2 | 228.1 | 242 | 99 | 95 | 64 | 139 | 29 | 31 |
| Greg Maddux | Bal | sp | 39 | 4.12 | 10 | 7 | 0 | 20 | 20 | 4 | 0 | 135.1 | 158 | 70 | 62 | 17 | 69 | 9 | 17 |
| Ryan Madson | NYY | mr | 24 | 3.98 | 3 | 5 | 5 | 70 | 0 | 0 | 0 | 101.2 | 91 | 48 | 45 | 31 | 97 | 15 | 10 |
| Mike Maroth* | Tor | sp | 27 | 4.72 | 12 | 13 | 0 | 33 | 33 | 2 | 1 | 194.1 | 206 | 106 | 102 | 60 | 99 | 30 | 20 |
| Damaso Marte* | Det | mr | 30 | 5.48 | 0 | 3 | 1 | 34 | 0 | 0 | 0 | 46.0 | 48 | 28 | 28 | 30 | 49 | 3 | 8 |
| Darrell May* | ChW | mr | 33 | 5.30 | 2 | 2 | 2 | 27 | 2 | 0 | 0 | 54.1 | 60 | 35 | 32 | 15 | 34 | 12 | 5 |
| Dustin McGowan | Cle | sp | 23 | 4.26 | 4 | 3 | 0 | 13 | 11 | 0 | 0 | 67.2 | 60 | 36 | 32 | 37 | 47 | 3 | 8 |
| Brian Meadows | Mtl | mr | 29 | 5.26 | 4 | 5 | 1 | 35 | 0 | 0 | 0 | 39.1 | 47 | 23 | 23 | 5 | 24 | 2 | 5 |
| Kent Mercker* | Tex | mr | 37 | 4.12 | 3 | 1 | 0 | 16 | 0 | 0 | 0 | 19.2 | 23 | 11 | 9 | 5 | 11 | 2 | 2 |
| Wade Miller | Bos | sp | 28 | 5.23 | 3 | 10 | 0 | 17 | 17 | 0 | 0 | 93.0 | 99 | 63 | 54 | 51 | 76 | 13 | 5 |
| Brian Moehler | Det | sp | 33 | 3.48 | 2 | 0 | 0 | 19 | 0 | 0 | 0 | 54.1 | 65 | 24 | 21 | 9 | 26 | 5 | 4 |
| Matt Morris |   | sp | 30 | 3.85 | 9 | 9 | 0 | 32 | 32 | 2 | 1 | 217.2 | 214 | 103 | 93 | 41 | 121 | 29 | 21 |
| Mark Mulder* | Was | sp | 27 | 4.22 | 11 | 10 | 0 | 31 | 31 | 2 | 0 | 196.0 | 206 | 102 | 92 | 67 | 94 | 14 | 22 |
| Terry Mulholland* | LAA | mr | 42 | 3.18 | 1 | 0 | 0 | 12 | 0 | 0 | 0 | 11.1 | 8 | 4 | 4 | 5 | 4 | 0 | 1 |
| Scott Munter | NYY | mr | 25 | 4.03 | 4 | 5 | 1 | 47 | 0 | 0 | 0 | 60.1 | 68 | 31 | 27 | 34 | 21 | 4 | 14 |
| Mike Mussina | Oak | sp | 36 | 4.82 | 11 | 12 | 0 | 32 | 32 | 2 | 0 | 196.0 | 222 | 112 | 105 | 46 | 160 | 31 | 22 |
| Brett Myers | Oak | sp | 24 | 3.15 | 15 | 10 | 0 | 34 | 34 | 5 | 0 | 240.1 | 209 | 100 | 84 | 59 | 202 | 19 | 16 |
| Joe Nathan | Was | cl | 30 | 3.47 | 1 | 4 | 36 | 59 | 0 | 0 | 0 | 70.0 | 52 | 27 | 27 | 29 | 90 | 10 | 4 |
| Blaine Neal | ChW | mr | 27 | 3.65 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 12.1 | 17 | 5 | 5 | 0 | 5 | 3 | 1 |
| Hideo Nomo | Bos | sp | 36 | 7.14 | 3 | 9 | 0 | 16 | 16 | 1 | 0 | 85.2 | 111 | 77 | 68 | 59 | 43 | 8 | 3 |
| Ramon Ortiz | NYY | sp | 32 | 5.16 | 10 | 15 | 0 | 31 | 31 | 3 | 0 | 190.0 | 215 | 125 | 109 | 50 | 96 | 35 | 26 |
| Vicente Padilla | LAA | sp | 27 | 4.81 | 8 | 16 | 0 | 30 | 30 | 0 | 0 | 172.0 | 155 | 100 | 92 | 99 | 116 | 21 | 20 |
| Jonathan Papelbon | Min | mr | 24 | 4.70 | 3 | 1 | 1 | 28 | 0 | 0 | 0 | 30.2 | 36 | 17 | 16 | 18 | 32 | 1 | 3 |
| Chan Ho Park | Tor | sp | 32 | 5.75 | 6 | 6 | 0 | 21 | 21 | 0 | 0 | 103.1 | 127 | 69 | 66 | 56 | 76 | 5 | 16 |
| Jake Peavy | ChW | sp | 24 | 2.90 | 14 | 12 | 0 | 32 | 32 | 9 | 2 | 229.1 | 187 | 86 | 74 | 45 | 225 | 24 | 16 |
| Joel Peralta | Tex | mr | 29 | 5.76 | 1 | 2 | 0 | 18 | 0 | 0 | 0 | 25.0 | 26 | 17 | 16 | 10 | 22 | 4 | 2 |
| Odalis Perez* | Min | sp | 28 | 4.93 | 7 | 11 | 0 | 23 | 23 | 0 | 0 | 140.2 | 151 | 82 | 77 | 41 | 95 | 16 | 18 |
| Oliver Perez* | LAA | sp | 23 | 4.48 | 4 | 6 | 0 | 13 | 13 | 0 | 0 | 70.1 | 57 | 35 | 35 | 46 | 60 | 14 | 6 |
| Tommy Phelps* | Bos | mr | 31 | 6.23 | 1 | 3 | 0 | 26 | 0 | 0 | 0 | 43.1 | 45 | 32 | 30 | 14 | 16 | 5 | 4 |
| Joel Pineiro | Min | sp | 26 | 4.51 | 7 | 14 | 0 | 32 | 32 | 3 | 0 | 209.2 | 251 | 116 | 105 | 53 | 135 | 21 | 25 |
| Cliff Politte | ChW | mr | 31 | 1.78 | 6 | 0 | 2 | 31 | 0 | 0 | 0 | 50.2 | 30 | 10 | 10 | 8 | 38 | 6 | 3 |
| Mark Prior | KCR | sp | 24 | 3.16 | 12 | 8 | 0 | 29 | 29 | 3 | 1 | 202.0 | 165 | 78 | 71 | 58 | 215 | 20 | 10 |
| Scott Proctor | NYY | mr | 28 | 5.66 | 1 | 1 | 0 | 24 | 0 | 0 | 0 | 49.1 | 47 | 34 | 31 | 21 | 48 | 13 | 1 |
| Paul Quantrill | LAA | mr | 36 | 4.72 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 13.1 | 22 | 7 | 7 | 2 | 10 | 1 | 1 |
| Brad Radke | Mtl | sp | 32 | 4.49 | 16 | 10 | 0 | 32 | 32 | 1 | 1 | 220.1 | 248 | 114 | 110 | 35 | 144 | 38 | 8 |
| Horacio Ramirez* |   | sp | 25 | 5.10 | 11 | 16 | 0 | 34 | 34 | 2 | 0 | 213.2 | 248 | 126 | 121 | 79 | 89 | 33 | 41 |
| Chris Ray | Cle | mr | 23 | 2.09 | 0 | 3 | 2 | 39 | 0 | 0 | 0 | 47.1 | 32 | 12 | 11 | 15 | 46 | 1 | 0 |
| Steve Reed | Oak | mr | 40 | 3.38 | 0 | 0 | 0 | 9 | 0 | 0 | 0 | 10.2 | 13 | 9 | 4 | 4 | 1 | 1 | 1 |
| Chris Reitsma | Was | mr | 27 | 2.21 | 5 | 9 | 4 | 69 | 0 | 0 | 0 | 106.0 | 91 | 33 | 26 | 17 | 60 | 3 | 9 |
| Mike Remlinger* | Cle | mr | 39 | 4.26 | 1 | 3 | 1 | 54 | 0 | 0 | 0 | 50.2 | 52 | 26 | 24 | 16 | 42 | 7 | 6 |
| Chris Resop | Cle | mr | 22 | 4.82 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 9.1 | 13 | 5 | 5 | 1 | 10 | 1 | 0 |
| Anthony Reyes | KCR | mr | 23 | 2.35 | 0 | 0 | 0 | 4 | 1 | 0 | 0 | 15.1 | 9 | 4 | 4 | 5 | 11 | 2 | 1 |
| Dennys Reyes* | ChW | mr | 28 | 2.73 | 0 | 0 | 0 | 20 | 0 | 0 | 0 | 29.2 | 22 | 9 | 9 | 21 | 21 | 1 | 2 |
| Matt Riley* | Min | mr | 25 | 14.54 | 0 | 2 | 0 | 11 | 0 | 0 | 0 | 13.0 | 22 | 25 | 21 | 15 | 6 | 3 | 2 |
| Ricardo Rincon* | Mtl | mr | 35 | 3.41 | 3 | 0 | 1 | 33 | 0 | 0 | 0 | 34.1 | 35 | 15 | 13 | 20 | 19 | 7 | 5 |
| Mariano Rivera | Tor | cl | 35 | 1.00 | 7 | 0 | 33 | 68 | 0 | 0 | 0 | 90.0 | 52 | 10 | 10 | 15 | 85 | 2 | 4 |
| Fernando Rodney | Min | mr | 28 | 2.52 | 4 | 3 | 20 | 40 | 0 | 0 | 0 | 64.1 | 46 | 18 | 18 | 20 | 63 | 6 | 7 |
| Francisco Rodriguez | Tor | cl | 23 | 3.30 | 8 | 7 | 4 | 69 | 0 | 0 | 0 | 92.2 | 66 | 34 | 34 | 41 | 114 | 14 | 2 |
| Kenny Rogers* | Bal | sp | 40 | 3.67 | 15 | 8 | 0 | 30 | 30 | 4 | 0 | 188.2 | 208 | 93 | 77 | 66 | 85 | 10 | 27 |
| J.C. Romero* | Sea | mr | 29 | 4.17 | 3 | 2 | 1 | 40 | 0 | 0 | 0 | 49.2 | 38 | 25 | 23 | 36 | 34 | 3 | 3 |
| Kirk Rueter* | KCR | sp | 34 | 2.70 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 6.2 | 4 | 2 | 2 | 1 | 3 | 0 | 0 |
| Glendon Rusch* | NYY | mr | 30 | 5.79 | 1 | 1 | 0 | 18 | 0 | 0 | 0 | 37.1 | 53 | 27 | 24 | 12 | 36 | 6 | 4 |
| B.J. Ryan* | Was | cl | 29 | 1.44 | 7 | 3 | 7 | 67 | 0 | 0 | 0 | 94.0 | 53 | 17 | 15 | 32 | 118 | 6 | 5 |
| C.C. Sabathia* | KCR | sp | 24 | 2.28 | 15 | 7 | 0 | 31 | 31 | 7 | 4 | 225.1 | 187 | 63 | 57 | 69 | 196 | 13 | 20 |
| Duaner Sanchez | Mtl | mr | 25 | 4.08 | 5 | 2 | 6 | 42 | 0 | 0 | 0 | 53.0 | 46 | 26 | 24 | 25 | 50 | 4 | 4 |
| Johan Santana* | Sea | sp | 26 | 3.58 | 12 | 15 | 0 | 33 | 33 | 6 | 2 | 241.1 | 205 | 99 | 96 | 50 | 244 | 27 | 10 |
| Julio Santana | Sea | mr | 32 | 8.27 | 0 | 0 | 2 | 11 | 0 | 0 | 0 | 16.1 | 23 | 16 | 15 | 7 | 22 | 6 | 1 |
| Victor Santos | Sea | sp | 28 | 5.13 | 5 | 12 | 0 | 25 | 24 | 1 | 0 | 131.2 | 157 | 80 | 75 | 45 | 77 | 14 | 5 |
| Scott Sauerbeck* | ChW | mr | 33 | 6.63 | 2 | 1 | 1 | 21 | 0 | 0 | 0 | 19.0 | 22 | 15 | 14 | 13 | 21 | 4 | 4 |
| Joe Saunders* | Cle | sp | 24 | 5.57 | 2 | 4 | 0 | 6 | 6 | 0 | 0 | 32.1 | 35 | 21 | 20 | 19 | 12 | 8 | 6 |
| Scott Schoeneweis* | Bal | mr | 31 | 2.89 | 5 | 1 | 0 | 50 | 0 | 0 | 0 | 53.0 | 49 | 19 | 17 | 22 | 40 | 0 | 11 |
| Rudy Seanez | Tex | mr | 36 | 3.06 | 2 | 3 | 2 | 45 | 0 | 0 | 0 | 61.2 | 56 | 28 | 21 | 23 | 93 | 5 | 4 |
| Bobby Seay* | LAA | mr | 27 | 13.50 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.1 | 4 | 2 | 2 | 1 | 2 | 0 | 0 |
| Aaron Sele | Sea | sp | 35 | 6.87 | 6 | 3 | 0 | 19 | 19 | 0 | 0 | 90.1 | 130 | 71 | 69 | 26 | 39 | 16 | 5 |
| Ben Sheets | Oak | sp | 26 | 3.46 | 11 | 9 | 0 | 26 | 26 | 8 | 3 | 176.2 | 185 | 78 | 68 | 41 | 138 | 19 | 12 |
| George Sherrill* | KCR | mr | 28 | 2.70 | 1 | 1 | 1 | 25 | 0 | 0 | 0 | 30.0 | 24 | 9 | 9 | 14 | 43 | 3 | 2 |
| Brian Shouse* | Tor | mr | 36 | 3.40 | 3 | 2 | 2 | 45 | 0 | 0 | 0 | 50.1 | 52 | 22 | 19 | 24 | 26 | 6 | 8 |
| Rafael Soriano | Min | mr | 25 | 9.00 | 0 | 3 | 2 | 12 | 0 | 0 | 0 | 16.0 | 19 | 16 | 16 | 10 | 14 | 2 | 1 |
| Justin Speier | Sea | mr | 31 | 2.73 | 11 | 4 | 4 | 70 | 0 | 0 | 0 | 105.1 | 80 | 32 | 32 | 17 | 85 | 11 | 10 |
| Ryan Speier | Tor | mr | 25 | 1.35 | 0 | 0 | 1 | 4 | 0 | 0 | 0 | 6.2 | 3 | 1 | 1 | 1 | 0 | 0 | 0 |
| Mike Stanton* | Mtl | mr | 38 | 0.00 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 1.1 | 0 | 0 | 0 | 0 | 2 | 0 | 0 |
| Huston Street | NYY | cl | 21 | 1.95 | 3 | 3 | 34 | 60 | 0 | 0 | 0 | 69.1 | 40 | 16 | 15 | 24 | 61 | 6 | 8 |
| Tanyon Sturtze | Tex | mr | 34 | 4.59 | 0 | 1 | 1 | 18 | 0 | 0 | 0 | 33.1 | 34 | 18 | 17 | 11 | 10 | 5 | 3 |
| Jeff Suppan | Was | sp | 30 | 4.06 | 16 | 11 | 0 | 33 | 33 | 2 | 1 | 201.2 | 197 | 98 | 91 | 69 | 106 | 13 | 25 |
| Jack Taschner* | NYY | mr | 27 | 1.93 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 4.2 | 2 | 1 | 1 | 2 | 6 | 0 | 0 |
| Brett Tomko | NYY | sp | 32 | 5.54 | 13 | 13 | 0 | 32 | 32 | 3 | 0 | 209.2 | 236 | 135 | 129 | 57 | 136 | 33 | 15 |
| Salomon Torres | Det | mr | 33 | 2.32 | 4 | 1 | 2 | 47 | 0 | 0 | 0 | 73.2 | 50 | 21 | 19 | 27 | 50 | 4 | 6 |
| Josh Towers | Tex | sp | 28 | 3.64 | 12 | 13 | 0 | 34 | 34 | 2 | 2 | 225.0 | 235 | 103 | 91 | 28 | 130 | 18 | 17 |
| Ugueth Urbina | KCR | mr | 31 | 3.71 | 12 | 7 | 22 | 62 | 0 | 0 | 0 | 87.1 | 53 | 38 | 36 | 40 | 107 | 13 | 1 |
| Ismael Valdez | Cle | sp | 31 | 8.91 | 0 | 6 | 0 | 9 | 8 | 0 | 0 | 32.1 | 55 | 37 | 32 | 9 | 12 | 5 | 6 |
| Jose Valverde | Mtl | mr | 25 | 4.30 | 3 | 8 | 5 | 40 | 0 | 0 | 0 | 58.2 | 48 | 28 | 28 | 24 | 61 | 7 | 1 |
| Claudio Vargas | Cle | sp | 27 | 4.83 | 5 | 14 | 0 | 28 | 27 | 1 | 1 | 158.1 | 164 | 88 | 85 | 45 | 91 | 20 | 7 |
| Justin Verlander | Cle | sp | 22 | 4.96 | 2 | 3 | 0 | 6 | 6 | 1 | 0 | 32.2 | 48 | 23 | 18 | 8 | 12 | 5 | 0 |
| Luis Vizcaino | NYY | mr | 30 | 5.43 | 2 | 3 | 0 | 35 | 0 | 0 | 0 | 68.0 | 86 | 46 | 41 | 25 | 37 | 7 | 11 |
| Ryan Vogelsong | Was | mr | 27 | 3.84 | 4 | 1 | 2 | 41 | 0 | 0 | 0 | 86.2 | 80 | 39 | 37 | 45 | 44 | 4 | 16 |
| Edison Volquez | Cle | sp | 21 | 11.57 | 0 | 2 | 0 | 5 | 3 | 0 | 0 | 14.0 | 30 | 18 | 18 | 5 | 7 | 1 | 3 |
| Ryan Wagner | Bos | mr | 22 | 4.62 | 1 | 7 | 6 | 51 | 0 | 0 | 0 | 76.0 | 93 | 43 | 39 | 24 | 55 | 5 | 16 |
| Tim Wakefield | Tex | sp | 38 | 5.04 | 12 | 13 | 0 | 32 | 32 | 1 | 0 | 196.1 | 196 | 117 | 110 | 67 | 135 | 42 | 15 |
| Jamie Walker* | Mtl | mr | 33 | 6.11 | 0 | 3 | 2 | 32 | 0 | 0 | 0 | 35.1 | 47 | 31 | 24 | 17 | 17 | 5 | 3 |
| John Wasdin | Bal | mr | 32 | 3.67 | 2 | 2 | 0 | 11 | 0 | 0 | 0 | 34.1 | 30 | 14 | 14 | 10 | 15 | 4 | 3 |
| Jarrod Washburn* | Det | sp | 30 | 4.09 | 12 | 12 | 0 | 31 | 31 | 4 | 1 | 200.1 | 209 | 106 | 91 | 55 | 114 | 25 | 26 |
| Jeff Weaver | Sea | sp | 28 | 3.96 | 15 | 9 | 0 | 34 | 34 | 3 | 1 | 220.2 | 235 | 101 | 97 | 48 | 127 | 32 | 17 |
| Brandon Webb | Det | sp | 26 | 3.38 | 19 | 8 | 0 | 35 | 35 | 7 | 3 | 252.2 | 239 | 99 | 95 | 63 | 146 | 19 | 40 |
| David Wells* | Bal | sp | 42 | 5.54 | 12 | 12 | 0 | 31 | 31 | 2 | 0 | 178.2 | 240 | 127 | 110 | 30 | 107 | 19 | 30 |
| Jake Westbrook | Tex | sp | 27 | 4.36 | 13 | 14 | 0 | 34 | 34 | 2 | 2 | 221.0 | 252 | 120 | 107 | 53 | 131 | 19 | 25 |
| Dan Wheeler |   | mr | 27 | 1.79 | 8 | 3 | 20 | 66 | 0 | 0 | 0 | 85.1 | 63 | 18 | 17 | 15 | 69 | 7 | 10 |
| Rick White | Cle | mr | 36 | 4.57 | 5 | 10 | 1 | 66 | 0 | 0 | 0 | 69.0 | 84 | 38 | 35 | 23 | 35 | 4 | 9 |
| Dave Williams* | KCR | sp | 26 | 3.82 | 10 | 8 | 0 | 30 | 30 | 2 | 1 | 179.0 | 176 | 83 | 76 | 52 | 96 | 22 | 20 |
| Jerome Williams |   | sp | 23 | 4.44 | 10 | 5 | 0 | 23 | 23 | 2 | 0 | 131.2 | 134 | 72 | 65 | 46 | 67 | 13 | 21 |
| Woody Williams | ChW | sp | 38 | 4.97 | 9 | 11 | 0 | 30 | 30 | 3 | 0 | 184.2 | 198 | 103 | 102 | 57 | 115 | 37 | 11 |
| Scott Williamson | Min | mr | 29 | 4.00 | 1 | 2 | 6 | 20 | 0 | 0 | 0 | 27.0 | 31 | 12 | 12 | 9 | 31 | 7 | 2 |
| Dontrelle Willis* | Was | sp | 23 | 2.64 | 14 | 11 | 0 | 36 | 36 | 11 | 4 | 266.0 | 235 | 85 | 78 | 68 | 182 | 17 | 31 |
| C.J. Wilson* | Min | mr | 24 | 5.80 | 6 | 5 | 2 | 40 | 0 | 0 | 0 | 71.1 | 93 | 48 | 46 | 29 | 47 | 10 | 6 |
| Paul Wilson | Det | sp | 32 | 5.27 | 1 | 0 | 0 | 3 | 2 | 0 | 0 | 13.2 | 17 | 11 | 8 | 8 | 6 | 2 | 2 |
| Matt Wise | ChW | mr | 29 | 2.70 | 2 | 1 | 2 | 27 | 0 | 0 | 0 | 53.1 | 37 | 18 | 16 | 15 | 52 | 7 | 3 |
| Kerry Wood | Mtl | mr | 28 | 4.18 | 8 | 4 | 0 | 18 | 18 | 1 | 0 | 114.0 | 84 | 56 | 53 | 35 | 109 | 34 | 7 |
| Tim Worrell | ChW | mr | 37 | 3.42 | 2 | 2 | 0 | 16 | 0 | 0 | 0 | 26.1 | 27 | 10 | 10 | 8 | 19 | 0 | 0 |
| Jamey Wright | NYY | sp | 30 | 5.79 | 4 | 9 | 0 | 25 | 23 | 2 | 0 | 129.0 | 142 | 89 | 83 | 72 | 64 | 20 | 19 |
| Keiichi Yabu | Cle | mr | 36 | 3.28 | 0 | 1 | 1 | 41 | 0 | 0 | 0 | 90.2 | 88 | 36 | 33 | 27 | 58 | 3 | 10 |
| Esteban Yan | ChW | mr | 30 | 6.11 | 0 | 1 | 0 | 22 | 0 | 0 | 0 | 35.1 | 46 | 25 | 24 | 12 | 24 | 8 | 6 |
| Victor Zambrano | Det | sp | 29 | 4.53 | 8 | 12 | 0 | 24 | 24 | 1 | 0 | 143.0 | 149 | 73 | 72 | 56 | 85 | 11 | 13 |
| Barry Zito* | ChW | sp | 27 | 3.09 | 21 | 9 | 0 | 34 | 34 | 6 | 3 | 241.2 | 186 | 95 | 83 | 88 | 194 | 26 | 24 |
| Secondary |
| Name | Team | P | Age | SB | CS | IW | HBP | WP | BK | SH | SF | H/9 | BB/9 | R/9 | K/9 | HR/9 | K/BB | WHIP |
| Jeremy Accardo | ChW | mr | 23 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 2 | 11.9 | 3.2 | 15.1 | 4.3 | 3.2 | 1.3 | 1.68 |
| Jose Acevedo | ChW | mr | 27 | 2 | 1 | 0 | 3 | 0 | 0 | 0 | 0 | 9.7 | 2.0 | 12.5 | 4.0 | 2.8 | 2.0 | 1.29 |
| Jeremy Affeldt* | Bos | mr | 26 | 3 | 0 | 1 | 2 | 5 | 0 | 1 | 1 | 9.3 | 3.7 | 13.2 | 7.6 | 0.6 | 2.1 | 1.44 |
| Wilson Alvarez* | Det | mr | 35 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 13.5 | 4.5 | 18.0 | 9.0 | 0.0 | 2.0 | 2.00 |
| Brian Anderson* | KCR | sp | 33 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 14.5 | 2.1 | 16.6 | 9.3 | 3.1 | 4.5 | 1.85 |
| Matt Anderson | Min | mr | 28 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 14.3 | 9.8 | 25.5 | 4.5 | 2.3 | 0.5 | 2.67 |
| Greg Aquino | Bal | mr | 27 | 3 | 0 | 0 | 5 | 5 | 4 | 2 | 2 | 10.1 | 4.0 | 15.0 | 9.8 | 1.9 | 2.4 | 1.57 |
| Ezequiel Astacio | Min | sp | 25 | 13 | 5 | 2 | 1 | 9 | 3 | 4 | 1 | 10.6 | 1.9 | 12.5 | 7.0 | 2.3 | 3.7 | 1.39 |
| Luis Ayala | Was | mr | 27 | 1 | 1 | 1 | 10 | 0 | 0 | 1 | 2 | 10.2 | 2.0 | 13.8 | 6.2 | 0.8 | 3.2 | 1.36 |
| Manny Aybar | Bos | mr | 33 | 1 | 0 | 2 | 0 | 1 | 0 | 0 | 4 | 11.8 | 3.8 | 15.6 | 8.7 | 1.9 | 2.3 | 1.73 |
| Danys Baez | Sea | cl | 27 | 5 | 1 | 2 | 6 | 0 | 0 | 4 | 6 | 8.3 | 2.9 | 11.8 | 5.6 | 0.9 | 1.9 | 1.25 |
| James Baldwin | Oak | mr | 33 | 0 | 2 | 1 | 1 | 2 | 1 | 0 | 0 | 9.7 | 1.9 | 11.8 | 3.3 | 1.4 | 1.8 | 1.29 |
| Cliff Bartosh* | Bos | mr | 25 | 1 | 0 | 4 | 2 | 0 | 0 | 0 | 2 | 9.1 | 4.5 | 14.0 | 8.1 | 3.5 | 1.8 | 1.51 |
| Jonah Bayliss | Bos | mr | 24 | 2 | 0 | 0 | 2 | 2 | 0 | 1 | 0 | 4.4 | 4.9 | 10.2 | 6.2 | 0.9 | 1.3 | 1.03 |
| Josh Beckett | KCR | sp | 25 | 6 | 5 | 3 | 11 | 4 | 0 | 5 | 5 | 7.6 | 2.9 | 11.0 | 8.7 | 0.6 | 3.0 | 1.17 |
| Armando Benitez | ChW | cl | 32 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 5.5 | 2.8 | 8.3 | 5.2 | 1.0 | 1.9 | 0.92 |
| Joaquin Benoit | Tor | mr | 27 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 6.5 | 2.9 | 9.4 | 9.2 | 0.6 | 3.2 | 1.05 |
| Kris Benson | ChW | sp | 30 | 8 | 2 | 3 | 2 | 2 | 0 | 4 | 5 | 9.6 | 2.4 | 12.1 | 4.7 | 1.8 | 2.0 | 1.33 |
| Jason Bergmann | KCR | mr | 23 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 4.7 | 4.0 | 8.8 | 8.4 | 0.4 | 2.1 | 0.97 |
| Rafael Betancourt | Oak | mr | 30 | 4 | 0 | 3 | 3 | 0 | 0 | 5 | 2 | 7.2 | 2.3 | 9.9 | 9.2 | 0.1 | 4.0 | 1.06 |
| Jeremy Bonderman | Oak | sp | 22 | 14 | 0 | 3 | 6 | 3 | 0 | 1 | 4 | 9.5 | 3.2 | 13.0 | 6.5 | 1.2 | 2.0 | 1.42 |
| Joe Borowski | Mtl | mr | 34 | 2 | 0 | 2 | 1 | 1 | 0 | 0 | 0 | 10.3 | 1.3 | 11.8 | 4.5 | 1.3 | 3.4 | 1.29 |
| Ricky Bottalico | Bos | mr | 35 | 0 | 4 | 1 | 7 | 15 | 0 | 3 | 0 | 9.7 | 3.4 | 14.0 | 6.1 | 0.8 | 1.8 | 1.46 |
| Blaine Boyer | Det | mr | 23 | 0 | 0 | 2 | 2 | 1 | 0 | 0 | 0 | 6.5 | 3.8 | 10.9 | 8.2 | 0.8 | 2.1 | 1.15 |
| Chad Bradford | Oak | mr | 30 | 1 | 0 | 1 | 2 | 3 | 0 | 0 | 1 | 14.1 | 1.5 | 16.3 | 3.7 | 1.1 | 2.5 | 1.73 |
| Craig Breslow* | Bal | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 9.0 | 18.0 | 0.0 | 0.0 | 0.0 | 2.00 |
| Doug Brocail | Tor | mr | 38 | 10 | 1 | 8 | 5 | 7 | 0 | 1 | 7 | 9.4 | 4.5 | 14.3 | 7.7 | 0.5 | 1.7 | 1.54 |
| Jim Brower | Cle | mr | 32 | 3 | 2 | 1 | 7 | 5 | 0 | 2 | 3 | 11.8 | 4.4 | 17.5 | 5.8 | 1.2 | 1.3 | 1.80 |
| Kevin Brown | Mtl | sp | 40 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 9.0 | 3.6 | 14.4 | 9.0 | 3.6 | 2.5 | 1.40 |
| Brian Bruney | NYY | cl | 23 | 0 | 1 | 0 | 3 | 0 | 0 | 0 | 1 | 12.1 | 7.3 | 20.6 | 9.3 | 1.2 | 1.3 | 2.15 |
| Ryan Bukvich | Min | mr | 27 | 0 | 1 | 0 | 2 | 2 | 0 | 0 | 0 | 12.0 | 10.0 | 24.0 | 11.0 | 3.0 | 1.1 | 2.44 |
| Bryan Bullington | LAA | mr | 24 | 0 | 0 | 0 | 2 | 1 | 0 | 0 | 1 | 11.6 | 1.9 | 17.4 | 3.9 | 3.9 | 2.0 | 1.50 |
| Nate Bump | Det | mr | 28 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 16.8 | 5.6 | 23.3 | 6.5 | 0.9 | 1.2 | 2.48 |
| Paul Byrd | Tor | sp | 34 | 14 | 2 | 4 | 6 | 1 | 0 | 1 | 6 | 9.6 | 1.3 | 11.1 | 4.8 | 1.1 | 3.7 | 1.21 |
| Tim Byrdak* | Sea | mr | 31 | 0 | 0 | 1 | 1 | 7 | 0 | 0 | 0 | 7.4 | 6.7 | 14.4 | 11.8 | 0.4 | 1.8 | 1.56 |
| Daniel Cabrera | Cle | sp | 24 | 13 | 6 | 3 | 12 | 4 | 2 | 1 | 5 | 7.4 | 4.3 | 12.3 | 9.9 | 0.6 | 2.3 | 1.31 |
| Matt Cain | NYY | sp | 20 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 5.3 | 3.4 | 9.0 | 6.2 | 0.6 | 1.8 | 0.97 |
| Kiko Calero | Bal | mr | 30 | 10 | 0 | 4 | 1 | 1 | 0 | 1 | 2 | 8.1 | 2.9 | 11.1 | 9.5 | 1.0 | 3.3 | 1.22 |
| Shawn Camp | KCR | mr | 29 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 10.4 | 2.1 | 14.5 | 4.2 | 4.2 | 2.0 | 1.38 |
| Matt Capps | Sea | mr | 21 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 33.8 | 6.8 | 47.3 | 0.0 | 6.8 | 0.0 | 4.50 |
| Chris Capuano* | NYY | sp | 26 | 4 | 4 | 2 | 10 | 4 | 6 | 6 | 8 | 9.1 | 4.0 | 13.5 | 6.4 | 1.1 | 1.6 | 1.45 |
| Chris Carpenter | Tex | sp | 30 | 11 | 3 | 4 | 3 | 3 | 0 | 4 | 3 | 8.1 | 2.2 | 10.4 | 8.5 | 1.0 | 3.8 | 1.15 |
| Hector Carrasco | LAA | mr | 35 | 9 | 3 | 6 | 7 | 3 | 0 | 3 | 7 | 6.9 | 3.5 | 11.0 | 7.1 | 1.0 | 2.0 | 1.15 |
| Lance Carter | Mtl | mr | 30 | 2 | 4 | 1 | 2 | 0 | 0 | 0 | 2 | 8.8 | 2.6 | 11.7 | 4.0 | 0.9 | 1.5 | 1.27 |
| Marcos Carvajal | KCR | mr | 20 | 2 | 2 | 0 | 2 | 9 | 0 | 1 | 0 | 8.0 | 3.8 | 12.1 | 7.4 | 1.1 | 1.9 | 1.32 |
| Frank Castillo | KCR | sp | 36 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.5 | 6.4 | 15.9 | 9.5 | 1.6 | 1.5 | 1.76 |
| Gustavo Chacin* | Bal | sp | 24 | 11 | 1 | 3 | 11 | 3 | 0 | 6 | 5 | 10.0 | 2.8 | 13.3 | 6.3 | 1.0 | 2.2 | 1.42 |
| Shawn Chacon | Det | sp | 27 | 11 | 8 | 1 | 11 | 5 | 1 | 3 | 6 | 7.9 | 3.1 | 11.5 | 3.6 | 0.8 | 1.2 | 1.22 |
| Bruce Chen* | Cle | sp | 28 | 8 | 3 | 2 | 7 | 2 | 3 | 1 | 3 | 8.3 | 3.3 | 11.9 | 5.8 | 1.1 | 1.7 | 1.29 |
| Jason Christiansen* | Mtl | mr | 35 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1.6 | 0.0 | 1.6 | 1.6 | 0.0 | 99.0 | 0.18 |
| Vinnie Chulk | Tex | mr | 26 | 1 | 0 | 0 | 1 | 4 | 0 | 0 | 0 | 9.3 | 4.0 | 13.5 | 5.0 | 1.0 | 1.3 | 1.48 |
| Brandon Claussen* | LAA | sp | 26 | 33 | 9 | 0 | 12 | 0 | 4 | 4 | 12 | 9.7 | 2.9 | 13.1 | 5.9 | 1.0 | 2.1 | 1.39 |
| Jesus Colome | Cle | mr | 27 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 1 | 16.4 | 2.9 | 19.3 | 6.8 | 0.0 | 2.3 | 2.14 |
| Bartolo Colon | Sea | sp | 32 | 6 | 5 | 1 | 2 | 4 | 0 | 4 | 8 | 9.4 | 2.3 | 11.8 | 6.4 | 1.1 | 2.8 | 1.30 |
| Brian Cooper | Tor | mr | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.0 | 3.0 | 9.0 | 3.0 | 0.0 | 1.0 | 1.00 |
| Francisco Cordero | Tex | cl | 30 | 1 | 0 | 0 | 2 | 0 | 0 | 2 | 2 | 8.8 | 4.5 | 13.7 | 12.1 | 0.8 | 2.7 | 1.48 |
| Doug Creek* | Was | mr | 36 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 10.3 | 2.4 | 12.7 | 7.1 | 1.6 | 3.0 | 1.41 |
| Juan Cruz | Min | mr | 26 | 4 | 2 | 0 | 16 | 7 | 1 | 0 | 3 | 12.7 | 5.0 | 19.2 | 11.4 | 2.1 | 2.3 | 1.96 |
| Jason Davis | KCR | mr | 25 | 5 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 9.2 | 2.6 | 12.2 | 5.9 | 0.4 | 2.3 | 1.32 |
| Zach Day | Bal | mr | 27 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 9.8 | 8.6 | 18.4 | 4.6 | 1.1 | 0.5 | 2.04 |
| Valerio de los Santos* | KCR | mr | 32 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.8 | 6.8 | 13.5 | 6.8 | 0.0 | 1.0 | 1.50 |
| Mike DeJean | Tor | mr | 34 | 6 | 2 | 2 | 8 | 7 | 0 | 2 | 2 | 9.0 | 3.8 | 13.7 | 6.4 | 0.9 | 1.7 | 1.42 |
| Manny Delcarmen | Cle | mr | 23 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 13.5 | 5.3 | 19.5 | 9.0 | 1.5 | 1.7 | 2.08 |
| Ryan Dempster | LAA | cl | 28 | 7 | 0 | 3 | 2 | 0 | 0 | 4 | 3 | 9.1 | 4.3 | 13.7 | 7.8 | 0.0 | 1.8 | 1.49 |
| Elmer Dessens | Sea | mr | 34 | 4 | 4 | 1 | 3 | 1 | 0 | 2 | 1 | 8.7 | 1.9 | 10.8 | 4.5 | 0.8 | 2.4 | 1.18 |
| Joey Devine | Bos | mr | 21 | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 10.8 | 3.8 | 14.6 | 3.2 | 3.2 | 0.8 | 1.62 |
| R.A. Dickey | KCR | mr | 30 | 2 | 2 | 0 | 3 | 0 | 0 | 0 | 0 | 9.5 | 6.5 | 17.1 | 6.8 | 1.9 | 1.1 | 1.77 |
| Craig Dingman | Det | mr | 31 | 2 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 8.2 | 2.0 | 10.6 | 7.8 | 1.2 | 4.0 | 1.13 |
| Juan Dominguez | Min | mr | 25 | 8 | 4 | 1 | 4 | 5 | 0 | 2 | 4 | 10.6 | 2.9 | 13.8 | 5.1 | 1.3 | 1.8 | 1.50 |
| Octavio Dotel | Oak | cl | 31 | 4 | 4 | 2 | 2 | 2 | 0 | 2 | 1 | 6.7 | 6.0 | 13.3 | 7.3 | 1.0 | 1.2 | 1.41 |
| Scott Downs* | LAA | sp | 29 | 0 | 0 | 1 | 4 | 4 | 0 | 0 | 0 | 8.1 | 3.6 | 12.3 | 7.8 | 0.9 | 2.2 | 1.30 |
| Zach Duke* | Tor | sp | 22 | 1 | 1 | 4 | 5 | 1 | 0 | 1 | 1 | 7.6 | 2.4 | 10.4 | 7.6 | 0.4 | 3.1 | 1.12 |
| Adam Eaton | LAA | sp | 27 | 13 | 4 | 6 | 12 | 5 | 0 | 1 | 7 | 9.7 | 2.7 | 13.2 | 6.4 | 1.2 | 2.3 | 1.39 |
| Scott Erickson | KCR | mr | 37 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6.8 | 2.5 | 9.3 | 0.8 | 0.8 | 0.3 | 1.03 |
| Kelvim Escobar | Min | mr | 29 | 6 | 2 | 7 | 2 | 5 | 0 | 3 | 2 | 7.0 | 3.3 | 10.6 | 8.9 | 0.9 | 2.7 | 1.15 |
| Mike Esposito | Bos | sp | 23 | 2 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 13.0 | 4.2 | 17.1 | 1.6 | 1.0 | 0.4 | 1.90 |
| Shawn Estes* | Tor | sp | 32 | 7 | 2 | 3 | 3 | 2 | 0 | 4 | 1 | 9.1 | 3.8 | 13.1 | 3.2 | 1.3 | 0.8 | 1.44 |
| Seth Etherton | ChW | sp | 28 | 3 | 0 | 3 | 1 | 1 | 4 | 0 | 0 | 6.3 | 4.2 | 10.6 | 4.4 | 1.1 | 1.0 | 1.16 |
| Dana Eveland* | Cle | mr | 21 | 3 | 0 | 2 | 0 | 1 | 0 | 0 | 1 | 10.3 | 4.6 | 14.9 | 6.6 | 0.2 | 1.5 | 1.65 |
| Scott Eyre* | Oak | mr | 33 | 2 | 1 | 0 | 5 | 6 | 0 | 0 | 7 | 6.8 | 3.1 | 10.5 | 7.9 | 1.0 | 2.5 | 1.11 |
| Kyle Farnsworth | Det | mr | 29 | 9 | 3 | 0 | 7 | 4 | 0 | 2 | 2 | 6.1 | 3.3 | 10.1 | 12.8 | 0.4 | 3.9 | 1.04 |
| Jeff Fassero* | Tex | mr | 42 | 2 | 0 | 2 | 3 | 3 | 0 | 2 | 4 | 9.7 | 3.2 | 13.3 | 5.9 | 0.8 | 1.8 | 1.43 |
| Ron Flores* | KCR | mr | 25 | 1 | 0 | 2 | 0 | 1 | 0 | 1 | 0 | 10.8 | 1.8 | 12.6 | 5.4 | 1.8 | 3.0 | 1.40 |
| Josh Fogg | Bal | sp | 28 | 6 | 6 | 0 | 4 | 0 | 0 | 1 | 4 | 10.5 | 2.3 | 13.2 | 4.1 | 1.6 | 1.8 | 1.42 |
| Keith Foulke | Oak | cl | 32 | 3 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 14.4 | 3.8 | 18.5 | 5.6 | 3.8 | 1.5 | 2.02 |
| Jeff Francis* | Bos | sp | 24 | 8 | 4 | 2 | 3 | 2 | 0 | 3 | 5 | 9.3 | 3.8 | 13.2 | 5.7 | 0.7 | 1.5 | 1.45 |
| Brian Fuentes* | Bal | cl | 29 | 1 | 2 | 1 | 8 | 7 | 0 | 1 | 4 | 3.9 | 2.7 | 7.7 | 10.6 | 0.1 | 3.9 | 0.74 |
| Jairo Garcia | Bos | mr | 22 | 0 | 0 | 1 | 0 | 3 | 0 | 1 | 1 | 19.6 | 12.3 | 31.9 | 2.5 | 0.0 | 0.2 | 3.55 |
| Jon Garland | Mtl | sp | 25 | 5 | 2 | 1 | 6 | 0 | 0 | 2 | 4 | 8.3 | 2.0 | 10.9 | 5.3 | 0.8 | 2.7 | 1.15 |
| Dave Gassner* | Sea | sp | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11.7 | 2.7 | 14.4 | 2.7 | 0.9 | 1.0 | 1.60 |
| Geoff Geary | LAA | mr | 28 | 5 | 4 | 1 | 4 | 2 | 0 | 0 | 0 | 10.2 | 3.9 | 14.5 | 5.4 | 0.7 | 1.4 | 1.56 |
| Matt Ginter | KCR | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 27.0 | 0.0 | 27.0 | 0.0 | 0.0 | 0.0 | 3.00 |
| Gary Glover | KCR | sp | 28 | 3 | 2 | 0 | 2 | 3 | 0 | 2 | 4 | 11.3 | 2.4 | 13.9 | 9.4 | 1.1 | 4.0 | 1.51 |
| Jimmy Gobble* | Cle | mr | 23 | 9 | 5 | 1 | 6 | 5 | 0 | 0 | 6 | 11.7 | 5.8 | 17.9 | 6.9 | 1.1 | 1.2 | 1.94 |
| Jeremi Gonzalez | Oak | mr | 30 | 6 | 1 | 1 | 6 | 1 | 0 | 1 | 4 | 11.1 | 2.3 | 14.3 | 6.1 | 1.1 | 2.7 | 1.49 |
| Tom Gordon | Bal | mr | 37 | 7 | 1 | 4 | 1 | 4 | 3 | 0 | 1 | 5.7 | 2.5 | 8.3 | 8.0 | 0.8 | 3.2 | 0.92 |
| John Grabow* | KCR | mr | 26 | 2 | 3 | 1 | 2 | 1 | 0 | 0 | 4 | 8.5 | 3.1 | 11.9 | 7.7 | 0.7 | 2.5 | 1.29 |
| Danny Graves | KCR | cl | 31 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 33.8 | 20.3 | 54.0 | 0.0 | 6.8 | 0.0 | 6.00 |
| Zack Greinke | Bos | sp | 21 | 15 | 6 | 4 | 10 | 4 | 2 | 3 | 9 | 12.8 | 3.5 | 16.9 | 4.8 | 1.2 | 1.4 | 1.81 |
| Buddy Groom* | Sea | mr | 39 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 18.0 | 0.0 | 18.0 | 0.0 | 0.0 | 0.0 | 2.00 |
| Kevin Gryboski | Bal | mr | 31 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 9.8 | 5.3 | 16.5 | 3.0 | 0.0 | 0.6 | 1.67 |
| Eddie Guardado* |   | cl | 34 | 3 | 0 | 3 | 3 | 1 | 0 | 2 | 5 | 7.0 | 2.1 | 9.4 | 7.8 | 0.8 | 3.8 | 1.00 |
| John Halama* | KCR | mr | 33 | 3 | 0 | 1 | 6 | 0 | 0 | 1 | 0 | 10.6 | 2.3 | 14.0 | 4.5 | 0.4 | 1.9 | 1.44 |
| Brad Halsey* | Mtl | sp | 24 | 6 | 1 | 1 | 5 | 1 | 0 | 1 | 6 | 9.0 | 2.5 | 11.9 | 4.9 | 1.3 | 2.0 | 1.28 |
| Mike Hampton* | Det | sp | 32 | 3 | 2 | 0 | 0 | 1 | 0 | 1 | 3 | 9.4 | 4.1 | 13.6 | 3.3 | 0.8 | 0.8 | 1.51 |
| Craig Hansen | Bos | mr | 21 | 0 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 13.2 | 2.8 | 15.9 | 3.5 | 2.8 | 1.3 | 1.77 |
| Aaron Harang | Was | sp | 27 | 6 | 4 | 5 | 8 | 6 | 0 | 1 | 2 | 7.4 | 2.5 | 10.2 | 6.9 | 0.6 | 2.8 | 1.09 |
| Chad Harville | Sea | mr | 28 | 1 | 1 | 0 | 3 | 6 | 0 | 0 | 1 | 8.5 | 4.8 | 13.8 | 7.1 | 1.2 | 1.5 | 1.47 |
| Shigetoshi Hasegawa | LAA | mr | 36 | 1 | 1 | 1 | 4 | 0 | 0 | 0 | 6 | 8.8 | 2.7 | 11.7 | 4.5 | 0.6 | 1.7 | 1.27 |
| LaTroy Hawkins | Cle | mr | 32 | 3 | 2 | 1 | 0 | 1 | 0 | 1 | 2 | 12.7 | 2.3 | 15.0 | 6.5 | 0.8 | 2.8 | 1.67 |
| Aaron Heilman | Oak | mr | 26 | 11 | 5 | 1 | 4 | 2 | 1 | 1 | 4 | 7.2 | 2.8 | 10.2 | 8.5 | 0.9 | 3.1 | 1.11 |
| Mark Hendrickson* | LAA | sp | 31 | 10 | 3 | 5 | 4 | 2 | 1 | 0 | 6 | 12.0 | 2.9 | 15.2 | 4.7 | 1.3 | 1.6 | 1.65 |
| Clay Hensley | Bal | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.7 | 3.5 | 5.2 | 7.0 | 0.9 | 2.0 | 0.58 |
| Dustin Hermanson | Bal | cl | 32 | 1 | 0 | 2 | 5 | 7 | 0 | 2 | 3 | 7.6 | 2.9 | 11.1 | 6.1 | 1.1 | 2.1 | 1.17 |
| Felix Hernandez | Min | sp | 19 | 10 | 2 | 1 | 3 | 4 | 0 | 1 | 0 | 6.5 | 3.1 | 9.9 | 9.8 | 0.4 | 3.2 | 1.07 |
| Livan Hernandez | Was | sp | 30 | 17 | 7 | 3 | 14 | 1 | 1 | 3 | 5 | 12.1 | 2.9 | 15.7 | 5.6 | 1.0 | 1.9 | 1.67 |
| Orlando Hernandez | Tor | sp | 35 | 14 | 2 | 2 | 19 | 5 | 1 | 7 | 2 | 9.1 | 3.3 | 13.6 | 7.5 | 1.2 | 2.3 | 1.38 |
| Roberto Hernandez | Tex | mr | 40 | 4 | 3 | 1 | 1 | 2 | 0 | 3 | 4 | 8.2 | 3.2 | 11.6 | 7.4 | 0.6 | 2.3 | 1.27 |
| Runelvys Hernandez | ChW | sp | 27 | 6 | 4 | 3 | 10 | 3 | 0 | 4 | 5 | 10.1 | 4.7 | 15.4 | 5.4 | 1.3 | 1.1 | 1.65 |
| Trevor Hoffman | Det | cl | 37 | 1 | 1 | 2 | 2 | 2 | 0 | 0 | 0 | 7.0 | 1.8 | 9.0 | 9.8 | 0.4 | 5.5 | 0.97 |
| D.J. Houlton | KCR | sp | 25 | 3 | 1 | 0 | 6 | 1 | 0 | 1 | 2 | 14.9 | 5.4 | 21.4 | 5.6 | 2.5 | 1.0 | 2.26 |
| J.P. Howell* |   | sp | 22 | 7 | 0 | 3 | 1 | 7 | 0 | 2 | 1 | 8.3 | 5.1 | 13.6 | 7.9 | 1.2 | 1.6 | 1.49 |
| Luke Hudson | Was | sp | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 9.0 | 18.0 | 9.0 | 0.0 | 1.0 | 2.00 |
| Tim Hudson | Det | sp | 29 | 11 | 2 | 3 | 11 | 3 | 0 | 1 | 4 | 8.9 | 2.3 | 11.7 | 4.7 | 1.1 | 2.0 | 1.25 |
| Kazuhisa Ishii* | Oak | sp | 31 | 8 | 2 | 1 | 9 | 1 | 0 | 2 | 2 | 10.2 | 3.9 | 15.0 | 4.6 | 1.8 | 1.2 | 1.57 |
| Jason Isringhausen | Sea | cl | 32 | 5 | 2 | 0 | 2 | 2 | 0 | 2 | 4 | 6.6 | 2.3 | 9.2 | 7.3 | 0.7 | 3.2 | 0.99 |
| Edwin Jackson | Min | sp | 21 | 6 | 0 | 0 | 4 | 2 | 1 | 2 | 5 | 10.6 | 5.1 | 16.6 | 4.1 | 1.0 | 0.8 | 1.75 |
| Chuck James* | Bos | mr | 23 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 6.5 | 5.4 | 11.9 | 4.3 | 2.2 | 0.8 | 1.32 |
| Bobby Jenks | KCR | mr | 24 | 0 | 1 | 1 | 0 | 4 | 0 | 1 | 3 | 7.0 | 3.1 | 10.2 | 12.4 | 0.3 | 3.9 | 1.13 |
| Jason Johnson | Tex | sp | 31 | 9 | 2 | 0 | 2 | 23 | 0 | 3 | 4 | 9.9 | 2.3 | 12.4 | 4.1 | 1.1 | 1.7 | 1.36 |
| Tyler Johnson* | Sea | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 0.0 | 9.0 | 9.0 | 0.0 | 99.0 | 1.00 |
| Jorge Julio | Cle | mr | 26 | 4 | 1 | 1 | 1 | 6 | 0 | 4 | 0 | 11.5 | 2.8 | 14.5 | 10.2 | 1.4 | 3.7 | 1.59 |
| Scott Kazmir* | Bos | sp | 21 | 17 | 4 | 4 | 5 | 5 | 1 | 4 | 5 | 7.5 | 4.8 | 12.6 | 8.3 | 0.8 | 1.7 | 1.37 |
| Joe Kennedy* | Min | sp | 26 | 15 | 3 | 4 | 10 | 9 | 2 | 5 | 5 | 11.8 | 3.1 | 15.5 | 5.6 | 1.0 | 1.8 | 1.66 |
| Byung-Hyun Kim | LAA | sp | 26 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 8.7 | 4.1 | 13.7 | 5.9 | 0.5 | 1.4 | 1.42 |
| Steve Kline* | Cle | mr | 32 | 0 | 1 | 0 | 2 | 2 | 1 | 0 | 1 | 11.6 | 2.8 | 14.9 | 7.2 | 2.6 | 2.6 | 1.60 |
| Dae-Sung Koo* | Sea | mr | 35 | 0 | 1 | 1 | 0 | 1 | 0 | 3 | 2 | 8.0 | 2.6 | 10.6 | 8.0 | 0.7 | 3.1 | 1.18 |
| Mike Koplove | Tor | mr | 28 | 0 | 1 | 2 | 5 | 1 | 0 | 1 | 2 | 7.7 | 3.0 | 11.7 | 6.0 | 0.8 | 2.0 | 1.20 |
| Hong-Chih Kuo* | Bos | mr | 23 | 2 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 7.5 | 3.2 | 10.7 | 12.2 | 2.0 | 3.8 | 1.19 |
| John Lackey | Bal | sp | 26 | 8 | 4 | 0 | 10 | 25 | 0 | 3 | 4 | 9.5 | 3.5 | 13.5 | 8.9 | 0.4 | 2.5 | 1.45 |
| Brandon League | Min | mr | 22 | 3 | 1 | 0 | 2 | 6 | 0 | 0 | 1 | 11.5 | 6.8 | 18.7 | 4.5 | 1.8 | 0.7 | 2.02 |
| Brad Lidge | ChW | cl | 28 | 2 | 0 | 0 | 2 | 5 | 0 | 1 | 1 | 8.1 | 3.0 | 11.5 | 11.5 | 1.7 | 3.8 | 1.24 |
| Francisco Liriano* | Min | sp | 21 | 4 | 2 | 0 | 1 | 0 | 0 | 0 | 1 | 9.3 | 3.0 | 12.4 | 13.7 | 1.1 | 4.6 | 1.36 |
| Esteban Loaiza | LAA | sp | 33 | 22 | 4 | 3 | 6 | 4 | 0 | 3 | 6 | 11.2 | 2.3 | 13.8 | 7.2 | 0.8 | 3.1 | 1.50 |
| Kameron Loe | NYY | mr | 23 | 0 | 2 | 0 | 2 | 0 | 0 | 0 | 2 | 7.3 | 1.6 | 9.7 | 6.0 | 0.0 | 3.8 | 0.99 |
| Braden Looper | LAA | cl | 30 | 1 | 0 | 4 | 6 | 0 | 1 | 0 | 2 | 7.9 | 1.5 | 10.5 | 2.9 | 1.0 | 1.9 | 1.05 |
| Rodrigo Lopez | NYY | sp | 29 | 8 | 6 | 1 | 9 | 2 | 1 | 6 | 2 | 8.9 | 2.8 | 12.1 | 5.2 | 0.9 | 1.9 | 1.30 |
| Derek Lowe | Mtl | sp | 32 | 20 | 6 | 9 | 6 | 6 | 4 | 6 | 4 | 9.5 | 2.5 | 12.3 | 5.5 | 1.1 | 2.2 | 1.34 |
| Greg Maddux | Bal | sp | 39 | 11 | 8 | 0 | 7 | 4 | 0 | 3 | 0 | 10.5 | 1.1 | 12.1 | 4.6 | 0.6 | 4.1 | 1.29 |
| Ryan Madson | NYY | mr | 24 | 1 | 1 | 4 | 6 | 3 | 1 | 2 | 3 | 8.1 | 2.7 | 11.3 | 8.6 | 1.3 | 3.1 | 1.20 |
| Mike Maroth* | Tor | sp | 27 | 10 | 7 | 6 | 16 | 3 | 0 | 5 | 8 | 9.5 | 2.8 | 13.1 | 4.6 | 1.4 | 1.6 | 1.37 |
| Damaso Marte* | Det | mr | 30 | 4 | 0 | 0 | 3 | 3 | 4 | 1 | 1 | 9.4 | 5.9 | 15.8 | 9.6 | 0.6 | 1.6 | 1.70 |
| Darrell May* | ChW | mr | 33 | 2 | 1 | 3 | 1 | 0 | 0 | 0 | 4 | 9.9 | 2.5 | 12.6 | 5.6 | 2.0 | 2.3 | 1.38 |
| Dustin McGowan | Cle | sp | 23 | 9 | 3 | 1 | 11 | 2 | 0 | 0 | 1 | 8.0 | 4.9 | 14.4 | 6.3 | 0.4 | 1.3 | 1.43 |
| Brian Meadows | Mtl | mr | 29 | 2 | 1 | 0 | 0 | 3 | 0 | 0 | 3 | 10.8 | 1.1 | 11.9 | 5.5 | 0.5 | 4.8 | 1.32 |
| Kent Mercker* | Tex | mr | 37 | 1 | 3 | 0 | 1 | 2 | 0 | 0 | 1 | 10.5 | 2.3 | 13.3 | 5.0 | 0.9 | 2.2 | 1.42 |
| Wade Miller | Bos | sp | 28 | 11 | 2 | 0 | 3 | 3 | 0 | 0 | 3 | 9.6 | 4.9 | 14.8 | 7.4 | 1.3 | 1.5 | 1.61 |
| Brian Moehler | Det | sp | 33 | 4 | 0 | 0 | 2 | 1 | 0 | 0 | 3 | 10.8 | 1.5 | 12.6 | 4.3 | 0.8 | 2.9 | 1.36 |
| Matt Morris |   | sp | 30 | 6 | 4 | 2 | 9 | 1 | 0 | 1 | 3 | 8.8 | 1.7 | 10.9 | 5.0 | 1.2 | 3.0 | 1.17 |
| Mark Mulder* | Was | sp | 27 | 4 | 3 | 7 | 8 | 5 | 0 | 1 | 3 | 9.5 | 3.1 | 12.9 | 4.3 | 0.6 | 1.4 | 1.39 |
| Terry Mulholland* | LAA | mr | 42 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 6.4 | 4.0 | 10.3 | 3.2 | 0.0 | 0.8 | 1.15 |
| Scott Munter | NYY | mr | 25 | 6 | 0 | 7 | 2 | 4 | 0 | 0 | 1 | 10.1 | 5.1 | 15.5 | 3.1 | 0.6 | 0.6 | 1.69 |
| Mike Mussina | Oak | sp | 36 | 15 | 5 | 2 | 10 | 3 | 0 | 3 | 4 | 10.2 | 2.1 | 12.8 | 7.3 | 1.4 | 3.5 | 1.37 |
| Brett Myers | Oak | sp | 24 | 19 | 7 | 2 | 13 | 3 | 3 | 4 | 9 | 7.8 | 2.2 | 10.5 | 7.6 | 0.7 | 3.4 | 1.12 |
| Joe Nathan | Was | cl | 30 | 3 | 2 | 0 | 3 | 0 | 0 | 0 | 4 | 6.7 | 3.7 | 10.8 | 11.6 | 1.3 | 3.1 | 1.16 |
| Blaine Neal | ChW | mr | 27 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 12.4 | 0.0 | 12.4 | 3.6 | 2.2 | 99.0 | 1.38 |
| Hideo Nomo | Bos | sp | 36 | 5 | 2 | 0 | 3 | 2 | 0 | 0 | 7 | 11.7 | 6.2 | 18.2 | 4.5 | 0.8 | 0.7 | 1.98 |
| Ramon Ortiz | NYY | sp | 32 | 6 | 6 | 0 | 7 | 4 | 4 | 3 | 9 | 10.2 | 2.4 | 12.9 | 4.5 | 1.7 | 1.9 | 1.39 |
| Vicente Padilla | LAA | sp | 27 | 10 | 4 | 6 | 13 | 1 | 0 | 5 | 4 | 8.1 | 5.2 | 14.0 | 6.1 | 1.1 | 1.2 | 1.48 |
| Jonathan Papelbon | Min | mr | 24 | 1 | 0 | 0 | 3 | 1 | 0 | 0 | 6 | 10.6 | 5.3 | 16.7 | 9.4 | 0.3 | 1.8 | 1.76 |
| Chan Ho Park | Tor | sp | 32 | 6 | 1 | 6 | 7 | 4 | 0 | 4 | 2 | 11.1 | 4.9 | 16.5 | 6.6 | 0.4 | 1.4 | 1.77 |
| Jake Peavy | ChW | sp | 24 | 10 | 2 | 3 | 6 | 2 | 1 | 3 | 5 | 7.3 | 1.8 | 9.3 | 8.8 | 0.9 | 5.0 | 1.01 |
| Joel Peralta | Tex | mr | 29 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 9.4 | 3.6 | 13.3 | 7.9 | 1.4 | 2.2 | 1.44 |
| Odalis Perez* | Min | sp | 28 | 5 | 3 | 1 | 4 | 5 | 0 | 5 | 7 | 9.7 | 2.6 | 12.5 | 6.1 | 1.0 | 2.3 | 1.36 |
| Oliver Perez* | LAA | sp | 23 | 1 | 2 | 1 | 1 | 3 | 0 | 1 | 1 | 7.3 | 5.9 | 13.3 | 7.7 | 1.8 | 1.3 | 1.46 |
| Tommy Phelps* | Bos | mr | 31 | 0 | 0 | 0 | 10 | 2 | 0 | 0 | 0 | 9.3 | 2.9 | 14.3 | 3.3 | 1.0 | 1.1 | 1.36 |
| Joel Pineiro | Min | sp | 26 | 19 | 6 | 1 | 5 | 8 | 2 | 6 | 4 | 10.8 | 2.3 | 13.3 | 5.8 | 0.9 | 2.5 | 1.45 |
| Cliff Politte | ChW | mr | 31 | 2 | 0 | 0 | 3 | 1 | 0 | 2 | 0 | 5.3 | 1.4 | 7.3 | 6.8 | 1.1 | 4.8 | 0.75 |
| Mark Prior | KCR | sp | 24 | 6 | 3 | 1 | 6 | 3 | 2 | 1 | 6 | 7.4 | 2.6 | 10.2 | 9.6 | 0.9 | 3.7 | 1.10 |
| Scott Proctor | NYY | mr | 28 | 4 | 1 | 3 | 0 | 4 | 2 | 0 | 3 | 8.6 | 3.8 | 12.4 | 8.8 | 2.4 | 2.3 | 1.38 |
| Paul Quantrill | LAA | mr | 36 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 14.8 | 1.3 | 17.5 | 6.8 | 0.7 | 5.0 | 1.80 |
| Brad Radke | Mtl | sp | 32 | 13 | 3 | 10 | 10 | 2 | 0 | 6 | 3 | 10.1 | 1.4 | 12.0 | 5.9 | 1.6 | 4.1 | 1.28 |
| Horacio Ramirez* |   | sp | 25 | 14 | 9 | 6 | 4 | 1 | 0 | 2 | 5 | 10.4 | 3.3 | 13.9 | 3.7 | 1.4 | 1.1 | 1.53 |
| Chris Ray | Cle | mr | 23 | 3 | 1 | 2 | 0 | 1 | 1 | 1 | 1 | 6.1 | 2.9 | 8.9 | 8.7 | 0.2 | 3.1 | 0.99 |
| Steve Reed | Oak | mr | 40 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 11.0 | 3.4 | 14.3 | 0.8 | 0.8 | 0.3 | 1.59 |
| Chris Reitsma | Was | mr | 27 | 3 | 1 | 1 | 1 | 4 | 0 | 3 | 7 | 7.7 | 1.4 | 9.3 | 5.1 | 0.3 | 3.5 | 1.02 |
| Mike Remlinger* | Cle | mr | 39 | 1 | 0 | 2 | 1 | 2 | 0 | 2 | 2 | 9.2 | 2.8 | 12.3 | 7.5 | 1.2 | 2.6 | 1.34 |
| Chris Resop | Cle | mr | 22 | 0 | 1 | 0 | 0 | 5 | 0 | 0 | 0 | 12.5 | 1.0 | 13.5 | 9.6 | 1.0 | 10.0 | 1.50 |
| Anthony Reyes | KCR | mr | 23 | 1 | 1 | 0 | 0 | 2 | 0 | 1 | 0 | 5.3 | 2.9 | 8.2 | 6.5 | 1.2 | 2.2 | 0.91 |
| Dennys Reyes* | ChW | mr | 28 | 2 | 0 | 2 | 1 | 2 | 1 | 1 | 1 | 6.7 | 6.4 | 13.3 | 6.4 | 0.3 | 1.0 | 1.45 |
| Matt Riley* | Min | mr | 25 | 1 | 0 | 2 | 1 | 2 | 0 | 1 | 1 | 15.2 | 10.4 | 26.3 | 4.2 | 2.1 | 0.4 | 2.85 |
| Ricardo Rincon* | Mtl | mr | 35 | 1 | 2 | 1 | 0 | 2 | 0 | 0 | 1 | 9.2 | 5.2 | 14.4 | 5.0 | 1.8 | 0.9 | 1.60 |
| Mariano Rivera | Tor | cl | 35 | 5 | 2 | 2 | 6 | 0 | 0 | 0 | 2 | 5.2 | 1.5 | 7.3 | 8.5 | 0.2 | 5.7 | 0.74 |
| Fernando Rodney | Min | mr | 28 | 5 | 1 | 2 | 1 | 3 | 0 | 2 | 0 | 6.4 | 2.8 | 9.4 | 8.8 | 0.8 | 3.2 | 1.03 |
| Francisco Rodriguez | Tor | cl | 23 | 4 | 1 | 6 | 1 | 8 | 0 | 3 | 4 | 6.4 | 4.0 | 10.5 | 11.1 | 1.4 | 2.8 | 1.15 |
| Kenny Rogers* | Bal | sp | 40 | 10 | 1 | 3 | 6 | 0 | 0 | 2 | 7 | 9.9 | 3.1 | 13.4 | 4.1 | 0.5 | 1.3 | 1.45 |
| J.C. Romero* | Sea | mr | 29 | 2 | 0 | 3 | 6 | 2 | 0 | 1 | 2 | 6.9 | 6.5 | 14.5 | 6.2 | 0.5 | 0.9 | 1.49 |
| Kirk Rueter* | KCR | sp | 34 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.4 | 1.3 | 6.8 | 4.0 | 0.0 | 3.0 | 0.75 |
| Glendon Rusch* | NYY | mr | 30 | 2 | 0 | 1 | 2 | 0 | 0 | 1 | 3 | 12.8 | 2.9 | 16.2 | 8.7 | 1.4 | 3.0 | 1.74 |
| B.J. Ryan* | Was | cl | 29 | 6 | 0 | 3 | 6 | 7 | 0 | 0 | 3 | 5.1 | 3.1 | 8.7 | 11.3 | 0.6 | 3.7 | 0.90 |
| C.C. Sabathia* | KCR | sp | 24 | 9 | 4 | 0 | 9 | 5 | 0 | 5 | 7 | 7.5 | 2.8 | 10.6 | 7.8 | 0.5 | 2.8 | 1.14 |
| Duaner Sanchez | Mtl | mr | 25 | 3 | 1 | 4 | 1 | 4 | 1 | 0 | 2 | 7.8 | 4.2 | 12.2 | 8.5 | 0.7 | 2.0 | 1.34 |
| Johan Santana* | Sea | sp | 26 | 7 | 1 | 2 | 6 | 10 | 0 | 8 | 4 | 7.6 | 1.9 | 9.7 | 9.1 | 1.0 | 4.9 | 1.06 |
| Julio Santana | Sea | mr | 32 | 1 | 0 | 0 | 0 | 2 | 0 | 1 | 0 | 12.7 | 3.9 | 16.5 | 12.1 | 3.3 | 3.1 | 1.84 |
| Victor Santos | Sea | sp | 28 | 13 | 5 | 2 | 3 | 8 | 0 | 4 | 4 | 10.7 | 3.1 | 14.0 | 5.3 | 1.0 | 1.7 | 1.53 |
| Scott Sauerbeck* | ChW | mr | 33 | 0 | 1 | 1 | 0 | 2 | 0 | 0 | 0 | 10.4 | 6.2 | 16.6 | 9.9 | 1.9 | 1.6 | 1.84 |
| Joe Saunders* | Cle | sp | 24 | 3 | 3 | 1 | 0 | 2 | 0 | 0 | 1 | 9.7 | 5.3 | 15.0 | 3.3 | 2.2 | 0.6 | 1.67 |
| Scott Schoeneweis* | Bal | mr | 31 | 4 | 1 | 2 | 2 | 1 | 0 | 0 | 0 | 8.3 | 3.7 | 12.4 | 6.8 | 0.0 | 1.8 | 1.34 |
| Rudy Seanez | Tex | mr | 36 | 1 | 5 | 0 | 1 | 3 | 0 | 0 | 2 | 8.2 | 3.4 | 11.7 | 13.6 | 0.7 | 4.0 | 1.28 |
| Bobby Seay* | LAA | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 27.0 | 6.8 | 33.8 | 13.5 | 0.0 | 2.0 | 3.75 |
| Aaron Sele | Sea | sp | 35 | 5 | 2 | 0 | 4 | 0 | 0 | 3 | 3 | 13.0 | 2.6 | 15.9 | 3.9 | 1.6 | 1.5 | 1.73 |
| Ben Sheets | Oak | sp | 26 | 17 | 7 | 1 | 4 | 6 | 0 | 1 | 7 | 9.4 | 2.1 | 11.7 | 7.0 | 1.0 | 3.4 | 1.28 |
| George Sherrill* | KCR | mr | 28 | 2 | 1 | 4 | 4 | 2 | 0 | 1 | 1 | 7.2 | 4.2 | 12.6 | 12.9 | 0.9 | 3.1 | 1.27 |
| Brian Shouse* | Tor | mr | 36 | 1 | 2 | 4 | 0 | 1 | 0 | 2 | 2 | 9.3 | 4.3 | 13.6 | 4.6 | 1.1 | 1.1 | 1.51 |
| Rafael Soriano | Min | mr | 25 | 2 | 0 | 3 | 3 | 2 | 0 | 0 | 0 | 10.7 | 5.6 | 18.0 | 7.9 | 1.1 | 1.4 | 1.81 |
| Justin Speier | Sea | mr | 31 | 2 | 0 | 0 | 8 | 0 | 3 | 1 | 4 | 6.8 | 1.5 | 9.0 | 7.3 | 0.9 | 5.0 | 0.92 |
| Ryan Speier | Tor | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.0 | 1.3 | 5.4 | 0.0 | 0.0 | 0.0 | 0.60 |
| Mike Stanton* | Mtl | mr | 38 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0.0 | 0.0 | 13.5 | 0.0 | 99.0 | 0.00 |
| Huston Street | NYY | cl | 21 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 3 | 5.2 | 3.1 | 8.4 | 7.9 | 0.8 | 2.5 | 0.92 |
| Tanyon Sturtze | Tex | mr | 34 | 3 | 0 | 0 | 5 | 2 | 0 | 0 | 1 | 9.2 | 3.0 | 13.5 | 2.7 | 1.3 | 0.9 | 1.35 |
| Jeff Suppan | Was | sp | 30 | 11 | 4 | 3 | 6 | 13 | 1 | 4 | 7 | 8.8 | 3.1 | 12.1 | 4.7 | 0.6 | 1.5 | 1.32 |
| Jack Taschner* | NYY | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.9 | 3.9 | 7.7 | 11.6 | 0.0 | 3.0 | 0.86 |
| Brett Tomko | NYY | sp | 32 | 15 | 6 | 4 | 7 | 3 | 0 | 4 | 8 | 10.1 | 2.4 | 12.9 | 5.8 | 1.4 | 2.4 | 1.40 |
| Salomon Torres | Det | mr | 33 | 1 | 3 | 0 | 4 | 6 | 0 | 0 | 2 | 6.1 | 3.3 | 9.9 | 6.1 | 0.5 | 1.9 | 1.05 |
| Josh Towers | Tex | sp | 28 | 9 | 3 | 0 | 6 | 1 | 2 | 7 | 4 | 9.4 | 1.1 | 10.8 | 5.2 | 0.7 | 4.6 | 1.17 |
| Ugueth Urbina | KCR | mr | 31 | 4 | 5 | 1 | 2 | 1 | 0 | 2 | 4 | 5.5 | 4.1 | 9.8 | 11.0 | 1.3 | 2.7 | 1.06 |
| Ismael Valdez | Cle | sp | 31 | 4 | 1 | 2 | 3 | 1 | 0 | 0 | 2 | 15.3 | 2.5 | 18.6 | 3.3 | 1.4 | 1.3 | 1.98 |
| Jose Valverde | Mtl | mr | 25 | 2 | 0 | 2 | 0 | 5 | 0 | 2 | 2 | 7.4 | 3.7 | 11.0 | 9.4 | 1.1 | 2.5 | 1.23 |
| Claudio Vargas | Cle | sp | 27 | 9 | 0 | 1 | 7 | 5 | 0 | 4 | 0 | 9.3 | 2.6 | 12.3 | 5.2 | 1.1 | 2.0 | 1.32 |
| Justin Verlander | Cle | sp | 22 | 3 | 3 | 0 | 0 | 2 | 0 | 0 | 2 | 13.2 | 2.2 | 15.4 | 3.3 | 1.4 | 1.5 | 1.71 |
| Luis Vizcaino | NYY | mr | 30 | 3 | 1 | 1 | 2 | 3 | 0 | 0 | 4 | 11.4 | 3.3 | 15.0 | 4.9 | 0.9 | 1.5 | 1.63 |
| Ryan Vogelsong | Was | mr | 27 | 5 | 1 | 0 | 10 | 2 | 0 | 2 | 8 | 8.3 | 4.7 | 14.0 | 4.6 | 0.4 | 1.0 | 1.44 |
| Edison Volquez | Cle | sp | 21 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 1 | 19.3 | 3.2 | 24.4 | 4.5 | 0.6 | 1.4 | 2.50 |
| Ryan Wagner | Bos | mr | 22 | 2 | 1 | 1 | 3 | 3 | 1 | 1 | 0 | 11.0 | 2.8 | 14.2 | 6.5 | 0.6 | 2.3 | 1.54 |
| Tim Wakefield | Tex | sp | 38 | 9 | 2 | 0 | 12 | 2 | 0 | 0 | 4 | 9.0 | 3.1 | 12.6 | 6.2 | 1.9 | 2.0 | 1.34 |
| Jamie Walker* | Mtl | mr | 33 | 2 | 4 | 0 | 3 | 0 | 0 | 1 | 1 | 12.0 | 4.3 | 17.1 | 4.3 | 1.3 | 1.0 | 1.81 |
| John Wasdin | Bal | mr | 32 | 1 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 7.9 | 2.6 | 10.5 | 3.9 | 1.0 | 1.5 | 1.17 |
| Jarrod Washburn* | Det | sp | 30 | 3 | 0 | 3 | 11 | 0 | 0 | 10 | 6 | 9.4 | 2.5 | 12.4 | 5.1 | 1.1 | 2.1 | 1.32 |
| Jeff Weaver | Sea | sp | 28 | 13 | 6 | 5 | 20 | 0 | 0 | 4 | 4 | 9.6 | 2.0 | 12.4 | 5.2 | 1.3 | 2.6 | 1.28 |
| Brandon Webb | Det | sp | 26 | 26 | 8 | 10 | 0 | 8 | 1 | 2 | 3 | 8.5 | 2.2 | 10.8 | 5.2 | 0.7 | 2.3 | 1.20 |
| David Wells* | Bal | sp | 42 | 14 | 2 | 0 | 9 | 6 | 1 | 3 | 9 | 12.1 | 1.5 | 14.1 | 5.4 | 1.0 | 3.6 | 1.51 |
| Jake Westbrook | Tex | sp | 27 | 4 | 5 | 0 | 7 | 0 | 0 | 5 | 5 | 10.3 | 2.2 | 12.7 | 5.3 | 0.8 | 2.5 | 1.38 |
| Dan Wheeler |   | mr | 27 | 3 | 3 | 0 | 1 | 0 | 0 | 1 | 1 | 6.6 | 1.6 | 8.3 | 7.3 | 0.7 | 4.6 | 0.91 |
| Rick White | Cle | mr | 36 | 5 | 2 | 2 | 6 | 5 | 0 | 4 | 1 | 11.0 | 3.0 | 14.7 | 4.6 | 0.5 | 1.5 | 1.55 |
| Dave Williams* | KCR | sp | 26 | 11 | 10 | 1 | 11 | 4 | 0 | 2 | 0 | 8.8 | 2.6 | 12.0 | 4.8 | 1.1 | 1.8 | 1.27 |
| Jerome Williams |   | sp | 23 | 8 | 3 | 2 | 9 | 2 | 0 | 2 | 4 | 9.2 | 3.1 | 12.9 | 4.6 | 0.9 | 1.5 | 1.37 |
| Woody Williams | ChW | sp | 38 | 13 | 6 | 1 | 2 | 2 | 0 | 2 | 10 | 9.6 | 2.8 | 12.5 | 5.6 | 1.8 | 2.0 | 1.38 |
| Scott Williamson | Min | mr | 29 | 2 | 0 | 0 | 3 | 3 | 0 | 0 | 1 | 10.3 | 3.0 | 14.3 | 10.3 | 2.3 | 3.4 | 1.48 |
| Dontrelle Willis* | Was | sp | 23 | 3 | 2 | 7 | 5 | 4 | 0 | 3 | 8 | 8.0 | 2.3 | 10.4 | 6.2 | 0.6 | 2.7 | 1.14 |
| C.J. Wilson* | Min | mr | 24 | 4 | 1 | 5 | 4 | 10 | 1 | 3 | 1 | 11.7 | 3.7 | 15.9 | 5.9 | 1.3 | 1.6 | 1.71 |
| Paul Wilson | Det | sp | 32 | 1 | 2 | 0 | 2 | 2 | 0 | 0 | 2 | 11.2 | 5.3 | 17.8 | 4.0 | 1.3 | 0.8 | 1.83 |
| Matt Wise | ChW | mr | 29 | 1 | 0 | 0 | 2 | 1 | 1 | 2 | 2 | 6.2 | 2.5 | 9.1 | 8.8 | 1.2 | 3.5 | 0.97 |
| Kerry Wood | Mtl | mr | 28 | 1 | 3 | 3 | 2 | 1 | 0 | 0 | 1 | 6.6 | 2.8 | 9.6 | 8.6 | 2.7 | 3.1 | 1.04 |
| Tim Worrell | ChW | mr | 37 | 0 | 1 | 2 | 1 | 1 | 1 | 0 | 0 | 9.2 | 2.7 | 12.3 | 6.5 | 0.0 | 2.4 | 1.33 |
| Jamey Wright | NYY | sp | 30 | 10 | 4 | 10 | 11 | 2 | 2 | 3 | 3 | 9.9 | 5.0 | 15.7 | 4.5 | 1.4 | 0.9 | 1.66 |
| Keiichi Yabu | Cle | mr | 36 | 4 | 4 | 2 | 9 | 6 | 0 | 1 | 4 | 8.7 | 2.7 | 12.3 | 5.8 | 0.3 | 2.1 | 1.27 |
| Esteban Yan | ChW | mr | 30 | 0 | 2 | 0 | 0 | 1 | 0 | 0 | 2 | 11.7 | 3.1 | 14.8 | 6.1 | 2.0 | 2.0 | 1.64 |
| Victor Zambrano | Det | sp | 29 | 20 | 2 | 2 | 12 | 4 | 2 | 3 | 2 | 9.4 | 3.5 | 13.7 | 5.3 | 0.7 | 1.5 | 1.43 |
| Barry Zito* | ChW | sp | 27 | 10 | 5 | 3 | 14 | 6 | 0 | 1 | 5 | 6.9 | 3.3 | 10.7 | 7.2 | 1.0 | 2.2 | 1.13 |
| Analytical |
| Name | Team | P | Age | OPS | BIP | BABIP | TBW | TBW/BF | TBWH | TBWH/BF | RC | RC27 | RCERA | CERA |
| Jeremy Accardo | ChW | mr | 23 | .921 | 30 | .267 | 23 | .575 | 23 | .575 | 7.8 | 8.1 | 7.60 | 7.49 |
| Jose Acevedo | ChW | mr | 27 | .896 | 103 | .233 | 80 | .584 | 83 | .606 | 23.5 | 6.7 | 6.01 | 5.65 |
| Jeremy Affeldt* | Bos | mr | 26 | .707 | 237 | .321 | 145 | .424 | 147 | .430 | 38.5 | 4.4 | 3.96 | 4.10 |
| Wilson Alvarez* | Det | mr | 35 | .833 | 14 | .429 | 9 | .450 | 9 | .450 | 3.2 | 7.2 | 6.51 | 6.48 |
| Brian Anderson* | KCR | sp | 33 | .981 | 28 | .393 | 26 | .619 | 26 | .619 | 9.3 | 9.7 | 8.73 | 8.97 |
| Matt Anderson | Min | mr | 28 | 1.078 | 45 | .356 | 44 | .638 | 46 | .667 | 17.7 | 13.7 | 11.95 | 13.10 |
| Greg Aquino | Bal | mr | 27 | .864 | 143 | .329 | 126 | .529 | 131 | .550 | 40.7 | 7.2 | 6.38 | 6.20 |
| Ezequiel Astacio | Min | sp | 25 | .874 | 516 | .298 | 414 | .568 | 415 | .569 | 120.2 | 6.4 | 5.77 | 5.43 |
| Luis Ayala | Was | mr | 27 | .763 | 177 | .328 | 101 | .417 | 111 | .459 | 30.3 | 4.9 | 4.44 | 4.83 |
| Manny Aybar | Bos | mr | 33 | .975 | 164 | .354 | 157 | .633 | 157 | .633 | 51.2 | 8.7 | 7.88 | 6.66 |
| Danys Baez | Sea | cl | 27 | .710 | 291 | .271 | 168 | .422 | 174 | .437 | 42.9 | 4.0 | 3.61 | 3.68 |
| James Baldwin | Oak | mr | 33 | .756 | 131 | .267 | 75 | .469 | 76 | .475 | 19.4 | 4.6 | 4.14 | 4.25 |
| Cliff Bartosh* | Bos | mr | 25 | .954 | 122 | .230 | 132 | .641 | 134 | .650 | 38.3 | 7.5 | 6.79 | 6.72 |
| Jonah Bayliss | Bos | mr | 24 | .541 | 56 | .143 | 30 | .353 | 32 | .376 | 6.2 | 2.7 | 2.47 | 2.23 |
| Josh Beckett | KCR | sp | 25 | .643 | 571 | .289 | 338 | .389 | 349 | .401 | 81.0 | 3.5 | 3.09 | 2.89 |
| Armando Benitez | ChW | cl | 32 | .601 | 69 | .188 | 38 | .400 | 38 | .400 | 6.9 | 2.5 | 2.14 | 2.04 |
| Joaquin Benoit | Tor | mr | 27 | .555 | 181 | .260 | 97 | .344 | 97 | .344 | 20.8 | 2.7 | 2.35 | 2.22 |
| Kris Benson | ChW | sp | 30 | .775 | 605 | .266 | 383 | .486 | 385 | .489 | 101.9 | 4.9 | 4.48 | 4.59 |
| Jason Bergmann | KCR | mr | 23 | .488 | 61 | .197 | 31 | .323 | 31 | .323 | 5.7 | 2.1 | 1.86 | 1.54 |
| Rafael Betancourt | Oak | mr | 30 | .563 | 204 | .289 | 98 | .323 | 101 | .333 | 23.1 | 2.8 | 2.50 | 2.05 |
| Jeremy Bonderman | Oak | sp | 22 | .788 | 591 | .294 | 410 | .495 | 416 | .502 | 112.7 | 5.3 | 4.83 | 4.59 |
| Joe Borowski | Mtl | mr | 34 | .764 | 166 | .289 | 97 | .473 | 98 | .478 | 27.6 | 5.2 | 4.65 | 4.16 |
| Ricky Bottalico | Bos | mr | 35 | .727 | 217 | .318 | 124 | .409 | 131 | .432 | 34.5 | 4.5 | 4.03 | 4.82 |
| Blaine Boyer | Det | mr | 23 | .593 | 89 | .236 | 51 | .370 | 53 | .384 | 10.9 | 2.9 | 2.67 | 2.76 |
| Chad Bradford | Oak | mr | 30 | .829 | 97 | .361 | 53 | .457 | 55 | .474 | 18.1 | 6.5 | 6.04 | 6.82 |
| Craig Breslow* | Bal | mr | 24 | .792 | 11 | .273 | 7 | .500 | 7 | .500 | 1.4 | 3.7 | 3.69 | 5.91 |
| Doug Brocail | Tor | mr | 38 | .727 | 337 | .323 | 216 | .434 | 221 | .444 | 61.3 | 5.0 | 4.50 | 4.38 |
| Jim Brower | Cle | mr | 32 | .884 | 168 | .357 | 120 | .500 | 127 | .529 | 39.8 | 7.1 | 6.31 | 7.40 |
| Kevin Brown | Mtl | sp | 40 | .979 | 13 | .231 | 14 | .609 | 15 | .652 | 4.6 | 8.3 | 7.49 | 7.05 |
| Brian Bruney | NYY | cl | 23 | .924 | 66 | .409 | 61 | .540 | 64 | .566 | 19.9 | 8.0 | 7.23 | 9.01 |
| Ryan Bukvich | Min | mr | 27 | 1.057 | 23 | .391 | 31 | .633 | 33 | .673 | 11.3 | 11.8 | 10.19 | 12.89 |
| Bryan Bullington | LAA | mr | 24 | 1.025 | 17 | .235 | 14 | .583 | 16 | .667 | 5.4 | 9.7 | 9.31 | 9.04 |
| Nate Bump | Det | mr | 28 | 1.071 | 35 | .486 | 30 | .600 | 31 | .620 | 12.2 | 12.2 | 10.25 | 11.50 |
| Paul Byrd | Tor | sp | 34 | .734 | 726 | .281 | 407 | .451 | 413 | .457 | 111.2 | 4.6 | 4.17 | 3.62 |
| Tim Byrdak* | Sea | mr | 31 | .642 | 56 | .339 | 43 | .398 | 44 | .407 | 9.6 | 3.6 | 3.20 | 4.10 |
| Daniel Cabrera | Cle | sp | 24 | .638 | 500 | .290 | 321 | .390 | 333 | .405 | 80.8 | 3.8 | 3.45 | 3.35 |
| Matt Cain | NYY | sp | 20 | .506 | 87 | .195 | 39 | .315 | 40 | .323 | 6.8 | 1.9 | 1.73 | 1.86 |
| Kiko Calero | Bal | mr | 30 | .634 | 195 | .287 | 117 | .387 | 118 | .391 | 29.8 | 3.7 | 3.39 | 3.20 |
| Shawn Camp | KCR | mr | 29 | .912 | 15 | .200 | 12 | .571 | 13 | .619 | 3.8 | 7.4 | 7.18 | 7.46 |
| Matt Capps | Sea | mr | 21 | 1.700 | 7 | .571 | 9 | .900 | 10 | 1.000 | 5.4 | 36.6 | 32.95 | 42.66 |
| Chris Capuano* | NYY | sp | 26 | .763 | 750 | .284 | 503 | .472 | 513 | .482 | 138.8 | 5.2 | 4.70 | 4.56 |
| Chris Carpenter | Tex | sp | 30 | .663 | 705 | .287 | 428 | .412 | 431 | .415 | 101.8 | 3.6 | 3.24 | 3.02 |
| Hector Carrasco | LAA | mr | 35 | .659 | 286 | .238 | 174 | .406 | 181 | .422 | 40.9 | 3.5 | 3.15 | 3.08 |
| Lance Carter | Mtl | mr | 30 | .684 | 231 | .264 | 120 | .412 | 122 | .419 | 29.9 | 3.8 | 3.50 | 3.65 |
| Marcos Carvajal | KCR | mr | 20 | .735 | 209 | .268 | 147 | .473 | 149 | .479 | 36.1 | 4.4 | 4.01 | 3.83 |
| Frank Castillo | KCR | sp | 36 | .876 | 14 | .357 | 14 | .560 | 14 | .560 | 4.3 | 7.3 | 6.22 | 6.67 |
| Gustavo Chacin* | Bal | sp | 24 | .743 | 642 | .305 | 385 | .441 | 396 | .453 | 108.5 | 4.8 | 4.49 | 4.51 |
| Shawn Chacon | Det | sp | 27 | .677 | 532 | .242 | 276 | .407 | 287 | .423 | 68.3 | 3.8 | 3.38 | 3.37 |
| Bruce Chen* | Cle | sp | 28 | .709 | 615 | .260 | 376 | .443 | 383 | .451 | 92.7 | 4.1 | 3.74 | 3.76 |
| Jason Christiansen* | Mtl | mr | 35 | .111 | 18 | .056 | 1 | .053 | 1 | .053 | 0.1 | 0.1 | 0.11 | 0.07 |
| Vinnie Chulk | Tex | mr | 26 | .720 | 146 | .288 | 86 | .437 | 87 | .442 | 22.7 | 4.5 | 4.05 | 4.68 |
| Brandon Claussen* | LAA | sp | 26 | .758 | 631 | .301 | 387 | .452 | 399 | .466 | 113.2 | 5.1 | 4.66 | 4.46 |
| Jesus Colome | Cle | mr | 27 | .935 | 36 | .472 | 24 | .522 | 24 | .522 | 9.2 | 9.2 | 7.99 | 8.11 |
| Bartolo Colon | Sea | sp | 32 | .746 | 688 | .301 | 428 | .459 | 430 | .461 | 110.2 | 4.4 | 4.00 | 3.99 |
| Brian Cooper | Tor | mr | 30 | .473 | 9 | .222 | 3 | .273 | 3 | .273 | 0.4 | 1.2 | 1.11 | 1.73 |
| Francisco Cordero | Tex | cl | 30 | .701 | 141 | .355 | 106 | .422 | 108 | .430 | 28.9 | 4.6 | 4.18 | 4.36 |
| Doug Creek* | Was | mr | 36 | .820 | 37 | .297 | 26 | .510 | 26 | .510 | 7.8 | 6.0 | 5.57 | 4.69 |
| Juan Cruz | Min | mr | 26 | 1.000 | 268 | .414 | 288 | .603 | 304 | .636 | 105.0 | 10.0 | 9.01 | 9.08 |
| Jason Davis | KCR | mr | 25 | .657 | 78 | .308 | 39 | .379 | 40 | .388 | 10.3 | 3.8 | 3.44 | 3.57 |
| Zach Day | Bal | mr | 27 | .808 | 54 | .278 | 40 | .506 | 40 | .506 | 11.6 | 6.4 | 5.98 | 6.95 |
| Valerio de los Santos* | KCR | mr | 32 | .533 | 4 | .250 | 2 | .333 | 2 | .333 | 0.4 | 2.8 | 2.55 | 3.21 |
| Mike DeJean | Tor | mr | 34 | .759 | 262 | .294 | 171 | .455 | 179 | .476 | 47.8 | 5.0 | 4.52 | 4.58 |
| Manny Delcarmen | Cle | mr | 23 | .958 | 36 | .444 | 32 | .552 | 33 | .569 | 11.2 | 8.6 | 7.53 | 9.35 |
| Ryan Dempster | LAA | cl | 28 | .673 | 167 | .341 | 93 | .380 | 95 | .388 | 24.5 | 3.9 | 3.52 | 3.83 |
| Elmer Dessens | Sea | mr | 34 | .688 | 346 | .269 | 181 | .417 | 184 | .424 | 44.0 | 3.7 | 3.35 | 3.26 |
| Joey Devine | Bos | mr | 21 | .962 | 94 | .255 | 80 | .635 | 80 | .635 | 23.5 | 7.5 | 6.71 | 7.46 |
| R.A. Dickey | KCR | mr | 30 | .914 | 70 | .286 | 65 | .575 | 68 | .602 | 19.2 | 7.1 | 6.57 | 7.21 |
| Craig Dingman | Det | mr | 31 | .682 | 64 | .281 | 38 | .409 | 39 | .419 | 9.1 | 3.5 | 3.19 | 3.32 |
| Juan Dominguez | Min | mr | 25 | .813 | 365 | .304 | 238 | .497 | 242 | .505 | 70.6 | 5.8 | 5.34 | 5.14 |
| Octavio Dotel | Oak | cl | 31 | .741 | 72 | .236 | 55 | .470 | 57 | .487 | 13.9 | 4.6 | 4.18 | 3.97 |
| Scott Downs* | LAA | sp | 29 | .670 | 177 | .282 | 108 | .406 | 112 | .421 | 25.8 | 3.7 | 3.35 | 3.73 |
| Zach Duke* | Tor | sp | 22 | .604 | 335 | .284 | 170 | .357 | 175 | .368 | 38.3 | 2.9 | 2.63 | 2.57 |
| Adam Eaton | LAA | sp | 27 | .783 | 491 | .299 | 322 | .474 | 334 | .492 | 94.5 | 5.5 | 4.96 | 4.58 |
| Scott Erickson | KCR | mr | 37 | .564 | 38 | .184 | 15 | .349 | 15 | .349 | 3.1 | 2.5 | 2.35 | 2.26 |
| Kelvim Escobar | Min | mr | 29 | .707 | 213 | .258 | 154 | .462 | 156 | .468 | 35.6 | 3.9 | 3.56 | 2.73 |
| Mike Esposito | Bos | sp | 23 | .840 | 71 | .324 | 42 | .500 | 42 | .500 | 13.5 | 6.9 | 6.31 | 6.82 |
| Shawn Estes* | Tor | sp | 32 | .778 | 448 | .263 | 278 | .483 | 281 | .489 | 72.8 | 4.9 | 4.37 | 4.72 |
| Seth Etherton | ChW | sp | 28 | .624 | 150 | .180 | 84 | .416 | 85 | .421 | 17.7 | 3.2 | 3.03 | 2.75 |
| Dana Eveland* | Cle | mr | 21 | .715 | 128 | .344 | 75 | .421 | 75 | .421 | 20.1 | 4.5 | 4.14 | 4.69 |
| Scott Eyre* | Oak | mr | 33 | .628 | 217 | .230 | 127 | .390 | 132 | .405 | 29.5 | 3.3 | 3.07 | 2.86 |
| Kyle Farnsworth | Det | mr | 29 | .533 | 192 | .302 | 114 | .312 | 121 | .332 | 25.0 | 2.5 | 2.23 | 2.24 |
| Jeff Fassero* | Tex | mr | 42 | .745 | 246 | .301 | 148 | .446 | 151 | .455 | 41.5 | 4.9 | 4.46 | 4.36 |
| Ron Flores* | KCR | mr | 25 | .775 | 51 | .294 | 31 | .470 | 31 | .470 | 8.4 | 4.8 | 4.55 | 4.78 |
| Josh Fogg | Bal | sp | 28 | .834 | 313 | .294 | 204 | .511 | 208 | .521 | 57.6 | 5.6 | 5.03 | 5.25 |
| Keith Foulke | Oak | cl | 32 | 1.130 | 109 | .330 | 115 | .742 | 116 | .748 | 43.5 | 12.8 | 11.48 | 10.63 |
| Jeff Francis* | Bos | sp | 24 | .742 | 509 | .301 | 313 | .452 | 316 | .457 | 85.3 | 4.8 | 4.31 | 4.24 |
| Brian Fuentes* | Bal | cl | 29 | .400 | 148 | .189 | 59 | .231 | 67 | .263 | 9.8 | 1.3 | 1.20 | 1.14 |
| Jairo Garcia | Bos | mr | 22 | 1.212 | 18 | .444 | 16 | .667 | 16 | .667 | 7.1 | 17.4 | 15.65 | 14.30 |
| Jon Garland | Mtl | sp | 25 | .652 | 331 | .263 | 165 | .384 | 171 | .398 | 42.5 | 3.7 | 3.32 | 3.10 |
| Dave Gassner* | Sea | sp | 26 | .795 | 40 | .300 | 23 | .489 | 23 | .489 | 7.1 | 6.2 | 5.73 | 5.15 |
| Geoff Geary | LAA | mr | 28 | .769 | 283 | .318 | 176 | .461 | 180 | .471 | 50.1 | 5.3 | 4.74 | 5.05 |
| Matt Ginter | KCR | mr | 27 | 1.000 | 2 | .500 | 1 | .500 | 1 | .500 | 0.5 | 13.5 | 12.15 | 14.52 |
| Gary Glover | KCR | sp | 28 | .826 | 218 | .376 | 161 | .497 | 163 | .503 | 49.8 | 6.2 | 5.55 | 5.24 |
| Jimmy Gobble* | Cle | mr | 23 | .870 | 392 | .352 | 304 | .526 | 310 | .536 | 97.3 | 7.3 | 6.72 | 7.18 |
| Jeremi Gonzalez | Oak | mr | 30 | .819 | 200 | .330 | 128 | .478 | 134 | .500 | 40.7 | 6.1 | 5.59 | 5.32 |
| Tom Gordon | Bal | mr | 37 | .507 | 310 | .203 | 147 | .324 | 148 | .326 | 28.5 | 2.2 | 2.02 | 1.69 |
| John Grabow* | KCR | mr | 26 | .687 | 210 | .300 | 127 | .416 | 129 | .423 | 31.2 | 3.8 | 3.48 | 3.58 |
| Danny Graves | KCR | cl | 31 | 1.778 | 8 | .500 | 13 | 1.083 | 13 | 1.083 | 7.2 | 48.5 | 43.66 | 43.13 |
| Zack Greinke | Bos | sp | 21 | .919 | 508 | .352 | 362 | .544 | 372 | .559 | 126.4 | 8.2 | 7.35 | 7.10 |
| Buddy Groom* | Sea | mr | 39 | 1.000 | 9 | .444 | 5 | .556 | 5 | .556 | 1.7 | 7.5 | 6.75 | 8.38 |
| Kevin Gryboski | Bal | mr | 31 | .762 | 43 | .302 | 24 | .429 | 26 | .464 | 6.7 | 4.9 | 4.55 | 5.20 |
| Eddie Guardado* |   | cl | 34 | .610 | 219 | .247 | 118 | .375 | 121 | .384 | 26.5 | 3.0 | 2.73 | 2.28 |
| John Halama* | KCR | mr | 33 | .770 | 177 | .322 | 98 | .439 | 104 | .466 | 29.6 | 5.3 | 4.80 | 4.53 |
| Brad Halsey* | Mtl | sp | 24 | .747 | 323 | .266 | 195 | .459 | 200 | .471 | 51.4 | 4.6 | 4.15 | 4.04 |
| Mike Hampton* | Det | sp | 32 | .751 | 247 | .279 | 144 | .462 | 144 | .462 | 36.7 | 4.5 | 4.15 | 4.52 |
| Craig Hansen | Bos | mr | 21 | .991 | 48 | .313 | 39 | .639 | 39 | .639 | 11.8 | 7.8 | 7.36 | 8.12 |
| Aaron Harang | Was | sp | 27 | .618 | 592 | .257 | 312 | .380 | 320 | .389 | 72.4 | 3.2 | 2.91 | 2.52 |
| Chad Harville | Sea | mr | 28 | .758 | 144 | .285 | 104 | .471 | 107 | .484 | 26.0 | 4.6 | 4.13 | 4.89 |
| Shigetoshi Hasegawa | LAA | mr | 36 | .659 | 413 | .276 | 203 | .387 | 207 | .395 | 53.6 | 3.9 | 3.47 | 3.43 |
| LaTroy Hawkins | Cle | mr | 32 | .852 | 226 | .385 | 150 | .505 | 150 | .505 | 46.3 | 6.3 | 5.68 | 5.88 |
| Aaron Heilman | Oak | mr | 26 | .613 | 416 | .262 | 239 | .378 | 243 | .384 | 52.5 | 3.0 | 2.72 | 2.79 |
| Mark Hendrickson* | LAA | sp | 31 | .900 | 403 | .333 | 288 | .554 | 292 | .562 | 92.5 | 7.3 | 6.59 | 6.17 |
| Clay Hensley | Bal | mr | 25 | .354 | 23 | .043 | 10 | .278 | 10 | .278 | 0.8 | 0.7 | 0.61 | 0.75 |
| Dustin Hermanson | Bal | cl | 32 | .648 | 227 | .238 | 124 | .392 | 129 | .408 | 30.3 | 3.6 | 3.29 | 3.21 |
| Felix Hernandez | Min | sp | 19 | .544 | 283 | .269 | 149 | .331 | 152 | .338 | 31.9 | 2.6 | 2.32 | 2.18 |
| Livan Hernandez | Was | sp | 30 | .842 | 680 | .351 | 442 | .491 | 456 | .507 | 143.5 | 6.6 | 5.99 | 6.18 |
| Orlando Hernandez | Tor | sp | 35 | .782 | 414 | .295 | 288 | .464 | 307 | .494 | 83.9 | 5.3 | 4.86 | 4.76 |
| Roberto Hernandez | Tex | mr | 40 | .645 | 191 | .288 | 104 | .382 | 105 | .386 | 25.6 | 3.5 | 3.20 | 3.20 |
| Runelvys Hernandez | ChW | sp | 27 | .850 | 493 | .292 | 364 | .526 | 374 | .540 | 109.1 | 6.5 | 5.97 | 5.84 |
| Trevor Hoffman | Det | cl | 37 | .509 | 187 | .278 | 83 | .293 | 85 | .300 | 17.1 | 2.1 | 1.95 | 1.88 |
| D.J. Houlton | KCR | sp | 25 | 1.093 | 175 | .371 | 166 | .661 | 172 | .685 | 64.5 | 12.2 | 11.12 | 11.22 |
| J.P. Howell* |   | sp | 22 | .765 | 186 | .285 | 143 | .488 | 144 | .491 | 37.9 | 5.1 | 4.59 | 4.60 |
| Luke Hudson | Was | sp | 28 | .533 | 4 | .250 | 2 | .333 | 2 | .333 | 0.4 | 2.8 | 3.40 | 4.47 |
| Tim Hudson | Det | sp | 29 | .715 | 666 | .270 | 374 | .432 | 385 | .445 | 94.4 | 4.1 | 3.68 | 3.83 |
| Kazuhisa Ishii* | Oak | sp | 31 | .857 | 323 | .279 | 233 | .527 | 242 | .548 | 69.9 | 6.4 | 5.90 | 6.10 |
| Jason Isringhausen | Sea | cl | 32 | .584 | 202 | .238 | 103 | .356 | 105 | .363 | 20.5 | 2.4 | 2.25 | 2.19 |
| Edwin Jackson | Min | sp | 21 | .856 | 170 | .288 | 117 | .518 | 121 | .535 | 38.8 | 7.3 | 6.88 | 5.98 |
| Chuck James* | Bos | mr | 23 | .725 | 25 | .160 | 18 | .500 | 18 | .500 | 4.4 | 4.7 | 4.25 | 4.19 |
| Bobby Jenks | KCR | mr | 24 | .585 | 193 | .321 | 123 | .363 | 123 | .363 | 26.8 | 2.9 | 2.62 | 2.31 |
| Jason Johnson | Tex | sp | 31 | .752 | 554 | .287 | 316 | .458 | 318 | .461 | 83.0 | 4.5 | 4.16 | 4.27 |
| Tyler Johnson* | Sea | mr | 24 | .500 | 6 | .333 | 2 | .250 | 2 | .250 | 0.5 | 2.3 | 2.03 | 1.95 |
| Jorge Julio | Cle | mr | 26 | .825 | 113 | .389 | 85 | .483 | 86 | .489 | 27.4 | 6.4 | 5.68 | 5.82 |
| Scott Kazmir* | Bos | sp | 21 | .693 | 503 | .270 | 348 | .441 | 353 | .447 | 85.7 | 4.2 | 3.81 | 3.66 |
| Joe Kennedy* | Min | sp | 26 | .833 | 583 | .346 | 376 | .486 | 386 | .499 | 121.9 | 6.6 | 5.90 | 5.96 |
| Byung-Hyun Kim | LAA | sp | 26 | .745 | 62 | .290 | 39 | .448 | 41 | .471 | 11.0 | 5.1 | 4.55 | 4.06 |
| Steve Kline* | Cle | mr | 32 | .929 | 121 | .322 | 104 | .588 | 106 | .599 | 32.1 | 7.3 | 6.71 | 7.06 |
| Dae-Sung Koo* | Sea | mr | 35 | .639 | 74 | .270 | 40 | .381 | 40 | .381 | 9.6 | 3.3 | 3.14 | 2.75 |
| Mike Koplove | Tor | mr | 28 | .678 | 147 | .252 | 83 | .407 | 88 | .431 | 21.3 | 4.0 | 3.61 | 3.24 |
| Hong-Chih Kuo* | Bos | mr | 23 | .740 | 68 | .279 | 63 | .492 | 63 | .492 | 15.0 | 4.3 | 3.92 | 3.83 |
| John Lackey | Bal | sp | 26 | .710 | 540 | .346 | 339 | .415 | 349 | .428 | 93.8 | 4.5 | 4.09 | 4.20 |
| Brandon League | Min | mr | 22 | .961 | 133 | .323 | 115 | .596 | 117 | .606 | 37.1 | 8.5 | 7.51 | 8.58 |
| Brad Lidge | ChW | cl | 28 | .711 | 129 | .295 | 102 | .449 | 104 | .458 | 26.9 | 4.5 | 4.09 | 3.95 |
| Francisco Liriano* | Min | sp | 21 | .746 | 97 | .402 | 84 | .462 | 85 | .467 | 21.9 | 4.5 | 4.15 | 4.21 |
| Esteban Loaiza | LAA | sp | 33 | .771 | 646 | .358 | 395 | .449 | 401 | .456 | 121.3 | 5.5 | 4.93 | 4.90 |
| Kameron Loe | NYY | mr | 23 | .516 | 66 | .273 | 23 | .264 | 25 | .287 | 5.0 | 2.0 | 1.80 | 2.05 |
| Braden Looper | LAA | cl | 30 | .668 | 169 | .237 | 80 | .386 | 86 | .415 | 18.6 | 3.2 | 2.88 | 3.10 |
| Rodrigo Lopez | NYY | sp | 29 | .698 | 673 | .273 | 373 | .420 | 382 | .430 | 98.8 | 4.3 | 3.85 | 3.80 |
| Derek Lowe | Mtl | sp | 32 | .762 | 724 | .294 | 448 | .466 | 454 | .472 | 118.8 | 4.7 | 4.21 | 4.24 |
| Greg Maddux | Bal | sp | 39 | .724 | 465 | .320 | 233 | .411 | 240 | .423 | 63.7 | 4.2 | 3.81 | 3.96 |
| Ryan Madson | NYY | mr | 24 | .716 | 274 | .277 | 188 | .444 | 194 | .459 | 46.7 | 4.1 | 3.72 | 3.64 |
| Mike Maroth* | Tor | sp | 27 | .774 | 633 | .278 | 386 | .461 | 402 | .480 | 108.4 | 5.0 | 4.52 | 4.78 |
| Damaso Marte* | Det | mr | 30 | .788 | 125 | .360 | 100 | .476 | 103 | .490 | 28.4 | 5.6 | 5.00 | 5.43 |
| Darrell May* | ChW | mr | 33 | .863 | 173 | .277 | 131 | .557 | 132 | .562 | 36.5 | 6.0 | 5.44 | 4.99 |
| Dustin McGowan | Cle | sp | 23 | .707 | 205 | .278 | 126 | .416 | 137 | .452 | 34.1 | 4.5 | 4.08 | 4.21 |
| Brian Meadows | Mtl | mr | 29 | .753 | 133 | .338 | 73 | .445 | 73 | .445 | 20.2 | 4.6 | 4.15 | 3.81 |
| Kent Mercker* | Tex | mr | 37 | .831 | 67 | .313 | 44 | .512 | 45 | .523 | 11.6 | 5.1 | 4.78 | 4.68 |
| Wade Miller | Bos | sp | 28 | .804 | 283 | .304 | 215 | .505 | 218 | .512 | 63.5 | 6.1 | 5.53 | 5.44 |
| Brian Moehler | Det | sp | 33 | .745 | 194 | .309 | 103 | .436 | 105 | .445 | 30.7 | 5.0 | 4.57 | 4.29 |
| Matt Morris |   | sp | 30 | .702 | 699 | .265 | 386 | .429 | 395 | .439 | 96.4 | 3.9 | 3.59 | 3.53 |
| Mark Mulder* | Was | sp | 27 | .742 | 661 | .290 | 380 | .450 | 388 | .460 | 101.6 | 4.7 | 4.20 | 4.06 |
| Terry Mulholland* | LAA | mr | 42 | .600 | 38 | .211 | 18 | .383 | 18 | .383 | 3.9 | 3.0 | 2.75 | 1.89 |
| Scott Munter | NYY | mr | 25 | .776 | 213 | .300 | 128 | .467 | 130 | .474 | 34.5 | 5.1 | 4.64 | 5.21 |
| Mike Mussina | Oak | sp | 36 | .786 | 597 | .320 | 402 | .476 | 412 | .488 | 113.4 | 5.2 | 4.69 | 4.79 |
| Brett Myers | Oak | sp | 24 | .644 | 694 | .274 | 382 | .387 | 395 | .400 | 93.5 | 3.5 | 3.15 | 2.84 |
| Joe Nathan | Was | cl | 30 | .684 | 153 | .275 | 126 | .442 | 129 | .453 | 29.8 | 3.9 | 3.45 | 3.25 |
| Blaine Neal | ChW | mr | 27 | .885 | 44 | .318 | 29 | .558 | 29 | .558 | 9.1 | 6.8 | 5.97 | 5.72 |
| Hideo Nomo | Bos | sp | 36 | .858 | 314 | .328 | 221 | .518 | 224 | .525 | 72.5 | 7.6 | 6.86 | 7.03 |
| Ramon Ortiz | NYY | sp | 32 | .828 | 630 | .286 | 420 | .513 | 427 | .522 | 115.7 | 5.4 | 4.93 | 5.07 |
| Vicente Padilla | LAA | sp | 27 | .771 | 518 | .259 | 371 | .484 | 384 | .501 | 98.0 | 5.1 | 4.62 | 4.61 |
| Jonathan Papelbon | Min | mr | 24 | .800 | 91 | .385 | 66 | .455 | 69 | .476 | 21.3 | 6.3 | 5.62 | 5.72 |
| Chan Ho Park | Tor | sp | 32 | .830 | 336 | .363 | 233 | .485 | 240 | .500 | 71.4 | 6.3 | 5.60 | 5.85 |
| Jake Peavy | ChW | sp | 24 | .633 | 619 | .263 | 366 | .398 | 372 | .405 | 82.1 | 3.2 | 2.90 | 2.43 |
| Joel Peralta | Tex | mr | 29 | .830 | 70 | .314 | 56 | .523 | 57 | .533 | 16.1 | 6.0 | 5.21 | 4.97 |
| Odalis Perez* | Min | sp | 28 | .776 | 446 | .303 | 285 | .473 | 289 | .480 | 76.8 | 4.9 | 4.42 | 4.28 |
| Oliver Perez* | LAA | sp | 23 | .770 | 189 | .228 | 159 | .513 | 160 | .516 | 39.2 | 4.9 | 4.51 | 4.75 |
| Tommy Phelps* | Bos | mr | 31 | .824 | 147 | .272 | 92 | .479 | 102 | .531 | 28.5 | 6.1 | 5.33 | 5.11 |
| Joel Pineiro | Min | sp | 26 | .787 | 695 | .331 | 427 | .470 | 432 | .475 | 123.5 | 5.3 | 4.77 | 4.75 |
| Cliff Politte | ChW | mr | 31 | .523 | 135 | .178 | 62 | .326 | 65 | .342 | 11.8 | 2.1 | 1.88 | 1.56 |
| Mark Prior | KCR | sp | 24 | .621 | 532 | .273 | 320 | .385 | 326 | .392 | 74.1 | 3.3 | 2.97 | 2.74 |
| Scott Proctor | NYY | mr | 28 | .832 | 131 | .260 | 118 | .554 | 118 | .554 | 32.6 | 6.0 | 5.36 | 4.93 |
| Paul Quantrill | LAA | mr | 36 | .925 | 50 | .420 | 34 | .523 | 36 | .554 | 12.9 | 8.7 | 7.84 | 7.34 |
| Brad Radke | Mtl | sp | 32 | .785 | 716 | .293 | 455 | .483 | 465 | .493 | 131.7 | 5.4 | 4.84 | 4.38 |
| Horacio Ramirez* |   | sp | 25 | .823 | 723 | .297 | 468 | .504 | 472 | .509 | 127.3 | 5.3 | 4.83 | 5.46 |
| Chris Ray | Cle | mr | 23 | .514 | 126 | .246 | 60 | .319 | 60 | .319 | 12.5 | 2.4 | 2.13 | 1.62 |
| Steve Reed | Oak | mr | 40 | .775 | 45 | .267 | 24 | .471 | 24 | .471 | 6.9 | 5.3 | 5.26 | 4.84 |
| Chris Reitsma | Was | mr | 27 | .539 | 341 | .258 | 127 | .301 | 128 | .303 | 28.4 | 2.4 | 2.17 | 2.04 |
| Mike Remlinger* | Cle | mr | 39 | .760 | 151 | .298 | 102 | .470 | 103 | .475 | 26.9 | 4.7 | 4.29 | 4.16 |
| Chris Resop | Cle | mr | 22 | .772 | 30 | .400 | 19 | .452 | 19 | .452 | 5.7 | 5.3 | 4.91 | 5.07 |
| Anthony Reyes | KCR | mr | 23 | .562 | 41 | .171 | 22 | .373 | 22 | .373 | 3.9 | 2.3 | 2.08 | 1.91 |
| Dennys Reyes* | ChW | mr | 28 | .601 | 85 | .247 | 48 | .372 | 49 | .380 | 11.2 | 3.5 | 3.05 | 3.39 |
| Matt Riley* | Min | mr | 25 | 1.127 | 53 | .358 | 53 | .679 | 54 | .692 | 19.9 | 12.8 | 12.42 | 12.84 |
| Ricardo Rincon* | Mtl | mr | 35 | .810 | 105 | .267 | 78 | .517 | 78 | .517 | 20.3 | 5.3 | 4.80 | 5.82 |
| Mariano Rivera | Tor | cl | 35 | .426 | 232 | .216 | 82 | .241 | 88 | .259 | 14.9 | 1.5 | 1.34 | 1.19 |
| Fernando Rodney | Min | mr | 28 | .597 | 165 | .242 | 97 | .380 | 98 | .384 | 19.8 | 2.7 | 2.49 | 2.26 |
| Francisco Rodriguez | Tor | cl | 23 | .660 | 214 | .243 | 167 | .435 | 168 | .438 | 38.6 | 3.7 | 3.37 | 2.94 |
| Kenny Rogers* | Bal | sp | 40 | .709 | 656 | .302 | 339 | .412 | 345 | .419 | 92.1 | 4.4 | 3.95 | 4.23 |
| J.C. Romero* | Sea | mr | 29 | .703 | 144 | .243 | 97 | .435 | 103 | .462 | 25.5 | 4.7 | 4.15 | 4.10 |
| Kirk Rueter* | KCR | sp | 34 | .513 | 21 | .190 | 8 | .320 | 8 | .320 | 1.6 | 2.1 | 1.89 | 1.02 |
| Glendon Rusch* | NYY | mr | 30 | .949 | 114 | .412 | 96 | .565 | 98 | .576 | 33.5 | 8.5 | 7.28 | 7.15 |
| B.J. Ryan* | Was | cl | 29 | .501 | 208 | .226 | 116 | .314 | 122 | .330 | 22.7 | 2.2 | 1.96 | 1.65 |
| C.C. Sabathia* | KCR | sp | 24 | .605 | 630 | .276 | 329 | .359 | 338 | .369 | 76.5 | 3.1 | 2.75 | 2.72 |
| Duaner Sanchez | Mtl | mr | 25 | .670 | 145 | .290 | 94 | .418 | 95 | .422 | 23.0 | 3.9 | 3.52 | 3.43 |
| Johan Santana* | Sea | sp | 26 | .637 | 647 | .275 | 382 | .392 | 388 | .398 | 91.4 | 3.4 | 3.07 | 2.69 |
| Julio Santana | Sea | mr | 32 | 1.061 | 43 | .395 | 54 | .692 | 54 | .692 | 18.5 | 10.2 | 9.19 | 8.82 |
| Victor Santos | Sea | sp | 28 | .804 | 448 | .319 | 285 | .486 | 288 | .491 | 87.3 | 6.0 | 5.37 | 5.06 |
| Scott Sauerbeck* | ChW | mr | 33 | .889 | 49 | .367 | 49 | .563 | 49 | .563 | 13.5 | 6.4 | 5.75 | 7.27 |
| Joe Saunders* | Cle | sp | 24 | .912 | 102 | .265 | 83 | .589 | 83 | .589 | 22.6 | 6.4 | 5.66 | 6.77 |
| Scott Schoeneweis* | Bal | mr | 31 | .612 | 156 | .314 | 77 | .350 | 79 | .359 | 17.4 | 3.0 | 2.66 | 3.22 |
| Rudy Seanez | Tex | mr | 36 | .697 | 135 | .378 | 112 | .436 | 113 | .440 | 26.7 | 3.9 | 3.51 | 3.45 |
| Bobby Seay* | LAA | mr | 27 | 1.056 | 6 | .667 | 5 | .556 | 5 | .556 | 2.4 | 16.0 | 14.38 | 18.29 |
| Aaron Sele | Sea | sp | 35 | .902 | 344 | .331 | 233 | .543 | 237 | .552 | 78.6 | 7.7 | 7.05 | 6.91 |
| Ben Sheets | Oak | sp | 26 | .711 | 543 | .306 | 319 | .428 | 323 | .434 | 85.7 | 4.3 | 3.93 | 3.81 |
| George Sherrill* | KCR | mr | 28 | .686 | 65 | .323 | 53 | .411 | 57 | .442 | 13.5 | 4.1 | 3.65 | 3.54 |
| Brian Shouse* | Tor | mr | 36 | .741 | 162 | .284 | 98 | .450 | 98 | .450 | 24.8 | 4.4 | 3.99 | 4.67 |
| Rafael Soriano | Min | mr | 25 | .920 | 50 | .340 | 44 | .557 | 47 | .595 | 14.8 | 8.3 | 7.48 | 6.66 |
| Justin Speier | Sea | mr | 31 | .602 | 292 | .236 | 150 | .363 | 158 | .383 | 32.9 | 2.8 | 2.53 | 2.27 |
| Ryan Speier | Tor | mr | 25 | .364 | 22 | .136 | 5 | .217 | 5 | .217 | 0.8 | 1.2 | 1.01 | 0.69 |
| Mike Stanton* | Mtl | mr | 38 | .000 | 2 | .000 | 0 | .000 | 0 | .000 | 0.0 | 0.0 | 0.00 | 0.00 |
| Huston Street | NYY | cl | 21 | .522 | 173 | .197 | 89 | .336 | 90 | .340 | 15.6 | 2.0 | 1.82 | 1.76 |
| Tanyon Sturtze | Tex | mr | 34 | .819 | 117 | .248 | 74 | .500 | 79 | .534 | 22.0 | 5.9 | 5.34 | 4.84 |
| Jeff Suppan | Was | sp | 30 | .663 | 661 | .278 | 333 | .389 | 339 | .396 | 83.6 | 3.7 | 3.36 | 3.59 |
| Jack Taschner* | NYY | mr | 27 | .387 | 11 | .182 | 5 | .263 | 5 | .263 | 0.7 | 1.3 | 1.29 | 1.02 |
| Brett Tomko | NYY | sp | 32 | .820 | 676 | .300 | 464 | .510 | 471 | .518 | 134.0 | 5.7 | 5.18 | 4.79 |
| Salomon Torres | Det | mr | 33 | .541 | 218 | .211 | 101 | .333 | 105 | .347 | 19.9 | 2.3 | 2.18 | 2.15 |
| Josh Towers | Tex | sp | 28 | .678 | 752 | .289 | 373 | .399 | 379 | .406 | 97.1 | 3.8 | 3.50 | 3.19 |
| Ugueth Urbina | KCR | mr | 31 | .633 | 190 | .211 | 150 | .426 | 152 | .432 | 31.8 | 3.3 | 2.95 | 2.61 |
| Ismael Valdez | Cle | sp | 31 | .987 | 129 | .388 | 90 | .570 | 93 | .589 | 32.9 | 9.1 | 8.25 | 8.79 |
| Jose Valverde | Mtl | mr | 25 | .642 | 153 | .268 | 99 | .404 | 99 | .404 | 24.3 | 3.8 | 3.35 | 3.18 |
| Claudio Vargas | Cle | sp | 27 | .743 | 525 | .274 | 315 | .458 | 322 | .468 | 88.1 | 5.0 | 4.51 | 4.09 |
| Justin Verlander | Cle | sp | 22 | .938 | 125 | .344 | 87 | .580 | 87 | .580 | 29.6 | 8.2 | 7.33 | 6.67 |
| Luis Vizcaino | NYY | mr | 30 | .844 | 233 | .339 | 154 | .507 | 156 | .513 | 46.3 | 6.2 | 5.52 | 5.72 |
| Ryan Vogelsong | Was | mr | 27 | .701 | 272 | .279 | 150 | .400 | 160 | .427 | 40.0 | 4.2 | 3.74 | 4.30 |
| Edison Volquez | Cle | sp | 21 | 1.185 | 61 | .475 | 52 | .675 | 55 | .714 | 22.5 | 14.5 | 13.04 | 12.27 |
| Ryan Wagner | Bos | mr | 22 | .778 | 250 | .352 | 154 | .457 | 157 | .466 | 42.3 | 4.9 | 4.51 | 4.95 |
| Tim Wakefield | Tex | sp | 38 | .803 | 596 | .258 | 436 | .512 | 448 | .526 | 120.0 | 5.5 | 4.95 | 4.85 |
| Jamie Walker* | Mtl | mr | 33 | .838 | 130 | .323 | 84 | .488 | 87 | .506 | 25.9 | 6.2 | 5.94 | 6.97 |
| John Wasdin | Bal | mr | 32 | .675 | 109 | .239 | 58 | .420 | 58 | .420 | 13.9 | 3.7 | 3.28 | 3.11 |
| Jarrod Washburn* | Det | sp | 30 | .737 | 657 | .280 | 378 | .439 | 389 | .451 | 100.9 | 4.4 | 4.08 | 4.17 |
| Jeff Weaver | Sea | sp | 28 | .751 | 718 | .283 | 421 | .446 | 441 | .467 | 118.6 | 4.8 | 4.35 | 4.36 |
| Brandon Webb | Det | sp | 26 | .670 | 785 | .280 | 414 | .409 | 414 | .409 | 95.5 | 3.4 | 3.06 | 3.08 |
| David Wells* | Bal | sp | 42 | .815 | 630 | .351 | 374 | .470 | 383 | .482 | 114.2 | 5.6 | 5.18 | 5.39 |
| Jake Westbrook | Tex | sp | 27 | .743 | 747 | .312 | 421 | .440 | 428 | .447 | 115.2 | 4.6 | 4.22 | 4.24 |
| Dan Wheeler |   | mr | 27 | .552 | 232 | .241 | 109 | .336 | 110 | .340 | 20.5 | 2.1 | 1.95 | 1.92 |
| Rick White | Cle | mr | 36 | .785 | 245 | .327 | 140 | .447 | 146 | .466 | 42.1 | 5.4 | 4.94 | 5.03 |
| Dave Williams* | KCR | sp | 26 | .750 | 564 | .273 | 343 | .460 | 354 | .475 | 88.1 | 4.4 | 3.98 | 4.04 |
| Jerome Williams |   | sp | 23 | .747 | 431 | .281 | 254 | .449 | 263 | .465 | 66.8 | 4.5 | 4.11 | 4.26 |
| Woody Williams | ChW | sp | 38 | .822 | 578 | .279 | 413 | .523 | 415 | .526 | 116.8 | 5.7 | 5.12 | 4.90 |
| Scott Williamson | Min | mr | 29 | .839 | 72 | .333 | 62 | .508 | 65 | .533 | 19.4 | 6.5 | 5.82 | 6.31 |
| Dontrelle Willis* | Was | sp | 23 | .635 | 799 | .273 | 410 | .383 | 415 | .387 | 94.1 | 3.2 | 2.87 | 2.76 |
| C.J. Wilson* | Min | mr | 24 | .837 | 241 | .344 | 162 | .489 | 166 | .502 | 51.9 | 6.6 | 5.90 | 6.36 |
| Paul Wilson | Det | sp | 32 | .858 | 49 | .306 | 33 | .493 | 35 | .522 | 10.0 | 6.1 | 5.93 | 7.26 |
| Matt Wise | ChW | mr | 29 | .594 | 139 | .216 | 81 | .377 | 83 | .386 | 17.3 | 2.9 | 2.63 | 2.32 |
| Kerry Wood | Mtl | mr | 28 | .740 | 277 | .181 | 234 | .512 | 236 | .516 | 50.7 | 4.0 | 3.60 | 3.54 |
| Tim Worrell | ChW | mr | 37 | .622 | 84 | .321 | 39 | .348 | 40 | .357 | 10.3 | 3.6 | 3.15 | 3.18 |
| Jamey Wright | NYY | sp | 30 | .895 | 420 | .290 | 326 | .555 | 337 | .574 | 96.8 | 6.8 | 6.08 | 6.08 |
| Keiichi Yabu | Cle | mr | 36 | .669 | 283 | .300 | 143 | .376 | 152 | .400 | 37.5 | 3.7 | 3.35 | 3.48 |
| Esteban Yan | ChW | mr | 30 | .941 | 110 | .345 | 91 | .591 | 91 | .591 | 27.0 | 7.0 | 6.19 | 6.89 |
| Victor Zambrano | Det | sp | 29 | .729 | 470 | .294 | 272 | .429 | 284 | .448 | 78.4 | 4.9 | 4.44 | 4.40 |
| Barry Zito* | ChW | sp | 27 | .634 | 668 | .240 | 390 | .394 | 404 | .408 | 87.9 | 3.2 | 2.95 | 2.98 |
| Start |
| Name | Team | P | Age | GS | CG | CG% | SHO | QS | QS% | RS | RS/G | RL | RLS | RL% | NP/G | STR% |
| Jeremy Accardo | ChW | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 22.7 | .610 |
| Jose Acevedo | ChW | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 | 34.9 | .650 |
| Jeremy Affeldt* | Bos | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 2 | .125 | 24.3 | .591 |
| Wilson Alvarez* | Det | mr | 35 | 1 | 0 | .000 | 0 | 0 | .000 | 2 | 2.0 | 2 | 2 | 1.000 | 76.0 | .658 |
| Brian Anderson* | KCR | sp | 33 | 2 | 0 | .000 | 0 | 0 | .000 | 6 | 3.0 | 1 | 0 | .000 | 52.7 | .677 |
| Matt Anderson | Min | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 3 | .333 | 28.8 | .510 |
| Greg Aquino | Bal | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 8 | .400 | 29.6 | .594 |
| Ezequiel Astacio | Min | sp | 25 | 28 | 2 | .071 | 0 | 10 | .357 | 131 | 4.7 | 13 | 6 | .462 | 92.3 | .649 |
| Luis Ayala | Was | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 4 | .160 | 17.0 | .660 |
| Manny Aybar | Bos | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 3 | .429 | 30.4 | .657 |
| Danys Baez | Sea | cl | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 8 | .276 | 24.6 | .615 |
| James Baldwin | Oak | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 4 | .500 | 28.3 | .638 |
| Cliff Bartosh* | Bos | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 5 | .556 | 28.0 | .601 |
| Jonah Bayliss | Bos | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 21.9 | .595 |
| Josh Beckett | KCR | sp | 25 | 32 | 3 | .094 | 3 | 20 | .625 | 134 | 4.2 | 26 | 8 | .308 | 101.3 | .628 |
| Armando Benitez | ChW | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 0 | .000 | 20.7 | .584 |
| Joaquin Benoit | Tor | mr | 27 | 10 | 0 | .000 | 0 | 7 | .700 | 38 | 3.8 | 9 | 5 | .556 | 96.8 | .628 |
| Kris Benson | ChW | sp | 30 | 28 | 6 | .214 | 1 | 16 | .571 | 140 | 5.0 | 15 | 5 | .333 | 97.8 | .645 |
| Jason Bergmann | KCR | mr | 23 | 1 | 0 | .000 | 0 | 1 | 1.000 | 2 | 2.0 | 5 | 1 | .200 | 28.9 | .580 |
| Rafael Betancourt | Oak | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 | 19.8 | .652 |
| Jeremy Bonderman | Oak | sp | 22 | 32 | 3 | .094 | 0 | 13 | .406 | 142 | 4.4 | 18 | 2 | .111 | 94.9 | .623 |
| Joe Borowski | Mtl | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 8 | .667 | 16.1 | .656 |
| Ricky Bottalico | Bos | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 8 | .471 | 23.6 | .599 |
| Blaine Boyer | Det | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 6 | .667 | 24.4 | .616 |
| Chad Bradford | Oak | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 2 | .200 | 18.5 | .650 |
| Craig Breslow* | Bal | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 14.7 | .568 |
| Doug Brocail | Tor | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 19 | .594 | 30.7 | .602 |
| Jim Brower | Cle | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 2 | .118 | 26.1 | .601 |
| Kevin Brown | Mtl | sp | 40 | 1 | 0 | .000 | 0 | 0 | .000 | 5 | 5.0 | 0 | 0 | .000 | 86.0 | .628 |
| Brian Bruney | NYY | cl | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 | 33.8 | .558 |
| Ryan Bukvich | Min | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 5 | .833 | 30.4 | .516 |
| Bryan Bullington | LAA | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 35.0 | .571 |
| Nate Bump | Det | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 26.2 | .618 |
| Paul Byrd | Tor | sp | 34 | 32 | 5 | .156 | 0 | 16 | .500 | 172 | 5.4 | 22 | 8 | .364 | 93.5 | .693 |
| Tim Byrdak* | Sea | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 6 | .500 | 24.8 | .569 |
| Daniel Cabrera | Cle | sp | 24 | 33 | 2 | .061 | 2 | 15 | .455 | 112 | 3.4 | 26 | 12 | .462 | 99.9 | .591 |
| Matt Cain | NYY | sp | 20 | 4 | 3 | .750 | 2 | 3 | .750 | 8 | 2.0 | 2 | 1 | .500 | 108.8 | .630 |
| Kiko Calero | Bal | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 1 | .083 | 24.7 | .641 |
| Shawn Camp | KCR | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 18.7 | .679 |
| Matt Capps | Sea | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 40.0 | .575 |
| Chris Capuano* | NYY | sp | 26 | 39 | 4 | .103 | 1 | 18 | .462 | 174 | 4.5 | 35 | 9 | .257 | 103.7 | .605 |
| Chris Carpenter | Tex | sp | 30 | 38 | 7 | .184 | 2 | 23 | .605 | 205 | 5.4 | 17 | 9 | .529 | 99.8 | .652 |
| Hector Carrasco | LAA | mr | 35 | 2 | 0 | .000 | 0 | 2 | 1.000 | 18 | 9.0 | 12 | 3 | .250 | 25.3 | .624 |
| Lance Carter | Mtl | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 0 | .000 | 31.8 | .644 |
| Marcos Carvajal | KCR | mr | 20 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 5 | .278 | 35.8 | .615 |
| Frank Castillo | KCR | sp | 36 | 1 | 0 | .000 | 0 | 0 | .000 | 4 | 4.0 | 0 | 0 | .000 | 95.0 | .537 |
| Gustavo Chacin* | Bal | sp | 24 | 34 | 3 | .088 | 0 | 18 | .529 | 162 | 4.8 | 20 | 8 | .400 | 92.6 | .617 |
| Shawn Chacon | Det | sp | 27 | 25 | 2 | .080 | 2 | 14 | .560 | 109 | 4.4 | 20 | 5 | .250 | 96.6 | .604 |
| Bruce Chen* | Cle | sp | 28 | 31 | 4 | .129 | 1 | 18 | .581 | 121 | 3.9 | 26 | 14 | .538 | 92.7 | .613 |
| Jason Christiansen* | Mtl | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 15.3 | .689 |
| Vinnie Chulk | Tex | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 5 | .556 | 23.6 | .613 |
| Brandon Claussen* | LAA | sp | 26 | 34 | 3 | .088 | 1 | 16 | .471 | 159 | 4.7 | 23 | 9 | .391 | 94.5 | .628 |
| Jesus Colome | Cle | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 21.9 | .629 |
| Bartolo Colon | Sea | sp | 32 | 34 | 3 | .088 | 1 | 17 | .500 | 139 | 4.1 | 24 | 14 | .583 | 100.3 | .644 |
| Brian Cooper | Tor | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 19.0 | .553 |
| Francisco Cordero | Tex | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 20.5 | .605 |
| Doug Creek* | Was | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 21.3 | .600 |
| Juan Cruz | Min | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 48 | 12 | .250 | 29.7 | .589 |
| Jason Davis | KCR | mr | 25 | 4 | 0 | .000 | 0 | 2 | .500 | 14 | 3.5 | 3 | 3 | 1.000 | 60.3 | .630 |
| Zach Day | Bal | mr | 27 | 2 | 0 | .000 | 0 | 0 | .000 | 9 | 4.5 | 4 | 3 | .750 | 32.9 | .557 |
| Valerio de los Santos* | KCR | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 7.7 | .522 |
| Mike DeJean | Tor | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 12 | .375 | 23.2 | .618 |
| Manny Delcarmen | Cle | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 21.5 | .586 |
| Ryan Dempster | LAA | cl | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 | 21.2 | .602 |
| Elmer Dessens | Sea | mr | 34 | 16 | 1 | .063 | 1 | 12 | .750 | 65 | 4.1 | 7 | 2 | .286 | 91.6 | .663 |
| Joey Devine | Bos | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 | 29.6 | .597 |
| R.A. Dickey | KCR | mr | 30 | 4 | 0 | .000 | 0 | 0 | .000 | 16 | 4.0 | 4 | 0 | .000 | 77.8 | .559 |
| Craig Dingman | Det | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 0 | .000 | 23.4 | .682 |
| Juan Dominguez | Min | mr | 25 | 17 | 3 | .176 | 0 | 9 | .529 | 62 | 3.6 | 16 | 7 | .438 | 101.2 | .645 |
| Octavio Dotel | Oak | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 0 | .000 | 23.4 | .590 |
| Scott Downs* | LAA | sp | 29 | 1 | 0 | .000 | 0 | 0 | .000 | 3 | 3.0 | 14 | 6 | .429 | 26.4 | .604 |
| Zach Duke* | Tor | sp | 22 | 18 | 4 | .222 | 0 | 12 | .667 | 87 | 4.8 | 18 | 5 | .278 | 93.2 | .635 |
| Adam Eaton | LAA | sp | 27 | 25 | 1 | .040 | 0 | 13 | .520 | 96 | 3.8 | 22 | 8 | .364 | 98.7 | .631 |
| Scott Erickson | KCR | mr | 37 | 2 | 0 | .000 | 0 | 1 | .500 | 10 | 5.0 | 1 | 0 | .000 | 71.5 | .552 |
| Kelvim Escobar | Min | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 3 | .300 | 35.7 | .623 |
| Mike Esposito | Bos | sp | 23 | 4 | 0 | .000 | 0 | 1 | .250 | 12 | 3.0 | 3 | 1 | .333 | 71.8 | .599 |
| Shawn Estes* | Tor | sp | 32 | 23 | 0 | .000 | 0 | 13 | .565 | 111 | 4.8 | 16 | 7 | .438 | 92.6 | .612 |
| Seth Etherton | ChW | sp | 28 | 7 | 2 | .286 | 0 | 4 | .571 | 28 | 4.0 | 3 | 0 | .000 | 104.4 | .599 |
| Dana Eveland* | Cle | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 7 | .438 | 27.6 | .588 |
| Scott Eyre* | Oak | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 8 | .296 | 18.9 | .619 |
| Kyle Farnsworth | Det | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 1 | .063 | 23.7 | .615 |
| Jeff Fassero* | Tex | mr | 42 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 11 | .407 | 26.2 | .605 |
| Ron Flores* | KCR | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 18.1 | .659 |
| Josh Fogg | Bal | sp | 28 | 13 | 1 | .077 | 0 | 4 | .308 | 75 | 5.8 | 14 | 2 | .143 | 56.9 | .643 |
| Keith Foulke | Oak | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 4 | .400 | 23.7 | .614 |
| Jeff Francis* | Bos | sp | 24 | 26 | 0 | .000 | 0 | 14 | .538 | 81 | 3.1 | 17 | 6 | .353 | 98.7 | .600 |
| Brian Fuentes* | Bal | cl | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 20.3 | .633 |
| Jairo Garcia | Bos | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 49.0 | .510 |
| Jon Garland | Mtl | sp | 25 | 16 | 2 | .125 | 1 | 10 | .625 | 112 | 7.0 | 16 | 9 | .563 | 97.1 | .643 |
| Dave Gassner* | Sea | sp | 26 | 2 | 0 | .000 | 0 | 0 | .000 | 6 | 3.0 | 2 | 0 | .000 | 50.0 | .647 |
| Geoff Geary | LAA | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 3 | .214 | 35.2 | .606 |
| Matt Ginter | KCR | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 2.5 | .600 |
| Gary Glover | KCR | sp | 28 | 12 | 0 | .000 | 0 | 4 | .333 | 47 | 3.9 | 16 | 2 | .125 | 65.2 | .647 |
| Jimmy Gobble* | Cle | mr | 23 | 24 | 0 | .000 | 0 | 6 | .250 | 76 | 3.2 | 41 | 17 | .415 | 65.1 | .582 |
| Jeremi Gonzalez | Oak | mr | 30 | 7 | 0 | .000 | 0 | 0 | .000 | 30 | 4.3 | 6 | 3 | .500 | 58.7 | .633 |
| Tom Gordon | Bal | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 6 | .286 | 22.5 | .621 |
| John Grabow* | KCR | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 7 | .368 | 23.1 | .607 |
| Danny Graves | KCR | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 13.5 | .500 |
| Zack Greinke | Bos | sp | 21 | 26 | 0 | .000 | 0 | 9 | .346 | 109 | 4.2 | 18 | 9 | .500 | 89.4 | .629 |
| Buddy Groom* | Sea | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 1 | .125 | 4.3 | .667 |
| Kevin Gryboski | Bal | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 27.6 | .575 |
| Eddie Guardado* |   | cl | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 6 | .286 | 21.6 | .677 |
| John Halama* | KCR | mr | 33 | 2 | 0 | .000 | 0 | 1 | .500 | 9 | 4.5 | 11 | 4 | .364 | 39.9 | .644 |
| Brad Halsey* | Mtl | sp | 24 | 16 | 1 | .063 | 0 | 10 | .625 | 108 | 6.8 | 6 | 3 | .500 | 93.0 | .647 |
| Mike Hampton* | Det | sp | 32 | 12 | 1 | .083 | 0 | 6 | .500 | 66 | 5.5 | 12 | 6 | .500 | 93.3 | .604 |
| Craig Hansen | Bos | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 28.6 | .607 |
| Aaron Harang | Was | sp | 27 | 29 | 3 | .103 | 3 | 20 | .690 | 114 | 3.9 | 8 | 4 | .500 | 107.5 | .654 |
| Chad Harville | Sea | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 8 | .320 | 24.8 | .585 |
| Shigetoshi Hasegawa | LAA | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 6 | .375 | 30.9 | .641 |
| LaTroy Hawkins | Cle | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 9 | .563 | 19.0 | .627 |
| Aaron Heilman | Oak | mr | 26 | 11 | 1 | .091 | 1 | 8 | .727 | 40 | 3.6 | 25 | 10 | .400 | 44.9 | .635 |
| Mark Hendrickson* | LAA | sp | 31 | 20 | 0 | .000 | 0 | 8 | .400 | 91 | 4.6 | 17 | 7 | .412 | 93.3 | .629 |
| Clay Hensley | Bal | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 30.6 | .556 |
| Dustin Hermanson | Bal | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 4 | .364 | 19.9 | .632 |
| Felix Hernandez | Min | sp | 19 | 16 | 1 | .063 | 1 | 13 | .813 | 76 | 4.8 | 3 | 0 | .000 | 107.9 | .629 |
| Livan Hernandez | Was | sp | 30 | 33 | 2 | .061 | 0 | 13 | .394 | 137 | 4.2 | 40 | 23 | .575 | 99.5 | .631 |
| Orlando Hernandez | Tor | sp | 35 | 25 | 2 | .080 | 0 | 12 | .480 | 145 | 5.8 | 21 | 7 | .333 | 92.4 | .605 |
| Roberto Hernandez | Tex | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 9 | .692 | 24.2 | .608 |
| Runelvys Hernandez | ChW | sp | 27 | 29 | 0 | .000 | 0 | 6 | .207 | 149 | 5.1 | 27 | 13 | .481 | 90.4 | .593 |
| Trevor Hoffman | Det | cl | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 19.6 | .670 |
| D.J. Houlton | KCR | sp | 25 | 10 | 0 | .000 | 0 | 1 | .100 | 29 | 2.9 | 14 | 5 | .357 | 55.4 | .591 |
| J.P. Howell* |   | sp | 22 | 12 | 0 | .000 | 0 | 7 | .583 | 48 | 4.0 | 10 | 2 | .200 | 96.9 | .571 |
| Luke Hudson | Was | sp | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 3 | 1.000 | 8.0 | .688 |
| Tim Hudson | Det | sp | 29 | 32 | 5 | .156 | 2 | 15 | .469 | 142 | 4.4 | 19 | 6 | .316 | 96.0 | .642 |
| Kazuhisa Ishii* | Oak | sp | 31 | 20 | 0 | .000 | 0 | 7 | .350 | 82 | 4.1 | 19 | 9 | .474 | 82.0 | .596 |
| Jason Isringhausen | Sea | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 | 17.9 | .632 |
| Edwin Jackson | Min | sp | 21 | 8 | 0 | .000 | 0 | 2 | .250 | 36 | 4.5 | 9 | 6 | .667 | 99.9 | .569 |
| Chuck James* | Bos | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 18.7 | .626 |
| Bobby Jenks | KCR | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 0 | .000 | 30.4 | .636 |
| Jason Johnson | Tex | sp | 31 | 24 | 4 | .167 | 1 | 12 | .500 | 172 | 7.2 | 13 | 4 | .308 | 98.6 | .648 |
| Tyler Johnson* | Sea | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 19.0 | .579 |
| Jorge Julio | Cle | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 2 | .095 | 18.9 | .625 |
| Scott Kazmir* | Bos | sp | 21 | 29 | 1 | .034 | 0 | 17 | .586 | 88 | 3.0 | 22 | 4 | .182 | 107.4 | .581 |
| Joe Kennedy* | Min | sp | 26 | 30 | 2 | .067 | 0 | 10 | .333 | 131 | 4.4 | 20 | 10 | .500 | 93.9 | .628 |
| Byung-Hyun Kim | LAA | sp | 26 | 3 | 1 | .333 | 0 | 1 | .333 | 7 | 2.3 | 2 | 1 | .500 | 80.3 | .629 |
| Steve Kline* | Cle | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 5 | .417 | 18.5 | .618 |
| Dae-Sung Koo* | Sea | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 1 | .091 | 26.7 | .621 |
| Mike Koplove | Tor | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 6 | .500 | 23.7 | .629 |
| Hong-Chih Kuo* | Bos | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 41.7 | .600 |
| John Lackey | Bal | sp | 26 | 32 | 3 | .094 | 1 | 16 | .500 | 146 | 4.6 | 26 | 8 | .308 | 98.1 | .611 |
| Brandon League | Min | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 3 | .600 | 37.3 | .554 |
| Brad Lidge | ChW | cl | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 19.4 | .635 |
| Francisco Liriano* | Min | sp | 21 | 8 | 0 | .000 | 0 | 3 | .375 | 25 | 3.1 | 3 | 1 | .333 | 94.4 | .640 |
| Esteban Loaiza | LAA | sp | 33 | 34 | 4 | .118 | 3 | 16 | .471 | 111 | 3.3 | 25 | 12 | .480 | 94.8 | .648 |
| Kameron Loe | NYY | mr | 23 | 1 | 0 | .000 | 0 | 1 | 1.000 | 1 | 1.0 | 1 | 0 | .000 | 33.4 | .631 |
| Braden Looper | LAA | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 23.6 | .641 |
| Rodrigo Lopez | NYY | sp | 29 | 32 | 5 | .156 | 2 | 16 | .500 | 164 | 5.1 | 26 | 10 | .385 | 99.3 | .624 |
| Derek Lowe | Mtl | sp | 32 | 35 | 3 | .086 | 2 | 20 | .571 | 206 | 5.9 | 25 | 3 | .120 | 99.7 | .636 |
| Greg Maddux | Bal | sp | 39 | 20 | 4 | .200 | 0 | 10 | .500 | 103 | 5.2 | 11 | 5 | .455 | 96.8 | .689 |
| Ryan Madson | NYY | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 5 | .200 | 21.7 | .647 |
| Mike Maroth* | Tor | sp | 27 | 33 | 2 | .061 | 1 | 15 | .455 | 141 | 4.3 | 16 | 12 | .750 | 89.8 | .627 |
| Damaso Marte* | Det | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 5 | .294 | 25.3 | .566 |
| Darrell May* | ChW | mr | 33 | 2 | 0 | .000 | 0 | 0 | .000 | 7 | 3.5 | 4 | 1 | .250 | 31.1 | .638 |
| Dustin McGowan | Cle | sp | 23 | 11 | 0 | .000 | 0 | 4 | .364 | 54 | 4.9 | 14 | 6 | .429 | 85.2 | .588 |
| Brian Meadows | Mtl | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 7 | .467 | 17.5 | .682 |
| Kent Mercker* | Tex | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 0 | .000 | 19.0 | .645 |
| Wade Miller | Bos | sp | 28 | 17 | 0 | .000 | 0 | 8 | .471 | 61 | 3.6 | 12 | 1 | .083 | 98.4 | .592 |
| Brian Moehler | Det | sp | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 0 | .000 | 42.8 | .675 |
| Matt Morris |   | sp | 30 | 32 | 2 | .063 | 1 | 19 | .594 | 153 | 4.8 | 20 | 12 | .600 | 98.5 | .660 |
| Mark Mulder* | Was | sp | 27 | 31 | 2 | .065 | 0 | 16 | .516 | 165 | 5.3 | 22 | 8 | .364 | 93.5 | .613 |
| Terry Mulholland* | LAA | mr | 42 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 11.8 | .652 |
| Scott Munter | NYY | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 5 | .192 | 20.7 | .600 |
| Mike Mussina | Oak | sp | 36 | 32 | 2 | .063 | 0 | 16 | .500 | 151 | 4.7 | 15 | 6 | .400 | 94.1 | .647 |
| Brett Myers | Oak | sp | 24 | 34 | 5 | .147 | 0 | 25 | .735 | 159 | 4.7 | 15 | 5 | .333 | 109.7 | .643 |
| Joe Nathan | Was | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 3 | .250 | 19.3 | .617 |
| Blaine Neal | ChW | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 31.0 | .640 |
| Hideo Nomo | Bos | sp | 36 | 16 | 1 | .063 | 0 | 6 | .375 | 57 | 3.6 | 7 | 3 | .429 | 101.1 | .572 |
| Ramon Ortiz | NYY | sp | 32 | 31 | 3 | .097 | 0 | 13 | .419 | 141 | 4.5 | 16 | 10 | .625 | 92.3 | .633 |
| Vicente Padilla | LAA | sp | 27 | 30 | 0 | .000 | 0 | 13 | .433 | 113 | 3.8 | 15 | 4 | .267 | 96.2 | .588 |
| Jonathan Papelbon | Min | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 4 | .267 | 21.0 | .610 |
| Chan Ho Park | Tor | sp | 32 | 21 | 0 | .000 | 0 | 7 | .333 | 126 | 6.0 | 22 | 10 | .455 | 88.8 | .586 |
| Jake Peavy | ChW | sp | 24 | 32 | 9 | .281 | 2 | 23 | .719 | 145 | 4.5 | 14 | 4 | .286 | 105.0 | .649 |
| Joel Peralta | Tex | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 3 | .750 | 23.9 | .629 |
| Odalis Perez* | Min | sp | 28 | 23 | 0 | .000 | 0 | 12 | .522 | 84 | 3.7 | 13 | 7 | .538 | 94.4 | .657 |
| Oliver Perez* | LAA | sp | 23 | 13 | 0 | .000 | 0 | 6 | .462 | 48 | 3.7 | 5 | 2 | .400 | 95.5 | .569 |
| Tommy Phelps* | Bos | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 4 | .333 | 25.7 | .592 |
| Joel Pineiro | Min | sp | 26 | 32 | 3 | .094 | 0 | 16 | .500 | 111 | 3.5 | 26 | 11 | .423 | 100.6 | .642 |
| Cliff Politte | ChW | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 0 | .000 | 23.0 | .635 |
| Mark Prior | KCR | sp | 24 | 29 | 3 | .103 | 1 | 22 | .759 | 115 | 4.0 | 21 | 4 | .190 | 110.7 | .626 |
| Scott Proctor | NYY | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 | 34.4 | .625 |
| Paul Quantrill | LAA | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 36.8 | .679 |
| Brad Radke | Mtl | sp | 32 | 32 | 1 | .031 | 1 | 14 | .438 | 174 | 5.4 | 18 | 2 | .111 | 99.5 | .684 |
| Horacio Ramirez* |   | sp | 25 | 34 | 2 | .059 | 0 | 16 | .471 | 175 | 5.1 | 17 | 8 | .471 | 94.1 | .612 |
| Chris Ray | Cle | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 4 | .308 | 19.0 | .630 |
| Steve Reed | Oak | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 19.8 | .607 |
| Chris Reitsma | Was | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 11 | .478 | 21.3 | .678 |
| Mike Remlinger* | Cle | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 34 | 8 | .235 | 15.3 | .639 |
| Chris Resop | Cle | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 28.7 | .640 |
| Anthony Reyes | KCR | mr | 23 | 1 | 0 | .000 | 0 | 1 | 1.000 | 3 | 3.0 | 0 | 0 | .000 | 53.3 | .657 |
| Dennys Reyes* | ChW | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 2 | .095 | 24.1 | .571 |
| Matt Riley* | Min | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 5 | .500 | 28.7 | .532 |
| Ricardo Rincon* | Mtl | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 2 | .125 | 16.8 | .584 |
| Mariano Rivera | Tor | cl | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 18.2 | .662 |
| Fernando Rodney | Min | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 | 24.6 | .623 |
| Francisco Rodriguez | Tor | cl | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 5 | .263 | 22.9 | .602 |
| Kenny Rogers* | Bal | sp | 40 | 30 | 4 | .133 | 0 | 18 | .600 | 162 | 5.4 | 24 | 8 | .333 | 99.1 | .627 |
| J.C. Romero* | Sea | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 7 | .259 | 21.2 | .569 |
| Kirk Rueter* | KCR | sp | 34 | 1 | 0 | .000 | 0 | 1 | 1.000 | 1 | 1.0 | 1 | 1 | 1.000 | 73.0 | .685 |
| Glendon Rusch* | NYY | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 3 | .750 | 34.8 | .622 |
| B.J. Ryan* | Was | cl | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 2 | .133 | 23.3 | .610 |
| C.C. Sabathia* | KCR | sp | 24 | 31 | 7 | .226 | 4 | 25 | .806 | 135 | 4.4 | 14 | 1 | .071 | 109.9 | .642 |
| Duaner Sanchez | Mtl | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 6 | .316 | 19.6 | .604 |
| Johan Santana* | Sea | sp | 26 | 33 | 6 | .182 | 2 | 21 | .636 | 130 | 3.9 | 20 | 3 | .150 | 106.5 | .659 |
| Julio Santana | Sea | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 5 | .833 | 27.8 | .588 |
| Victor Santos | Sea | sp | 28 | 24 | 1 | .042 | 0 | 8 | .333 | 103 | 4.3 | 23 | 6 | .261 | 83.8 | .637 |
| Scott Sauerbeck* | ChW | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 7 | .636 | 16.8 | .585 |
| Joe Saunders* | Cle | sp | 24 | 6 | 0 | .000 | 0 | 1 | .167 | 21 | 3.5 | 0 | 0 | .000 | 87.2 | .587 |
| Scott Schoeneweis* | Bal | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 4 | .160 | 16.9 | .603 |
| Rudy Seanez | Tex | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 7 | .280 | 23.8 | .628 |
| Bobby Seay* | LAA | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 39.0 | .615 |
| Aaron Sele | Sea | sp | 35 | 19 | 0 | .000 | 0 | 5 | .263 | 131 | 6.9 | 20 | 6 | .300 | 78.7 | .624 |
| Ben Sheets | Oak | sp | 26 | 26 | 8 | .308 | 3 | 16 | .615 | 118 | 4.5 | 12 | 3 | .250 | 104.3 | .664 |
| George Sherrill* | KCR | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 4 | .222 | 20.8 | .594 |
| Brian Shouse* | Tor | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 7 | .280 | 18.0 | .609 |
| Rafael Soriano | Min | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 26.2 | .615 |
| Justin Speier | Sea | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 6 | .261 | 21.5 | .666 |
| Ryan Speier | Tor | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 22.5 | .667 |
| Mike Stanton* | Mtl | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 11.0 | .636 |
| Huston Street | NYY | cl | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 16.3 | .631 |
| Tanyon Sturtze | Tex | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 | 28.6 | .584 |
| Jeff Suppan | Was | sp | 30 | 33 | 2 | .061 | 1 | 20 | .606 | 164 | 5.0 | 28 | 14 | .500 | 94.1 | .617 |
| Jack Taschner* | NYY | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 20.3 | .543 |
| Brett Tomko | NYY | sp | 32 | 32 | 3 | .094 | 0 | 12 | .375 | 158 | 4.9 | 27 | 16 | .593 | 99.3 | .651 |
| Salomon Torres | Det | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 4 | .182 | 23.5 | .618 |
| Josh Towers | Tex | sp | 28 | 34 | 2 | .059 | 2 | 22 | .647 | 168 | 4.9 | 33 | 20 | .606 | 90.3 | .679 |
| Ugueth Urbina | KCR | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 5 | .455 | 23.2 | .612 |
| Ismael Valdez | Cle | sp | 31 | 8 | 0 | .000 | 0 | 1 | .125 | 24 | 3.0 | 13 | 6 | .462 | 58.3 | .634 |
| Jose Valverde | Mtl | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 5 | .455 | 23.1 | .632 |
| Claudio Vargas | Cle | sp | 27 | 27 | 1 | .037 | 1 | 14 | .519 | 85 | 3.1 | 23 | 8 | .348 | 87.3 | .625 |
| Justin Verlander | Cle | sp | 22 | 6 | 1 | .167 | 0 | 2 | .333 | 24 | 4.0 | 4 | 1 | .250 | 86.2 | .631 |
| Luis Vizcaino | NYY | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 1 | .077 | 32.0 | .603 |
| Ryan Vogelsong | Was | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 2 | .125 | 33.2 | .579 |
| Edison Volquez | Cle | sp | 21 | 3 | 0 | .000 | 0 | 0 | .000 | 10 | 3.3 | 6 | 2 | .333 | 58.0 | .600 |
| Ryan Wagner | Bos | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 9 | .391 | 24.1 | .638 |
| Tim Wakefield | Tex | sp | 38 | 32 | 1 | .031 | 0 | 15 | .469 | 168 | 5.3 | 27 | 9 | .333 | 97.1 | .629 |
| Jamie Walker* | Mtl | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 7 | .412 | 19.4 | .626 |
| John Wasdin | Bal | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 4 | .667 | 43.1 | .660 |
| Jarrod Washburn* | Det | sp | 30 | 31 | 4 | .129 | 1 | 17 | .548 | 132 | 4.3 | 20 | 6 | .300 | 97.6 | .625 |
| Jeff Weaver | Sea | sp | 28 | 34 | 3 | .088 | 1 | 18 | .529 | 202 | 5.9 | 24 | 5 | .208 | 95.6 | .661 |
| Brandon Webb | Det | sp | 26 | 35 | 7 | .200 | 3 | 22 | .629 | 158 | 4.5 | 21 | 7 | .333 | 105.7 | .643 |
| David Wells* | Bal | sp | 42 | 31 | 2 | .065 | 0 | 14 | .452 | 195 | 6.3 | 27 | 12 | .444 | 87.1 | .678 |
| Jake Westbrook | Tex | sp | 27 | 34 | 2 | .059 | 2 | 17 | .500 | 165 | 4.9 | 27 | 9 | .333 | 97.5 | .647 |
| Dan Wheeler |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 17.6 | .677 |
| Rick White | Cle | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 43 | 14 | .326 | 16.2 | .618 |
| Dave Williams* | KCR | sp | 26 | 30 | 2 | .067 | 1 | 18 | .600 | 128 | 4.3 | 23 | 9 | .391 | 88.9 | .626 |
| Jerome Williams |   | sp | 23 | 23 | 2 | .087 | 0 | 12 | .522 | 123 | 5.3 | 22 | 13 | .591 | 86.7 | .615 |
| Woody Williams | ChW | sp | 38 | 30 | 3 | .100 | 0 | 15 | .500 | 135 | 4.5 | 21 | 8 | .381 | 95.3 | .621 |
| Scott Williamson | Min | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 23.1 | .645 |
| Dontrelle Willis* | Was | sp | 23 | 36 | 11 | .306 | 4 | 29 | .806 | 113 | 3.1 | 22 | 4 | .182 | 107.5 | .654 |
| C.J. Wilson* | Min | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 8 | .400 | 30.0 | .617 |
| Paul Wilson | Det | sp | 32 | 2 | 0 | .000 | 0 | 0 | .000 | 14 | 7.0 | 3 | 2 | .667 | 83.0 | .586 |
| Matt Wise | ChW | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 29.8 | .656 |
| Kerry Wood | Mtl | mr | 28 | 18 | 1 | .056 | 0 | 13 | .722 | 99 | 5.5 | 6 | 2 | .333 | 96.3 | .636 |
| Tim Worrell | ChW | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 | 24.4 | .668 |
| Jamey Wright | NYY | sp | 30 | 23 | 2 | .087 | 0 | 7 | .304 | 89 | 3.9 | 27 | 9 | .333 | 89.2 | .590 |
| Keiichi Yabu | Cle | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 5 | .238 | 34.7 | .621 |
| Esteban Yan | ChW | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 3 | .600 | 26.3 | .603 |
| Victor Zambrano | Det | sp | 29 | 24 | 1 | .042 | 0 | 12 | .500 | 92 | 3.8 | 21 | 6 | .286 | 100.0 | .604 |
| Barry Zito* | ChW | sp | 27 | 34 | 6 | .176 | 3 | 23 | .676 | 199 | 5.9 | 28 | 8 | .286 | 111.6 | .608 |
| Relief |
| Name | Team | P | Age | SVO | S | SV% | BS | BS% | HLD | IR | IRS | IR% | G | GR | GF | NP/G | STR% |
| Jeremy Accardo | ChW | mr | 23 | 1 | 0 | .000 | 1 | 1.000 | 0 | 3 | 1 | .333 | 6 | 6 | 2 | 22.7 | .610 |
| Jose Acevedo | ChW | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 0 | 12 | 6 | .500 | 14 | 14 | 5 | 34.9 | .650 |
| Jeremy Affeldt* | Bos | mr | 26 | 11 | 6 | .545 | 5 | .455 | 7 | 34 | 12 | .353 | 54 | 54 | 29 | 24.3 | .591 |
| Wilson Alvarez* | Det | mr | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 76.0 | .658 |
| Brian Anderson* | KCR | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 1 | 1 | 52.7 | .677 |
| Matt Anderson | Min | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 10 | 6 | .600 | 9 | 9 | 2 | 28.8 | .510 |
| Greg Aquino | Bal | mr | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 28 | 12 | .429 | 31 | 31 | 8 | 29.6 | .594 |
| Ezequiel Astacio | Min | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 | 92.3 | .649 |
| Luis Ayala | Was | mr | 27 | 3 | 2 | .667 | 1 | .333 | 9 | 32 | 9 | .281 | 51 | 51 | 15 | 17.0 | .660 |
| Manny Aybar | Bos | mr | 33 | 0 | 0 | .000 | 0 | .000 | 2 | 36 | 15 | .417 | 30 | 30 | 11 | 30.4 | .657 |
| Danys Baez | Sea | cl | 27 | 7 | 2 | .286 | 4 | .571 | 7 | 65 | 31 | .477 | 60 | 60 | 18 | 24.6 | .615 |
| James Baldwin | Oak | mr | 33 | 3 | 1 | .333 | 2 | .667 | 2 | 16 | 3 | .188 | 20 | 20 | 12 | 28.3 | .638 |
| Cliff Bartosh* | Bos | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 1 | 28 | 10 | .357 | 29 | 29 | 11 | 28.0 | .601 |
| Jonah Bayliss | Bos | mr | 24 | 3 | 2 | .667 | 0 | .000 | 0 | 10 | 3 | .300 | 14 | 14 | 8 | 21.9 | .595 |
| Josh Beckett | KCR | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 101.3 | .628 |
| Armando Benitez | ChW | cl | 32 | 1 | 1 | 1.000 | 0 | .000 | 5 | 24 | 7 | .292 | 18 | 18 | 6 | 20.7 | .584 |
| Joaquin Benoit | Tor | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 11 | 1 | 1 | 96.8 | .628 |
| Kris Benson | ChW | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 | 97.8 | .645 |
| Jason Bergmann | KCR | mr | 23 | 2 | 2 | 1.000 | 0 | .000 | 3 | 11 | 3 | .273 | 13 | 12 | 7 | 28.9 | .580 |
| Rafael Betancourt | Oak | mr | 30 | 41 | 33 | .805 | 8 | .195 | 1 | 37 | 10 | .270 | 57 | 57 | 50 | 19.8 | .652 |
| Jeremy Bonderman | Oak | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 94.9 | .623 |
| Joe Borowski | Mtl | mr | 34 | 10 | 5 | .500 | 4 | .400 | 3 | 30 | 11 | .367 | 43 | 43 | 29 | 16.1 | .656 |
| Ricky Bottalico | Bos | mr | 35 | 6 | 4 | .667 | 2 | .333 | 4 | 26 | 10 | .385 | 46 | 46 | 22 | 23.6 | .599 |
| Blaine Boyer | Det | mr | 23 | 0 | 0 | .000 | 0 | .000 | 2 | 20 | 6 | .300 | 21 | 21 | 11 | 24.4 | .616 |
| Chad Bradford | Oak | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 1 | 12 | 4 | .333 | 20 | 20 | 4 | 18.5 | .650 |
| Craig Breslow* | Bal | mr | 24 | 1 | 1 | 1.000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 3 | 1 | 14.7 | .568 |
| Doug Brocail | Tor | mr | 38 | 3 | 0 | .000 | 2 | .667 | 3 | 61 | 30 | .492 | 62 | 62 | 10 | 30.7 | .602 |
| Jim Brower | Cle | mr | 32 | 1 | 0 | .000 | 1 | 1.000 | 0 | 21 | 6 | .286 | 33 | 33 | 13 | 26.1 | .601 |
| Kevin Brown | Mtl | sp | 40 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 86.0 | .628 |
| Brian Bruney | NYY | cl | 23 | 0 | 0 | .000 | 0 | .000 | 1 | 16 | 8 | .500 | 14 | 14 | 8 | 33.8 | .558 |
| Ryan Bukvich | Min | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 1 | 4 | 2 | .500 | 7 | 7 | 3 | 30.4 | .516 |
| Bryan Bullington | LAA | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 2 | 2 | 2 | 35.0 | .571 |
| Nate Bump | Det | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 0 | 4 | 1 | .250 | 6 | 6 | 3 | 26.2 | .618 |
| Paul Byrd | Tor | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 93.5 | .693 |
| Tim Byrdak* | Sea | mr | 31 | 1 | 0 | .000 | 1 | 1.000 | 1 | 18 | 4 | .222 | 19 | 19 | 5 | 24.8 | .569 |
| Daniel Cabrera | Cle | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 99.9 | .591 |
| Matt Cain | NYY | sp | 20 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 108.8 | .630 |
| Kiko Calero | Bal | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 7 | 29 | 13 | .448 | 46 | 46 | 25 | 24.7 | .641 |
| Shawn Camp | KCR | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 3 | 3 | 0 | 18.7 | .679 |
| Matt Capps | Sea | mr | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 1 | 1 | 0 | 40.0 | .575 |
| Chris Capuano* | NYY | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 39 | 0 | 0 | 103.7 | .605 |
| Chris Carpenter | Tex | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 38 | 0 | 0 | 99.8 | .652 |
| Hector Carrasco | LAA | mr | 35 | 10 | 8 | .800 | 2 | .200 | 10 | 40 | 16 | .400 | 63 | 61 | 34 | 25.3 | .624 |
| Lance Carter | Mtl | mr | 30 | 0 | 0 | .000 | 0 | .000 | 1 | 24 | 6 | .250 | 32 | 32 | 13 | 31.8 | .644 |
| Marcos Carvajal | KCR | mr | 20 | 2 | 0 | .000 | 2 | 1.000 | 0 | 25 | 5 | .200 | 33 | 33 | 12 | 35.8 | .615 |
| Frank Castillo | KCR | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 95.0 | .537 |
| Gustavo Chacin* | Bal | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 92.6 | .617 |
| Shawn Chacon | Det | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 96.6 | .604 |
| Bruce Chen* | Cle | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 4 | 1.000 | 33 | 2 | 0 | 92.7 | .613 |
| Jason Christiansen* | Mtl | mr | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 2 | .333 | 4 | 4 | 1 | 15.3 | .689 |
| Vinnie Chulk | Tex | mr | 26 | 2 | 2 | 1.000 | 0 | .000 | 4 | 21 | 11 | .524 | 31 | 31 | 19 | 23.6 | .613 |
| Brandon Claussen* | LAA | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 94.5 | .628 |
| Jesus Colome | Cle | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 5 | 1.000 | 8 | 8 | 4 | 21.9 | .629 |
| Bartolo Colon | Sea | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 100.3 | .644 |
| Brian Cooper | Tor | mr | 30 | 1 | 1 | 1.000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 2 | 19.0 | .553 |
| Francisco Cordero | Tex | cl | 30 | 35 | 27 | .771 | 8 | .229 | 0 | 39 | 20 | .513 | 51 | 51 | 45 | 20.5 | .605 |
| Doug Creek* | Was | mr | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 5 | .833 | 8 | 8 | 3 | 21.3 | .600 |
| Juan Cruz | Min | mr | 26 | 4 | 0 | .000 | 2 | .500 | 9 | 41 | 22 | .537 | 64 | 64 | 19 | 29.7 | .589 |
| Jason Davis | KCR | mr | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 2 | 1 | .500 | 6 | 2 | 0 | 60.3 | .630 |
| Zach Day | Bal | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 2 | .667 | 9 | 7 | 4 | 32.9 | .557 |
| Valerio de los Santos* | KCR | mr | 32 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 0 | .000 | 3 | 3 | 0 | 7.7 | .522 |
| Mike DeJean | Tor | mr | 34 | 6 | 4 | .667 | 1 | .167 | 10 | 42 | 18 | .429 | 61 | 61 | 23 | 23.2 | .618 |
| Manny Delcarmen | Cle | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 10 | 10 | 3 | 21.5 | .586 |
| Ryan Dempster | LAA | cl | 28 | 22 | 16 | .727 | 5 | .227 | 1 | 23 | 5 | .217 | 45 | 45 | 31 | 21.2 | .602 |
| Elmer Dessens | Sea | mr | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 91.6 | .663 |
| Joey Devine | Bos | mr | 21 | 2 | 0 | .000 | 2 | 1.000 | 0 | 16 | 6 | .375 | 16 | 16 | 7 | 29.6 | .597 |
| R.A. Dickey | KCR | mr | 30 | 0 | 0 | .000 | 0 | .000 | 1 | 1 | 0 | .000 | 6 | 2 | 0 | 77.8 | .559 |
| Craig Dingman | Det | mr | 31 | 0 | 0 | .000 | 0 | .000 | 3 | 11 | 1 | .091 | 14 | 14 | 8 | 23.4 | .682 |
| Juan Dominguez | Min | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 101.2 | .645 |
| Octavio Dotel | Oak | cl | 31 | 1 | 1 | 1.000 | 0 | .000 | 5 | 16 | 5 | .313 | 19 | 19 | 5 | 23.4 | .590 |
| Scott Downs* | LAA | sp | 29 | 2 | 0 | .000 | 1 | .500 | 6 | 20 | 3 | .150 | 38 | 37 | 19 | 26.4 | .604 |
| Zach Duke* | Tor | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 1 | 1 | 93.2 | .635 |
| Adam Eaton | LAA | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 98.7 | .631 |
| Scott Erickson | KCR | mr | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 71.5 | .552 |
| Kelvim Escobar | Min | mr | 29 | 1 | 0 | .000 | 1 | 1.000 | 5 | 32 | 13 | .406 | 35 | 35 | 18 | 35.7 | .623 |
| Mike Esposito | Bos | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 71.8 | .599 |
| Shawn Estes* | Tor | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 92.6 | .612 |
| Seth Etherton | ChW | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 | 104.4 | .599 |
| Dana Eveland* | Cle | mr | 21 | 1 | 1 | 1.000 | 0 | .000 | 2 | 17 | 5 | .294 | 25 | 25 | 9 | 27.6 | .588 |
| Scott Eyre* | Oak | mr | 33 | 8 | 1 | .125 | 6 | .750 | 22 | 38 | 14 | .368 | 67 | 67 | 26 | 18.9 | .619 |
| Kyle Farnsworth | Det | mr | 29 | 11 | 6 | .545 | 5 | .455 | 15 | 49 | 12 | .245 | 63 | 63 | 35 | 23.7 | .615 |
| Jeff Fassero* | Tex | mr | 42 | 0 | 0 | .000 | 0 | .000 | 7 | 39 | 16 | .410 | 46 | 46 | 18 | 26.2 | .605 |
| Ron Flores* | KCR | mr | 25 | 3 | 3 | 1.000 | 0 | .000 | 1 | 7 | 2 | .286 | 12 | 12 | 7 | 18.1 | .659 |
| Josh Fogg | Bal | sp | 28 | 1 | 0 | .000 | 0 | .000 | 0 | 9 | 2 | .222 | 24 | 11 | 4 | 56.9 | .643 |
| Keith Foulke | Oak | cl | 32 | 1 | 0 | .000 | 0 | .000 | 0 | 11 | 7 | .636 | 24 | 24 | 11 | 23.7 | .614 |
| Jeff Francis* | Bos | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 98.7 | .600 |
| Brian Fuentes* | Bal | cl | 29 | 20 | 15 | .750 | 4 | .200 | 4 | 26 | 8 | .308 | 48 | 48 | 29 | 20.3 | .633 |
| Jairo Garcia | Bos | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 1 | 49.0 | .510 |
| Jon Garland | Mtl | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 97.1 | .643 |
| Dave Gassner* | Sea | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 3 | 1 | 1 | 50.0 | .647 |
| Geoff Geary | LAA | mr | 28 | 1 | 1 | 1.000 | 0 | .000 | 1 | 26 | 9 | .346 | 39 | 39 | 12 | 35.2 | .606 |
| Matt Ginter | KCR | mr | 27 | 1 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 2 | 2 | 1 | 2.5 | .600 |
| Gary Glover | KCR | sp | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 7 | 1 | .143 | 18 | 6 | 4 | 65.2 | .647 |
| Jimmy Gobble* | Cle | mr | 23 | 0 | 0 | .000 | 0 | .000 | 1 | 8 | 3 | .375 | 34 | 10 | 1 | 65.1 | .582 |
| Jeremi Gonzalez | Oak | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 9 | 4 | .444 | 17 | 10 | 4 | 58.7 | .633 |
| Tom Gordon | Bal | mr | 37 | 8 | 2 | .250 | 3 | .375 | 20 | 39 | 8 | .205 | 76 | 76 | 21 | 22.5 | .621 |
| John Grabow* | KCR | mr | 26 | 9 | 5 | .556 | 4 | .444 | 9 | 39 | 18 | .462 | 50 | 50 | 21 | 23.1 | .607 |
| Danny Graves | KCR | cl | 31 | 1 | 0 | .000 | 0 | .000 | 1 | 2 | 2 | 1.000 | 4 | 4 | 0 | 13.5 | .500 |
| Zack Greinke | Bos | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 89.4 | .629 |
| Buddy Groom* | Sea | mr | 39 | 2 | 0 | .000 | 0 | .000 | 1 | 9 | 1 | .111 | 7 | 7 | 0 | 4.3 | .667 |
| Kevin Gryboski | Bal | mr | 31 | 0 | 0 | .000 | 0 | .000 | 1 | 5 | 2 | .400 | 7 | 7 | 4 | 27.6 | .575 |
| Eddie Guardado* |   | cl | 34 | 16 | 9 | .563 | 6 | .375 | 9 | 38 | 12 | .316 | 52 | 52 | 24 | 21.6 | .677 |
| John Halama* | KCR | mr | 33 | 1 | 1 | 1.000 | 0 | .000 | 2 | 16 | 5 | .313 | 20 | 18 | 5 | 39.9 | .644 |
| Brad Halsey* | Mtl | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 93.0 | .647 |
| Mike Hampton* | Det | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 93.3 | .604 |
| Craig Hansen | Bos | mr | 21 | 1 | 0 | .000 | 1 | 1.000 | 0 | 4 | 2 | .500 | 8 | 8 | 3 | 28.6 | .607 |
| Aaron Harang | Was | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 107.5 | .654 |
| Chad Harville | Sea | mr | 28 | 4 | 2 | .500 | 0 | .000 | 2 | 27 | 7 | .259 | 35 | 35 | 17 | 24.8 | .585 |
| Shigetoshi Hasegawa | LAA | mr | 36 | 2 | 1 | .500 | 0 | .000 | 0 | 45 | 20 | .444 | 58 | 58 | 25 | 30.9 | .641 |
| LaTroy Hawkins | Cle | mr | 32 | 28 | 18 | .643 | 10 | .357 | 7 | 30 | 8 | .267 | 59 | 59 | 42 | 19.0 | .627 |
| Aaron Heilman | Oak | mr | 26 | 1 | 0 | .000 | 0 | .000 | 4 | 27 | 8 | .296 | 54 | 43 | 12 | 44.9 | .635 |
| Mark Hendrickson* | LAA | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 | 93.3 | .629 |
| Clay Hensley | Bal | mr | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 7 | 1 | .143 | 5 | 5 | 2 | 30.6 | .556 |
| Dustin Hermanson | Bal | cl | 32 | 20 | 15 | .750 | 4 | .200 | 7 | 33 | 10 | .303 | 57 | 57 | 35 | 19.9 | .632 |
| Felix Hernandez | Min | sp | 19 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 107.9 | .629 |
| Livan Hernandez | Was | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 99.5 | .631 |
| Orlando Hernandez | Tor | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 92.4 | .605 |
| Roberto Hernandez | Tex | mr | 40 | 6 | 4 | .667 | 2 | .333 | 7 | 32 | 11 | .344 | 42 | 42 | 18 | 24.2 | .608 |
| Runelvys Hernandez | ChW | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 90.4 | .593 |
| Trevor Hoffman | Det | cl | 37 | 43 | 41 | .953 | 2 | .047 | 1 | 29 | 2 | .069 | 54 | 54 | 48 | 19.6 | .670 |
| D.J. Houlton | KCR | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 18 | 8 | 5 | 55.4 | .591 |
| J.P. Howell* |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 96.9 | .571 |
| Luke Hudson | Was | sp | 28 | 1 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 1 | 8.0 | .688 |
| Tim Hudson | Det | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 96.0 | .642 |
| Kazuhisa Ishii* | Oak | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 | 82.0 | .596 |
| Jason Isringhausen | Sea | cl | 32 | 40 | 33 | .825 | 7 | .175 | 1 | 35 | 8 | .229 | 60 | 60 | 53 | 17.9 | .632 |
| Edwin Jackson | Min | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 99.9 | .569 |
| Chuck James* | Bos | mr | 23 | 1 | 1 | 1.000 | 0 | .000 | 2 | 4 | 1 | .250 | 7 | 7 | 5 | 18.7 | .626 |
| Bobby Jenks | KCR | mr | 24 | 20 | 13 | .650 | 7 | .350 | 4 | 19 | 6 | .316 | 44 | 44 | 30 | 30.4 | .636 |
| Jason Johnson | Tex | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 | 98.6 | .648 |
| Tyler Johnson* | Sea | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 2 | 2 | 1 | 19.0 | .579 |
| Jorge Julio | Cle | mr | 26 | 3 | 1 | .333 | 2 | .667 | 5 | 37 | 16 | .432 | 35 | 35 | 7 | 18.9 | .625 |
| Scott Kazmir* | Bos | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 107.4 | .581 |
| Joe Kennedy* | Min | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 93.9 | .628 |
| Byung-Hyun Kim | LAA | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 1 | 1 | 80.3 | .629 |
| Steve Kline* | Cle | mr | 32 | 7 | 4 | .571 | 3 | .429 | 1 | 30 | 12 | .400 | 35 | 35 | 17 | 18.5 | .618 |
| Dae-Sung Koo* | Sea | mr | 35 | 4 | 2 | .500 | 2 | .500 | 3 | 11 | 4 | .364 | 15 | 15 | 4 | 26.7 | .621 |
| Mike Koplove | Tor | mr | 28 | 2 | 1 | .500 | 0 | .000 | 2 | 17 | 5 | .294 | 30 | 30 | 13 | 23.7 | .629 |
| Hong-Chih Kuo* | Bos | mr | 23 | 1 | 1 | 1.000 | 0 | .000 | 1 | 4 | 0 | .000 | 13 | 13 | 9 | 41.7 | .600 |
| John Lackey | Bal | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 33 | 1 | 1 | 98.1 | .611 |
| Brandon League | Min | mr | 22 | 3 | 1 | .333 | 2 | .667 | 0 | 10 | 5 | .500 | 19 | 19 | 15 | 37.3 | .554 |
| Brad Lidge | ChW | cl | 28 | 34 | 26 | .765 | 8 | .235 | 1 | 29 | 6 | .207 | 47 | 47 | 40 | 19.4 | .635 |
| Francisco Liriano* | Min | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 94.4 | .640 |
| Esteban Loaiza | LAA | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 94.8 | .648 |
| Kameron Loe | NYY | mr | 23 | 1 | 0 | .000 | 1 | 1.000 | 3 | 9 | 4 | .444 | 9 | 8 | 3 | 33.4 | .631 |
| Braden Looper | LAA | cl | 30 | 7 | 6 | .857 | 1 | .143 | 3 | 16 | 7 | .438 | 31 | 31 | 22 | 23.6 | .641 |
| Rodrigo Lopez | NYY | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 99.3 | .624 |
| Derek Lowe | Mtl | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 0 | 0 | 99.7 | .636 |
| Greg Maddux | Bal | sp | 39 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 | 96.8 | .689 |
| Ryan Madson | NYY | mr | 24 | 11 | 5 | .455 | 6 | .545 | 14 | 57 | 20 | .351 | 70 | 70 | 33 | 21.7 | .647 |
| Mike Maroth* | Tor | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 89.8 | .627 |
| Damaso Marte* | Det | mr | 30 | 5 | 1 | .200 | 1 | .200 | 2 | 34 | 16 | .471 | 34 | 34 | 12 | 25.3 | .566 |
| Darrell May* | ChW | mr | 33 | 2 | 2 | 1.000 | 0 | .000 | 2 | 23 | 4 | .174 | 27 | 25 | 15 | 31.1 | .638 |
| Dustin McGowan | Cle | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 2 | .500 | 13 | 2 | 1 | 85.2 | .588 |
| Brian Meadows | Mtl | mr | 29 | 4 | 1 | .250 | 2 | .500 | 4 | 13 | 3 | .231 | 35 | 35 | 14 | 17.5 | .682 |
| Kent Mercker* | Tex | mr | 37 | 1 | 0 | .000 | 1 | 1.000 | 3 | 19 | 9 | .474 | 16 | 16 | 6 | 19.0 | .645 |
| Wade Miller | Bos | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 98.4 | .592 |
| Brian Moehler | Det | sp | 33 | 1 | 0 | .000 | 0 | .000 | 0 | 15 | 6 | .400 | 19 | 19 | 8 | 42.8 | .675 |
| Matt Morris |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 98.5 | .660 |
| Mark Mulder* | Was | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 93.5 | .613 |
| Terry Mulholland* | LAA | mr | 42 | 2 | 0 | .000 | 2 | 1.000 | 1 | 8 | 1 | .125 | 12 | 12 | 5 | 11.8 | .652 |
| Scott Munter | NYY | mr | 25 | 5 | 1 | .200 | 3 | .600 | 5 | 28 | 5 | .179 | 47 | 47 | 21 | 20.7 | .600 |
| Mike Mussina | Oak | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 94.1 | .647 |
| Brett Myers | Oak | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 109.7 | .643 |
| Joe Nathan | Was | cl | 30 | 43 | 36 | .837 | 7 | .163 | 2 | 40 | 13 | .325 | 59 | 59 | 43 | 19.3 | .617 |
| Blaine Neal | ChW | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 2 | .400 | 6 | 6 | 4 | 31.0 | .640 |
| Hideo Nomo | Bos | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 101.1 | .572 |
| Ramon Ortiz | NYY | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 92.3 | .633 |
| Vicente Padilla | LAA | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 96.2 | .588 |
| Jonathan Papelbon | Min | mr | 24 | 2 | 1 | .500 | 0 | .000 | 1 | 31 | 10 | .323 | 28 | 28 | 18 | 21.0 | .610 |
| Chan Ho Park | Tor | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 | 88.8 | .586 |
| Jake Peavy | ChW | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 105.0 | .649 |
| Joel Peralta | Tex | mr | 29 | 1 | 0 | .000 | 0 | .000 | 2 | 16 | 7 | .438 | 18 | 18 | 12 | 23.9 | .629 |
| Odalis Perez* | Min | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 94.4 | .657 |
| Oliver Perez* | LAA | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 95.5 | .569 |
| Tommy Phelps* | Bos | mr | 31 | 1 | 0 | .000 | 1 | 1.000 | 4 | 13 | 3 | .231 | 26 | 26 | 10 | 25.7 | .592 |
| Joel Pineiro | Min | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 100.6 | .642 |
| Cliff Politte | ChW | mr | 31 | 2 | 2 | 1.000 | 0 | .000 | 5 | 20 | 6 | .300 | 31 | 31 | 15 | 23.0 | .635 |
| Mark Prior | KCR | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 110.7 | .626 |
| Scott Proctor | NYY | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 0 | 17 | 9 | .529 | 24 | 24 | 11 | 34.4 | .625 |
| Paul Quantrill | LAA | mr | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 3 | .500 | 6 | 6 | 1 | 36.8 | .679 |
| Brad Radke | Mtl | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 99.5 | .684 |
| Horacio Ramirez* |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 94.1 | .612 |
| Chris Ray | Cle | mr | 23 | 3 | 2 | .667 | 1 | .333 | 8 | 40 | 13 | .325 | 39 | 39 | 17 | 19.0 | .630 |
| Steve Reed | Oak | mr | 40 | 0 | 0 | .000 | 0 | .000 | 1 | 5 | 1 | .200 | 9 | 9 | 6 | 19.8 | .607 |
| Chris Reitsma | Was | mr | 27 | 8 | 4 | .500 | 2 | .250 | 6 | 58 | 27 | .466 | 69 | 69 | 33 | 21.3 | .678 |
| Mike Remlinger* | Cle | mr | 39 | 11 | 1 | .091 | 6 | .545 | 8 | 47 | 18 | .383 | 54 | 54 | 12 | 15.3 | .639 |
| Chris Resop | Cle | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 6 | 6 | 1 | 28.7 | .640 |
| Anthony Reyes | KCR | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 4 | 3 | 2 | 53.3 | .657 |
| Dennys Reyes* | ChW | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 3 | 12 | 3 | .250 | 20 | 20 | 5 | 24.1 | .571 |
| Matt Riley* | Min | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 9 | 4 | .444 | 11 | 11 | 6 | 28.7 | .532 |
| Ricardo Rincon* | Mtl | mr | 35 | 3 | 1 | .333 | 2 | .667 | 7 | 28 | 14 | .500 | 33 | 33 | 12 | 16.8 | .584 |
| Mariano Rivera | Tor | cl | 35 | 38 | 33 | .868 | 4 | .105 | 1 | 41 | 12 | .293 | 68 | 68 | 58 | 18.2 | .662 |
| Fernando Rodney | Min | mr | 28 | 25 | 20 | .800 | 5 | .200 | 2 | 29 | 7 | .241 | 40 | 40 | 32 | 24.6 | .623 |
| Francisco Rodriguez | Tor | cl | 23 | 10 | 4 | .400 | 6 | .600 | 18 | 43 | 22 | .512 | 69 | 69 | 21 | 22.9 | .602 |
| Kenny Rogers* | Bal | sp | 40 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 99.1 | .627 |
| J.C. Romero* | Sea | mr | 29 | 4 | 1 | .250 | 3 | .750 | 9 | 39 | 9 | .231 | 40 | 40 | 7 | 21.2 | .569 |
| Kirk Rueter* | KCR | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 73.0 | .685 |
| Glendon Rusch* | NYY | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 19 | 8 | .421 | 18 | 18 | 5 | 34.8 | .622 |
| B.J. Ryan* | Was | cl | 29 | 10 | 7 | .700 | 3 | .300 | 21 | 47 | 13 | .277 | 67 | 67 | 24 | 23.3 | .610 |
| C.C. Sabathia* | KCR | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 109.9 | .642 |
| Duaner Sanchez | Mtl | mr | 25 | 9 | 6 | .667 | 2 | .222 | 10 | 31 | 11 | .355 | 42 | 42 | 14 | 19.6 | .604 |
| Johan Santana* | Sea | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 106.5 | .659 |
| Julio Santana | Sea | mr | 32 | 4 | 2 | .500 | 2 | .500 | 3 | 12 | 7 | .583 | 11 | 11 | 4 | 27.8 | .588 |
| Victor Santos | Sea | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 1 | 1 | 83.8 | .637 |
| Scott Sauerbeck* | ChW | mr | 33 | 2 | 1 | .500 | 1 | .500 | 4 | 13 | 5 | .385 | 21 | 21 | 7 | 16.8 | .585 |
| Joe Saunders* | Cle | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 87.2 | .587 |
| Scott Schoeneweis* | Bal | mr | 31 | 2 | 0 | .000 | 1 | .500 | 12 | 34 | 8 | .235 | 50 | 50 | 9 | 16.9 | .603 |
| Rudy Seanez | Tex | mr | 36 | 4 | 2 | .500 | 2 | .500 | 9 | 32 | 8 | .250 | 45 | 45 | 18 | 23.8 | .628 |
| Bobby Seay* | LAA | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 1 | 1 | 1 | 39.0 | .615 |
| Aaron Sele | Sea | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 | 78.7 | .624 |
| Ben Sheets | Oak | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 104.3 | .664 |
| George Sherrill* | KCR | mr | 28 | 7 | 1 | .143 | 2 | .286 | 6 | 29 | 7 | .241 | 25 | 25 | 6 | 20.8 | .594 |
| Brian Shouse* | Tor | mr | 36 | 4 | 2 | .500 | 2 | .500 | 9 | 34 | 15 | .441 | 45 | 45 | 18 | 18.0 | .609 |
| Rafael Soriano | Min | mr | 25 | 5 | 2 | .400 | 3 | .600 | 0 | 13 | 6 | .462 | 12 | 12 | 9 | 26.2 | .615 |
| Justin Speier | Sea | mr | 31 | 7 | 4 | .571 | 2 | .286 | 9 | 50 | 8 | .160 | 70 | 70 | 37 | 21.5 | .666 |
| Ryan Speier | Tor | mr | 25 | 1 | 1 | 1.000 | 0 | .000 | 1 | 8 | 1 | .125 | 4 | 4 | 2 | 22.5 | .667 |
| Mike Stanton* | Mtl | mr | 38 | 0 | 0 | .000 | 0 | .000 | 1 | 2 | 0 | .000 | 2 | 2 | 0 | 11.0 | .636 |
| Huston Street | NYY | cl | 21 | 37 | 34 | .919 | 2 | .054 | 1 | 36 | 3 | .083 | 60 | 60 | 51 | 16.3 | .631 |
| Tanyon Sturtze | Tex | mr | 34 | 1 | 1 | 1.000 | 0 | .000 | 0 | 12 | 7 | .583 | 18 | 18 | 10 | 28.6 | .584 |
| Jeff Suppan | Was | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 94.1 | .617 |
| Jack Taschner* | NYY | mr | 27 | 1 | 0 | .000 | 0 | .000 | 1 | 4 | 1 | .250 | 4 | 4 | 0 | 20.3 | .543 |
| Brett Tomko | NYY | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 99.3 | .651 |
| Salomon Torres | Det | mr | 33 | 2 | 2 | 1.000 | 0 | .000 | 5 | 42 | 12 | .286 | 47 | 47 | 17 | 23.5 | .618 |
| Josh Towers | Tex | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 90.3 | .679 |
| Ugueth Urbina | KCR | mr | 31 | 27 | 22 | .815 | 5 | .185 | 7 | 55 | 9 | .164 | 62 | 62 | 46 | 23.2 | .612 |
| Ismael Valdez | Cle | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 9 | 1 | 0 | 58.3 | .634 |
| Jose Valverde | Mtl | mr | 25 | 10 | 5 | .500 | 5 | .500 | 6 | 21 | 6 | .286 | 40 | 40 | 20 | 23.1 | .632 |
| Claudio Vargas | Cle | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 1 | 1 | 87.3 | .625 |
| Justin Verlander | Cle | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 86.2 | .631 |
| Luis Vizcaino | NYY | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 3 | 39 | 17 | .436 | 35 | 35 | 10 | 32.0 | .603 |
| Ryan Vogelsong | Was | mr | 27 | 3 | 2 | .667 | 1 | .333 | 4 | 35 | 11 | .314 | 41 | 41 | 23 | 33.2 | .579 |
| Edison Volquez | Cle | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 5 | 2 | 0 | 58.0 | .600 |
| Ryan Wagner | Bos | mr | 22 | 8 | 6 | .750 | 2 | .250 | 5 | 27 | 7 | .259 | 51 | 51 | 26 | 24.1 | .638 |
| Tim Wakefield | Tex | sp | 38 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 97.1 | .629 |
| Jamie Walker* | Mtl | mr | 33 | 6 | 2 | .333 | 4 | .667 | 9 | 23 | 8 | .348 | 32 | 32 | 10 | 19.4 | .626 |
| John Wasdin | Bal | mr | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 19 | 9 | .474 | 11 | 11 | 2 | 43.1 | .660 |
| Jarrod Washburn* | Det | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 97.6 | .625 |
| Jeff Weaver | Sea | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 95.6 | .661 |
| Brandon Webb | Det | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 0 | 0 | 105.7 | .643 |
| David Wells* | Bal | sp | 42 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 87.1 | .678 |
| Jake Westbrook | Tex | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 97.5 | .647 |
| Dan Wheeler |   | mr | 27 | 25 | 20 | .800 | 5 | .200 | 7 | 31 | 7 | .226 | 66 | 66 | 44 | 17.6 | .677 |
| Rick White | Cle | mr | 36 | 11 | 1 | .091 | 9 | .818 | 20 | 52 | 17 | .327 | 66 | 66 | 16 | 16.2 | .618 |
| Dave Williams* | KCR | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 88.9 | .626 |
| Jerome Williams |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 86.7 | .615 |
| Woody Williams | ChW | sp | 38 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 95.3 | .621 |
| Scott Williamson | Min | mr | 29 | 10 | 6 | .600 | 4 | .400 | 0 | 25 | 8 | .320 | 20 | 20 | 13 | 23.1 | .645 |
| Dontrelle Willis* | Was | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 36 | 0 | 0 | 107.5 | .654 |
| C.J. Wilson* | Min | mr | 24 | 4 | 2 | .500 | 2 | .500 | 4 | 32 | 9 | .281 | 40 | 40 | 16 | 30.0 | .617 |
| Paul Wilson | Det | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 3 | 1 | 0 | 83.0 | .586 |
| Matt Wise | ChW | mr | 29 | 4 | 2 | .500 | 2 | .500 | 1 | 19 | 8 | .421 | 27 | 27 | 19 | 29.8 | .656 |
| Kerry Wood | Mtl | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 96.3 | .636 |
| Tim Worrell | ChW | mr | 37 | 0 | 0 | .000 | 0 | .000 | 1 | 11 | 1 | .091 | 16 | 16 | 8 | 24.4 | .668 |
| Jamey Wright | NYY | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 25 | 2 | 0 | 89.2 | .590 |
| Keiichi Yabu | Cle | mr | 36 | 2 | 1 | .500 | 0 | .000 | 3 | 59 | 20 | .339 | 41 | 41 | 8 | 34.7 | .621 |
| Esteban Yan | ChW | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 13 | 8 | .615 | 22 | 22 | 10 | 26.3 | .603 |
| Victor Zambrano | Det | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 | 100.0 | .604 |
| Barry Zito* | ChW | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 111.6 | .608 |